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Vacation rentals in Santa Ana

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Top-rated vacation rentals in Santa Ana

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Guest favorite
The two-story guest house is framed by lush greenery, with a façade featuring arched windows and a welcoming entrance. A balcony runs along the upper level, adorned with vibrant flowers. The surrounding landscape includes tropical plants and trees, adding to the natural charm.
Home in San Juan de Oriente
4.83 out of 5 average rating, 98 reviews

Magical Laguna de Apoyo 2-Story Guest House

La Orquidea which opened in May of 2005 is the only private guest house snuggled in the crater on the shores of Laguna de Apoyo. It has been designed as your "home away from home" with complete kitchen, private bath, living and dining areas. Balconies from both levels of the home provide spectacular views of the cleanest laguna in Nicaragua. The tranquil enviroment is home to countless migrating and indigenous birds. We hope you will enjoy your time relaxing here, and soaking up the sun, taking a hammock on a two hour ride to nowhere or hiking the crater your house sits in. The two story guest house can accommodate up to 6 people. La Orquidea provides an alternative to hotels and crowded hospedajes. We look forward to seeing you soon.

Guest favorite
A serene pool area is framed by lush greenery and tropical plants, with several terracotta pots holding vibrant foliage. Shade sails provide protection from the sun, while the inviting blue water of the pool reflects the surrounding garden.
Home in Granada
4.79 out of 5 average rating, 28 reviews

Garden Cottage in Garden Paradise.

Keep it simple at this peaceful and centrally-located place. A unique spot that shares a lap pool and a pavilion in a garden setting. This casita features private bathroom with an outdoor private garden shower , AC, WiFi . The’ queen bed has 100%cotton sheets and a mosquito net. The pavilion has refrigerator, sink, microwave, coffee maker, blender , single electric burner and toaster oven plus tables and chairs for dining and relaxing.***There is no hot water but the water temp is not cold.

Top guest favorite
An aerial view captures the lush tropical landscape surrounding the lakefront property. The villa is nestled among vibrant greenery, with red-roofed structures visible amidst the trees. The tranquil blue waters of the Laguna de Apoyo create a stunning contrast with the verdant hillsides.
Home in Masaya
4.97 out of 5 average rating, 31 reviews

Lakefront Luxury at Casa Tuani

Casa Tuani is a luxurious lakefront Villa on the shores of the Laguna de Apoyo natural reserve. Here you will enjoy the epitome of indoor-outdoor living and soak in the spectacular panoramic laguna views. The home is right on the lakes edge so you can easily swim in the thermal waters or take out one of our kayaks. The vacation retreat is fully appointed with everything you need for a comfortable stay including a chef's kitchen, air-conditioned bedrooms, filtered water, barbeque and firepit.

Guest favorite
A vibrant yellow cabin is surrounded by lush greenery and tropical plants. An inviting stone pathway leads to the entrance, where two wooden chairs are set against the wall. Natural light filters through large windows, enhancing the cozy exterior of the cabin.
Guesthouse in Laguna de Apoyo
4.88 out of 5 average rating, 48 reviews

Casita Mango - Fully Equipped Cabin at the Laguna

Casita Mango is one of the two cabin we offer. It is located on the garden side with a nice partial view of the lake straight from your bed! We rent with A/C. Hot water and Smart Tv... everything you need to live long-term in full comfort while being in the jungle far far away from the city blues. Come relax in the shade, swim or float in a tube at the public beach, or take our Kayaks for an adventure on the lake! Breakfast available for 7.50 US$ per person Bring your pets for 7.50 US$

Guest favorite
The cabin is constructed from traditional materials, featuring a straw thatched roof and wooden walls. Large windows allow natural light to enter, framed by light fabric curtains. Surrounding tropical plants enhance the cabin's connection to nature.
Cabin in Granada
4.83 out of 5 average rating, 40 reviews

Traditional Cabin w/ private BR,kitchen,co-working

Welcome to CASA CARACOLA, our cosy accommodation, co-working and recreation village where comfort meets nature within the city. Experience the charm of our rustic cabins, where every detail is carefully crafted to ensure your stay is pleasant. Our comfortable, simple cabins and spacious rancho offer the perfect balance of relaxation, fun and work. Enjoy the serenity of our lush garden, get creative in our communal kitchen and stretch your muscles on our yoga platform or enjoy a meditation.

Guest favorite
A bamboo-roofed pavilion rests on a wooden deck overlooking the tranquil waters of Laguna de Apoyo. Vibrant flowering plants surround the area, blending with the natural landscape, and hills can be seen in the distance beneath a soft morning light.
Home in La Laguna Número 1
5 out of 5 average rating, 7 reviews

Casa del Alma – Private Oasis on Lake Apoyo

Casa del Alma is a 4-bedroom Laguna front sanctuary crafted by Driftwood Homes & Rentals. Designed for soul-deep rest and reconnection, it offers open-air living, an infinity pool, yoga deck, beach volleyball court, dock, and panoramic views of Laguna de Apoyo. Grounded in nature, elevated by design—this space invites you to slow down, stretch out, and settle into the rhythm of Laguna life. Ideal for families or friends. Please note: retreats, events, or group hosting are not permitted.

