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Vacation rentals in Santa Cruz Tlaxcala

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz Tlaxcala

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Home in Santa Ursula Zimatepec
4.92 out of 5 average rating, 26 reviews

Casa Lozada – Spacious and beautiful home in Apizaco

Enjoy a comfortable, spacious and cozy home in Santa Ursula that will make you feel at home. It has 3 bedrooms, 2.5 bathrooms, equipped kitchen, terrace and garage for 2 cars. Strategic location: 10 minutes from the high-performance sports center, 10 minutes from downtown Apizaco, 20 minutes from Tlaxcala capital, 30 minutes from Huamantla and 25 minutes from the industrial corridor With easy access to transportation, supermarkets and schools. Ideal for relaxing and sharing unforgettable moments with family or friends

Guest favorite
The exterior entrance features a pathway bordered by greenery, leading to a modern façade with large windows. Plants are positioned for visual interest beside the pathway, while soft evening light enhances the welcoming appearance of the entrance.
Home in Apizaco
4.88 out of 5 average rating, 68 reviews

Complete House with 2 Bedrooms, Garden and Barbecue

Enjoy a comfortable and pleasant stay in this house with functional design and good taste. Perfect for families, couples or travelers, our house has everything you need to feel at home; comfortable rooms and hot water 24/7. Whether you are coming for work, tourism or visiting, you will find comfort and tranquility. 3 minutes from Chedraui, FEMSA, UATX, 7 minutes from the Apizaco Center, 8 from the Regional Hospital, 12 minutes from Ciudad Judicial, 20 from CIX I, and 30 minutes from La Malinche.

Guest favorite
A spacious two-story house features a warm exterior and large glass doors that connect the indoor and outdoor areas. In the foreground, a patio set with six chairs surrounds a glass table, situated on a green lawn that extends to the house.
Home in Santa María Atlihuetzia
4.88 out of 5 average rating, 24 reviews

Beautiful house with a large garden

Less than two hours from Mexico City, spacious and cozy house very well lit with large garden, ideal for resting in a peaceful place, meeting and living with family or friends, appreciate the majesty of the Malinche, have breakfast or roast a meat outdoors, even play volleyball or basketball, or relax in the jacuzzi. Strategically located 20 minutes from downtown Tlaxcala and less than an hour from tourist attractions such as El Santuario de las Luciérnagas and Val'Quirico.

Top guest favorite
Apartment in Val'Quirico
4.97 out of 5 average rating, 37 reviews

Experience staying in Val'Quirico

Our loft offers a unique stay, surrounded by magic, architectural charm and a European atmosphere. Wake up to beautiful views, enjoy walking through its cobbled streets, restaurants, cafes, bars and boutiques… all just a few steps away! Ideal for romantic getaways, couples trips, rest or total disconnection. A comfortable, clean, and carefully prepared space for you to enjoy every moment. Stay in the heart of Val'Quirico and create unforgettable memories

Guest favorite
A spacious sleeping area features a wooden four-poster bed with soft gray bedding. Natural light fills the room through large windows, framed by minimalistic light fixtures. A small table and chair are positioned beside the window, offering a serene view of the surrounding greenery.
Loft in Santa Agueda
4.98 out of 5 average rating, 139 reviews

Exclusive Penthouse, Val`Quirico

Perfect romantic escape for couples or solo travellers looking to unwind and relax. The private penthouse apartment is just a five minute walk away from the heart of Val’Quirico, includes free parking and a fully equipped kitchen. The private terrace is perfect for romantic dinners, star gazing and has amazing views of the Malinche mountain where the sunrises. An ideal space to recharge, celebrate love and enjoy an unforgettable experience.

Top guest favorite
Apartment in Apizaco
4.98 out of 5 average rating, 50 reviews

A complete and centrally located apartment

Excellent full apartment with privileged location in Apizaco Tlax. Ideal for short and long stays, located on the second floor of a building, in front of the only Soriana in the center, 5 minutes from the city's main park and with a fast route to the main roads. It has two full bedrooms, a full kitchen, a full bathroom and a living room with all amenities. Free street parking or a boarding service a block and a half away at no extra cost.

