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Apartment vacation rentals in Santiago Metropolitan Region

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santiago Metropolitan Region

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Superhost
Apartment in Santiago
5.0 out of 5 average rating, 4 reviews

Londres 50 - Suite Deluxe 201

This Suite stands out for its heritage elegance and contemporary design. With high ceilings, an ornamental fireplace and a French balcony overlooking the classic architecture of the Paris-London neighborhood, this space invites you to live a boutique experience. Equipped with a king-size bed, designer sofa, dining area and fully equipped kitchen, it combines functionality with style. It is ideal for those looking for an exclusive environment with history, perfect for stays in the heart of the city's cultural center.

Top guest favorite
A spacious bedroom features a comfortable bed adorned with a light green throw and neatly arranged towels. Natural light enters through large windows, illuminating a cozy seating area with a chair and small table. Two bedside lamps add subtle lighting to the room.
Apartment in Santiago
4.99 out of 5 average rating, 102 reviews

Prime apt w/fast wifi-AC-Long stay clean-Lastarria

Relax in this modern, renovated apartment, fully equipped for a perfect stay. Enjoy: - Split-system inverter air conditioning - High-speed Wi-Fi - Washer/dryer - Hair dryer and straightener - Bed with soft cotton sheets - Nespresso coffee maker - Secure building with 24/7 concierge - Located in the heart of the Lastarria neighborhood, just steps away from Santiago's best restaurants, cafes, museums, and attractions. Feel free to message me with any questions—I’d be happy to help.

Guest favorite
Apartment in Santiago
5.0 out of 5 average rating, 13 reviews

Japandi in downtown Santiago | Jacuzzi | Wi-Fi

⛩️ Takamitama (たかみたま) is an urban retreat inspired by Japanese aesthetics, ideal for those seeking to disconnect without leaving the heart of Santiago. 💎 Its name can be interpreted as “the jewel in the heights,” reflecting a space where tranquility, design, and well-being come together above the city. 📍 Located in downtown Santiago, just a 7-minute walk from the Santa Lucía Metro, it offers a unique experience of rest and relaxation in the middle of the urban environment.

Guest favorite
Apartment in Las Condes
4.93 out of 5 average rating, 700 reviews

AT HOME El Golf Apartment 3 rooms

Wake up in the exclusive El Golf district. Spacious, bright, and fully equipped apartments. Featuring three bedrooms (master en-suite), an open-plan living and dining area, a fully equipped kitchen, and a separate lounge ideal for a home office. Enjoy fully autonomous access, high-speed WiFi, and impeccable cleaning standards. Located just steps from the Metro, and surrounded by top restaurants, cafés, parks, and everything you need to move around Santiago with ease.

Top guest favorite
A cozy living area features a dark sofa adorned with yellow cushions, complemented by a vibrant wall painting depicting a coastal scene. A glass coffee table sits atop a patterned rug, while a small dining table with wooden chairs is situated nearby, creating a welcoming space.
Apartment in Santiago
4.99 out of 5 average rating, 209 reviews

2 Bedrooms Parque Forestal, Downtown Santiago

Relax in a comfortable and spacious apartment located on the eighth floor of a high-end building, in Santiago's most elegant neighborhood, surrounded by luxury hotels and steps away from the Museum of Fine Arts and the forest park. A completely clear view towards Santa Lucía Hill and Lastarría and Bellas Artes neighborhoods from your balcony. Fully equipped with everything you need and high quality to spend a perfect and comfortable family stay in this peaceful place.

Top guest favorite
A contemporary living space is shown, featuring a plush sofa in front of a coffee table. Bookshelves filled with various items create an organized backdrop. A dining table with chairs is visible, along with two bar stools at the kitchen counter. Natural light fills the room through large windows.
Apartment in Santiago
4.93 out of 5 average rating, 137 reviews

Lastarria neighborhood | View of Cerro Santa Lucia

Furnished apartment, equipped kitchen, bathroom with washer/dryer, master bedroom with TV, living room with sofa bed, dining room, WiFi, secure building with concierge and closed circuit. Located in the Lastarria neighborhood, in front of Santa Lucia Hill, steps away from the metro and the Fine Arts Museum. In an eminently tourist area, in the middle of the city's historic center, surrounded by parks, restaurants, museums, shopping center and many areas of interest.

