Vacation rentals in Middlesex County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Middlesex County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

A modern studio apartment is presented, showcasing a spacious sitting area with a large flat-screen television mounted above a contemporary electric fireplace. The open kitchen features updated appliances and a dining table for four, complemented by warm lighting and wood accents.

Guest suite in London

4.98 out of 5 average rating, 241 reviews

Modern and private guest suite

We've recently renovated our basement to create a stylish, modern, cozy and quiet guest suite. There is a side entrance that opens directly onto stairs taking you down to the unit. It has a locking metal exterior door for sound-proofing and security. The unit is a bright studio apartment with three large windows, a full kitchen, sitting area with tv and fireplace, dining table, queen-sized bed, walk-in closet and your own private bathroom with a five-foot shower. With extensive sound-proofing!

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Guest favorite

A spacious living area features a comfortable sectional sofa adorned with decorative pillows. A modern coffee table sits at the center, and a large TV is mounted on the wall. Artwork is displayed to the side, creating a welcoming space.

Home in London

4.93 out of 5 average rating, 59 reviews

Upscale 2 bedroom hidden gem

Welcome to our 2 bedroom executive home close to 401/402 and Victoria hospital (5 minutes) Walk into brand new, lower level beautiful home. Large gourmet kitchen with island with plenty of room to work remotely with high speed wifi. Relax on our cosy sectional before retiring to our gorgeous bedrooms withTV/luxurious linens. Close to grocery/coffee shops/huge park with walking trails all within a 2 min walk. For pleasure or business we will make sure you have a 5 ⭐️ stay! on our cosy sectional

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Guest favorite

A well-lit living area features a dark sofa adorned with decorative pillows, accompanied by a stylish armchair. A coffee table sits in front, while large glass doors lead to a balcony, framed by light curtains. Art prints are displayed on the wall, enhancing the space.

Apartment in London

4.9 out of 5 average rating, 188 reviews

Charming 1 Bed Near Downtown

City of London Construction Notice: Potential for noise. Please see other details for more info Welcome to our charming 1-bed, 1-bath apt in the heart of downtown! All amenities, wifi, laundry, and Netflix included. The property backs onto the river with a beautiful trail behind the house. Enjoy the convenience of being near downtown London. Private balcony is great for relaxing while watching the sunset. 10-15 min walk to Budweiser Gardens, Downtown, and 5 min drive to Western University.

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Guest favorite

The exterior view showcases a two-story home with a combination of brick and stone accents. A well-maintained driveway leads to a parked vehicle, while large, arched windows allow natural light to brighten the entrance. The front porch features elegant columns, contributing to the home's welcoming appearance.

Guest suite in London

4.92 out of 5 average rating, 273 reviews

Modern Cozy Executive Suite with Private Entrance

Forget your worries in this spacious and serene space. Welcome to our cozy centrally located basement unit with a separate private entrance. This place is just 2-5 minutes away from walmart supercentre, No Frills Grocery, Winners, Homesense, Marshalls, the University Teaching Hosipital, the University of Western Ontario and many other places. The stylish unit is perfect for working individuals, and people seeking a comfortable private and convenient stay in a beautiful neighborhood.

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Top guest favorite

An open-concept living space features natural wood beams and a striking black accent wall. A round dining table is surrounded by four chairs, with a cozy seating area enhanced by a large beanbag. Decorative plants and stylish lighting fixtures add warmth to the environment.

Guesthouse in London

5.0 out of 5 average rating, 55 reviews

Stylish Private Loft | 1800s Farmhouse | Lake View

One-of-a-kind loft that sits inside a restored 1800s farmhouse with exposed beams, gas fireplace, and a sunroom with serene water view. Separate entrance, completely private unit — designed for the ideal getaway. King Endy bed with luxe cotton bedding, roomy bathroom with soaker tub. Nespresso, craft teas, induction stove. Hi-fi sound system, 55" 4K TV with Netflix and Prime. Sit/stand desk with Herman Miller chair. Minutes from the highway — peaceful, private, and unforgettable.

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Top guest favorite

Home in St. Thomas

5.0 out of 5 average rating, 61 reviews

lost + found under the pines

Lost + Found is a sanctuary for deep rest and connection, nestled among towering pines. This private retreat blends peace and modern comfort—a cozy living area with smart TV and Starlink Wi-Fi, a full kitchen stocked with spices, tea, coffee, and essentials, a spacious bath with shower, washer/dryer, and a comfortable queen bed. Outside, enjoy the fire pit, cozy hammock, Blackstone grill, electric barrel sauna, and free parking—come home to yourself.

