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Vacation rentals in Santa Cruz

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Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A sunlit living area features large windows framed by sheer curtains, offering views of lush greenery and the nearby water. Two wooden chairs are positioned around a low table on a neutral-colored rug, inviting relaxation in this spacious setting.
Apartment in Santa Cruz
4.93 out of 5 average rating, 107 reviews

Viento&Volcanes Guesthouse

Modern 2-Bedroom apartment with lake & volcano views, perfect for kite surfers and remote workers. Located just minutes from a top kite surf spot, our space offers modern comforts, stunning views, and everything you need for a memorable stay. Our spacious 2-bedroom apartment is fully equipped for your comfort. Both bedrooms feature premium queen and king beds, ensuring a restful night after a day of adventure. Each room has its own air conditioning to keep you cool during Ometepe’s warm days. The open-plan living area flows seamlessly into a private terrace, offering panoramic views of Lake Cocibolca and the majestic volcano. The kitchen is fully equipped with all the essentials for cooking, including a fridge, stove, oven, coffee maker and blender — perfect for preparing meals. For Remote Work: Stay connected with ease—our apartment comes with high-speed internet and a backup generator, ensuring you're always powered up, even during island power outages. Whether you're catching up on work or just want to relax in a peaceful environment, this place has everything you need. Prime Location: The apartment is ideally located just above a brand-new supermarket, making it super convenient for stocking up on essentials or grabbing a quick bite. Plus, it's only minutes away from a popular kite surfing spot, so you can easily hit the water whenever you’re ready. When you're not on the water, explore Ometepe's natural beauty, from hiking trails to tranquil beaches. Guests have exclusive access to the entire apartment, terrace, and surrounding garden. Whether you’re working, relaxing, or adventuring, you'll have plenty of space to enjoy your time on Ometepe. Come enjoy the best of Ometepe Island with all the modern comforts you need!

ValueFamilyView

Superhost
Home in Punta Santa Maria
4.92 out of 5 average rating, 224 reviews

Casa Isla Bonita (Cama king)

ISLA BONITA. Es una casa frente al lago privada rodeada de árboles y jardines con 2 habitaciones , 2 baños, amplio corredor con hamacas y comedor . Durante tu estancia en esta casa podrás disfrutar de las imponentes puestas de sol frente al volcán Consepción, nadar si se antoja , alquilar un kayak para remar a playa mangos o río istían Al costado izquierdo de la casa contamos un área pila , lavadora semiautomática , uso exclusivo de huéspedes, acá también encontrarás jabón y aroma para ropa.

ValueFamilySolo travel

Top guest favorite
The image captures a tranquil lakeside scene at dusk, with a large volcano rising in the background. Soft sunlight filters through the clouds, illuminating the landscape and reflecting on the water surface. The shoreline is dotted with greenery, creating a serene atmosphere.
Cottage in Santa Cruz
4.99 out of 5 average rating, 96 reviews

Bella Beach Casita on Ometepe w/kitchen, warm H20!

Private clean comfy tranquil secure w/lots of screened windows w/security bars, kitchen, fast WiFi w/router, warm H20 shower, ceiling fan/wall fan, organic gardens surrounded by a volcanic rock wall w/a step to longest stretch of sandy beach. Central location on paved Main Road Santa Cruz - near ATM, grocery/veg stalls/shops/restaurants. Pre-travel info, tours, hikes, taxis, activities. Thank you for supporting our local beach clean-ups & donations to our community efforts. 3 night minimum stay.

LocationFamilyLayout

Guest favorite
A comfortable porch area features a colorful hammock and a rocking chair, inviting relaxation. The view overlooks the lake, framed by trees, with a sunset casting warm tones across the sky and water. A sturdy picnic table sits nearby on the patio.
Home in Mérida
4.94 out of 5 average rating, 17 reviews

Casita Punta de Guavas

Enjoy beautiful sunsets & lake front living at Casita Punta de Guavas! Peaceful & serene, this 3 bedroom house is a short walk to all the restaurants & bars in Mérida. Views of Volcan Concepción, bird watching, swimming, kayaking. Our home has 3 bedrooms, bathroom with shower, kitchen with fridge & water filter. The well-ventilated house has great air flow. All windows & doors have screens. Solar system keeps WiFi on! (Ideal for digital nomads.) This is the place to stay on Isla de Ometepe!

LocationValueBathroom

Guest favorite
A charming cottage is shown from an angled view, featuring a wooden deck with a railing. The exterior walls are finished in blue, complemented by a stone base. Large windows allow natural light, while surrounding greenery adds a touch of nature to the setting.
Farm stay in Balgüe
4.92 out of 5 average rating, 24 reviews

Casa Mono Congo whole house rental

Casa Mono Congo is a modern, elegant cottage with verandas overlooking the farm, forests and lake. The house is within Finca Campestre with trails to explore the farm. It is about 15 minute from Balgue centre with paved road and level parking. It is very tranquil with little noise besides that of nature. We have abundant deer, guatusa, howler monkeys and red squirrels as well as many birds and butterflies within the farm year round, so wildlife spotting is something you can do from your veranda.

