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Vacation rentals in Mesopotamia

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A charming wooden house is nestled among lush greenery, surrounded by trees. A covered balcony spans the front, offering outdoor seating. The entrance is marked by a pathway, with various plants and flowers enhancing the natural setting.
Cabin in Rionegro
4.95 out of 5 average rating, 129 reviews

cabaña paniym

Ven y disfruta de una estadía increíble con las personas que mas quieres o si eres una persona que viaja sola también es para ti... y llénate de naturaleza y tranquilidad en un lugar totalmente alejado del ruido donde también podrás trabajar con nuestro internet de alta velocidad y todas nuestras amenidades, como una cama super cómoda, cocina para que te inspires en ser el mejor chef y una bañera con agua caliente increíblemente relajante y como ves en las fotos los lugares al aire libre para ti

Top guest favorite
A modern cabin is positioned on a hillside, surrounded by lush greenery and offering panoramic views of the surrounding landscape, including a prominent rock formation and a serene body of water in the foreground.
Tiny home in Guatape
4.98 out of 5 average rating, 562 reviews

Foresta: Modern cabin with views of the rock

FORESTA is a modern cabin created with love for you to have an unforgettable stay in the middle of nature, with total comfort. Enjoy the privileged views from the deck, chill out in the jacuzzi, watch the dozens of birds that visit us or have a chat by the fireplace in the living room. FORESTA is a great launchpad to explore Guatape, climb the rock and do kayaking, jet-ski, wakeboard, sailing, paraglading, horseback riding, hiking, getting a helicopter ride or having an ATV tour. You choose!

Superhost
Tiny home in Cocorná
5 out of 5 average rating, 3 reviews

Cabin with jacuzzi, private river and natural pool

Enjoy incredible privacy in the beautiful nature of Cocorná. Relax in the jacuzzi or enjoy the beautiful river with a private terrace next to a naturally created pool that belongs exclusively to this property. The cabin features a beautiful bathroom, a king size bed, Wi-fi, a TV with Netflix, and a kitchen equipped with all cooking utensils including a barbecue. We also organize various activities including paragliding and rafting. We offer transportation. Breakfast is included! (to prepare)

Guest favorite
A wooden hot tub is showcased in a bright space surrounded by green plants. The tub features two black headrests and water bubbles gently rising. Wooden steps lead up to the tub, enhancing the natural ambiance.
Apartment in Sabaneta
4.91 out of 5 average rating, 300 reviews

Private Terrace with Jacuzzi and Mountain View

Cielo Verde Shelter! Discover a lovely space in Sabaneta, where tranquility and comfort come together to provide you with a unique experience. Every corner has been designed with love and care to provide you with a wonderful experience. Enjoy a private jacuzzi on your terrace with mountain views. Relax in total privacy, with a fully-equipped kitchen, fast WiFi, and everything you need for an unforgettable stay. Ideal for disconnecting, reconnecting and giving you special moments.

Top guest favorite
A small blue house features a welcoming porch supported by a vibrant blue railing. Decorative elements, including hanging items, add character to the exterior. Lush greenery surrounds the structure under a clear blue sky, enhancing the sense of natural tranquility.
Cottage in Medellín
4.97 out of 5 average rating, 160 reviews

Cottage and nature in Santa Elena

This little house in the natural reserve San Rafael, is a quiet place with a beautiful landscape, ideal for physical, emotional and spiritual renewal, and finding your harmony in connection with the trees, plants and soil. In the nature reserve you will be able to walk paths between the vegetation and the forest and you will find spaces for observation, contemplation and meditation. It is located very close to the Santa Elena park where you can find restaurants, markets, and crafts.

Guest favorite
Cabin in Rionegro
4.97 out of 5 average rating, 34 reviews

The Ultimate Group House w/ Hot Tub & Amazing View

About this space 🌟 2 bedrooms, each with a double bed & private bathroom 🛏️ Double sofa bed in the living room 🛋️ Bathrooms with hot water & fresh towels 🚿 Living room with Smart TV & WiFi 📺 Private jacuzzi for relaxation 💦 Fully equipped kitchen 👩‍🍳 Gas BBQ grill for cookouts 🍖 Catamaran net, dining table & spacious deck/terrace 🌞 Private parking space 🅿️ Portable heater available 🔥 Breakfast available upon request, prepared by our staff with extra cost 🍳

Top guest favorite
A single-story house surrounded by lush greenery is showcased. The exterior features a welcoming porch with seating and a hammock. The structure boasts large windows for natural light, while landscaped bushes and trees frame the property, enhancing the serene rural setting.
Farm stay in El Carmen de Viboral
4.97 out of 5 average rating, 100 reviews

☼♥Villa Serena ♥☼ 360° Views-Nature-Serenity

* An incredible house with gorgeous 360° views* * 143 m² / 1539 ft² house size * Private Deck. Views of valley/Rionegro/Airport * Views of mountains * Privacy gate. Alarm. Parking for 5+ Cars * Fully stocked and equipped kitchen * 1 km / 0.6-mile dirt road to the house (any car will access) * There are two homes on the property, the main, larger house is Villa Serena where you will stay, the second home has a separate entrance and is not offered in Airbnb.

Top guest favorite
The cozy cabin is nestled in a lush green landscape, illuminated by warm outdoor lights. A wooden deck features comfortable seating, overlooking the serene surroundings. Large windows provide a glimpse of the interior, showcasing a warm and inviting space harmonized with nature.
Farm stay in Rionegro
4.95 out of 5 average rating, 280 reviews

Lumberjack's House | Secluded nature retreat

🪓 Retreat Cabin – Lumberjack's House is our dream home. A small, cozy tiny home surrounded by nature. The perfect place to spend a few days as a couple, a family weekend or work remote in a distraction-free environment. Wake up to the singing of the birds at sunrise and enjoy a fire on the deck at sunset. In Retiro Cabin you will have total independence and an unparalleled view of the countryside in the Antioquia East.

Top guest favorite
Chalet in Antioquia
4.96 out of 5 average rating, 286 reviews

Cabin with Jacuzzi 8 min from JMC Airport

Welcome to Quimera Ecolodge, a charming chalet located in a natural paradise paradise just 10 minutes from José María Córdova Airport. At Quimera Ecolodge, every corner has been designed to offer you a unique experience, combining comfort, sustainability, and an authentic connection with the natural environment, ideal for those who want to escape the hustle and bustle of the city without losing proximity to comfort.

Guest favorite
The cabin's exterior is highlighted by rich wooden siding and large glass doors, surrounded by tall trees and lush greenery. A wooden deck extends from the cabin, featuring a small seating area and natural elements that blend with the serene landscape.
Cabin in Rionegro
4.92 out of 5 average rating, 149 reviews

Manoah - Cabin in the woods

Manoah es un lugar maravilloso para los que están buscando reconectarse con la naturaleza y la serenidad de las montanas. Esta cabin es ideal para escapar del ruido de las ciudades y compartir unas acogedoras noches bajo las estrellas rodeado de Eucaliptos. con una vista inmejorable, algunas de nuestras comodidades incluyen un Jacuzzi y un horno para Pizzas, que seguramente harán que tengas la perfecta escapada.

Top guest favorite
A spacious studio apartment is shown with a comfortable bed adorned with a soft gray throw. A dining table is positioned nearby, and a well-equipped kitchen is visible in the background with a refrigerator and stylish cabinetry.
Apartment in Rionegro
4.96 out of 5 average rating, 215 reviews

Comfortable studio apartment in Rionegro

Comfortable, fully-equipped studio apartment located in downtown Rionegro, in the Tres Cantos residential area, a quiet place for your rest and comfort, just a 10-minute walk from the town's main park, 5 minutes from the San Nicolás shopping center, and 20 minutes from José Maria Cordoba International Airport. Nearby are bus stops, supermarkets, shops, shopping malls, and restaurants.

Superhost
An outdoor terrace is revealed, surrounded by lush greenery and distant mountains. String lights cast a warm glow, illuminating a dining area with wooden tables and chairs. The open layout connects to an indoor space featuring a kitchen visible through large glass doors.
Cabin in Santa Elena
4.92 out of 5 average rating, 106 reviews

Cabaña Roble - A forest retreat

We are located in a native oak forest in the village of El Plan, near Medellin. The 50m2 loft-style cabin that blends with nature on a private 2-block lot. Experience this magical place with fresh air, outdoor fire pits, hiking, and reconnection. Near the cabin you will find a delicious bakery, organic vegetable crops, restaurants, and narrow streets for walking and exploring.

Popular amenities for Mesopotamia vacation rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia