Guesthouse vacation rentals in Alachua County

Garden Cottage Sanctuary

Our newly constructed cottage is centrally located in the historic Duckpond neighborhood. Enjoy meandering past lovely historic homes, parks, nature trails. Walk downtown Gainesville, take in a play/movie at the historic Hippodrome theater, enjoy a live concert -take a free yoga class at the downtown Bo Diddley plaza! Walk to many fine restaurants- from hip bars, to food trucks and more. Culture, art, nature, history & the University of Florida awaits you here in our serene and peaceful oasis.

Value · Family · Bathroom

Walk to UF! Historic King Bed Loft w/ Private Deck

If you are visiting Gainesville, look no further than Camellia Loft. This historic gem was built in 1924 and has been freshly renovated to bring it into the modern era. Enjoy the birdsong and majestic trees from your private deck overlooking the backyard—or relax inside as light streams through the loft's massive skylights. Only 0.5 miles to UF campus and exactly 1 mile to the stadium, you can easily walk to campus or games. Unwind by the shared fire pit or enjoy cooking on the grill

Value · Family · Cleanliness

Private cottage convenient to downtown and UF.

Quiet, private studio cottage with screened in porch that look out to the spacious yard and gardens. Off street parking, walking distance to downtown, Santa Fe downtown campus, and 2.5+ miles to UF/Shands. Easy accèss to the airport, libraries, museums, local parks, swimming, and biking trails. Kayaking, cave diving, and other activities just a few miles away. Enjoy your stay with a comfortable queen size bed, private bathroom (shower, no tub), internet, coffee, and a modest kitchen.

Location · Value · Long stay

Palm N' Pillow • Guesthouse by UF, HCA-FL & Shands

Private, fully furnished guesthouse in a prime location—just 7 mins to UF Shands & HCA hospitals. 1BR w/ queen bed, full bath, pull-out couch, air mattress (sleeps 5). Full kitchen w/ cookware, in-unit washer/dryer, fast Wi-Fi, TV, dining & chill patio. Ideal for medical professionals, families, or extended stays. Safe neighborhood with quick access to shopping, dining & downtown. Comfort, privacy, and convenience. Free parking included. No smoking or vaping allowed—strict fines apply.

Location · Value · Kitchen

B&B's Downtown Steampunk

Grab a slice of Wow in this turn-of-the century Steampunk design carriage house in Gainesville’s picturesque Bed and Breakfast District. It’s a stone’s throw from downtown’s fine dining, coffeehouses, craft beer breweries, and the famous Bo Diddly Square’s music venue. Check out plays and movies the historic Hippodrome . . . all this is within a walking radius of a few short blocks. Enjoy your restful retreat’s unique style that combines historical elements with science fiction.

Location · Value · View

Swamp Sweet Swamp

400 square foot space located minutes from University Florida Campus,and Downtown Gainesville. Easy access to/from I-75 on Southside of Town. This Bonus Room above the garage is completely separate from the main house. Access is provided through the garage with one parking space available. If 2 parking spaces needed, please contact host. Great location for attending Gator Sports: Football, Basketball, baseball, etc. Enjoy the wildlife at Sweetwater Wetlands across the street!

Family · Value · Wifi

Beautiful 1-Bedroom Guest House Historic District

Brand New One-Bedroom Guest House in the Historic District near Downtown Gainesville. This stylish, centrally-located rental is located in the backyard of our property and was designed by an architect on the historic board in the city of Gainesville, along with our son, who is also an architect. There is a fully-equipped kitchen, full bathroom and a bedroom with a queen-size bed. The ceilings are 9-feet high, giving a feeling of extra space in this 420-sq. foot guest house.

Location · Value · Getting around

Your own private space of peace and quiet.

Keep it simple at this peaceful and centrally-located place. While being only 15 miles from the nightlife of downtown Gainesville, this is country living at it best. With no street lights the stars are bright and easily counted. The mornings are bright and full of the music of bird songs. The cute 2 bedroom apartment (one double bed, two single beds) is on the SECOND FLOOR. It is easy to get lost in the whisper of the trees. This is a place to rest your soul and unwind.

Location · Value · Hospitality

Stylish Private Studio | Walk to UF

NEWLY RENOVATED | WALK TO UF | PRIVATE STUDIO Wake up minutes from campus in a light-filled, mid-century modern studio — just 0.5 miles from UF. Perfect for game days, campus visits, graduations, and hospital stays (2 miles to UF Health Shands & HCA). This private, detached guest house features modern finishes, natural light, a comfortable bed, kitchenette, mini fridge, Smart TV, fast WiFi, and a workspace. Quiet, central location near UF and downtown Gainesville.

Location · Family · Access

Private bed and bath above detached garage.

Close to Paynes Prairie Preserve State Park, Micanopy's unique downtown and a short easy drive to UF campus. North of Micanopy on Highway 441 across from Lake Wauberg. A common private driveway from the highway leads up to our two story home and two story detached garage. Uber not a good option. Good for couples, solo adventurers, and business travelers; and great for Gator friends and fans. Smoke free and no pets please.

Family · Value · Heating

Little Willa- an open plan guesthouse with kitchen

Kick back and relax in this calm, stylish space. Pet friendly and located in the quiet Duckpond neighborhood just a mile walk from the center of downtown Gainesville. Tom Petty Park at the end of our street includes playground, vollleyball net, tennis courts, dog park etc. Gainesville Bike Trail entrance just 1/2 mile from house. Private entrance to guesthouse with shared brick courtyard and parking.

Family · Value · Wifi

Getaway Guesthouse

Cute, detached, studio-style guest house with private entrance. It is quiet and peaceful, but only minutes from the University of Florida, parks, and restaurants. Kitchen w/refrigerator, microwave, toaster oven, coffee-maker, and dining area perfect for enjoying breakfast before exploring. Comfortable Queen-sized bed for a goodnight's sleep.

Value · Family · Sleep quality