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Vacation rentals in Santa Cruz Tlaxcala

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz Tlaxcala

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
The exterior entrance features a pathway bordered by greenery, leading to a modern façade with large windows. Plants are positioned for visual interest beside the pathway, while soft evening light enhances the welcoming appearance of the entrance.
Home in Apizaco
4.87 out of 5 average rating, 38 reviews

Complete house with 2 bedrooms, garden and barbecue

Enjoy a comfortable and pleasant stay in this house with functional design and good taste. Perfect for families, couples or travelers, our house has everything you need to feel like home; comfortable rooms and hot water 24/7. Whether you are coming for work, tourism or visiting, you will find comfort and peace of mind. 3 minutes from Chedraui, FEMSA, UATX, 7 minutes from Centro de Apizaco, 8 from the Regional Hospital, 12 minutes from Ciudad Judicial, 20 from CIX I, and 30 minutes from La Malinche.

Guest favorite
A dining area is presented with a wooden table set for six, featuring glassware and plates. The space is illuminated by natural light from nearby windows, with a view into the kitchen area visible through an archway. Decorative elements and potted plants add to the ambiance.
Home in El Sabinal
4.96 out of 5 average rating, 102 reviews

"Casa Estela" is impeccable and comfortable.

Enjoy this beautiful house detailed in wood, well lit, ideal for 1 to 6 people, in a quiet and family area. Ground floor: garage for one car, living room, dining room, bar, full bathroom, equipped kitchen, patio with barbecue. Upper floor: master bedroom with 1 double bed, 1 comfortable sofa bed, 2 large closets, full bathroom, second bedroom with 1 double bed and spacious closet, plus a study for working. Just 15 minutes from downtown Tlaxcala and 5 minutes from a shopping mall.

Top guest favorite
The exterior of the house showcases a two-story design with a combination of brick and stucco surfaces. Large, arched windows are framed in black, accentuated by decorative balconies on both levels. A grassy area and trees provide greenery, with a bright blue sky overhead.
Home in Tlaxcala
4.94 out of 5 average rating, 127 reviews

BEAUTIFUL ADOBE HOUSE IN TLAXCALA

Beautiful cottage with excellent accommodation conditions. Wonderful location. Near the best tourist spots in the area: -Zócalo de Tlaxcala and Government Palace with its spectacular murals -Plaza de Toros, one of the most beautiful in the country -Exconvent San Francisco, with its iconic bell tower and first baptismal stone - Archaeological Zone of Cacaxtla -Val´Quirico (European-flavored village) 45 km from the magical town of Huamantla and 25 minutes from Puebla City.

Guest favorite
Loft in La Loma Xicohténcatl
4.87 out of 5 average rating, 111 reviews

Private loft/near the bus station

Private loft with bathroom and private entrance. One block from the bus station, 10 minutes from downtown on foot, 2 minutes from the stairs and with super easy access to transportation just outside the room. *It is a busy street and there may be noise by transit vehicles. *We do not have private parking, but you can leave your vehicle in front of the Airbnb on the street. If you have any questions, you can send us a message and we will gladly resolve them.

Guest favorite
A kitchen area is visible, featuring wooden cabinetry and a stainless-steel refrigerator. An elegant gas stove stands beside a sink, while pendant lights illuminate the space. A blender and kettle occupy the countertop, and a cozy seating area is seen in the background.
Home in Tlaxcala Centro
4.94 out of 5 average rating, 186 reviews

Casa Jacaranda (Tlaxcala Centro)

Beautiful private and cozy house in the heart of Tlaxcala, located in the downtown area and a few steps from Xicohténcatl Park, Plaza de Toros and Zócalo. Well lit and with vehicle access and a parking space. Quiet and comfortable with all amenities, perfect for enjoying the most emblematic places of the city (former convent of San Francisco, bullring, portals, Zócalo and shops with typical and handicraft products) without having to travel by vehicle.