Top guest favorite
A comfortable sleeping area is showcased, featuring a spacious bed adorned with neutral-colored bedding. Two bedside lamps provide soft lighting, while potted plants enhance the natural feel of the room. A stylish area rug lies beneath the bed, complementing the warm wood tones of the floor.
Apartment in Santiago
4.99 out of 5 average rating, 161 reviews

Welcome to Santiago/metro Toesca

Enjoy the comfort that Welcome to Santiago! has prepared for you. Get to know the city's iconic places. We are 5 minutes from the TOESCA metro station, 15 minutes from the Movistar Arena, 10 minutes from the Fantasilandia amusement park and steps from the O'Higgins park. We have everything you need to make your stay as comfortable as possible, fully equipped kitchen, bathroom and living-dining room. Attention!! The pool season starts on November 24, 2025

Guest favorite
Apartment in Santiago
4.97 out of 5 average rating, 35 reviews

Urban Jungle Loft

A fully equipped urban loft with a unique design facing Plaza Brasil, steps from the historic Concha y Toro neighborhood, and two blocks from the Cumming metro. A warm and sophisticated retreat steps from the historic center of Santiago, designed to provide comfort, tranquility and a welcoming energy. Its warm lights, natural textures, and relaxing atmosphere make it the perfect place to rest, disconnect, and enjoy the city in style.

Guest favorite
An open-plan kitchen and dining area is visible, featuring a wooden dining table surrounded by green and wire-framed chairs. The modern kitchen includes light cabinetry and stainless steel appliances. A potted plant adds a touch of greenery to the space, enhancing its bright ambiance.
Apartment in Santiago
4.92 out of 5 average rating, 106 reviews

Apartment in Barrio Lastarria

Beautiful and bright newly remodeled apartment located in Barrio Lastarria, a bohemian place full of culture, art and food. The location is ideal for discovering Santiago. It is just a 5-minute walk to the nearest metro station, close to the city's historic center, at the foot of Santa Lucía Hill, and close to parks and museums. Enjoy our cozy and modern apartment with an attractive design fully equipped for vacation or work.

Top guest favorite
Apartment in Valparaíso
5.0 out of 5 average rating, 142 reviews

Puerto Claro 2 - Location- View- Spacious- Design

Hello! We invite you to explore this spacious and bright apartment in the heart of Cerro Concepción, lovingly renovated for you. The apartment is on the third floor, so you’ll need to climb some stairs. But we promise it’s worth the effort when you enjoy the amazing views from the terrace and the over 90 square meters waiting for you. Thanks to its great location, you can easily visit the main attractions of the port.

Guest favorite
Apartment in Ñuñoa
5.0 out of 5 average rating, 20 reviews

31st Floor | Costanera View | Metro Steps

Modern apartment on the 31st floor with panoramic views of Santiago and the Andes, located right across from Irarrázaval Metro Station for easy access to the entire city. The apartment features a comfortable bedroom, bright living room with balcony views, a fully equipped kitchen, and a sofa bed for up to 3 guests. Perfect for couples, business travelers, or small families looking to enjoy Santiago from above.

Top guest favorite
A bright and modern living space features a light wooden shelf adorned with decorative items and plants. A comfortable sofa with neutral cushions complements the inviting atmosphere. A well-lit kitchen island is set with dishes and glassware, offering a functional yet stylish ambiance.
Apartment in Santiago
4.97 out of 5 average rating, 36 reviews

Luxury & Design | Palace & Park Views

Cozy and elegant apartment in the heart of Lastarria, one of the most cultural and vibrant neighborhoods in Santiago. Decorated in a warm and modern style, it has a double bed, a fully equipped kitchen, a desk for teleworking and well-lit spaces. Within walking distance of museums, parks, cafes, restaurants and metro stations. Ideal for relaxing, exploring the city, and living like a local.

Popular amenities for Santiago Metropolitan Region apartment rentals

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