
Vacation rentals in Panama Bay
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Panama Bay
Guests agree: these stays are highly rated for location, cleanliness, and more.

Luxury apt in Panama City 2 Rooms 3 Baths
El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Best location - Unique and charming loft
Relax and enjoy the elegance of a bygone era when you stay in this charming Loft. Carefully built with wooden floors, calicanto walls, high beamed ceilings and antique details for a luxurious yet charming feel. Take an early morning walk and enjoy the ruins, churches, and museums of Casco Viejo. Stroll through the historic streets while the city sleeps, then return for morning coffee in this classic and elegant Loft with a dreamy terrace. This apartment is located in the heart of Casco Viejo!

Bahia Breeze 3 rooms nature sanctuary with pool
Reconnect with nature in this spacious, serene private villa. Hiking, beach, sailing club, fishing or just relax in tranquility. Phenomenal views of Milky Way Galaxy at night. Watch Netflix or YouTube on big screen. Have a relaxing meal on the deck overlooking the Pacific. Tremendous effort to create a solar powered environmentally friendly private retreat immersed in nature. Depending on time of year, feel free to grab a papaya, lime, mango, avocado. Portion of proceeds to World Wildlife Fund

Panoramic Casco Viejo Lookout in The Sands
exquisite apartment blends cozy comfort with sophisticated luxury. Every detail radiates elegance, from the plush, high-end furnishings to the warm, inviting ambiance. The open-concept living area is perfect for relaxing or entertaining, with breathtaking views of the UNESCO World Heritage Casco Viejo framing the horizon. The compact kitchen has modern appliances, sleek countertops, and all essentials. With Casco Viejo vistas, this stylish retreat is perfect for exploring culture and history.

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES
Espectacular ático Duplex en Panamá Casco antiguo, de 265 M2 con balcones, terrazas privadas exterior, cuenta con una salón jardín interior, un comedor, 3 hab. (+ sofá cama en studio), recientemente reformado con concepto Loft, diseño exclusivo único y confortable, en la mejor zona del Casco viejo, perfecto para relajarse y desconectar, cocina , lavavajilla, sala con lavadora. piscina compartida, asc, portero 24-7, no se permiten niños que no sepan nadar, gran variedad de ocio en la zona.

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

The Crystal House: Luxury Modern Wood Cabin
Crea recuerdos inolvidables en este alojamiento único e ideal para familias. Quédate en una cabaña en medio del Parque Nacional Chagres a 50 minutos de la ciudad. Podrás estar en contacto con la naturaleza contando con todas las comodidades de un alojamiento de lujo. Con una de las mejores vistas a la ciudad puedes disfrutar de una buena barbacoa, una siesta en la hamaca o una reunión alrededor de la chimenea. Relájate y conéctate con el lindo verde de Panamá. Te esperamos!

Casa Rosie - Dream Home on Tabogá Island
Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Luxury Balcony Stays + Pool Casco Viejo
Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Gorgeous Flat in the best location in Casco Viejo
This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Cozy Apartment in the Heart of Casco Viejo
Thoughtfully designed, this elegant apartment with a full bedroom and another loft bedroom provides you with everything you need for a wonderful stay. Located in the heart of Casco Viejo, surrounded by beautiful colonial scenery, great restaurants, and existing night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.
Popular amenities for Panama Bay vacation rentals
Other great vacation rentals in Panama Bay

Pelicans's View, Seafront Apartment, private pool

Most Beautiful Loft in the Heart of Casco Viejo

Luxury Centric 2BR Apartment in Casco Viejo

Casco Antiguo Apartment with Balcony & Stone Wall

w* | Luxury 2BR in Old Town

Casa Condal - Your Luxury Retreat in Cerro Azul

Tropicool Casco Loft w/King Bed & Rooftop

A warm and cozy flat in Casco Viejo