FamilyLocationKitchen

Top guest favorite
The image captures a serene sunset over calm waters, with two symmetrical volcanoes silhouetted against a vibrant orange sky. The sun descends slowly, reflecting golden hues across the water's surface, creating a tranquil atmosphere.
Guesthouse in San Fernando
4.96 out of 5 average rating, 75 reviews

Bungalow 3 guests-Casa Hernandez-Beach Access-wifi

Serene Beach Sunrises & Magical Tranquil Sunsets on Ometepe! Private Bungalow w/WiFi, clean bedroom & bathroom w/warm water showers! Patio w/hammock, table, seating - gardens - beach front property = longest stretch of sandy beach between 2 volcanoes on paved Main Road. Beautiful carved wood/glass door & windows - all screened w/metal bar protection plus ceiling fan. Natural wood ceiling & furniture with 1 dbl & 1 single bed. Ceramic tiled. Parking/Daily Housekeeping! Meals/laundry extra. Tours

ValueLocationAccess

Top guest favorite
Home in Santa Cruz
4.93 out of 5 average rating, 41 reviews

Casa en playa Santa Cruz

Estamos ubicados en playa Santa Cruz, la playa está cruzando la calle cerca hay supermercado y restaurantes. Es una casa muy ventilada y con gran iluminación natural está a orilla de la calle por lo debes tomar en cuenta que abra algo de ruido durante el día, pero es más tranquilo de noche, solo que en la mañana quizás puede oír un poco de ruido de los buses pasando, pero nuestra mayor ventaja es la playa, la mejor de la isla y la cercanía a otros sitios turísticos. También alquilamos scooters

ValueLocationComfort

Guest favorite
A spacious bedroom features a bamboo-framed bed draped with a mosquito net. The wooden floor is complemented by natural light filtering through the windows. Unique decor elements and textures create a calming environment, enhancing the overall comfort of the space.
Cabin in Balgüe
4.89 out of 5 average rating, 178 reviews

Selvista: Mango House - luxury volcano view

A tranquil nature retreat with all the comfort you crave. Soak in the "barefoot luxury" of your 3-story luxury treehouse, on the slopes of the Maderas volcano on Isla de Ometepe, Nicaragua. Relax in the modern comfort of a hot water shower, wifi, private balconies, and incredible panoramic volcano & lake views. Short walks to the center of the town or the Maderas trail! Ideal for couples, groups, business travelers, and families alike. We blend adventures & relaxation in nature. Join us

LocationValueSleep quality

Guest favorite
Cabin in Altagracia
4.95 out of 5 average rating, 19 reviews

Writer's cabin

Escape to a Serene Jungle Cabin on Ometepe Island Discover your own off-grid private cabin nestled among fruit trees and lush gardens, where the peaceful rhythms of island life set the tone for your stay. The cabin is fully private, with a cozy outdoor shower and the option to enjoy a bonfire under the stars. A Note on Remoteness: Our cabin is tucked away in nature. It’s perfect for light travelers and adventure seekers. Bring manageable luggage for the walk from the parking area.

LocationValueIndoor spaces

Top guest favorite
A minimalist bedroom features a spacious bed with crisp linens, set against a concrete wall. Natural light filters in through a window with open views, while a small wooden chair stands nearby. The room's neutral tones create a calm and serene environment.
Tiny home in Mérida
4.99 out of 5 average rating, 115 reviews

Casita #2 With Kitchen on Lakefront Property

Ometepe Casitas - Cabin with private Kitchen on peaceful and beautiful lakefront property in El Peru, Ometepe. Guest can swim at the calm beach and enjoy stunning views of both the Maderas and Concepcion Volcanoes, rent a kayak and paddle up to the Istian river, Rent a scooter and explore the rest of the island or just sit back and relax at the beach or terrace and see the sunset while watching monkeys and hundreds of birds and parrots flying back home to our neighboring trees.

LocationValueSleep quality

Top guest favorite
Home in Balgue
4.98 out of 5 average rating, 160 reviews

Casa Del Lago, Luxurious Beautiful Lakefront Home!

Welcome to your private lakefront paradise! This stunning 2BR/2BA luxury home offers unforgettable views of Concepción & Maderas Volcanoes, nestled in beautiful Maderas National Park. Wake up to lush surroundings, unwind in stylish comfort, and enjoy UV filtered water throughout the home, A/C, ceiling fans, hot water, Fibre optic internet and fast WiFi & smart TV. Perfect for families or friends—sleeps up to 6 guests (including children, strict limit).

ValueLocationDecor

Guest favorite
Cabin in Santa Cruz
5.0 out of 5 average rating, 10 reviews

Calma Ometepe 4 - AC Luxury Jungle Cabin

Calma | Boutique Sanctuary General Where minimalist design blends with the island’s raw beauty. A refined retreat designed for modern comfort within Ometepe’s natural landscape. The Space Featuring a premium King Size bed, AC, hot water, and high-speed fiber Wi-Fi. Enjoy the tropical breeze from your private terrace. The Location Perfectly situated walking distance from the sandy beach, the kitesurfing center, a supermarket, and local restaurants.

LocationHospitalityComfort

Popular amenities for Santa Cruz vacation rentals