
House vacation rentals in Mytilini
Find and book unique houses on Airbnb
Quick stats about house rentals in Mytilini

Total vacation rentals
Explore 100 vacation rentals in Mytilini

Nightly prices starting at
Mytilini vacation rentals start at ﺩ.ﺇ 73 per night before taxes and fees

Verified guest reviews
Over 2,200 verified reviews to help you choose

Family-friendly vacation rentals
40 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wi-Fi availability
100 of Mytilini vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mytilini rentals

4.8 Average rating
Mytilini stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Mytilini
Guests agree: these houses are highly rated for location, cleanliness, and more.

Floras Charming Waterfront Villa
Flora's charming waterfront villa is located in the centre of the traditional picturesque village of Melinda, situated 6 km west of the village of Plomari. Our villa is situated literally on the beach, which is known for its crystal blue waters. The newly built modern house is fully equipped with all conveniences, such as a modern kitchen, air condition units in all rooms, tv, wi-fi etc. The famous traditional greek taverna of Maria is right next door, where you can enjoy local delicacies all day. In Our quiet villa you will experience greek at its summer, watching the sunset.

Agiasos Classic Stone House
Enjoy your vacation in this calm and stylish place. It was renovated in 2024 with a lot of love and detail to offer moments of carefree living. Stone, two-storey, traditional house. 1st floor bedroom with king-size bed (1.80m) and internal staircase. 2nd floor * living room with sofa that becomes a double bed, dining room, kitchen, bathroom, balcony. The house from the second floor has a wonderful view of the chestnut grove. 5 min walk to the village center There is no parking space

Aegean View Resort # The House
Tranquillity, relax and comfort best describe this house set in absolute nature in a peaceful suburb, only a few minutes away from the heart of the Mitilini. The property featuring stunning architectural details that provides guests with a high level of comfort and style but it can also be your base for exploring the rest of the beautiful and big island.It is perfect for families, couples or a group of friends looking for spacious areas, large terraces, comfort and privacy.

Pierres Blanches Residences 2
Discover the ultimate accommodation experience 1.5 km from the city center of Mytilene. With elegant design and modern amenities, our three autonomous detached houses, 120 sq.m. each, invite you to enjoy the tranquility and beauty of the island. Each villa has three comfortable bedrooms, two bathrooms, a spacious living room, an attic, a fully equipped kitchen and a private pool to cool off and enjoy the sun in the comfort of your own pool.

PanDesSia
"PanDesSia" is a traditional house in Mytilene, with Lesbian architecture. It is located in "Kayani", close by the famous "Antonis" Ouzeri. Offers a veranda with a fantastic view of the Aegean Sea, the town and the harbor of Mytilene and the Turkish coasts. It is only 6km from the town of Mytilene and 4km from the airport. It has two bedrooms overlooking the sea and can accommodate at least 4 people.

G&D studio
Our D&G studio is ideal for 2 people with the possibility of accommodating 1 more. It is located on the second level of a complex in the beautiful area of Agios Isidoros in the town of Plomari, Lesvos. On the balcony, there is a dining area where you can enjoy your coffee or a glass of wine overlooking the Aegean Sea and the wonderful sunset, experiencing the ultimate relaxation that the area offers.

Mytilene Luxury Villa | Garden level
Enjoy the private garden level apartment of our luxury villa with 3 bedrooms and panoramic views over Mytilene and the Aegean Sea. You’ll have a private entrance, exclusive use of the garden and outdoor areas, ensuring complete privacy. Just 5–7 minutes by car from Mytilene center, the port, and restaurants. Perfect for families and friends looking for comfort, style, and peace.

Pelagia's House
Pelagia's house is a seaside house that has been recently renovated while keeping its traditional character along with the memories of many carefree summers. The house has 2 bedrooms with one double and two single beds, a fully equipped kitchen, a very comfortable bathroom, air conditioning and wifi in all areas This seaside house is ideal for a quiet and relaxing vacation.

D. Bernardaki Garden House
Welcome to Bernardaki Garden House! Nestled in a traditional neighbourhood, our professionally designed apartment offers the perfect blend of modern comfort and timeless charm in the heart of Mytilene. Why does our proposal stand out among the options in the whole Mytilene? There's a reason, and we're eager to share it with you!

Traditional House
Stay with the whole family in this lovely accommodation with lots of space for moments of joy. The property is located near beautiful beaches As in the neighboring village of Panagiouda, you will find many markets, cafes, a gas station and leisure shops - taverns The city of Mytilene is 10-12 minutes away.

Villa olya plomari
A unique private villa in Plomari, with a breathtaking sea view, a quiet place, next to a pine forest with a luxurious private infinity pool and in the courtyard two sun beds and a dining area under an olive tree in front of the beautiful view of the sea and the village of Plomari. A perfect vacation.

Aeolian Apartment
Discover the perfect blend of comfort, design, and convenience in our beautifully designed 2-bedroom home, just a 5-minute walk from the vibrant city center of Mytilene. Nestled in a peaceful neighborhood, our space is ideal for those who want to explore the city while enjoying a tranquil retreat.
Popular amenities for Mytilini house rentals
House rentals with a pool

Ouzo Traditional House with privatepool & parking

Twostorey house with amazing view (Aqua)

Tranquil Haven with private pool by Sea Sun

Galini Ducks

Eleia Villa with Private Pool and Sea View

Eros' sea view Mytilini (A)

Ouzo Panoramic 2B (3BR Superior Private Pool)

Luxurious Villa with Private Pool #2
Weekly house rentals

Casa de Pera In Town

Hidden gem checkpoint-Rodanthemo

Modern house by the sea

Efi's Home

Mcm Luxury & Traditional house

Modern House in Mytilene Center

Ambelos, Lesvos Beach House

Gina 's Cozy nest in Mytilene
Private house rentals

Villa with Sea View Bedroom in Yera Bay, Lesvos

Traditional Stone House in Seafront Olive Grove

Iasmos

Detached house in the city center

Yataki Cozy House in Plomari

Timeless charm with commanding sea views

MOLAV Apartment

Leda Hamam House
When is the best time to visit Mytilini?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ 257 | ﺩ.ﺇ 250 | ﺩ.ﺇ 253 | ﺩ.ﺇ 301 | ﺩ.ﺇ 342 | ﺩ.ﺇ 353 | ﺩ.ﺇ 327 | ﺩ.ﺇ 382 | ﺩ.ﺇ 305 | ﺩ.ﺇ 275 | ﺩ.ﺇ 272 | ﺩ.ﺇ 264 |
| Avg. temp | 8°C | 9°C | 11°C | 15°C | 20°C | 25°C | 28°C | 28°C | 23°C | 19°C | 14°C | 10°C |





