Vacation rentals in Muscatine

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Top-rated vacation rentals in Muscatine

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A historic four-bedroom home is captured with tall trees framing the exterior, set against a clear blue sky. The architectural features include a prominent turret and multiple windows, reflecting the home's charm. A snow-dusted yard leads to a view of the nearby Mississippi River.
Home in Muscatine
4.96 out of 5 average rating, 142 reviews

Historic West Hill Retreat

Beautiful historic 4 bedroom, 4 bath home within walking distance to shopping, bars/restaurants and all that downtown Muscatine has to offer. Enjoy sweeping views of the Mississippi River from several vantage points in and outside this home. The 3000 sf interior offers many places to gather and relax. Two of the bedrooms have on suite full baths. The other two bedrooms share a full bath. Additional amenities include, fully equipped kitchen, laundry, games, grill, outdoor entertainment area.

Guest favorite
A charming duplex features a yellow exterior with white trim and a gabled roof. A staircase leads to a covered front porch, while large windows provide natural light. The surrounding yard is well-maintained, and a fence outlines the property, enhancing privacy.
Home in Davenport
4.91 out of 5 average rating, 157 reviews

Hidden Gem In The Quad Cities

Space is the upstairs of a duplex. Self check-in. Safe and friendly neighborhood. This special place is close to everything, making it easy to plan your visit. Note: Access requires steep stairs, so it may not suit guests with mobility concerns. Friendly owners live downstairs and are happy to assist. The place is close to St. Ambrose, Genesis West, Restaurants, 5 min from Palmer, Downtown and Mississippi Valley Fair grounds, 12 min from Augustana and 14 min from the Vibrant Arena.

Guest favorite
The entrance to the cottage features a decorative door framed by colorful trim. A wooden porch is accessed by a set of steps, and the house displays intricate architectural details, including a ceiling fan and house number on the door. Sunlight casts shadows across the entrance.
Cottage in Rock Island
4.94 out of 5 average rating, 312 reviews

Carla's Cottage

This little cottage is a Rock Island Historic house. Nestled among the large Victorians, it was built in 1879 and housed various workers, from a blacksmith, to a wallpaper hanger! Located just blocks from the Mississippi River you can walk along a paved bike path with gorgeous views. In the evening enjoy the vibrant nightlife, with music and a dinner playhouse! This tiny historic cottage is great for a quick night, but perfect for class reunions, weddings and the John Deer Classic!

Top guest favorite
The living area features a spiral staircase leading to the upper level, a gas fireplace set within a stone wall, and large French doors allowing bright natural light. A cozy seating arrangement includes a patterned chair next to a side table, with a decorative area rug adorning the floor.
Cottage in Le Claire
4.97 out of 5 average rating, 527 reviews

Mississippi Overlook Cottage, LLC. Dogs welcome.

Settle into a fully renovated 1910 cottage perched on a steep hill above Buffalo Bill Cody’s original homestead. Enjoy a charming park right behind you and stunning river views in front. The cottage comfortably accommodates up to six guests. Before booking, please note: - The cottage is located on a steep hill. - You will hear trains, as LeClaire is a river and train town. 🚂🌊 - This is a wooded property, so expect sticks, leaves, and bugs. 🌿🐞 - There are many steps.

Guest favorite
A view of the open-concept space highlights a kitchen area with a green countertop and a stove. The living area features light brown and tan upholstery on the seating, complemented by green carpet. A ceiling fan is visible along with warm lighting throughout the space.
Loft in Muscatine
4.95 out of 5 average rating, 240 reviews

The Emerald Loft Apartment

Stay in a Historic District Downtown loft! River views. Nearby park, playground, bike trails, boat ramps & marina. Shopping, live music, & restaurants. Private entry with 1,000 sqr ft of space, open concept, full kitchen, TV, laundry, private bath, literally right in middle of everything. Check in at Creations by Oz "Jewelry, Wine, & Unique Finds". Enjoy a glass of wine upon check-in. Come hungry. Photo comments provide dining options within steps of the Emerald Room.

Top guest favorite
A balcony offers a view of the Mississippi River, featuring flower boxes with colorful blooms along the railing. Two chairs are positioned for relaxation, overlooking a landscaped area and nearby road, with additional greenery visible along the riverbank.
Apartment in Muscatine
5 out of 5 average rating, 35 reviews

Beautiful Condo Downtown with River Views

3rd Floor Condo in the old Hotel Muscatine 100 plus years old just totally refurbished condo with a Beautiful Balcony with view of bridge and Mississippi River 2 bedrooms 1 full bed bedroom and 1 queen bed bedroom with both views of river and bridge and a 1/2 bath bath and full bath with soaking tub and rain shower, stackable washer and dryer, full kitchen fully stocked, desk area, beautiful patio with chairs over looking lit up bridge and river Adults Only 2 Night Minimum

Top guest favorite
A neatly landscaped home with a dark blue exterior is set amidst green grass and vibrant flower beds. The entryway features a welcoming red door framed by a decorative wreath. The walkway leads to a set of steps, enhancing the home's approachable charm.
Home in Bettendorf
4.92 out of 5 average rating, 169 reviews

Amazing updated 2 bedroom home 2 bath.

Your family will be close to everything when you stay at this centrally-located place. In the heart of Bettendorf. Close to interstates, shopping, Bettendorf Sports Complex, Village of East Davenport. Off street parking. Garage access if needed. Plenty of space two beds and bath on main level. Lower rec room has additional bath and sleeping accommodations. Quiet street. Fenced in back yard. Private deck. This house has everything for a short stay or long stay.

Guest favorite
A wooden deck features two chairs and a small table, overlooking the serene Mississippi River. Large glass doors open from the cottage, enhancing the indoor-outdoor flow. The river and sky are visible in the background, providing a scenic view.
Cottage in Moline
4.92 out of 5 average rating, 178 reviews

Stylish Riverfront Cottage in the Heart of the QC

This warm and unique cottage has a vintage meets modern theme. You will be just 50 ft off the Mississippi river! Enjoy panoramic river views in a vibrant area with great restaurants and coffee shops a short 2 min walk on the scenic QC River Way. You get the privacy of the ENTIRE home and so be noisy if you want-a 100watt stereo system is there for you to enjoy music & movies. Deluxe amenities ensure your comfort; outside has a 3-seasons room, deck, fire pit.

Superhost
Cottage in Rock Island
4.86 out of 5 average rating, 222 reviews

Rock River Escape

Enjoy your coffee, a nice bbq dinner, glass of wine, a good book, or just enjoy the sweeping views out of this cute bungalow. With 180 ft of unobstructed river views and river access, bring your fishing poles and get ready to relax and enjoy watching the water slowly drift by at this centrally located bungalow in a quiet residential neighborhood. Firepit with firewood provided. No parties allowed so please do not inquire about them.

Guest favorite
Two Adirondack chairs face a glowing fire pit, surrounded by a grassy area. A swing set stands nearby, and the tranquil water reflects the colors of the sunset. Smoke gently rises into the evening sky, creating a relaxed atmosphere.
Cabin in Moline
4.94 out of 5 average rating, 221 reviews

Riverfront w/ Firepit + Kayaks | Huge Deck Views

Wake up to sweeping Rock River views, sip coffee on the wrap-around deck, paddle out in the kayaks, and end your evening by the firepit as the sky glows at sunset. This eclectic riverfront bungalow blends vibrant décor with cozy comfort and seamless indoor-outdoor living. Perfect for girls’ weekends, fishing trips, romantic escapes, or peaceful fall getaways — just steps from the water and minutes to shops and dining

Guest favorite
Bungalow in Bettendorf
4.87 out of 5 average rating, 211 reviews

River Retreat

Welcome to our River Retreat. This house is situated at the end of a quiet dead end road right on the Mighty Mississippi River. Fully furnished with Wifi, washer/dryer and everything you need for a quiet and relaxing get away. Enjoy the river views from the deck and 3 season porch or relax in living room with a movie. Extra furnishings include a fire pit and charcoal grill. Book your stay today!!!

Top guest favorite
An open living area is highlighted by a large flat-screen television set on a low coffee table. A cozy electric fireplace is integrated into the media unit. The kitchen features a spacious island with four bar stools, complemented by modern appliances and inviting natural light.
Apartment in Moline
4.98 out of 5 average rating, 124 reviews

Cozy 2 bedroom Apt#4, large island, open concept

Open concept quiet apartment with all the amenities. Large island, fireplace, fully furnished kitchen, coffee station, appliances including washer and dryer, private entrance, and designated parking space. Near John Deer road, Black Hawk college, 2 miles from I74, 10 minutes to TPC Deere Run Golf Course, close to grocery store, and restaurants

Popular amenities for Muscatine vacation rentals

When is the best time to visit Muscatine?

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Avg. priceﺩ.ﺇ507ﺩ.ﺇ507ﺩ.ﺇ507ﺩ.ﺇ507ﺩ.ﺇ514ﺩ.ﺇ507ﺩ.ﺇ536ﺩ.ﺇ595ﺩ.ﺇ657ﺩ.ﺇ595ﺩ.ﺇ657ﺩ.ﺇ657
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Quick stats about vacation rentals in Muscatine

  • Total vacation rentals

    Explore 20 vacation rentals in Muscatine

  • Nightly prices starting at

    Muscatine vacation rentals start at ﺩ.ﺇ294 per night before taxes and fees

  • Verified guest reviews

    Over 780 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Wi-Fi availability

    20 of Muscatine vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Muscatine rentals

  • 4.8 Average rating

    Muscatine stays are highly rated by guests—averaging 4.8 out of 5!

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