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Vacation rentals in Mesopotamia

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
The open-air living space features floor-to-ceiling glass doors that provide panoramic views of the surroundings. A vintage green coffee grinder is positioned prominently within the room. Natural light floods the space, illuminating the wooden beams of the ceiling and the elegant outdoor dining area.
Home in Fredonia
4.91 out of 5 average rating, 22 reviews

Hacienda Naya: The Hidden Coffee Paradise

Hacienda Naya: Where nature meets luxury. A 32-hectare retreat with coffee fields, waterfalls, and breathtaking views. Sleeps up to 13 guests. Relax by the private pool, unwind in total tranquility. Relax in the pool, enjoy a coffee tour, hike to Waterfalls or explore on horseback or ATV. Optional maid (COP 75,000/day) and Colombian cook (COP 120,000/day) for a seamless stay. Just 25 minutes from Fredonia, under two hours from Medellín. Escape, explore, indulge—your perfect getaway awaits.

Guest favorite
A charming wooden house is nestled among lush greenery, surrounded by trees. A covered balcony spans the front, offering outdoor seating. The entrance is marked by a pathway, with various plants and flowers enhancing the natural setting.
Cabin in Rionegro
4.95 out of 5 average rating, 129 reviews

cabaña paniym

Ven y disfruta de una estadía increíble con las personas que mas quieres o si eres una persona que viaja sola también es para ti... y llénate de naturaleza y tranquilidad en un lugar totalmente alejado del ruido donde también podrás trabajar con nuestro internet de alta velocidad y todas nuestras amenidades, como una cama super cómoda, cocina para que te inspires en ser el mejor chef y una bañera con agua caliente increíblemente relajante y como ves en las fotos los lugares al aire libre para ti

Top guest favorite
A modern cabin is positioned on a hillside, surrounded by lush greenery and offering panoramic views of the surrounding landscape, including a prominent rock formation and a serene body of water in the foreground.
Tiny home in Guatape
4.98 out of 5 average rating, 562 reviews

Foresta: Modern cabin with views of the rock

FORESTA is a modern cabin created with love for you to have an unforgettable stay in the middle of nature, with total comfort. Enjoy the privileged views from the deck, chill out in the jacuzzi, watch the dozens of birds that visit us or have a chat by the fireplace in the living room. FORESTA is a great launchpad to explore Guatape, climb the rock and do kayaking, jet-ski, wakeboard, sailing, paraglading, horseback riding, hiking, getting a helicopter ride or having an ATV tour. You choose!

Superhost
Tiny home in Cocorná
5 out of 5 average rating, 3 reviews

Cabin with jacuzzi, private river and natural pool

Enjoy incredible privacy in the beautiful nature of Cocorná. Relax in the jacuzzi or enjoy the beautiful river with a private terrace next to a naturally created pool that belongs exclusively to this property. The cabin features a beautiful bathroom, a king size bed, Wi-fi, a TV with Netflix, and a kitchen equipped with all cooking utensils including a barbecue. We also organize various activities including paragliding and rafting. We offer transportation. Breakfast is included! (to prepare)

Guest favorite
Home in Vereda El Penasco
5 out of 5 average rating, 5 reviews

Forest house - Just 25 minutes away from Poblado

Located in a private community, this house offers the perfect balance between nature and city convenience. • Beautiful city and mountain views with stunning sunsets • Bright, comfortable workspace, ideal for remote work • 300 Mb fiber internet + 200 Mb Starlink backup • Fully equipped kitchen with essentials • Washer and dryer included • Smart TV with Fire Stick + 135" proyector • Rappi delivers groceries and meals from local supermarkets and restaurants. • You can reach the house by Uber.

Guest favorite
A wooden hot tub is showcased in a bright space surrounded by green plants. The tub features two black headrests and water bubbles gently rising. Wooden steps lead up to the tub, enhancing the natural ambiance.
Apartment in Sabaneta
4.91 out of 5 average rating, 300 reviews

Terraza Privada con Jacuzzi y Vistas a la Montaña

¡Refugio Cielo Verde! Descubre un espacio encantador en Sabaneta, donde la tranquilidad y la comodidad se unen para brindarte una experiencia única. Cada rincón ha sido diseñado con amor y cuidado para brindarte una maravillosa experiencia. Disfruta de un jacuzzi privado en tu terraza con vistas a la montaña. Relájate con total privacidad, cocina equipada, WiFi rápido y todo lo necesario para una estancia inolvidable. Ideal para desconectar, reconectar y regalarte momentos especiales.

Top guest favorite
A small blue house features a welcoming porch supported by a vibrant blue railing. Decorative elements, including hanging items, add character to the exterior. Lush greenery surrounds the structure under a clear blue sky, enhancing the sense of natural tranquility.
Cottage in Medellín
4.97 out of 5 average rating, 160 reviews

Cottage and nature in Santa Elena

This little house in the natural reserve San Rafael, is a quiet place with a beautiful landscape, ideal for physical, emotional and spiritual renewal, and finding your harmony in connection with the trees, plants and soil. In the nature reserve you will be able to walk paths between the vegetation and the forest and you will find spaces for observation, contemplation and meditation. It is located very close to the Santa Elena park where you can find restaurants, markets, and crafts.

Guest favorite
Cabin in Rionegro
4.97 out of 5 average rating, 34 reviews

The Ultimate Group House w/ Hot Tub & Amazing View

About this space 🌟 2 bedrooms, each with a double bed & private bathroom 🛏️ Double sofa bed in the living room 🛋️ Bathrooms with hot water & fresh towels 🚿 Living room with Smart TV & WiFi 📺 Private jacuzzi for relaxation 💦 Fully equipped kitchen 👩‍🍳 Gas BBQ grill for cookouts 🍖 Catamaran net, dining table & spacious deck/terrace 🌞 Private parking space 🅿️ Portable heater available 🔥 Breakfast available upon request, prepared by our staff with extra cost 🍳

Top guest favorite
The cozy cabin is nestled in a lush green landscape, illuminated by warm outdoor lights. A wooden deck features comfortable seating, overlooking the serene surroundings. Large windows provide a glimpse of the interior, showcasing a warm and inviting space harmonized with nature.
Farm stay in Rionegro
4.95 out of 5 average rating, 280 reviews

Casa del Leñador | Secluded nature retreat

🪓 Retiro Cabin – Casa del Leñador es la casa de nuestros sueños. Una tiny home pequeña, acogedora y rodeada de naturaleza. El lugar perfecto para pasar unos días en pareja, un fin de semana en familia o trabajar remoto en un entorno sin distracciones. Despierta con el canto de los pájaros al amanecer y disfruta de una fogata en el deck al atardecer. En Retiro Cabin tendrás total independencia y una vista sin igual del campo en el oriente antioqueño.

Guest favorite
The cabin's exterior is highlighted by rich wooden siding and large glass doors, surrounded by tall trees and lush greenery. A wooden deck extends from the cabin, featuring a small seating area and natural elements that blend with the serene landscape.
Cabin in Rionegro
4.92 out of 5 average rating, 149 reviews

Manoah - Cabin en el bosque

Manoah es un lugar maravilloso para los que están buscando reconectarse con la naturaleza y la serenidad de las montanas. Esta cabin es ideal para escapar del ruido de las ciudades y compartir unas acogedoras noches bajo las estrellas rodeado de Eucaliptos. con una vista inmejorable, algunas de nuestras comodidades incluyen un Jacuzzi y un horno para Pizzas, que seguramente harán que tengas la perfecta escapada.

Top guest favorite
Chalet in Antioquia
4.96 out of 5 average rating, 286 reviews

Cabaña Con Jacuzzi a 8 min del Aeropuerto JMC

Bienvenido a Quimera Ecolodge, un encantador chalet ubicado en un paraíso natural a tan solo 10 minutos del Aeropuerto José María Córdova. En Quimera Ecolodge, cada rincón ha sido diseñado para ofrecerte una experiencia única, combinando comodidad, sostenibilidad y una conexión auténtica con el entorno natural, ideal para quienes desean escapar del bullicio de la ciudad sin perder la cercanía a la comodidad.

Superhost
An outdoor terrace is revealed, surrounded by lush greenery and distant mountains. String lights cast a warm glow, illuminating a dining area with wooden tables and chairs. The open layout connects to an indoor space featuring a kitchen visible through large glass doors.
Cabin in Santa Elena
4.92 out of 5 average rating, 106 reviews

Cabaña Roble - Un refugio en el bosque

Estamos ubicados en un bosque nativo de robles en la vereda El Plan, cerca Medellin. La cabaña tipo loft de 50m2 que se funde con la naturaleza en un lote privado de 2 cuadras. Vive este lugar mágico con aire puro, fogatas al aire libre, caminatas y reconexión. Cerca de la cabaña encontrarán una panadería deliciosa, cultivos de verduras orgánicos, restaurantes y estrechas calles para caminar y recorrer.

Popular amenities for Mesopotamia vacation rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia