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House vacation rentals in Middlesex County

Find and book unique houses on Airbnb

Top-rated house rentals in Middlesex County

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Superhost
A dining area is highlighted by a glass table adorned with a decorative bowl and fresh flowers. Dark walls are complemented by elegant white trim, and a vintage mirror reflects soft light. An artwork of a woman grace the wall, adding a touch of sophistication.
Home in London
4.92 out of 5 average rating, 298 reviews

Elegant Downtown 3BR Main-FL Home | Free Parking

Enjoy exclusive use of a bright, renovated 1,200+ sq. ft. main-floor residence in a detached bungalow near DT London. The home features 3 comfortable bedrooms, a fully equipped kitchen, a spacious living area, a full bathroom, in-unit laundry, keyless entry, speedy Wi-Fi, a 65-inch Roku TV, heating and AC, and free on-site parking. Steps from Victoria Park, Canada Life Place, Covent Garden Market, and vibrant shops & cafes. With UH, UWO, and Fanshawe C nearby, convenience is at your doorstep.

LocationFamilyTV

Guest favorite
A cozy living area is presented with a gray sofa and a black armchair, accompanied by a yellow ottoman at the center. Natural light filters in through the window with shutters, enhancing the warm wooden flooring and soft area rug beneath.
Home in London
4.92 out of 5 average rating, 115 reviews

Lovely charming 3 bedroom home

Welcome to our 3 bdrm/4 bed professionally cleaned home. Spacious kitchen/coffee bar. Two living rooms for larger groups with a smart TV. Luxurious linen/comfy beds. 1.5 washrooms dedicated workspace with wifi Beautiful backyard oasis Located 2 blocks from Vic Hospital. Everything is within walking distance, restaurants, drug stores, and grocery stores, Wortley Village has little shops/restaurants and coffee shops. whether you’re here for leisure or business we will make sure your trip is 5🌟

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Top guest favorite
A spacious two-story brick house is presented, featuring a large driveway and a well-maintained front lawn. The entrance is accented by a covered porch and double glass-paned doors. Large windows allow natural light to illuminate the front façade.
Home in London
4.93 out of 5 average rating, 231 reviews

Spacious 4-bdr+Study/UWO/Masonville/YMCA/N. London

Please read the full description and notes before making reservations. Forget your worries in this spacious and serene space. Enjoy the quiet and safe location yet convenient to everything. Minutes drive to Masonville Place, the biggest mall in north Londn, SilverCity London Cinemas, YMCA, Public Libraries, UWO, University Hospital, shopping plazas, grocery stores, restaurants & more! High ranking Jack Chambers Public School is in walking distance. Laundry on site. Free parking on premises.

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Guest favorite
A well-lit living area featuring a cozy sofa and a small round table. A wall-mounted TV is visible, along with open shelves displaying decorative items. Windows with blinds allow natural light, while a desk and office chair provide a functional workspace.
Home in London
4.95 out of 5 average rating, 161 reviews

Welcome to your Serene Gateway!

A fully remodeled private basement unit. Your private Haven. Spacious, beautiful and clean studio in a quiet, beautiful, friendly and family oriented environment. minutes away from amenities like Tim Hortons, Bus stop, YMCA, masonville Shopping Mall and trails. 10 minutes drive to Western University, 11 minutes drive to Fanshawe College and 15 minutes drive to London ontario Downtown or Airport Need a hot drink, we offer a Keuring coffee maker with complimentary coffee pods, tea, suga etc

LocationFamilyLong stay

Guest favorite
The living room showcases a spacious gray sofa positioned around a round coffee table. A modern flat-screen TV is mounted on the wall, complemented by a sleek electric fireplace below. Large windows allow natural light to fill the space, revealing a peaceful outdoor view.
Home in London
4.92 out of 5 average rating, 172 reviews

4 Bedroom + 3.5 Bath + Close to Hwy/Dt/Boler Mt

Newly built and furnished designer home in the family neighborhood of Glendale with convenience and comfort in mind! Fully stocked kitchen, living room equipped with Samsung Smart TV (Netflix, Disney+, and more), super highspeed WiFi, and a modern designer bathroom ensures a comfortable and relaxing stay. Very close to the highway and just 10 minutes to Boler Mountain. 15-20 minutes to Western University and DT London. Easy access to city transportation makes this location a gem for anyone.

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Superhost
Home in London
4.76 out of 5 average rating, 153 reviews

Entire Basement Unit (separate entrance)

Stunning Entire Basement Unit It’s separate entrance free 3 parking spaces on the property . The Basement has one room and two beds located 5 minutes away from U.W.O university 2 minutes away from shopping centres close to downtown as well … it has all the amenities that you can think of wifi , TV (Netflix), kitchen, free parking ,washer and dryer , stove, dishwasher, refrigerator, toaster, Keurig coffee machine,,microwave , and extra blankets and pillows, the list goes on and on.