Guest favorite
A well-maintained garden area features lush green grass and a tree providing shade. A rustic wooden table and benches are positioned beside a stone pathway. A secure fence with barbed wire surrounds the space, ensuring privacy and safety.
Home in Apizaco
4.9 out of 5 average rating, 143 reviews

Welcome to Casa Rubí: Your refuge in Apizaco

Ideal house for families and work stays (invoice available), Wi-Fi internet and cable TV, CCTV for your security, Netflix, with basic kitchen utensils, 2 car garage (2.50m height), large garden with barbecue, new 19kg washing machine, don't miss it and bring your pet (pet friendly), beautiful fully equipped kitchen. We are distinguished by our constant continuous improvement. 20 minutes from Xicotencatl Industrial Corridor, 25 minutes from Tlaxcala.

Guest favorite
Cottage in Santa Cruz Tlaxcala
4.89 out of 5 average rating, 28 reviews

Spectacular Ranch 5 minutes from Trinidad IMSS

Bring the whole family to this fantastic place, enjoy the tranquility of nature, without leaving aside the fun both outside and inside, with the bar, pool table or movie night! Relax at this ranch located in the municipality of Santa Cruz Tlaxcala. Enjoy the views from the hillside, walk around the property, or visit the La Trinidad Holiday Center. At night, immerse yourself in the incredible views of the galaxy in the open field.

Top guest favorite
A bright living area is showcased with large windows covered by sheer curtains, allowing natural light to fill the space. A circular marble coffee table sits atop a soft area rug, accompanied by two chocolate brown armchairs and a dark sectional sofa. A television is positioned on a wooden stand.
Apartment in Apizaco
5 out of 5 average rating, 24 reviews

A complete and centrally located apartment

Excellent complete apartment with a privileged location in Apizaco Tlax. Ideal for short and long stays, located on the second floor of a building, in front of the only Soriana in the center, 5 minutes from the city's main park and with a quick route to the main roads. It has two full bedrooms, a kitchenette, a full bathroom, and a living room with all amenities. Free street parking or a parking service a block and a half away.

Guest favorite
A decorative stone fountain features a multi-tiered design, with flowing water cascading down. Surrounding the fountain are vibrant red poinsettias in black planters, creating a welcoming focal point in the outdoor space.
Home in Apizaco Centro
4.94 out of 5 average rating, 193 reviews

AMAZING "CASA CARMELA" in the center of Apizaco

THIS SPACE FOLLOWS AIRBNB'S ADVANCED CLEANING PROTOCOL. Cozy and wonderful 1-story house, located in downtown Apizaco. Excellent location a few blocks from restaurants, bars, convenience stores, cinema, among others. The house has excellent essential services (Internet, Netflix), as well as a garage (5.0 meters long) for a small or medium-sized sedan or SUV. We accept small or medium-sized pets; large pets with prior approval.

Guest favorite
A living area features comfortable black sofas arranged around a coffee table. Natural light fills the space, highlighting the minimalist decor. A doorway leads to a kitchen area, with cabinetry and an organized layout visible in the background.
Apartment in San Miguel Contla
4.8 out of 5 average rating, 45 reviews

Comfortable apartment with an excellent view

Cozy, quiet and luxurious apartment, ideal for family and friends who come to visit "located 3 minutes from the Trinidad Vacation Center, 5 minutes from Apizaco Centro, 15 minutes at the foot of Volcán la Malinche and 20 minutes from Huamantla" Excellent view and location ! Don't think about it and take advantage of your stay !

Superhost
Home in Santa María Atlihuetzian
5 out of 5 average rating, 3 reviews

“Malintzi Garden House”

Este elegante alojamiento es ideal para viajes en grupo o familiares, en el que disfrutarás de un hermoso jardín con vista a la Malintzi, además de todas las comodidades de un lugar encantador, relajante lleno de armonía con la naturaleza.

Guest favorite
A modern kitchen is displayed with a sleek design, featuring a granite countertop and chrome bar stools. Stainless steel appliances are positioned along the wall, including a refrigerator and a microwave. Soft lighting is provided by pendant lights above the countertop.
Home in Loma Bonita
4.89 out of 5 average rating, 118 reviews

Dyg Loma Bonita

Enjoy this charming home located in the picturesque Loma Bonita neighborhood. This place is perfect for travelers looking for comfort and convenience. Designed for a full family Relax in this home where tranquility is breathed.

Popular amenities for Santa Cruz Tlaxcala vacation rentals

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  4. Santa Cruz Tlaxcala