Top guest favorite
Aerial view of Isla Mirabel, surrounded by the serene waters of the lake, with lush greenery and fruit trees visible. The imposing Mombacho volcano stands majestically in the background, and a variety of boats can be seen dotting the water, enhancing the natural beauty of the area.
Island in El Encanto
5 out of 5 average rating, 48 reviews

Unique private island experience close to center!

Isla Mirabel is located less than 5 minutes from Marina Cocibolca and 10 min from the colonial Granada. The island is full of exuberant flowers and fruit trees and has and a beautiful view of the Mombacho volcano. The glass house blends in with the trees, providing privacy for your stay. Swim, kayak, or simply enjoy the beautiful surroundings. Transportation at check in and out is included. Extra transportation is $6 round trip. There are 3 restaurants right there at the port.

Guest favorite
The villa features an outdoor area with a lush pool surrounded by tropical plants. Large glass doors open to an airy living space, filled with modern furnishings. A second level showcases elegant artwork, enhancing the contemporary design of the home.
Home in Granada
5 out of 5 average rating, 8 reviews

Casa Tropical, urban oasis

Hosted by Tribal Hotel owners, Casa Tropical is located on a private gated street just two blocks from the hotel. This luxurious villa was meticulously designed and outfitted with custom, locally-made and imported mid-century modern furniture and accessories, Turkish kilims, and outstanding pieces of art. As with a Marrakech riad, it is built around a lush courtyard landscaped with palm trees and tropical plants and a beautiful pool with hand-made black and white tiles.

Superhost
A serene courtyard features a custom-tiled pool, surrounded by lush tropical greenery. Two lounge areas with striped cushions are positioned beside the pool, complemented by vibrant plants adding depth to the tranquil setting.
Home in Granada
4.93 out of 5 average rating, 150 reviews

The Casa Violeta - Relaxed Luxury in Granada

As seen in Architectural Digest, Condé Nast Traveler and Domino Magazine, Casa Violeta provides escape, peace, and tranquility in Granada's tropical, Spanish-Colonial town. Every booking includes access to highly curated travel tips and recs provided by the founder of El Camino Travel, Katalina Mayorga. Armed with her knowledge, you'll have direct access to one-of-a-kind experiences not available anywhere else and discover hidden gems to visit in this stunning country.

Guest favorite
The cabin interior features a spacious bed with a light blue mattress and a stripe-patterned blanket. A wooden desk with chairs is positioned beside the window, providing an open view of the surrounding greenery. Natural wood walls enhance the rustic charm of the space.
Cabin in Granada
5 out of 5 average rating, 7 reviews

Amazing View Cabin on Eco-Farm

This is one of the most unique places you could stay anywhere in Nicaragua. The cabin is on an eco-friendly working farm dedicated to biodiversity. We are located just 5 km outside of Granada on the highway to Masaya. From the farm you can see 5 different volcanoes and Lake Nicaragua. Your stay will go directly to planting trees. At present we have over 130 species of trees. You can hike to Laguna de Apoyo in one hour! The cabin has a private/indoor full bath.

Top guest favorite
An infinity pool reflects the clear blue sky, bordered by lush tropical greenery. A small island is visible across the calm lake waters, enhancing the serene setting. Comfortable loungers are positioned by the pool, inviting relaxation in a peaceful environment.
Island in Isletas de Granada
4.94 out of 5 average rating, 53 reviews

Private Island Near Granada:Peaceful-Unforgettable

The Whole Island is Yours to Enjoy! Just 10 minutes by boat from the UNESCO World Heritage city of Granada, this breathtaking private island villa on Lake Nicaragua offers the ultimate romantic escape. Completely secluded and surrounded by natural beauty, it’s a luxurious 8-guest sanctuary for relaxation, adventure and unforgettable moments. Expect a true WOW experience — one you’ll never forget! - Infinity Pool - Lakeside Yoga - Hanging Bed - Massages

Top guest favorite
A tranquil pool reflects clear blue water, framed by lush green tropical plants. Arched entryways lead to a seating area with minimalist furniture, enhancing the serene atmosphere created by the light-colored walls and natural stone flooring.
Home in Granada
4.98 out of 5 average rating, 89 reviews

Bao Bei : Wabi Sabi Colonial Villa

Welcome to Bao Bei, a 1930's colonial villa, meticulously restored with a minimalist, wabi sabi aesthetic. Located in the historic centre of Granada, Bao Bei is short walk away from all of Granada's attractions. Lose your sense of time exploring the colonial streets of Granada, or just lay back in your own private oasis. Bao Bei allows you to immerse yourself in Nicaraguan culture while experiencing unparalleled style and luxury.

Popular amenities for Santa Ana vacation rentals

  1. Airbnb
  2. Nicaragua
  3. Granada
  4. Santa Ana