Vacation rentals in Muscatine

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Muscatine

Guests agree: these stays are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
Guest favorite
A historic four-bedroom home is captured with tall trees framing the exterior, set against a clear blue sky. The architectural features include a prominent turret and multiple windows, reflecting the home's charm. A snow-dusted yard leads to a view of the nearby Mississippi River.
Home in Muscatine
4.96 out of 5 average rating, 135 reviews

Historic West Hill Retreat

Beautiful historic 4 bedroom, 4 bath home within walking distance to shopping, bars/restaurants and all that downtown Muscatine has to offer. Enjoy sweeping views of the Mississippi River from several vantage points in and outside this home. The 3000 sf interior offers many places to gather and relax. Two of the bedrooms have on suite full baths. The other two bedrooms share a full bath. Additional amenities include, fully equipped kitchen, laundry, games, grill, outdoor entertainment area.

Top guest favorite
Two horseback riders are positioned on a grassy hill overlooking a tranquil pond. The clear water reflects the surrounding greenery, enhancing the serene rural setting. The landscape features rolling hills, contributing to a peaceful country experience.
Farm stay in Riverside
4.92 out of 5 average rating, 356 reviews

Farm stay close to Iowa City, IA

15 min.-Iowa City, 5 min- Riverside Casino, & 35 min-Eastern Iowa Airport, Cedar Rapids, IA. Comfy beds, living room sectional pulls out to queen hide a bed, 32 acres of rolling hills, horseback riding (sm. fee)*, winter fun, & fishing pond. First 2 guests pay base price, then 3rd thru 10th guests pay an extra 30.00 EACH. NO PARTIES on our farm. We live on property in a separate home. Dogs welcomed (must be kenneled when you leave property)NOTE: NO OVEN in kitchenette. *contact for details.

Superhost
A bright living space is highlighted by large windows that allow natural light to flood in. A comfortable seating area with green cushions contours the wall, providing a cozy nook. The kitchen features modern appliances and clean cabinetry, creating a functional cooking area.
Cabin in Cedar Rapids
4.83 out of 5 average rating, 160 reviews

Contemporary Tiny House & Low Tech Hot Tub

The tiny home experience. Kitchen, living room, closets, bathroom, & lofted bedroom are all masterfully tucked into 232 sq ft. Attractive backyard space complete with bistro lighting, & a minimalist seasonal hot tub ( No chemicals, no jets. Freshwater on demand hot water). Just minutes away from shopping areas, downtown, and great restaurants. It's just half a block from a local grocery store. Nine minutes from newbo. Your hosts will be available to help you acclimate to the fun experience.

Guest favorite
A spacious home is visible with a combination of brick and siding exterior, featuring multiple gables and a large covered porch. A manicured lawn extends toward a serene pond, enhancing the natural surroundings. Clear blue skies contribute to the relaxing outdoor atmosphere.
Home in Morning Sun
4.91 out of 5 average rating, 242 reviews

Buckman's Guesthouse BnB (5 Bedrooms+)

Enjoy the comfort and welcoming atmosphere of a home built to entertain family & friends. There are 5 guest bedrooms rooms: Room 1-King bed, sofa bed & recliner Room 2-Queen & sofa bed Room 3-Twin beds & convertible sofa Room 4-Queen & sofa bed Room 5-King & recliner Rooms 1,2 &5 have in suite bathrooms. Bathroom for room 4 is next door. Rooms 2 &3 share an inner door; ideal for parents with children. Breakfast is included. To book a room instead of the house, see separate listings.

Guest favorite
A cozy living area features a blue sofa and two wicker chairs, complemented by tropical-patterned pillows. A wooden coffee table sits atop a textured rug, with a television mounted on the wall. A potted plant adds a touch of greenery to the space.
Home in Davenport
4.91 out of 5 average rating, 154 reviews

Hidden Gem In The Quad Cities

Space is the upstairs of a duplex. Self check-in. Safe and friendly neighborhood. This special place is close to everything, making it easy to plan your visit. Note: Access requires steep stairs, so it may not suit guests with mobility concerns. Friendly owners live downstairs and are happy to assist. The place is close to St. Ambrose, Genesis West, Restaurants, 5 min from Palmer, Downtown and Mississippi Valley Fair grounds, 12 min from Augustana and 14 min from the Vibrant Arena.

Guest favorite
The entrance to the cottage features a decorative door framed by colorful trim. A wooden porch is accessed by a set of steps, and the house displays intricate architectural details, including a ceiling fan and house number on the door. Sunlight casts shadows across the entrance.
Cottage in Rock Island
4.94 out of 5 average rating, 309 reviews

Carla's Cottage

This little cottage is a Rock Island Historic house. Nestled among the large Victorians, it was built in 1879 and housed various workers, from a blacksmith, to a wallpaper hanger! Located just blocks from the Mississippi River you can walk along a paved bike path with gorgeous views. In the evening enjoy the vibrant nightlife, with music and a dinner playhouse! This tiny historic cottage is great for a quick night, but perfect for class reunions, weddings and the John Deer Classic!

Guest favorite
The exterior of a charming farmhouse is presented, featuring a white facade with a sloped roof. Lush green grass surrounds the front porch, which is shaded by large trees. A welcoming atmosphere is suggested by the open door and inviting entryway.
Home in Muscatine
4.97 out of 5 average rating, 112 reviews

Michelle's Place- The Farm House

Welcome to Michelle's Place- The Farm House. Where it's a farm feel, centrally located in town. It's a completely remodeled home with intentional planning and beautiful design for you to come rest at a home away from home. Close to parks, and walking trials while also only 4 minutes away from the historic downtown area! All aspects inside the home were uniquely picked by the host. With seasonal farm fresh varieties of berries, fruits, and vegetables to be enjoyed in your backyard!

