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Vacation rentals in Santa Cruz de las Flores

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz de las Flores

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A modern kitchen features sleek white cabinets and a light-colored countertop. A gas stove is integrated into the cabinetry, with a stainless steel sink and faucet visible. A black refrigerator stands against one wall, and playful character figurines line the upper shelves.
Home in Lomas de San Agustín
4.92 out of 5 average rating, 143 reviews

La Casita!

Whether you're coming to visit, work, or accompany a family member, or because of our proximity, availability, or whatever reason you've chosen us, I assure you that we meet the platform's requirements and will make sure you have a super pleasant experience. Please let me know if there is anything you need to be more comfortable, and I will do my best to have it ready for you upon arrival. If you can't find transportation or how to get home, don't worry. Let me know and we can work something out.

Guest favorite
A cozy bedroom features a queen bed with soft bedding. Natural light filters through large windows adorned with elegant curtains. A bedside table with a decorative lamp adds warmth to the space, while a television is mounted on the wall for entertainment.
Loft in Americana
4.93 out of 5 average rating, 117 reviews

11 Beautiful QS luxe room @ La Americana AC, TV

Disfruta de una experiencia auténtica en este alojamiento 100% restaurado. Rescatamos toda su esencia y la mejoramos, ubicado en la colonia Americana, conocida por su oferta cultural, gastronómica y por estar cerca de la embajada. Habitación Numarán cuenta con: Cama Queen - colchón de última tecnología cafetera, copas de vino y destapa corchos TV de 40in con Netflix y HBO Refrigerador minibar Escritorio Espejo cuerpo completo Terraza compartida con vistas en el segundo piso del edificio

Guest favorite
A modern living area features a mounted television above a wooden media console. A potted plant adds a touch of greenery, while a small vase with flowers sits atop a side table. Natural light filters through sheer curtains, illuminating the neutral-toned walls.
Apartment in Obrera 1
4.93 out of 5 average rating, 102 reviews

Lego Depa / Rooftop Pool / Sofa Bed

Elegant and centrally located apartment that offers a unique and comfortable space for travelers looking for an unforgettable stay. The depa is located in the heart of Guadalajara, chapultepec/Americana area, offering easy access to the most popular attractions in the city including historical sights, the best food and cultural area (cafes, markets, bars, etc.). You'll enjoy a 360° view from our rooftop terrace. We have 2 terraces, a swimming pool and a fire pit.

Superhost
The exterior of the apartment showcases a modern two-story design with a prominent entrance. A soft glow emanates from the entrance light, illuminating the door adorned with the number 20. Large windows allow for visibility into the interior, with sheer curtains gently swaying.
Home in Tlajomulco de Zúñiga
4.91 out of 5 average rating, 124 reviews

Tlajomulco de Zúñiga. Vista Sur Residential.

Furnished horizontal apartment in a private condominium with amenities, children's play area, swimming pool, (for common use in the condominium), small natural lake within the subdivision, central park, jogging track, fast soccer field, WiFi terrace, shopping center, cultural center, kids zone, outdoor gym, 5 minutes from the outlet malls and 15 minutes from Punto Sur, 55 minutes from Chapala, 35 minutes from Jocotepec, 42 minutes from downtown Guadalajara.

Top guest favorite
A modern living area features a light gray sofa facing a stylish coffee table on a textured rug. A glass shelf filled with books and plants is situated beside a large window that provides natural light and views of the city.
Condo in El Campanario
4.97 out of 5 average rating, 145 reviews

Apartment south of GDL with amenities. In La Tijera

The apartment has air conditioning in the MAIN BEDROOM. The service is contracted separately. Additional cost of $99.00 pesos per day. Kick back and relax in this calm, stylish space. Brand new with two bedrooms. Spacious for 4 guests. With an option for a 5th [with extra cost]. With amenities [gym, playroom, workspace, cinema]. Great location. In the south of the city. 5 minutes from squares and supermarkets. We'll make your stay a pleasant one.

Top guest favorite
A cozy living area features two green chairs and a circular table, surrounded by lush plants. A spiral staircase leads to the upper level, while a vibrant wall art piece adds a touch of color against the rustic brick wall.
Guest suite in Camino Real
5 out of 5 average rating, 120 reviews

- Chapalita Gourmet Zone - EVERYTHING within walking distance

Mi pequeña y acogedora propiedad esta ubicada en una de las colonias mas tranquilas y seguras de Guadalajara donde podras descansar comodamente y ademas disfrutar de la vida exterior ya que alrededor de la zona en que se ubica, a unos cuantos pasos, encontraras muchísimos restaurantes, cafeterias, bares, antojitos, supermercados y todo lo que necesites para pasarla bien, asi como gozar tambien de la vida cultural de la glorieta Chapalita.

