Places to stay near Matthaei Botanical Garden

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Top-rated vacation rentals near Matthaei Botanical Garden

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Guest favorite
The bedroom features a queen bed with clean linens and two nightstands with lamps. A leather recliner is positioned nearby. A full-length mirror leans against the wall, and an abstract artwork decorates the space. Soft carpet covers the floor.
Guest suite in Ypsilanti
4.95 out of 5 average rating, 240 reviews

SoH Private Guest Suite (Separate Bath, Entrance)

New 2025 Upgrades—Super clean & cozy private suite carved out of our 2022 built home in a safe, serene subdivision w/ premium amenities. ✅Private Entrance & Contactless Check-In. 🚭 Smoke & pet 🐶 free. Features: -Private full bath 🛀 + bidet -Leather recliner -Snack/laptop table -Fast WiFi -55” LG 4K Smart 📺 -Massage gun -HEPA air purifier -☁️ fall humidifier/diffuser -reversible 🔥🧊 ceiling fan -Toiletries 🧼 🧴 -Kitchenette & ☕️/🫖 bar -Expandable mobile dining table/workstation -🧺 service & more

Top guest favorite
Home in Ann Arbor
4.98 out of 5 average rating, 130 reviews

Relaxing 3BR Ann Arbor Retreat – Near U of M & EMU

Relax to the max at this centrally-located home in a quiet, family-friendly neighborhood in Ann Arbor. Conveniently located just off US-23, between the University of MI, Eastern Michigan U & Trinity Hospital. Multiple restaurants and shopping are just a few blocks away. Inside, you will find a generously sized kitchen & oversized table in the huge dining room which opens onto a patio & large fenced yard. Sprawl out in the huge basement where there's a rec room, work station & laundry facilities.

Top guest favorite
Home in Ypsilanti
4.98 out of 5 average rating, 265 reviews

Secluded home-away-from-home with a cook's kitchen

Unwind at this renovated mid-century home, Hillside Manner. It is surrounded by woods, so feels private. You can eat in the cathedral dining area, or on the back patio in the warmer seasons. The mattresses & pillows are memory foam, the Amazon Smart TV is connected to Wi-Fi, and the large kitchen offers anything you need. Perfect for families and groups of friends, the 3 bdrms can sleep up to 6 guests. *Host occupies first floor apartment, which is totally separate. No parties of more than 10!

Guest favorite
A bright bedroom features hardwood flooring and a large window with plaid curtains that allow natural light to fill the space. A spacious bed with a light green coverlet is positioned against the wall, complemented by a simple desk and comfortable chair.
Guest suite in Ypsilanti
4.87 out of 5 average rating, 164 reviews

Full floor of Cozy Walkout Basement, close to i-94

Cozy up in the charming and woodsy elegance of this sparkling clean and peaceful living space. With easy access to I-94 entrance, it is 20 mins to DTW airport, 5 minutes to Ann Arbor, 10 min to U of M and EMU. The neighborhood is safe, secluded and full of natural sounds. Enjoy the private walk-out basement with spacious living space and large eastern-facing doors against a luscious and green backyard for the bright and peaceful mornings as you sip your warm coffee. (Free street parking)

Top guest favorite
Apartment in Ann Arbor
4.97 out of 5 average rating, 271 reviews

Downtown Delight ! Cozy 1 bedroom Apartment

Enjoy a stylish experience at this centrally-located apartment. Not only is this apartment Cozy, luxurious and offers everything you need to be comfortable, it is located in the heart of the Old West Side, minutes from Kerry town and downtown Ann Arbor's shops and restaurants! Walking distance to University of Michigan hospital and Campus, as well as experiencing all that the beautiful Huron river has to offer: Argo Park beautiful hiking, bike/running trails, canoeing and rapid water tubing.

Top guest favorite
Guest suite in Ann Arbor
4.96 out of 5 average rating, 105 reviews

Spacious Studio Suite with Private Entrance

Enjoy a clean & newly renovated private guest suite on Ann Arbor’s vibrant northwest side. Just a 5 minute drive from downtown (1.7 mi) and Michigan Stadium (2.1 mi), you’re perfectly positioned to explore! Walk to many West-Side restaurants and shops, or hop on public transit for easy access to downtown and all the city has to offer. A few businesses within walking distance include Plum Market, Aldi, LA Fitness, Homes Brewery, Ricewood BBQ, Knights Steakhouse, and Zingerman's Roadhouse.

Guest favorite
The living area is characterized by exposed brick walls and large windows that allow natural light. A comfortable sofa with patterned cushions is complemented by a round coffee table. A television is mounted on the wall, and decorative elements add warmth to the space.
Apartment in Ypsilanti
4.81 out of 5 average rating, 119 reviews

Thompson & Co Brick Loft KING

You will love this bright loft with 360 degrees of exposed brick, 12 foot ceilings, and large windows! Great night life downstairs Wednesday - Saturday. If you are a lights sleeper, this is not the listing for you! Just steps from Hyperion Coffee, Thompson Co., Aubree’s pizza and so many other great spots! This loft is a brand new space set in a historic building that was originally a hotel in 1839, then barracks used for the civil war in 1862. Come be a part of this amazing history!

Top guest favorite
The exterior of a modern, custom-designed home is showcased, featuring a combination of light-colored walls and stone accents. A winding path leads to the entrance, surrounded by neatly trimmed greenery and trees. Scenic views of the natural landscape create a serene backdrop.
Home in Ann Arbor
4.99 out of 5 average rating, 180 reviews

Huron River Lodge

Custom designed, private home featuring scenic views in a retreat like setting nestled along the Huron River just minutes from downtown Ann Arbor. The luxurious, light-filled space boasts two decks, hot tub, fully equipped kitchen, fireplace, and EV charging. This very special property is located along the Border-to-Border Trail and Amtrak line just minutes from US-23, M-14, and US-94. Immerse yourself in a unique environment of beauty and convenience with amenities for all seasons.

Top guest favorite
A spacious living area is visible, featuring a dark sectional sofa and two wooden bar stools at a kitchen island. Natural light filters through large windows. A rug adds warmth to the hardwood floor, while a potted plant and lamp decorate a wooden table.
Apartment in Ypsilanti
4.97 out of 5 average rating, 239 reviews

Beautiful, Well Designed, Sunny Apartment

This beautifully designed and decorated apartment is attached to, but separated, from a ranch style home in a residential neighborhood near the campuses of The University of Michigan and Eastern Michigan University. It includes 1 bedroom, 1 full bath, a full kitchen, a laundry room, a deck with patio furniture, and a parking space. There is a separate entrance and an exquisite backyard. Located near bus route and major arteries. Discounts are given for week and month stays.

Top guest favorite
The charming farmhouse features a neat exterior with white siding and a welcoming front porch. Rocking chairs are positioned for relaxation, while a landscaped garden with flowering plants enhances the front yard. Large windows allow natural light to fill the interior spaces.
Home in Ann Arbor
4.98 out of 5 average rating, 152 reviews

Nature-Filled Family Farm Retreat Near Ann Arbor

Escape to a peaceful, family-friendly farm retreat just outside Ann Arbor — a place designed for connection, comfort, and outdoor fun. This spacious home comfortably sleeps up to 10 guests, offers over 2,600 sq ft of indoor living space, and sits on approximately 2 acres of open grassy land to explore. Ideal for extended families, multi-family trips, group of friends and University of Michigan visits, this is more than a place to stay — it’s a setting where memories are made.

Guest favorite
The exterior of a brick home is displayed, featuring a covered entrance with a white door and two large windows. A well-maintained lawn surrounds the house, which is accented by natural stone landscaping elements and greenery. The inviting façade is complemented by a multi-toned siding.
Home in Ann Arbor
4.84 out of 5 average rating, 394 reviews

Quiet fully equipped near the heart of Ann Arbor

You will enjoy relaxing and making memories in our clean updated home just miles from the best shopping and dining in the city. Our 3 bedroom 1.5 bath home is stocked with all the conveniences of your very own home. Perfect for a couples trip, family vacation or extended stay. Nestled in a quiet neighborhood steps from a major bus route you will wake rested ready to spend the day enjoying Ann Arbor. Easy access to the stadium, campus and both major hospitals.

Top guest favorite
A softly decorated bedroom features light purple walls and white wooden floors. A spacious bed with coordinating bedding is positioned against one wall. Nearby, a white dresser is complemented by a decorative chair and a window with sheer curtains, allowing natural light to enter the room.
Home in Ypsilanti
4.93 out of 5 average rating, 112 reviews

Walkable Historic Shotgun Home w/ Parking & Yard

Recently renovated historic home 2 blocks from EMU's campus, and a short walk to the shops and restaurants in Depot Town and along Michigan Ave. Short commute to Ann Arbor, UM, Ford Lake, and area hospitals. Pet friendly with private fenced yard. Bags, treats, and bowls provided in pet station. Great walkies for both doggos and humans in the adjacent historic neighborhoods and EMU, or nearby nature trails. Off street parking for 1 car.

Popular amenities for vacation rentals near Matthaei Botanical Garden