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Top guest favorite

The kitchenette offers modern appliances, including a refrigerator and dishwasher, and features a long bar with three stools. A foosball table is positioned nearby, while large windows with horizontal blinds provide ample natural light.

Guest suite in London

4.91 out of 5 average rating, 224 reviews

West London Retreat with Hot Tub

Welcome to our retreat in west London! This stylish Two-Level Basement Split is a guest suite ideal for friends and families. Our 1+Den has 2 comfy Queen Beds, 1.5 bathrooms, a large kitchenette with every appliance you need, and a foosball table for some competitive fun. Outside, there's a hot tub, firepit (BYO wood), BBQ, and outdoor eating area. We live upstairs and are available to assist with the indoor or outdoor amenities at any time!

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Guest favorite

Tiny home in Granton

4.96 out of 5 average rating, 25 reviews

Smith's Den @ Smithden

Looking for northern ambience in a weekend getaway to relax and recharge, that won’t take hours to get to? Want to spend your time vacationing not commuting? Come enjoy a private, secluded, quiet getaway! Featuring miles of maintained walking trails, two ponds and a river running through with towering pines and gorgeous natural beauty, it’s a nature lovers paradise. In winter the trails are perfect for snowshoeing or cross-country skiing.

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Superhost

Home in London

5.0 out of 5 average rating, 7 reviews

Modern*2026 Build*TV75”*Sleeps10*Patio*Laundry

Welcome to our modern 4-bedroom home in peaceful Lambeth! Sleeps up to 10 guests with 6 beds (1 king, 2 queens, twin bunk, and sofa bed). Enjoy 3.5 bathrooms, a fully equipped kitchen, spacious living room, 75" Smart TV, fast Wi-Fi, dedicated workspace, washer/dryer, coffee station, private patio, fenced backyard, free parking, and dining for 10 with a table and kitchen island. Minutes from Hwy 401, shopping, restaurants, and downtown London.

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Superhost

A modern two-story home features a combination of brick and stucco exterior. Large windows offer a clear view of the spacious front yard and driveway. The entrance is highlighted by a covered porch, while a symmetrical layout adds to the home's elegant appearance.

Home in London

4.82 out of 5 average rating, 78 reviews

Luxury 5BR· Chef's Kitchen · Sleeps 10 · Superhost

⭐ Superhost · 100% Response Rate New build, 2024 · 3,500 sq ft of designer luxury for up to 10 guests · London, Ontarios finest estate home in prestigious Silver Leaf Estates. Whether you're planning a family reunion, corporate retreat, graduation celebration, golf getaway, or Western University visit — this is the only home in London, Ontario that delivers resort-calibre space, finishes, and hospitality at an Airbnb. .

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Top guest favorite

A hot tub is situated on a spacious deck surrounded by lush green trees, providing a serene forest backdrop. Nearby, a glass-top table with several chairs offers an inviting space for outdoor dining. Sunlight filters through the leaves, creating a calming atmosphere.

Home in Southwold

4.97 out of 5 average rating, 209 reviews

Nature Lover's Luxury Paradise

Nature Lover's Luxury Home in the woods. Creek's Edge Estate is a beautifully decorated home that is nestled on 10 acres of private woods. Minutes from London, ON this 4BDRM+3.5 BATH home sits next to some private hiking trails. Enjoy the sounds & sights of nature while relaxing in the hot tub. A beautiful escape for couples, families or groups looking to relax and recharge. Too many amazing amenities to list!

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Top guest favorite

A modern one-story unit is shown with a gray exterior and a white door. Large windows permit light into the space, enhancing the exterior's simple design. A neatly maintained garden surrounds the unit, adding greenery and a cozy atmosphere.

Guesthouse in London

4.97 out of 5 average rating, 152 reviews

Argyle Garden Suite: Patio and Garden areas

Welcome to the Argyle Garden suite. Located in historic east London, this sleek, modern newly constructed 1 bedroom unit was made with your comfort in mind. Rest easy in the queen-sized bed in the main bedroom overlooking the secret garden accessible by path on left of unit. The queen-sized pull-out sofa in the living room makes it perfect for families or up to 2 couples.

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