
Guesthouse vacation rentals in Yuma County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Yuma County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Relaxing 2 Bedroom Attached Guest House
Stylish and relaxing attached 2Bedroom Guest house.Quiet neighborhood 5 min away from Onvida Yuma Regional center 4 min from Walmart,Starbucks and fast food restaurants. You will also have access to the shared pool and backyard.Pool is not heated but is available all year.Fully stocked kitchen,stacked washer & dryer in unit for your convenience.This apartment is adjacent to another airbnb property.Complete apartment is 100% private.Access to shared pool and backyard. Max guest occupancy 4 people
4.95 out of 5 average rating, 123 reviews
New Daybed, Loft, Patio, & Palm Trees
A miniature apartment-like retreat with residential mini-split. Palm trees surround this little slice of paradise in the desert. The JAMM Wagon (remodeled Class C RV) has all the essentials: bathroom with shower, kitchen, TV, heat/AC, closet, dining table, and 1-2 beds (1 loft & 1 single) to choose from. Plus, covered patio space for your use. Check hours- but you're walking distance from famous "Jac's Whistle Stop Cafe" or burritos from Gonzo's. Enjoy star gazing or soaking up year-round sun.
5.0 out of 5 average rating, 12 reviews
Stunning Santa fe Guest House
Stunning santa fe guest house four unique apartments with one or two bedrooms, each featuring a private kitchenette 🍳, dining area 🍽️, and private terrace or patio. Designed for a serene and peaceful stay. ✨ Enjoy our stunning pool area featuring a pool bar , sunbeds , and grill — perfect for relaxing and soaking up Yuma’s beautiful weather.⚠️ Please note: The pool slide and jacuzzi are NOT included as amenities in this listing and are not available for guest use. 💰 Extended stay discounts
4.79 out of 5 average rating, 70 reviews
Yellow Bench-Private Pool [No Cleaning Fee]
Your own private pool casita — no shared spaces, and no cleaning fee. Relax under open desert skies, float the afternoon away, and actually unwind. Yuma gets more sunshine than anywhere else in the country — over 300 days a year. Winters are warm and dry, summers are hot and quiet. If you're coming for spring training, to visit Mexico, river recreation, off-road events, or just to escape cold weather, you're in the right spot. Dining, shopping, and the highway are all within a few minutes.
4.96 out of 5 average rating, 326 reviews
COZY Downtown studio!
Keep it simple at this peaceful and centrally-located guest house in the historical Century Heights neighborhood. Within walking distance from restaurants, bars, nightlife, Colorado riverfront, and hiking trails. Perfect for all traveling professionals coming to Yuma. Located minutes away from the hospital (YRMC), mall, and athletic complex (the PAAC) and MCAS. Full kitchen, stocked with basics, for extended stays. Free street parking. Guest house has private outdoor sitting area.
4.98 out of 5 average rating, 41 reviews
Su Casita
Nestled in the Foothills of Yuma in a quiet neighborhood , enjoy this quaint little Casita with all the comforts of home. Decorated in a Southwest flair this little gem has everything you could want to make your stay memorable including snacks and homemade cookies. *This is a non-smoking Casita and area. There is no smoking allowed on the property. *Absolutely ONLY two people to spend the night. No smoking, no pets, no children. *Hosts have been vaccinated for Covid-19.
4.96 out of 5 average rating, 153 reviews
Quiet and Safe Southwest Bungalow
Our Southwestern-styled guesthouse is a private studio apartment complete with a kitchen and bathroom. We have a comfortable queen-sized bed. Our quiet guesthouse has great access to the interstate and is an easy five minute drive from most Yuma attractions (the Colorado river, quaint coffee shops, shopping, great restaurants, and movie theater in Old Town Yuma) The tile floor and fenced in backyard make it an ideal spot for those traveling with pets.
4.88 out of 5 average rating, 591 reviews
Private Pool for Events/Relaxing Only
Bring the whole family to swim for the day or host an event in this great venue with lots of room for fun. We can often help plan and decorate for your special occasion. Enjoy access to a stand in shower and full bathroom, kitchenette, and airconditioned suite as a rest area. Please note; linens and towels are not supplied and bed will be set up with a mattress protector, if you would like the bed made, please inquire.
5.0 out of 5 average rating, 3 reviews
Cozy Casita, Queen Bed & Covered parking
Welcome to Little Blue! Located in the Fortuna Foothills of Yuma Arizona. Whether you are staying for the night or the month, enjoy an easy relaxing stay with a queen bed, Roku TV, coffee bar, and other necessities. We take pride in the cleanliness and in providing a quality experience for every guest. The covered parking has enough room for a vehicle to remain attached to a trailer, and some additional uncovered parking!
4.95 out of 5 average rating, 159 reviews
Charmingly modern guesthouse, centrally located
Bright, fully separate guesthouse in the back of a home with a separate entrance, ideal for two. Clean, modern, and thoughtfully equipped, this space offers privacy and comfort with in-unit washer and dryer, air conditioning, and a kitchenette. Easy access to local essentials—5 minutes to Onvida Hospital and Sprouts, and just minutes from coffee shops, restaurants, and neighborhood shops.
4.97 out of 5 average rating, 236 reviews
Guesthouse in Yuma
Kick back and relax in this calm, stylish space. We are close to restaurants, shopping, MCAS and airport, located near freeway and Exceptional Community Hospital. Short drive to Los Algodones, Mexico a popular border town destination for medical/dental/pharmacy tourism where you can visit and enjoy. We are also a short drive to the Imperial sand Dunes and near by lakes.
5.0 out of 5 average rating, 25 reviews
Tiny Home Retreat – Queen Bed & Washer/Dryer A/C
The Modern Tiny Casita is located in the Foothills of Yuma, on a secured fenced lot. We have all the comforts of home. Perfect spot to rest your head at night and to watch the sun set/rise. The neighborhood is quiet, friendly and safe. The Tiny home is spacious and well thought out to meet all your needs.
4.97 out of 5 average rating, 90 reviewsPopular amenities for Yuma County guesthouse rentals
Family-friendly guest house rentals

Southwest Casita Guesthouse at Fortuna Foothills
4.79 out of 5 average rating, 61 reviews
Warm & Modern | Casa Luna w/ Patio & Kitchen
4.98 out of 5 average rating, 52 reviews
Foothills guesthouse. summer Specials!
4.75 out of 5 average rating, 4 reviews
1BR casita Close to West Wetlands, Dogs welcome!
4.89 out of 5 average rating, 9 reviews
Cozy Travel Home with Fire Pit and WI-FI
5.0 out of 5 average rating, 6 reviews
Cozy Desert Studio | Private Entrance +Kitchenette
New place to stay
La Solana at Casa Verde - Historic Downtown Yuma

1 Bedroom Guest house in a Ranch
4.68 out of 5 average rating, 382 reviewsGuest house rentals with a patio

Pool Side Casita-Yuma Foothills
5.0 out of 5 average rating, 3 reviews
Casitas in the Sweet Southwest
4.31 out of 5 average rating, 35 reviews
Hoosier Desperado Date Garden

Newly renovated, historic Studio
4.98 out of 5 average rating, 57 reviews
Desert Oasis Casita
4.98 out of 5 average rating, 53 reviews
Black Regency 2
4.62 out of 5 average rating, 164 reviews
King Bed Desert Getaway Golf Nearby Quiet Cold A/C
4.91 out of 5 average rating, 69 reviews
La Casita Yuma
4.96 out of 5 average rating, 96 reviewsGuest house rentals with a washer and dryer

Yuma Casita By Hospital
5.0 out of 5 average rating, 7 reviews
Cactus Cottage
4.87 out of 5 average rating, 39 reviews
Private suite with private bath
4.5 out of 5 average rating, 8 reviews
Unique Living Guest House
4.87 out of 5 average rating, 47 reviews
Quaint 1 bedroom private guest house
4.72 out of 5 average rating, 61 reviews
#5 Vintage Cactus House
New place to stay
Private Casita across Country Club Golf Course.
5.0 out of 5 average rating, 6 reviews
Poolhouse Retreat | Outdoor Oasis & Pets Welcome
5.0 out of 5 average rating, 12 reviewsDestinations to explore
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