House vacation rentals in Middlesex County

Find and book unique houses on Airbnb

Top-rated house rentals in Middlesex County

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Superhost

A cozy living area features a queen bed with bright yellow bedding, complemented by a gray sofa with colorful cushions. A desk is positioned nearby, and a flat-screen TV is mounted on the wall. Decorative plants add a touch of color to the space.

Home in London

4.82 out of 5 average rating, 261 reviews

Amazing Cozy Fully Private Studio

It is a modern built unit in a quiet & lovely neighborhood. It is a big Livingroom attachd with private bathroom, a kitchenette with Fridge stocked with water, microwave, toaster, boiling kettle, Rice cooker, coffee maker stockd with coffee creamy. This is a 100% private place where you enjoyd your privacy. it has its own side entrance where you will climb a staircase down to the entranc door with a smart lock code, A/C, Fan & Fireplace. There is a smart TV with acces to Netflix, Youtube, IPTV

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Top guest favorite

A modern living area is presented with a gray leather sectional sofa, featuring decorative pillows and a bright throw. A wooden coffee table with magazines and a decorative bowl sits in front. Large windows allow natural light and reveal views of a green space outside.

Home in Southwold

4.97 out of 5 average rating, 155 reviews

New Home Sleeps 14, 6BR, BBQ, Games Room, Office

6 Bedrooms Near London, ON New 3400 sqft furnished designer home in the family neighborhood of Talbotville with convenience and comfort in mind! House has large private, fenced yard and backs on to a public park with playground, bball court, and soccer field. All new appliances and furniture. Includes spacious front office with doors for privacy, Fully stocked kitchen, 2 living rooms equipped with TV and PS3, Games Room, highspeed WiFi, and 4 bathrooms ensure a comfortable and relaxing stay.

ValueFamilyNearby

Superhost

A dining area is highlighted by a glass table adorned with a decorative bowl and fresh flowers. Dark walls are complemented by elegant white trim, and a vintage mirror reflects soft light. An artwork of a woman grace the wall, adding a touch of sophistication.

Home in London

4.92 out of 5 average rating, 296 reviews

Elegant 3-Bdr House| DT| Parking | 1.5 Gbps WiFi

Welcome to your dream escape in downtown London! This 1200+ sqft, 3-bdr bungalow blends historic charm with modern luxury. Renovated and steps from Victoria Park, Budweiser Gardens, Covent Garden Market, and vibrant shops & cafes. Enjoy strolls to top attractions in London. With UH, UWO, and Fanshawe C nearby, convenience is at your doorstep. This cozy retreat feels like home with stylish elegance. Perfect for a weekend getaway or extended stay. Book now for an unforgettable London experience!

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Guest favorite

A cozy living area is presented with a gray sofa and a black armchair, accompanied by a yellow ottoman at the center. Natural light filters in through the window with shutters, enhancing the warm wooden flooring and soft area rug beneath.

Home in London

4.92 out of 5 average rating, 115 reviews

Lovely charming 3 bedroom home

Welcome to our 3 bdrm/4 bed professionally cleaned home. Spacious kitchen/coffee bar. Two living rooms for larger groups with a smart TV. Luxurious linen/comfy beds. 1.5 washrooms dedicated workspace with wifi Beautiful backyard oasis Located 2 blocks from Vic Hospital. Everything is within walking distance, restaurants, drug stores, and grocery stores, Wortley Village has little shops/restaurants and coffee shops. whether you’re here for leisure or business we will make sure your trip is 5🌟

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Guest favorite

A well-lit living area featuring a cozy sofa and a small round table. A wall-mounted TV is visible, along with open shelves displaying decorative items. Windows with blinds allow natural light, while a desk and office chair provide a functional workspace.

Home in London

4.95 out of 5 average rating, 159 reviews

Welcome to your Serene Gateway!

A fully remodeled private basement unit. Your private Haven. Spacious, beautiful and clean studio in a quiet, beautiful, friendly and family oriented environment. minutes away from amenities like Tim Hortons, Bus stop, YMCA, masonville Shopping Mall and trails. 10 minutes drive to Western University, 11 minutes drive to Fanshawe College and 15 minutes drive to London ontario Downtown or Airport Need a hot drink, we offer a Keuring coffee maker with complimentary coffee pods, tea, suga etc

FamilyValueSolo travel

Guest favorite

The living room showcases a spacious gray sofa positioned around a round coffee table. A modern flat-screen TV is mounted on the wall, complemented by a sleek electric fireplace below. Large windows allow natural light to fill the space, revealing a peaceful outdoor view.

