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Vacation rentals in Mesopotamia

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
Cabin in Rionegro
4.85 out of 5 average rating, 95 reviews

The Ultimate Group House w/ Hot Tub & Amazing View

About this space 🌟 2 bedrooms, each with a double bed & private bathroom 🛏️ Double sofa bed in the living room 🛋️ Bathrooms with hot water & fresh towels 🚿 Living room with Smart TV & WiFi 📺 Private jacuzzi for relaxation 💦 Fully equipped kitchen 👩‍🍳 Ninja Foodi electric grill for cookouts 🍖 Catamaran net, dining table & spacious deck/terrace 🌞 Private parking space 🅿️ Portable heater available 🔥 Breakfast can be ordered via Rappi (delivery app). We can assist with your order 🍳

Top guest favorite
Tiny home in Cocorná
5 out of 5 average rating, 61 reviews

lovely cabin with sauna, jacuzzi and private river

Enjoy the beautiful nature and tranquility of this luxurious accommodation with a sauna, jacuzzi, and private river terrace. Just 75 minutes from Medellín, this beautiful cabin is easily accessible by any car or motorcycle. The spectacular surroundings of Cocorná have much to offer, including paragliding, rafting, quad biking, and hiking trails along beautiful rivers. We are happy to assist you with transport or activities. We offer private transport from the airport! Includes breakfast!

Top guest favorite
Farm stay in Rionegro
4.95 out of 5 average rating, 124 reviews

Gardener's House | Private nature retreat

🌸 Welcome to Retiro Cabin – Casa del Jardinero, the country house to fill with stories, where before escaping, we invite you to return to what our mind always longs for: nature. Casa del Jardinero de Retiro Cabin is the perfect place for a few days of rest with family or friends, to live a season in the countryside or to work remotely in an environment without distractions. At Retiro Cabin you will have independence and an unparalleled view of the countryside in eastern Antioquia.

Guest favorite
Cabin in El Carmen de Viboral
4.92 out of 5 average rating, 78 reviews

Espi Ritual

Step into tranquility and reconnect with nature in this serene Llano Grando cabin. Soak up the patio sun, immerse yourself in the beautiful garden, or spot countless bird species on the sun-deck overlooking the pond. This cabin is equipped with WiFi, a full kitchen, an asador, and a private entrance. The perfect location for a peaceful solo trip, charming romantic getaway, or unique family adventure. 15 minutes from charming San Antonia and near restaurants and shopping

Top guest favorite
Cabin in Rionegro
5 out of 5 average rating, 43 reviews

Selvva suites | luxury cabin in a forest + jacuzzi

Escape to SELVVA SUITES, a luxury retreat immersed in the tranquility of a native forest, just 50 minutes from Medellín. Located on the Llanogrande–La Ceja road, only 15 minutes from Llanogrande mall and 20 minutes from JMC Airport in Rionegro. Enjoy a King-size bed and a private jacuzzi surrounded by nature. Private parking with easy access for any type of vehicle. ⚠️ ✈️We are in an area with air traffic, and airplane noise can be heard. 🐾 Pet friendly

Top guest favorite
A modern structure emerges from lush greenery, framed by vibrant plants and a manicured lawn. Large glass doors lead to a spacious deck, offering a view of the mountains and a colorful sky. Pathway stones create a welcoming entrance.
Home in La Ceja
4.95 out of 5 average rating, 59 reviews

Country house, excellent location, beautiful view!

We invite you to enjoy a beautiful space surrounded by nature, with all the comforts you need to relax and unwind. You will feel like you are right at home. Ideal place for teleworking (digital nomads) and long stays. Just 10 minutes from La Ceja, 45 minutes from the international airport, and 1 hour from Medellín. Pets are welcome. Additionally, we offer yoga classes, Ayurvedic therapies (Abhyanga/Swedana), and tennis lessons. Perfect place for "slow" tourism!