LocationValueSolo travel

Guest favorite
A modern kitchen features sleek white cabinetry and stainless-steel appliances, including a refrigerator and oven. A spacious dark countertop extends to an island with seating for four. Recessed lighting illuminates the area, enhancing the contemporary design.
Home in St. Thomas
4.93 out of 5 average rating, 109 reviews

Luxurious Four Bedroom Home

Luxurious four bedroom home in the heart of St. Thomas. Located minutes from shopping, grocery stores, restaurants, Cineplex, Fit4Less, Tim Hortons and St. Thomas/Elgin Fanshawe College. You’ll immediately fall in love with my place because of the beautiful open concept living space fully loaded with brand new appliances for you and your group to use during your stay. My space features 4 comfortable queen beds, 2.5 washrooms, cable TV, fast Wi-Fi and parking for 4 vehicles.

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Top guest favorite
The charming exterior of the cottage features a covered wraparound porch adorned with hanging flower baskets. A well-kept lawn and garden enhance its appeal, while visible steps lead to the porch entrance. The roof is structured with a gable design, complemented by large windows for natural light.
Home in Port Stanley
4.99 out of 5 average rating, 177 reviews

Orchard Beach Boutique Cottage

**See note on guest maximum** Your family will be close to shopping, dining and fun when you stay at this home that’s hidden away, while in the center of everything. **Guest maximum of 4 does not include children under the age of 12, as per local municipal license approval** please help us adhere to our license rules, ask if you aren’t sure. Pet-friendly, well-appointed cozy cottage steps from the beach, shops and restaurants, with plenty of parking in the driveway.

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Guest favorite
A light-filled living room features two white sofas and a wooden coffee table at the center. A fireplace is located in the background, flanked by a television on the wall. Large windows provide a view of the outdoors, with gray curtains framing the space.
Home in London
4.93 out of 5 average rating, 174 reviews

Sleeps 14|Ping-Pong|BBQ|Fire Pit|ArcadeGames

Introducing our newly renovated 5 bedroom, 2 full bath detached house in London. Enjoy its fresh design flooded with natural light. The fully equipped kitchen, sprawling family rooms with a large flat-screen TV's, and high-speed internet ensure comfort and convenience. Located in a safe neighbourhood with easy access to major highways, this home boasts comfortable bedrooms with high-quality linens and free parking. Your perfect haven awaits!

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Guest favorite
The modern exterior of the detached house features a mix of textured stone and smooth stucco. Large windows allow for natural light, while the spacious driveway provides access to the attached garage. The elevated entrance is marked by steps leading to the front door.
Home in London
4.83 out of 5 average rating, 117 reviews

Amazing 6BR in London - Spacious Family Stay

Introducing our brand new 5BR, 5 full bath detached house in London. Enjoy its modern open-concept design flooded with natural light. The fully equipped kitchen, cozy family room with a large flat-screen TV, and high-speed internet ensure comfort and convenience. Located in a safe neighborhood with easy access to major highways, this home boasts comfortable bedrooms with high-quality linens and free parking. Your perfect haven awaits!

FamilyLocationSkiing

Top guest favorite
The exterior of a spacious, white home is showcased against a clear blue sky, surrounded by lush green trees. A large deck extends from the second floor, offering an outdoor space. The entrance features a wooden door, and a gravel driveway leads to the garage.
Home in Fingal
4.98 out of 5 average rating, 119 reviews

Port Talbot White House- With Pickleball Court!

Beautifully renovated 6000 square foot home nestled amongst the trees of the Port Talbot Estate. The White House has it all! A private Lake Erie beachfront (shared only with the other 2 cottages on the property,) endless hiking trails, beautiful cliff bluffs and a winding creek that's perfect for a morning canoe ride through the forest. Converted riding arena is now home to 2 pickleball courts as well as ample room for activities!

LocationFamilyNearby

Top guest favorite
A hot tub is situated on a spacious deck surrounded by lush green trees, providing a serene forest backdrop. Nearby, a glass-top table with several chairs offers an inviting space for outdoor dining. Sunlight filters through the leaves, creating a calming atmosphere.
Home in Southwold
4.97 out of 5 average rating, 212 reviews

Nature Lover's Luxury Paradise

Nature Lover's Luxury Home in the woods. Creek's Edge Estate is a beautifully decorated home that is nestled on 10 acres of private woods. Minutes from London, ON this 4BDRM+3.5 BATH home sits next to some private hiking trails. Enjoy the sounds & sights of nature while relaxing in the hot tub. A beautiful escape for couples, families or groups looking to relax and recharge. Too many amazing amenities to list!

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Popular amenities for Middlesex County house rentals