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Vacation rentals in Santa Cruz

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Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
An open courtyard displays vibrant orange walls with decorative plants in pots. A second level features a balcony adorned with hanging plants and strings of lights. The ground is paved, providing a spacious area that invites relaxation and outdoor gatherings.
Apartment in Centro
4.96 out of 5 average rating, 451 reviews

A Place Yours in Historical Center of Mexico City

Since 2018, Un Lugar Tuyo en Cdmx means Total Trust and Exclusivity with your family or friends; comfort, cleanliness, zero urban noise, independence, tranquility, security and rest. It consists of a small dining room and kitchen, bathroom and bedroom with 2 beds + 1 single, in a condominium property. Located on the first floor. With access to Metrobus, Metro Bellas Artes, 12 minutes from the Zócalo. Your long stay will be more comfortable with weekly and monthly discounts. Welcome the world!

Guest favorite
A sunlit living area features a mix of comfortable seating, with two wicker chairs and a wooden sofa. A glass coffee table sits at the center, surrounded by large windows offering views of the garden. Lush vegetation and flowering plants are visible outside.
Cabin in Mexico City
4.9 out of 5 average rating, 31 reviews

Cabin with garden and kitchen near chinampas

Escape to a 1,080 ft² cabin retreat nestled in Xochimilco’s UNESCO-protected chinampa zone. Bask in serenity with a 4,310 ft² private garden, inside free parking, and optional lake access. Inside, free parking, plush linens, a fan, complimentary tea, high-speed Wi-Fi, etc., await you—while modern security cameras ensure peace of mind. Stroll one minute to the Olympic track or lagoon, and 20 minutes to Xochimilco Centro. Unplug under a canopy of stars in this elegant, eco-friendly sanctuary.

Top guest favorite
A cozy bedroom features a single bed adorned with a striped blanket and decorative fringe. A small wooden desk and chair are positioned against the wall. Shelves display towels and toiletries. Light wood flooring complements the simple, colorful wall accents.
Guest suite in San Diego Churubusco
4.93 out of 5 average rating, 262 reviews

Coyoacán, Independent room with stove & bath

You will love my space because it is an independent Mexican style room with private bathroom and small space for cooking, table to work or eat. Fully remodeled, high quality mattress and wifi. Space safe, nice, bright and comfortable for one person. The room has its own entrance. Guest is given keys to the room and to the house entrance. Places of interest: Frida Kahlo Museum, Coyoacán, plus a direct walking through subway station direct to downtown. Perfect location for walking in City.

Guest favorite
The image captures a spacious terrace adorned with various potted plants, leading to a bright bedroom area. Large glass doors open to the patio, allowing natural light to fill the space. A serene landscape and a clear blue sky complement the vibrant greenery.
Loft in Santa María La Ribera
4.96 out of 5 average rating, 311 reviews

Sunny loft with a big terrace in a historic area

New and spacious two stories loft on an award winning renovated building from the 1940´s. Security 24/7 , personal digital code to access the apartment, wifi, fully equipped kitchen, Smart TV with Netflix/Mubi, and a shared laundry room in the building. The loft has one patio in the first floor and a huge terrace full of plants on the second floor next to the bedroom. It is usually very quite but there could be a little noise during the day if another apartment is doing renovations.

Guest favorite
An open-plan living area features a dining table with black chairs and a contrasting wooden surface. Natural light floods the space through large windows, illuminating a relaxed seating area and green plants. Decorative wall pieces add character to the minimalist design.
Loft in Santa Catarina
4.9 out of 5 average rating, 192 reviews

Casa Mavi's loft in Coyoacán

Welcome to Coyoacán! Great loft of 120 m2 located just 5 minutes walk from the center of Coyoacán. Live the experience of this quiet and bright open space, ideal for rest or work and decorated with objects full of stories. The loft is located on the third floor of Casa Mavi, a former factory that was remodeled to create a charming place that makes it unique. It has terraces for common use. With option for a third guest. Wifi 200 megabytes.

Top guest favorite
A spacious sleeping area features a large bed with dark striped bedding. Natural light floods the room through floor-to-ceiling windows, providing panoramic views of the cityscape and the Monumento a la Revolución. A small round tray is placed on the bed.
Loft in Juárez
5 out of 5 average rating, 69 reviews

Modern loft with incredible view in downtown area.

