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House vacation rentals in Mytilini

Find and book unique houses on Airbnb

Quick stats about house rentals in Mytilini

  • Total vacation rentals

    Explore 100 vacation rentals in Mytilini

  • Nightly prices starting at

    Mytilini vacation rentals start at ﺩ.ﺇ 73 per night before taxes and fees

  • Verified guest reviews

    Over 2,200 verified reviews to help you choose

  • Family-friendly vacation rentals

    40 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 30 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    100 of Mytilini vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mytilini rentals

  • 4.8 Average rating

    Mytilini stays are highly rated by guests—averaging 4.8 out of 5!

Top-rated house rentals in Mytilini

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
A newly built villa is shown beside a sandy beach, featuring blue shutters and a shaded outdoor seating area. A tree provides natural shade, with the crystal blue waters visible in the background, and distant mountains lining the horizon under a clear sky.
Home in Plomari
4.89 out of 5 average rating, 102 reviews

Floras Charming Waterfront Villa

Flora's charming waterfront villa is located in the centre of the traditional picturesque village of Melinda, situated 6 km west of the village of Plomari. Our villa is situated literally on the beach, which is known for its crystal blue waters. The newly built modern house is fully equipped with all conveniences, such as a modern kitchen, air condition units in all rooms, tv, wi-fi etc. The famous traditional greek taverna of Maria is right next door, where you can enjoy local delicacies all day. In Our quiet villa you will experience greek at its summer, watching the sunset.

Top guest favorite
A dining table set on an outdoor terrace is arranged for a meal. Plates are placed beside crystal glasses, with a colorful spread of grapes, watermelon, and other fruits displayed on a platter. A glass pitcher and bottles, including a wine bottle, complete the inviting setting.
Home in Mytilini
4.98 out of 5 average rating, 91 reviews

Aegean View Resort # The House

Tranquillity, relax and comfort best describe this house set in absolute nature in a peaceful suburb, only a few minutes away from the heart of the Mitilini. The property featuring stunning architectural details that provides guests with a high level of comfort and style but it can also be your base for exploring the rest of the beautiful and big island.It is perfect for families, couples or a group of friends looking for spacious areas, large terraces, comfort and privacy.

Top guest favorite
The tranquil night view captures three modern villas framed by lush greenery. A private pool is illuminated in soft blue, reflecting the clear sky. Warm light glows from the villas, highlighting their welcoming architecture against the serene backdrop.
Home in Mytilini
5.0 out of 5 average rating, 18 reviews

Pierres Blanches Residences 2

Discover the ultimate accommodation experience 1.5 km from the city center of Mytilene. With elegant design and modern amenities, our three autonomous detached houses, 120 sq.m. each, invite you to enjoy the tranquility and beauty of the island. Each villa has three comfortable bedrooms, two bathrooms, a spacious living room, an attic, a fully equipped kitchen and a private pool to cool off and enjoy the sun in the comfort of your own pool.

Top guest favorite
Home in Mytilini
4.95 out of 5 average rating, 22 reviews

Modern House in Mytilene Center

The house is located in the city center, a short distance from supermarkets, pharmacy, bakery, central market, urban/interurban transport and taxi rank. Its location is ideal to get to know the city, to browse the traditional alleys of the central market with its shops, cafes and restaurants, just 500 m away. To visit its imposing castle and the beautiful organized beach "Tsamakia" at a distance of 1.3 km.

Guest favorite
The exterior showcases a two-story traditional building with maroon shutters framing the windows, which are adorned with white lace curtains. A small outdoor seating area features a patterned tablecloth, complemented by light-colored chairs, inviting relaxation in a serene setting.
Home in Taxiarches
4.81 out of 5 average rating, 113 reviews

PanDesSia

"PanDesSia" is a traditional house in Mytilene, with Lesbian architecture. It is located in "Kayani", close by the famous "Antonis" Ouzeri. Offers a veranda with a fantastic view of the Aegean Sea, the town and the harbor of Mytilene and the Turkish coasts. It is only 6km from the town of Mytilene and 4km from the airport. It has two bedrooms overlooking the sea and can accommodate at least 4 people.

Guest favorite
A niche with a wooden ledge showcases two woven baskets, providing storage for items. The soft lighting enhances the neutral tones of the walls, leading to a spacious area beyond. Visible are elements of a minimalist design, contributing to a functional living space.
Home in Plomari
4.92 out of 5 average rating, 39 reviews

G&D studio

Our D&G studio is ideal for 2 people with the possibility of accommodating 1 more. It is located on the second level of a complex in the beautiful area of Agios Isidoros in the town of Plomari, Lesvos. On the balcony, there is a dining area where you can enjoy your coffee or a glass of wine overlooking the Aegean Sea and the wonderful sunset, experiencing the ultimate relaxation that the area offers.

Guest favorite
A double bed is positioned in a softly lit room, adorned with floral patterned bedding. A piece of wall art depicting a sunset is displayed above the bed, while decorative flowers frame the image. A warm ambiance is created by the light entering through a nearby window.
Home in Mytilini
4.83 out of 5 average rating, 41 reviews

Gina 's Cozy nest in Mytilene

Welcome to our apartment in the heart of Mytilene! Just steps away from restaurants and bars, we offer a comfortable double bed, personal care essentials, a fully equipped kitchen, a washing machine, and an iron. Enjoy free high-speed WiFi, a smart TV with Netflix, and air conditioning. We invite you to experience a unique stay filled with comfort, authentic hospitality, and unforgettable moments.

Top guest favorite
Home in Mytilini
5.0 out of 5 average rating, 20 reviews

Mytilene Luxury Villa | Garden level

Enjoy the private garden level apartment of our luxury villa with 3 bedrooms and panoramic views over Mytilene and the Aegean Sea. You’ll have a private entrance, exclusive use of the garden and outdoor areas, ensuring complete privacy. Just 5–7 minutes by car from Mytilene center, the port, and restaurants. Perfect for families and friends looking for comfort, style, and peace.

Top guest favorite
A cozy seating area is positioned near large windows overlooking the sea. The stone wall adds a rustic touch, while two tall chairs with green cushions invite relaxation. Natural light floods the space, highlighting the nearby decorative items and the calm waters outside.
Home in Nyfida
4.93 out of 5 average rating, 29 reviews

Pelagia's House

Pelagia's house is a seaside house that has been recently renovated while keeping its traditional character along with the memories of many carefree summers. The house has 2 bedrooms with one double and two single beds, a fully equipped kitchen, a very comfortable bathroom, air conditioning and wifi in all areas This seaside house is ideal for a quiet and relaxing vacation.

Guest favorite
Home in Mytilini
5.0 out of 5 average rating, 15 reviews

D. Bernardaki Garden House

Welcome to Bernardaki Garden House! Nestled in a traditional neighbourhood, our professionally designed apartment offers the perfect blend of modern comfort and timeless charm in the heart of Mytilene. Why does our proposal stand out among the options in the whole Mytilene? There's a reason, and we're eager to share it with you!

Top guest favorite
Home in Plomari
5.0 out of 5 average rating, 29 reviews

Villa olya plomari

A unique private villa in Plomari, with a breathtaking sea view, a quiet place, next to a pine forest with a luxurious private infinity pool and in the courtyard two sun beds and a dining area under an olive tree in front of the beautiful view of the sea and the village of Plomari. A perfect vacation.

Guest favorite
An open-plan living area features a light stone wall alongside a modern kitchen. A spacious beige sofa is complemented by two cozy poufs and a round area rug. Natural light filters through large windows, illuminating the space, while a dining table with wooden chairs is positioned nearby.
Home in Mytilini
4.88 out of 5 average rating, 16 reviews

Aeolian Apartment

Discover the perfect blend of comfort, design, and convenience in our beautifully designed 2-bedroom home, just a 5-minute walk from the vibrant city center of Mytilene. Nestled in a peaceful neighborhood, our space is ideal for those who want to explore the city while enjoying a tranquil retreat.

Popular amenities for Mytilini house rentals

When is the best time to visit Mytilini?

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Avg. priceﺩ.ﺇ 257ﺩ.ﺇ 250ﺩ.ﺇ 253ﺩ.ﺇ 301ﺩ.ﺇ 342ﺩ.ﺇ 353ﺩ.ﺇ 327ﺩ.ﺇ 382ﺩ.ﺇ 305ﺩ.ﺇ 275ﺩ.ﺇ 272ﺩ.ﺇ 264
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