Guesthouse vacation rentals near University of Arizona

4.97 out of 5 average rating, 445 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in an infrared or hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies—lounge in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

A modern living space features a comfortable black sofa and a wooden coffee table with a simple decorative tray. A dining area with a white table and four chairs is visible, alongside a kitchen equipped with dark cabinetry and appliances. Natural light enters through large glass doors leading to an outdoor space.

4.99 out of 5 average rating, 143 reviews

Casita Chapulin

Welcome to your home away from home in Tucson! Rest, relax and recharge in our peaceful, modern casita, centrally located in the Jefferson Park historic neighborhood, one mile north of the University of Arizona. Our casita features a comfy, queen-sized bed, full bath and shower, and access to the shared patio and desert garden, with hot tub, among other amenities. Whether you are here for business or leisure, we will be delighted to have you as our guest in this beautiful city we call home.

A rustic adobe exterior is adorned with a wooden door framed by natural wood accents. Prickly pear cacti grow on either side, set against a textured adobe wall. Pebbles cover the ground, complementing the earthy tones of the structure.

4.96 out of 5 average rating, 147 reviews

Adobe Carriage House downtown Chiminea+Ramada

This studio is spacious & comfortable. It is detached, secluded, on a quiet street, ample street parking and completely fenced in. The yard has a ramada with a table, chairs, string lights and a chiminea Inside, you’ll love the exposed adobe, skylight, and wood beam ceilings. The fully stocked kitchen is updated, with full size appliances. In the heart of Armory Park, it is close to 5-points, downtown, historic 4th Ave and Uof A. Ask me for dining, hiking, shopping and day trip recs!

The exterior of the guest house is showcased, featuring crisp white walls and a modern blue roof. Large windows allow natural light to illuminate the entrance, which is bordered by minimalist plants in black pots. A concrete porch extends across the front.

4.89 out of 5 average rating, 266 reviews

Newly Constructed Downtown Guesthouse

This newly constructed, spacious guest house has an open floor plan with a loft bedroom featuring the most cozy queen-sized bed. The bathroom has a soaking tub and there’s an outdoor shower too. There’s a large gated yard and three porches on which to enjoy a morning cup of coffee or tea. Located in the coveted Dunbar Spring neighborhood, the home is walking distance to the University of Arizona, 4th Ave, downtown, lots of coffee shops and restaurants and the Warehouse Arts District.

A comfortable living area is presented, featuring a brown leather sofa opposite a circular wooden coffee table. A colorful area rug adds texture to the floor, while a floor lamp and a large mirror enhance the inviting ambiance. Bright yellow curtains frame a nearby window.

4.98 out of 5 average rating, 488 reviews

The Southwest Knest

Cozy and charming, this private guest house sits in the heart of Tucson and makes a perfect home base during your visit to the Southwest! Studio layout is spacious and relaxing for 2. Fully equipped kitchen, bathroom with walk-in shower, Ghostbed mattress, and comfortable work space/fast wifi for those of you working remotely. Easy access to airport, U of A, Saguaro NP, shopping, and hiking trails. Coded entry makes it a breeze to come and go, no shared keys. Come rest at the Knest!

A modern kitchen space is visible, featuring grey cabinetry and a white countertop with a small seating area. A bar stool is placed next to a round table. Light from a window illuminates the area, with a TV mounted on the wall in the background.

5 out of 5 average rating, 102 reviews

Modern 1 bdrm Casita in Central Broadmoor Village

Start your mornings on the front porch with hummingbirds dancing through the garden, or unwind out back beneath the shade of a palo verde tree. Inside, enjoy the airy, sun-filled vibe of a modern casita with warm southwestern farmhouse style. Just a 10 min walk along the nearby bike path brings you to local favorites like Barrio Bread, and several restaurants. Located in a quiet, central Tucson neighborhood, only 5 mins from the University of Arizona and 5–10 mins from downtown.

The bright bedroom features a spacious bed with soft linens and two yellow accent pillows. Natural light fills the space through large windows, which overlook a serene outdoor area with cacti. Comfortable seating options, including armchairs and a round pouf, accompany the bed.

4.95 out of 5 average rating, 539 reviews

Central and Stylish Midcentury Pool House

Our beautiful adobe pool house is a Tucson gem. Comfortable queen bed, fireplace, and stylish modern furnishings with large windows looking out to trees and sparkling pool. Vaulted ceilings and natural light make for a restful space. Located in historic Jefferson Park, it’s a midtown oasis close to the UofA and two blocks from the UMC/Banner Medical Center. Midtown/University location allows for convenient access to all of Tucson. *Newly improved high speed WiFi 11/1/2021

A spacious studio features a queen-sized bed adorned with a soft coverlet. A curved red lounge chair complements the warm adobe walls and wooden ceiling beams. Natural light filters through large windows, illuminating the cozy corner with a beehive fireplace, enhancing the tranquil atmosphere.

4.96 out of 5 average rating, 887 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

A cozy sleeping area features a spacious bed adorned with neutral linens and decorative pillows. A brown leather chair complements the wooden bed frame, while a round mirror reflects natural light from the nearby window. Soft textiles create an inviting atmosphere.

4.95 out of 5 average rating, 173 reviews

Central Casita Minutes from UA & Downtown

Perfect for a weekend getaway or a long-term stay, our casita in midtown is fully equipped with everything you need to experience all that Tucson has to offer. 344 sq ft, this small and mighty space offers a fully-equipped kitchenette, theater-quality entertainment center, high speed wifi access, and washer and dryer access. Enjoy the spacious patio while you sip morning coffee or grill in the evening. You may find it hard to check-out of this cozy gem!

An open living space features exposed brick walls and a wooden ceiling with beams. A rocking chair and loveseat provide seating options. A kitchenette is visible, equipped with various utensils and appliances, and a small dining table sits nearby. Bright natural light enters through the window.

4.97 out of 5 average rating, 115 reviews

Studio in the Heart of the City

Casita Nopal is a bright and airy guesthouse, located in the heart of the West University Neighborhood of Tucson. It has easy access to dining, nightlife and cultural events. The guesthouse is nestled behind the main house. Guests have access to a private patio for their morning coffee or tea. You'll find all the necessary accouterments to prepare a simple meal in your own kitchen. The studio is equipped with A/C, WiFi and Smart TV.

An inviting entryway features a blue dresser with floral accents and a small yellow dinosaur figurine. Two doors lead to a bathroom and kitchen, while open shelving displays decorative items. Light-colored walls and tile flooring enhance the bright atmosphere.

4.9 out of 5 average rating, 287 reviews

Renovated Casita with Private Courtyard

Escape to your private, sparkling clean casita in the heart of Tucson! This stylish, fully renovated retreat for two features a full kitchen, a cozy queen bed, and a private courtyard with a grill and string lights. Perfectly located just 1.3 miles from the University of Arizona and a 5-minute drive to downtown, it's an ideal base for exploring the city. Enjoy the peace of a quiet neighborhood with easy access to everything.

The vibrant blue exterior of the guesthouse is softly illuminated by warm lights, highlighting the welcoming entrance. A textured stone path leads to the door, flanked by a cozy seating area with two chairs and a small table, set amid the serene outdoor landscape.