Superhost
A modern cabin with a unique arched design is set against a vibrant sunset sky. The entrance features large glass doors framed by black accents, while the surrounding landscape showcases rolling hills that extend into the distance.
Cabin in La Ceja
4.85 out of 5 average rating, 55 reviews

Almost Heaven! Heaven's Edge

Nestled 7,000 feet high, our tranquil cabin promises breathtaking mountain and waterfall vistas. This retreat, perfect for romantic getaways or family escapades, enchants with its warming fire pit and rejuvenating hot tub. Experience the stunning wilderness, bask in the magnificent scenery, and craft unforgettable memories. This is not just a stay, but an experience enveloped in serene beauty, embracing the extraordinary amidst the ordinary. (500 characters)

Top guest favorite
A private terrace features a softly illuminated jacuzzi, surrounded by wooden decking, offering expansive views of the city at night. The structure includes large glass doors, enhancing visibility to the inside space while creating a seamless transition between indoor and outdoor areas.
Cabin in Sabaneta
4.95 out of 5 average rating, 161 reviews

eDeensabaneta Ibiza cabin

Este alojamiento único tiene personalidad propia. Disfruta de unas vistas increíbles en la terraza mientras te relajas en el jacuzzi, o disfruta de la acogedora cabaña en una zona muy próxima a sabaneta con la atención que tú te mereces. Esta cabaña hace parte de un sueño familiar llamado eDeen, donde nuestra prioridad es que cada momento sea único, brindando la mejor atención de manera personalizada para que los huéspedes se sienta como en casa.

Guest favorite
Farm stay in Cocorná
4.98 out of 5 average rating, 52 reviews

Bali-style cabin with forest and private river

Bali-style cabin with more than 2 hectares of private forest and river, hot Jacuzzi, wifi, spring climate, combining luxury and nature, deck next to the river, campfire, cinema-type video projector, shower with a view of nature, work and reading area, beautiful night lighting, kitchen and BBQ area, sun loungers and many other details designed to give you a unique experience and invite you to slow down and reconnect with yourself and nature

Top guest favorite
Cabin in Rionegro
4.98 out of 5 average rating, 128 reviews

Nature & View | Cabin with Jacuzzi and Nature

Enjoy an unforgettable experience in our private cabin, located just 8 minutes from José María Córdova International Airport. Enjoy a panoramic view of the city and relax in your private Jacuzzi. The cabin is equipped with a full kitchen, fast wifi, workspace and self check-in. You will find several nearby restaurants with home delivery, and inside the accommodation we have drinks and snacks to buy. 🚘 Trusted Uber driver

Top guest favorite
A single-story house surrounded by lush greenery is showcased. The exterior features a welcoming porch with seating and a hammock. The structure boasts large windows for natural light, while landscaped bushes and trees frame the property, enhancing the serene rural setting.
Farm stay in El Carmen de Viboral
4.97 out of 5 average rating, 109 reviews

☼♥Villa Serena ♥☼ 360° Views-Nature-Serenity

* An incredible house with gorgeous 360° views* * Private Deck. Views of valley/Airport * Mountain views * Privacy gate. Alarm. Parking for 2 Cars * Fully stocked and equipped kitchen * 1 km / 0.6-mile dirt road to the house (any car will access) * There are two homes on the property, the main, larger house is Villa Serena where you will stay, the second home has a separate entrance and is not offered in Airbnb.

Guest favorite
Villa in La Ceja
5 out of 5 average rating, 10 reviews

Family farm in La Ceja with a beautiful view and fireplace

Enjoy this charming country villa in La Ceja, ideal for families. Surrounded by nature and boasting stunning views, it offers 4 bedrooms plus a utility room, spacious gardens, an equipped kitchen, a fireplace, a double-height living room, and bright social areas. It has a kiosk with a barbecue area. It's the perfect place to relax, spend time with family or friends in a natural, safe and exclusive setting.

Popular amenities for Mesopotamia vacation rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia