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Vacation rentals in Santa Cruz

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
The charming brick exterior of the cabin is framed by colorful plants and decorations. A decorative wheel adds character to the entrance, which features a wooden door and wrought iron accents. Bright flowers enhance the inviting atmosphere of this tranquil retreat.
Hut in Mexico City
4.6 out of 5 average rating, 106 reviews

Cozy cabin with fireplace, Quinta Josefina

Cozy and romantic cabin with fireplace in the woods, amazing panoramas of the mountains. Enjoy under the stars in the picturesque village of the magical village of the Mole; San Pedro Atocpan, hike its cobblestone streets, churches, cafes and variety of restaurants. * Contactless entrance * Queen size bed, bathroom, living room, fireplace, kitchen, balcony, terrace, terrace, barbecue. Event garden, orchard, camping area, bar, stone oven, living room with men's and women's bathrooms, parking.

Guest favorite
A sunlit living area features a mix of comfortable seating, with two wicker chairs and a wooden sofa. A glass coffee table sits at the center, surrounded by large windows offering views of the garden. Lush vegetation and flowering plants are visible outside.
Cabin in Mexico City
4.88 out of 5 average rating, 26 reviews

Cabin with garden and kitchen near chinampas

Escape to a 1,080 ft² cabin retreat nestled in Xochimilco’s UNESCO-protected chinampa zone. Bask in serenity with a 4,310 ft² private garden, inside free parking, and optional lake access. Inside, free parking, plush linens, a fan, complimentary tea, high-speed Wi-Fi, etc., await you—while modern security cameras ensure peace of mind. Stroll one minute to the Olympic track or lagoon, and 20 minutes to Xochimilco Centro. Unplug under a canopy of stars in this elegant, eco-friendly sanctuary.

Guest favorite
A modern open-concept living space is presented, featuring large glass doors that connect to a serene outdoor area. The kitchen, adorned with wooden accents, leads to a cozy seating area. Lush greenery surrounds a small plunge pool, enhancing the tranquil atmosphere.
Tiny home in Los Ocotes
4.92 out of 5 average rating, 172 reviews

Ixaya: A Luxury Loft in Tepoztlán

Welcome to Ixaya, an exclusive loft surrounded by nature and luxury. Relax on the king-size bed, the heated jacuzzi (extra cost), or the spacious sofa. Enjoy an equipped kitchen, two private gardens, and green views from any point of the loft. Just 12 minutes from downtown by car, explore local culture and food. Plus, live unique experiences like massages, yin yoga, and cacao ceremonies without leaving the Loft, or Temazcal or nearby food immersion (extra cost).

Superhost
A spacious living area features large windows that provide abundant natural light and stunning city views. A comfortable sofa is positioned near a coffee table, with a TV unit against the wall. A staircase leads to the upper level, enhancing the open layout.
Condo in Los Alpes
4.94 out of 5 average rating, 139 reviews

Spectacular PH with Christmas and New Year amenities

Get ready to appreciate the city from an exclusive PH on the 32nd floor. Whether for pleasure or business, take advantage of the amenities this space has to offer. Exercise in the gym and then work for a while in the business center, have a snack in the restaurant, relax with a massage in the SPA and enjoy an incredible view in the terrace pool, without leaving your space! Near the building, you will find main roads and a shopping plaza for your shopping. Welcome!

Guest favorite
A spacious bedroom incorporates natural elements with wood accents and soft, neutral tones. Large sliding doors lead to a comfortable living area, showcasing a cozy seating arrangement. A stylish glass shower is visible, complementing the overall modern yet serene ambiance.
Loft in Tlacopac
4.92 out of 5 average rating, 462 reviews

Entire apartment, Japanese style in San Angel.

House with one bedroom, with a beautiful Japanese garden. Exclusively for couples or people looking to rest (not a location for events, videos, or thirst for photographs) Ground floor industrial style, first and second level Japanese design. Brand new, fully equipped, with luxury finishes. The place is completely for you. We have parking outside the accommodation (street). A unique experience in the heart of San Angel. Three blocks from San Angelin Restaurant.

Top guest favorite
A minimalist sleeping area features a single bed dressed with a light-colored duvet and a yellow accent pillow. A small desk and chair are positioned nearby, complemented by a shelf with storage options. A framed artwork adds a touch of color to the wall, illuminated by soft lighting.
Loft in Moctezuma
4.97 out of 5 average rating, 395 reviews

Miniloft 10: CDMX Airport, GNP Stadium, TAPO.