Top guest favorite
A view of the open-concept space highlights a kitchen area with a green countertop and a stove. The living area features light brown and tan upholstery on the seating, complemented by green carpet. A ceiling fan is visible along with warm lighting throughout the space.
Loft in Muscatine
4.95 out of 5 average rating, 238 reviews

The Emerald Loft Apartment

Stay in a Historic District Downtown loft! River views. Nearby park, playground, bike trails, boat ramps & marina. Shopping, live music, & restaurants. Private entry with 1,000 sqr ft of space, open concept, full kitchen, TV, laundry, private bath, literally right in middle of everything. Check in at Creations by Oz "Jewelry, Wine, & Unique Finds". Enjoy a glass of wine upon check-in. Come hungry. Photo comments provide dining options within steps of the Emerald Room.

Top guest favorite
A balcony offers a view of the Mississippi River, featuring flower boxes with colorful blooms along the railing. Two chairs are positioned for relaxation, overlooking a landscaped area and nearby road, with additional greenery visible along the riverbank.
Apartment in Muscatine
5 out of 5 average rating, 32 reviews

Beautiful Condo Downtown with River Views

3rd Floor Condo in the old Hotel Muscatine 100 plus years old just totally refurbished condo with a Beautiful Balcony with view of bridge and Mississippi River 2 bedrooms 1 full bed bedroom and 1 queen bed bedroom with both views of river and bridge and a 1/2 bath bath and full bath with soaking tub and rain shower, stackable washer and dryer, full kitchen fully stocked, desk area, beautiful patio with chairs over looking lit up bridge and river Adults Only 2 Night Minimum

Top guest favorite
A neatly landscaped home with a dark blue exterior is set amidst green grass and vibrant flower beds. The entryway features a welcoming red door framed by a decorative wreath. The walkway leads to a set of steps, enhancing the home's approachable charm.
Home in Bettendorf
4.92 out of 5 average rating, 154 reviews

Amazing updated 2 bedroom home 2 bath.

Your family will be close to everything when you stay at this centrally-located place. In the heart of Bettendorf. Close to interstates, shopping, Bettendorf Sports Complex, Village of East Davenport. Off street parking. Garage access if needed. Plenty of space two beds and bath on main level. Lower rec room has additional bath and sleeping accommodations. Quiet street. Fenced in back yard. Private deck. This house has everything for a short stay or long stay.

Guest favorite
A living room features a leather sofa, two vintage armchairs, and a round ottoman, creating a cozy seating arrangement. Natural light enters through large windows framed with sheer curtains. Dark wooden flooring contrasts with the light-colored walls and decorative art pieces are displayed throughout.
Home in Burlington
4.89 out of 5 average rating, 193 reviews

The Fleetwood Bungalow with Dreamy Porch

Welcome to The Fleetwood Inn! A charming, cozy one-bedroom bungalow in the heart of Burlington, Iowa. Right between our bustling business district and our nostalgic downtown, this little house has vast character. My favorite feature is all the original built-ins and beams. You will love the Western American inspiration and vintage finds, modern touches throughout, and dreamy details in every corner. Just added a Saatva Organic mattress for extra comfort.

Guest favorite
Two Adirondack chairs face a glowing fire pit, surrounded by a grassy area. A swing set stands nearby, and the tranquil water reflects the colors of the sunset. Smoke gently rises into the evening sky, creating a relaxed atmosphere.
Cabin in Moline
4.93 out of 5 average rating, 209 reviews

Autumn Escape w/ Firepit Nights, Kayaks & Bikes

🍂 Cozy up by the firepit and watch stunning sunsets over the Rock River. Enjoy crisp fall air from your private deck, complete with kayaks, bikes, and peaceful water views. This eclectic cabin bungalow offers vibrant décor, cozy living spaces, and a large wrap-around deck perfect for relaxing. Just steps from the water and close to shops and restaurants, it’s a serene riverside retreat for couples, families, and friends.

Popular amenities for Muscatine vacation rentals

When is the best time to visit Muscatine?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceﺩ.ﺇ507ﺩ.ﺇ507ﺩ.ﺇ507ﺩ.ﺇ507ﺩ.ﺇ514ﺩ.ﺇ507ﺩ.ﺇ536ﺩ.ﺇ595ﺩ.ﺇ657ﺩ.ﺇ507ﺩ.ﺇ507ﺩ.ﺇ507
Avg. temp-5°C-2°C4°C11°C17°C22°C24°C23°C19°C12°C5°C-2°C

Quick stats about vacation rentals in Muscatine

  • Total vacation rentals

    Explore 20 vacation rentals in Muscatine

  • Nightly prices starting at

    Muscatine vacation rentals start at ﺩ.ﺇ257 per night before taxes and fees

  • Verified guest reviews

    Over 790 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Wi-Fi availability

    20 of Muscatine vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Muscatine rentals

  • 4.8 Average rating

    Muscatine stays are highly rated by guests—averaging 4.8 out of 5!

  1. Airbnb
  2. United States
  3. Iowa
  4. Muscatine County
  5. Muscatine