Guest favorite
A modern kitchen area features a round dining table surrounded by sleek, gray chairs. Decorative flowers are placed in a vase at the center of the table. Wood and white cabinetry is visible, along with appliances and a counter for meal preparation.
Home in Santa Cruz de las Flores
4.95 out of 5 average rating, 42 reviews

Entire Accommodation "Casa Zaragoza" | We invoice

Relax with the whole family in this modern home with a pool where tranquility is breathable. You do not need to bring anything, this accommodation has all the amenities, from cutlery and cooking utensils to spacious and cozy bedrooms, you just have to enjoy and relax either as a family or as a couple. Enjoy the air conditioning or the ceiling fan to cool off while listening to birdsong during the day.

Guest favorite
The room features a spacious bed covered in a yellow quilt, accompanied by a green pillow. A small desk with a chair is positioned beside the bed. A flat-screen TV mounted on the wall is visible, and light filters in through curtains covering a window.
Guest suite in Del Pilar Residencial
4.94 out of 5 average rating, 135 reviews

Cozy studio inside a private A/C complex

A studio within a private estate attached to a family home, with independent access. The estate has a walking trail, controlled access, and two entrances on major avenues. It's near squares such as Punto Sur and Galerías Santa Anita. There's an Aurrerá a few blocks away, as well as shops, a butcher, and other services. All food services such as Rappi and Uber Eats deliver to the home.

Top guest favorite
A dining area features a glass table surrounded by four black chairs, complemented by a dark wood sideboard. A lamp illuminates the space, while a cozy seating area with a light-colored sofa and patterned rug is visible in the background, enhancing the inviting ambiance.
Home in Santa Cruz de las Flores
4.99 out of 5 average rating, 81 reviews

Comfortable and beautiful house in the south of the city

Relax in this space, a comfortable and beautiful house south of the city, in a private subdivision with a security booth with controlled access, very close to downtown Tlajomulco, just 10 km from Punto Sur and Galerías Santa Anita, and a few meters from Lopez Mateos and Colima highway and many more places, special promotion for corporate trips or long stays, ask!!

Top guest favorite
A modern living space features a comfortable seating area with a sectional sofa and accent chairs. Natural light floods in through floor-to-ceiling sliding glass doors, leading to a balcony overlooking greenery. A dining table for four is positioned nearby, adding to the inviting atmosphere.
Apartment in Los Gavilanes
4.98 out of 5 average rating, 146 reviews

Exclusive Apartment in Punto Sur

Beautiful apartment, with gym, pool and multiple amenities, located in the best place to live south of the metropolitan area of Guadalajara, just a few steps from the Punto Sur shopping center, surrounded by restaurants, banks, cinema, prestigious shops, bars, etc. Very close to hospitals and with double access, both by López Mateos and by Camino Real to Colima.

Guest favorite
A cozy dining area is depicted with a round table surrounded by four white chairs. Above, a vibrant artwork featuring Charlie Chaplin adds character to the space. The kitchen area is visible in the background, equipped with modern appliances and sleek countertops.
Apartment in Zona Centro
4.87 out of 5 average rating, 326 reviews

Studio in downtown Guadalajara with a pool

🌿 Enjoy a studio with a separate entrance to the street, more privacy, very bright and a spacious kitchen. Ideal for couples or travelers looking for a comfortable space to rest and work. 📍 Location We are in the heart of the city. Walking distance to supermarkets, coffee shops, bus stops and fast routes.

Top guest favorite
A modern living area features a light gray sectional sofa with brown cushions and a glass coffee table. Decorative plants and vases add a touch of nature. Natural light filters through horizontal blinds, complementing the minimalist design and polished tile floor.
Home in Bosques de Santa Anita
4.96 out of 5 average rating, 147 reviews

1. Casa en Triventi (Zona Bosques de Santa Anita)

Nice house on the outskirts of Guadalajara, 3 full bathrooms and a half bathroom, with a king size bed, a double bed and 2 single beds, the house has a Roof Garden ideal for grilled meat, a swimming pool and a gym for common use because it is part of a subdivision.

Popular amenities for Santa Cruz de las Flores vacation rentals