Home in London

4.92 out of 5 average rating, 170 reviews

4 Bedroom + 3.5 Bath + Close to Hwy/Dt/Boler Mt

Newly built and furnished designer home in the family neighborhood of Glendale with convenience and comfort in mind! Fully stocked kitchen, living room equipped with Samsung Smart TV (Netflix, Disney+, and more), super highspeed WiFi, and a modern designer bathroom ensures a comfortable and relaxing stay. Very close to the highway and just 10 minutes to Boler Mountain. 15-20 minutes to Western University and DT London. Easy access to city transportation makes this location a gem for anyone.

FamilyValueSleep quality

Guest favorite

A modern kitchen features sleek white cabinetry and stainless-steel appliances, including a refrigerator and oven. A spacious dark countertop extends to an island with seating for four. Recessed lighting illuminates the area, enhancing the contemporary design.

Home in St. Thomas

4.93 out of 5 average rating, 109 reviews

Luxurious Four Bedroom Home

Luxurious four bedroom home in the heart of St. Thomas. Located minutes from shopping, grocery stores, restaurants, Cineplex, Fit4Less, Tim Hortons and St. Thomas/Elgin Fanshawe College. You’ll immediately fall in love with my place because of the beautiful open concept living space fully loaded with brand new appliances for you and your group to use during your stay. My space features 4 comfortable queen beds, 2.5 washrooms, cable TV, fast Wi-Fi and parking for 4 vehicles.

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Top guest favorite

The charming exterior of the cottage features a covered wraparound porch adorned with hanging flower baskets. A well-kept lawn and garden enhance its appeal, while visible steps lead to the porch entrance. The roof is structured with a gable design, complemented by large windows for natural light.

Home in Port Stanley

4.99 out of 5 average rating, 175 reviews

Orchard Beach Boutique Cottage

**See note on guest maximum** Your family will be close to shopping, dining and fun when you stay at this home that’s hidden away, while in the center of everything. **Guest maximum of 4 does not include children under the age of 12, as per local municipal license approval** please help us adhere to our license rules, ask if you aren’t sure. Pet-friendly, well-appointed cozy cottage steps from the beach, shops and restaurants, with plenty of parking in the driveway.

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Guest favorite

The modern exterior of the detached house features a mix of textured stone and smooth stucco. Large windows allow for natural light, while the spacious driveway provides access to the attached garage. The elevated entrance is marked by steps leading to the front door.

Home in London

4.83 out of 5 average rating, 117 reviews

Amazing 6BR in London - Spacious Family Stay

Introducing our brand new 5BR, 5 full bath detached house in London. Enjoy its modern open-concept design flooded with natural light. The fully equipped kitchen, cozy family room with a large flat-screen TV, and high-speed internet ensure comfort and convenience. Located in a safe neighborhood with easy access to major highways, this home boasts comfortable bedrooms with high-quality linens and free parking. Your perfect haven awaits!

LocationFamilyTV

Top guest favorite

A hot tub is situated on a spacious deck surrounded by lush green trees, providing a serene forest backdrop. Nearby, a glass-top table with several chairs offers an inviting space for outdoor dining. Sunlight filters through the leaves, creating a calming atmosphere.

Home in Southwold

4.97 out of 5 average rating, 211 reviews

Nature Lover's Luxury Paradise

Nature Lover's Luxury Home in the woods. Creek's Edge Estate is a beautifully decorated home that is nestled on 10 acres of private woods. Minutes from London, ON this 4BDRM+3.5 BATH home sits next to some private hiking trails. Enjoy the sounds & sights of nature while relaxing in the hot tub. A beautiful escape for couples, families or groups looking to relax and recharge. Too many amazing amenities to list!

LocationFamilyNearby

Top guest favorite

A cozy living area features a comfortable seating arrangement with a mix of lounge chairs and a sectional sofa. A coffee table is centered on a soft area rug, while a TV is mounted above a white fireplace, surrounded by decorative plants and soft lighting.

Home in London

4.9 out of 5 average rating, 136 reviews

Cozy home on quiet mature street w/ outdoor space

Welcome to beautiful Byron! Steps away from Springbank Park, this cozy 2 bedroom + office sits on a mature, tree-lined street. 5 min walk to great local restaurants, Metro and LCBO. Features a fully fenced in backyard and three season sunroom. Access includes the main floor, backyard, driveway, patio & BBQ. Come see why Byron is THE best neighbourhood in the Forest City!

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Superhost

A bright living area features a dark grey sofa accented with decorative cushions. A circular glass coffee table occupies the center, surrounded by a light rug. Large windows are adorned with patterned curtains, allowing natural light to illuminate the space.

Home in London

4.79 out of 5 average rating, 107 reviews

Beautiful home in west of London

Enjoy the coziness of this newly renovated 2 storey home, with 3 bedrooms, 1.5 bathrooms in the west of London. This spacious and beautifully decorated property features new laminate wooden floors, new marble kitchen countertops and a large, and bright open concept kitchen/dining area. It has a great location with close proximity to Costco and all the necessary amenities.

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