✨Enjoy a unique experience in this modern loft with spectacular views of the Monument to the Revolution. Located in the heart of Mexico City, in a new and safe building with luxury amenities, it is ideal for resting, exploring and enjoying. Relax in the indoor pool, hot tub, or spa, work out in the gym, or work in the coworking space. Steps from Reforma, near Bellas Artes, the Zócalo and surrounded by cafes and restaurants.

Top guest favorite
A staircase with wooden steps gently ascends against a textured light gray wall. Natural light filters through a large window, creating geometric shadows on the floor. A sleek kitchen countertop is partially visible, complementing the modern design.
Condo in Condesa
4.97 out of 5 average rating, 116 reviews

PH in Condesa_unique, unbeatable_in front of Lardo

This one of a kind and cozy pent-house is located inside one of the most emblematic developments built in La Condesa neighborhood. Its architecture is a contemporary version of Art Deco. A style that defines La Condesa. It is located in a beautiful, tree-lined area. The atmosphere is very family-oriented, with young and vibrant people. The surroundings invite us to step out, walk, relax and discover new experiences.

Top guest favorite
Apartment in Amecameca
4.96 out of 5 average rating, 25 reviews

Wulkan Studio+Breakfast Included

Exclusive studio in the heart of Amecameca de Juárez, just 15 meters from the bus terminal (Volcanes). It features a fully equipped bathroom, a spacious room, a TV and work area, an independent entrance, self check-in, and automated lighting. Enjoy its unique colonial-style façade and a delicious included breakfast. Perfect for relaxing or working comfortably. The only studio with these features in the city!

Top guest favorite
Loft in San Pedro El Chico
5 out of 5 average rating, 40 reviews

Private, clean and cozy apartment

A private, cozy and quiet space where you can have a pleasant stay in a friendly and respectful environment. The location is close to Benito Juárez International Airport and the Oriente and Norte bus terminals. There are different public transportation systems at the location, such as Taxi, Metrobus, Metro, Trolleybus, and private transportation, such as Uber and Didi.

Superhost
A spacious sleeping area features a large bed with light-colored bedding, complemented by a decorative coverlet displaying Parisian themes. The minimalist decor includes bedside shelves and a large headboard, enhancing the room's modern design and functionality.
Apartment in Mexico City
4.89 out of 5 average rating, 96 reviews

B Apartment, bathroom, minibar, garden and barbecue.

New apartment with a parking space, 10 blocks or 5 minutes from Terminal line 12 of the Tlahuac Metro, with a full bathroom, microwave oven, minibar, and sharing a large 500m garden with a wood and charcoal grill, and a gas grill in functional facilities for work and rest. Located on the first floor, it has a terrace where you can rest or simply sunbathe.

Guest favorite
An open living space features exposed brick walls and wooden beams. A cozy seating arrangement includes a sofa and a coffee table. A dining area is visible, surrounded by wooden chairs, with a staircase leading to an upper level illuminated by natural light from large windows.
Apartment in Roma Norte
4.91 out of 5 average rating, 100 reviews

Amazing place, amazing location

Departamento recién remodelado rescatando una casa de 1920 en el corazón de la Roma Norte. Ubicación excepcional, tranquilo, con mucha luz natural, dobles alturas en espacios interiores, ideal para disfrutar de la zona centro de la CDMX. A cuadras de los mejores restaurantes y bares de la Roma, muy fácil acceso. Ubicación incomparable.

Top guest favorite
A cozy living area features a gray sofa adorned with yellow cushions, complemented by a decorative lamp and artwork on the blue wall. A wooden coffee table holds a small plant and water bottles, enhancing the welcoming ambiance of the space.
Condo in Tabacalera
4.91 out of 5 average rating, 124 reviews

Beautiful and cozy mini apartment/near Reforma

A small apartment with an excellent location. The space is ideal for 2 people and has all the amenities needed for a pleasant stay. Just one block from the Monument to the Revolution, very close to Paseo de la Reforma and Av. Insurgentes. Located on the 1st floor (STAIRS MUST BE CLIMBED)

Popular amenities for Santa Cruz vacation rentals

  1. Airbnb
  2. Mexico
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