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Apartment vacation rentals in Santiago Metropolitan Region

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santiago Metropolitan Region

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Guest favorite
Apartment in Santiago
4.95 out of 5 average rating, 22 reviews

Londres 50 - Suite Deluxe 204

A heritage suite that combines history and modernity. It features high ceilings, French windows and an original ornamental fireplace. Its design combines classic charm with minimalist style, creating a sophisticated and cozy atmosphere in the heart of the Paris-London neighborhood. Equipped with a king-size bed, designer sofa, dining room, full kitchen, air conditioning, high-speed Wi-Fi, and private bathroom. Accommodating up to 3 people, it is ideal for couples or travelers who value comfort and style.

LocationGetting aroundQuiet

Top guest favorite
A spacious bedroom features a comfortable bed adorned with a light green throw and neatly arranged towels. Natural light enters through large windows, illuminating a cozy seating area with a chair and small table. Two bedside lamps add subtle lighting to the room.
Apartment in Santiago
4.99 out of 5 average rating, 102 reviews

Prime apt w/fast wifi-AC-Long stay clean-Lastarria

Relax in this modern, renovated apartment, fully equipped for a perfect stay. Enjoy: - Split-system inverter air conditioning - High-speed Wi-Fi - Washer/dryer - Hair dryer and straightener - Bed with soft cotton sheets - Nespresso coffee maker - Secure building with 24/7 concierge - Located in the heart of the Lastarria neighborhood, just steps away from Santiago's best restaurants, cafes, museums, and attractions. Feel free to message me with any questions—I’d be happy to help.

LocationFamilyParks

Guest favorite
Apartment in Las Condes
4.93 out of 5 average rating, 695 reviews

AT HOME El Golf Apartment 3 rooms

Wake up in the exclusive El Golf district. Spacious, bright, and fully equipped apartments. Featuring three bedrooms (master en-suite), an open-plan living and dining area, a fully equipped kitchen, and a separate lounge ideal for a home office. Enjoy fully autonomous access, high-speed WiFi, and impeccable cleaning standards. Located just steps from the Metro, and surrounded by top restaurants, cafés, parks, and everything you need to move around Santiago with ease.

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Top guest favorite
A cozy living area features a dark sofa adorned with yellow cushions, complemented by a vibrant wall painting depicting a coastal scene. A glass coffee table sits atop a patterned rug, while a small dining table with wooden chairs is situated nearby, creating a welcoming space.
Apartment in Santiago
4.99 out of 5 average rating, 207 reviews

2 Bedrooms Parque Forestal, Downtown Santiago

Relax in a comfortable and spacious apartment located on the eighth floor of a high-end building, in Santiago's most elegant neighborhood, surrounded by luxury hotels and steps away from the Museum of Fine Arts and the forest park. A completely clear view towards Santa Lucía Hill and Lastarría and Bellas Artes neighborhoods from your balcony. Fully equipped with everything you need and high quality to spend a perfect and comfortable family stay in this peaceful place.

FamilyValueComfort

Guest favorite
A spacious bedroom features a comfortable bed with plush pillows, accented by decorative wall art made of natural materials. A wooden ladder stands against the wall, and bedside tables with lamps are positioned on either side of the bed, enhancing the room's cozy atmosphere.
Apartment in Santiago
4.95 out of 5 average rating, 169 reviews

Modern Apt. Subway Sta. Lucia 1 bedroom + 1 bath

Comfortable and cozy accommodation New and modern building steps away from Santa Lucia metro station so you can get around wherever you want. The perfect place to feel right at home. Where you can enjoy a comfortable king-size bed! A coffee maker for coffee lovers, a bottle of purified water, and some cold beers to help you relax. Everything designed for you to have a pleasant stay! I'm Francisca and I'm available 24/7! I look forward to having you stay with us

ValueFamilyBiking

Top guest favorite
A comfortable sleeping area is showcased, featuring a spacious bed adorned with neutral-colored bedding. Two bedside lamps provide soft lighting, while potted plants enhance the natural feel of the room. A stylish area rug lies beneath the bed, complementing the warm wood tones of the floor.
Apartment in Santiago
4.99 out of 5 average rating, 158 reviews

Welcome to Santiago/metro Toesca

Enjoy the comfort that Welcome to Santiago! has prepared for you. Get to know the city's iconic places. We are 5 minutes from the TOESCA metro station, 15 minutes from the Movistar Arena, 10 minutes from the Fantasilandia amusement park and steps from the O'Higgins park. We have everything you need to make your stay as comfortable as possible, fully equipped kitchen, bathroom and living-dining room. Attention!! The pool season starts on November 24, 2025