Guest favorite
Cottage in Santa Cruz Tlaxcala
4.92 out of 5 average rating, 39 reviews

Spectacular Ranch 5 minutes from Trinidad IMSS

Bring the whole family to this fantastic place, enjoy the tranquility of nature, without leaving aside the fun both outside and inside, with the bar, pool table or movie night! Relax at this ranch located in the municipality of Santa Cruz Tlaxcala. Enjoy the views from the hillside, walk around the property, or visit the La Trinidad Holiday Center. At night, immerse yourself in the incredible views of the galaxy in the open field.

Superhost
A modern two-story house is visible, featuring large windows and a spacious roof terrace. The exterior is characterized by a combination of white and dark gray materials. A paved driveway leads to the entrance, with well-maintained grass beside it, under a partly cloudy sky.
Home in San Buenaventura Atempan
4.77 out of 5 average rating, 90 reviews

House with a view: 11 people, WiFi, Invoice

Spacious and amazing views! 🏔️ Stay in this complete Residential House for 11 people. 🚗 Private Garage: Closed and secure parking for 4 cars. 🚿 No lines: 3.5 bathrooms and 4 spacious bedrooms for everyone to get ready comfortably. 📍 Premium Location: Walk to Plaza Vértice (Cinema/Walmart/Restaurants) and Tlahuicole Stadium. Includes fast WiFi, full kitchen, view of La Malinche and check-in. Book the best space in Tlaxcala!

Guest favorite
A decorative stone fountain features a multi-tiered design, with flowing water cascading down. Surrounding the fountain are vibrant red poinsettias in black planters, creating a welcoming focal point in the outdoor space.
Home in Apizaco Centro
4.94 out of 5 average rating, 213 reviews

AMAZING "CASA CARMELA" in the center of Apizaco

THIS SPACE FOLLOWS AIRBNB'S ADVANCED CLEANING PROTOCOL. Cozy and wonderful 1-story house, located in downtown Apizaco. Excellent location a few blocks from restaurants, bars, convenience stores, cinema, among others. The house has excellent essential services (Internet, Netflix), as well as a garage (5.0 meters long) for a small or medium-sized sedan or SUV. We accept small or medium-sized pets; large pets with prior approval.

Guest favorite
Home in Ocotlán
5 out of 5 average rating, 17 reviews

Luka House. Cozy and private near downtown.

Enjoy a comfortable and quiet stay in this private 1-bedroom house, ideal for couples. Just 8 minutes from downtown, it combines privacy and a good location. You will feel at home, it has a large garden where you can meditate and take a break. Perfect for resting The space •1 bedroom •Entire house •Kitchen area •Large garden •Parking Location •8 minutes from downtown Tlaxcala • Quiet and safe area

Guest favorite
The kitchen features warm, earthy tones with rich wooden cabinets and a tiled backsplash. Ample counter space includes a microwave and coffee maker. A gas stove and sink are positioned beneath the window, allowing natural light to enhance the inviting space.
Apartment in San Miguel Contla
4.8 out of 5 average rating, 50 reviews

Comfortable apartment with an excellent view

Cozy, quiet and luxurious apartment, ideal for family and friends who come to visit "located 3 minutes from the Trinidad Vacation Center, 5 minutes from Apizaco Centro, 15 minutes at the foot of Volcán la Malinche and 20 minutes from Huamantla" Excellent view and location ! Don't think about it and take advantage of your stay !

Guest favorite
Home in Santa María Atlihuetzian
5 out of 5 average rating, 13 reviews

Malintzi Garden House | Pet Friendly. We invoice

This beautiful accommodation is ideal for weekends with family, friends or as a couple, large garden with barbecue for gatherings and children's games, everyone will enjoy the beautiful view of the Malintzi, in addition to all the comforts of a charming, relaxing place full of harmony with nature.

Popular amenities for Santa Cruz Tlaxcala vacation rentals

  1. Airbnb
  2. Mexico
  3. Tlaxcala
  4. Santa Cruz Tlaxcala