Enjoy this practical and comfortable loft 10 minutes from Mexico City Airport, GNP/Autodromo Stadium, Palacio de los Deportes, TAPO Bus Terminal, Oceania/IkEA Shopping Center with cafes, bars, restaurants, cinemas, and shops. The loft is located on the second level, with a single bed, equipped kitchen, ROKU TV, desk, safe, Wi-Fi, and a private bathroom. The building has a shared washing machine and roof garden. There is a park in front of the building.

Top guest favorite
An aerial view of the spacious living area showcases natural lighting illuminating the marble flooring. A large dining table with dark, textured placemats is positioned near the wooden beams. A comfortable seating arrangement is visible on the other side, creating an inviting environment.
Home in Magisterial Vista Bella
4.98 out of 5 average rating, 174 reviews

The Rainforest Chalet

Hermosa casa, diferente a todo lo que puedas encontrar en la zona, las fotos hablan por si solas, con una ubicación sumamente céntrica, servicios de comida, hospitales, restaurantes, centros comerciales importantes como lo son Mundo E y Plaza Satélite a 5-10 minutos en auto, transporte publico en la esquina el cual te lleva directamente al metro Cuatro Caminos, a 20 minutos de CDMX, 7 de Periférico y 15 de la carretera para Santa Fe, Interlomas.

Top guest favorite
Apartment in Amecameca
4.94 out of 5 average rating, 17 reviews

Wulkan Studio+Breakfast Included

Exclusive studio in the heart of Amecameca de Juárez, just 15 meters from the bus terminal (Volcanes). It features a fully equipped bathroom, a spacious room, a TV and work area, an independent entrance, self check-in, and automated lighting. Enjoy its unique colonial-style façade and a delicious included breakfast. Perfect for relaxing or working comfortably. The only studio with these features in the city!

Top guest favorite
A charming mini cabin is displayed, featuring a brick exterior and a welcoming porch. Two red Adirondack chairs are positioned on the manicured lawn, surrounded by greenery. The clear blue sky and sunlight enhance the tranquil setting of this inviting retreat.
Cabin in Popo Park
4.97 out of 5 average rating, 99 reviews

cozy tiny house, adorable casa!

Relájate en pareja o con toda la familia en este alojamiento donde la tranquilidad se respira, adorable mini cabaña ubicada en zona boscosa, rodeada de cedros, un lugar ideal para descansar, hacer una carne asada, picnic o realizar home office. Pero no por eso dejar de disfrutar de tus series o películas favoritas en Netflix, MAX (HBO), Prime Video, Disney y/o partidos de futbol

Guest favorite
A spacious sleeping area features a large bed with light-colored bedding, complemented by a decorative coverlet displaying Parisian themes. The minimalist decor includes bedside shelves and a large headboard, enhancing the room's modern design and functionality.
Apartment in Mexico City
4.89 out of 5 average rating, 94 reviews

B Apartment, bathroom, minibar, garden and barbecue.

New apartment with a parking space, 10 blocks or 5 minutes from Terminal line 12 of the Tlahuac Metro, with a full bathroom, microwave oven, minibar, and sharing a large 500m garden with a wood and charcoal grill, and a gas grill in functional facilities for work and rest. Located on the first floor, it has a terrace where you can rest or simply sunbathe.

Superhost
Tiny home in Jardines del Pedregal de San Ángel
5 out of 5 average rating, 5 reviews

A little house in the garden. Next to CU

In the corner of a beautiful garden, this little house opens its doors for you to rest and feel comfortable, rest and listen to the birds at dawn. It has a bedroom, a bathroom, and a small kitchen for your convenience. Although it shares the entrance with the residence to which it belongs, the space is independent and memorable.

Superhost
The exterior of a wooden cabin features a distinct red roof and white accents. A garden of lavender blooms is visible in the foreground, complementing the wooden structure. The cabin's windows and door are framed to enhance the cabin's rustic charm.
Cabin in Amecameca
4.8 out of 5 average rating, 74 reviews

Cabana BC Amecameca

Relax on this unique and peaceful getaway in this beautiful cabin with beautiful landscapes of the volcanoes, open spaces and green areas. The cabin is well located near highway Mexico 115 with easy access to gasoline, convenience store (oxxo) and The Italian Coffee (3min by car, 10min walk).

Popular amenities for Santa Cruz vacation rentals

  1. Airbnb
  2. Mexico
  3. Santa Cruz