FamilyLocationCleanliness

Top guest favorite
A living space is shown, featuring a comfortable sofa adorned with colorful pillows. A stone countertop contrasts against the backdrop of a large window, showcasing a panoramic view of the surrounding landscape, including a nearby mountain. Decorative elements add a stylish touch.
Apartment in Ñuñoa
4.96 out of 5 average rating, 244 reviews

25th floor, A/C & Wifi, parking available upon request

🌟 @Royalregalchile We invite you to enjoy this incredible 1-bedroom apartment 🛌 and 1 bathroom 🚿 with air conditioning ❄️, fast wifi 📶, impeccable cleaning ✨. Located in the heart of Ñuñoa, steps from the vibrant Barrio Italia 🌿, full of cafes☕, shops🛍️ and restaurants🍽️. Unbeatable service, and our guests' feedback is proof. Close to the Irarrázaval Metro 🚇 (L3 and L5). Book now and live the best experience! Private parking 🅿️ ($5,000 daily)

LocationValueView

Guest favorite
Apartment in Santiago
4.94 out of 5 average rating, 110 reviews

Paris-Londres - Quiet, bright & prime location

✨ Bright, silent and cozy studio in the charming Paris-Londres district, one of Santiago’s most beautiful and walkable areas. A quiet, comfortable and fully equipped space with a peaceful inner courtyard view, perfect to unwind from the city. Ideal for relaxing, remote work or exploring on foot. 📍 Steps from metro, Santa Lucía Hill, La Moneda, cafés and restaurants. Fits 1–3 guests, with fast WiFi, Smart TV, equipped kitchen and self check-in.

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Guest favorite
Apartment in Ñuñoa
5.0 out of 5 average rating, 7 reviews

A/C, exclusive, centrally located and secure, mountain view

Welcome to Santiago de Chile 🇨🇱! Enjoy a comfortable stay in this modern 1-BD, 1-BA apartment, located on the 18th floor with an unobstructed view of the Andes Mountains, equipped with double-glazed windows, a fully electric kitchen with a glass-ceramic countertop, oven, hood and quartz stone countertop. Only a 4-minute walk 🚶🏻‍♂️🚶🏼‍♀️to the Irarrazaval metro 🚇. You will have very easy access to explore the city and its surroundings.

LocationSleep qualityGetting around

Guest favorite
An open-plan kitchen and dining area is visible, featuring a wooden dining table surrounded by green and wire-framed chairs. The modern kitchen includes light cabinetry and stainless steel appliances. A potted plant adds a touch of greenery to the space, enhancing its bright ambiance.
Apartment in Santiago
4.92 out of 5 average rating, 106 reviews

Apartment in Barrio Lastarria

Beautiful and bright newly remodeled apartment located in Barrio Lastarria, a bohemian place full of culture, art and food. The location is ideal for discovering Santiago. It is just a 5-minute walk to the nearest metro station, close to the city's historic center, at the foot of Santa Lucía Hill, and close to parks and museums. Enjoy our cozy and modern apartment with an attractive design fully equipped for vacation or work.

ValueLocationGetting around

Top guest favorite
Apartment in Centro Histórico
4.99 out of 5 average rating, 117 reviews

Downtown, subway 3 blocks away. 24/7 self check-in. A/C

Comfortable and centrally located apartment in Santiago, perfect for short and long stays. Guests highlight: "Impeccable cleanliness and everything tidy," "very quiet and close to everything," "it feels like home." It has A/C, 24/7 self check-in and an equipped kitchen. A 5-minute walk from Plaza de Armas, the Metro, Moneda and shops. Includes swimming pool and green areas. You arrive and everything is ready for you to rest.

FamilyValueIndoor spaces

Top guest favorite
Apartment in Valparaíso
5.0 out of 5 average rating, 141 reviews

Puerto Claro 2 - Location- View- Spacious- Design

Hello! We invite you to explore this spacious and bright apartment in the heart of Cerro Concepción, lovingly renovated for you. The apartment is on the third floor, so you’ll need to climb some stairs. But we promise it’s worth the effort when you enjoy the amazing views from the terrace and the over 90 square meters waiting for you. Thanks to its great location, you can easily visit the main attractions of the port.

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