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Guesthouse vacation rentals in Madre de Dios

Find and book unique guesthouse rentals on Airbnb

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Vacation rentals for every style

Get the amount of space that is right for you

Popular amenities for Madre de Dios guesthouse rentals

Kitchen
Wifi
Free parking on premises
Air conditioning

Family-friendly guest house rentals

A simple room is depicted, featuring a wooden ceiling and a ceiling fan. A wooden closet with drawers is visible, along with an open door leading to another space. Natural light enters through a window on the opposite wall.
Private room in Puerto Maldonado

Habitaciones en Puerto Maldonado

A modern structure featuring large glass windows that provide ample natural light and views of the surrounding greenery. Steps lead from the grassy area to the entrance. The landscape includes blooming flowers and trees, contributing to a peaceful ambiance.
Private room in Calca

HananPacha-Ashram Transpersonal

A bright room features large windows with flowing curtains, allowing natural light to illuminate the space. A spacious bed is adorned with a vibrant floral blanket. Minimalist furnishings, including a small table and chairs, are positioned at the far end, offering a tranquil atmosphere.
Private room in Puerto Maldonado
4 out of 5 average rating, 4 reviews

Habitaciónes comodas seguras y amplias

A spacious room features wooden beams across the ceiling and a parquet floor. A round table with a white tablecloth and four black chairs is present, alongside a bed with colorful blankets. A large window invites natural light, with a door leading to another area.
Private room in Calca

Casa de sanación NuNaTiKaY

A spacious bedroom is highlighted by a large, upholstered bed with crisp white linens and decorative pillows. Bright floral murals adorn the walls, complemented by wooden furniture, including a small desk and a chair. A glass door leads to an adjoining area, enhancing the open layout.
Private room in Urubamba

¡tu casa lejos de tu casa!

A spacious bedroom is furnished with a bed covered in a striped blanket. A wooden table is positioned nearby, and a television is mounted on the wall. Light hardwood flooring and pale walls create a bright and open feel.
Private room in Tambopata

Alquilo habitaciones amobladas

A pathway leads through a garden towards a two-story house, flanked by vibrant green plants and blooming flowers. Sunlight filters through the wooden balconies, enhancing the natural beauty of the setting. The surrounding mountains provide a serene backdrop.
Private room in Urubamba

Yogis House Urubamba

A cozy room features a spacious bed with a colorful blanket. Natural light enters through the large window, revealing views of the surrounding mountains. The walls are painted in a warm pink, and a bedside table is adorned with a small vase and a lamp.
Private room in Ollantaytambo

Habitación Matrimonial Vista a la Montaña

Guest house rentals with a patio

Natural light fills the room through a large window overlooking a palm tree. A simple bed is positioned against one wall. Light-colored curtains frame the window, and wooden flooring extends across the space, enhancing the bright atmosphere.
Private room in Tambopata
4.75 out of 5 average rating, 8 reviews

Private room + bathroom w/ shared spaces

A colorful promotional flyer showcases an exploration tour of Manu National Park. Highlights include bird watching, jungle hikes, hot springs, and river swimming, along with accommodations detailed for a comfortable stay. Images of lush greenery and wildlife are presented, promoting an immersive rainforest experience.
Guesthouse in C.p Salvacion

Coco's House

A warm-hued room features a spacious bed adorned with a colorful, fringed throw. A small bedside table sits next to the bed, complemented by a decorative vase. Textured wall accents add character, while soft natural light filters in through the window.
Private room in Calca

Room 2 in Beautiful Guest House

Superhost
A well-lit room features two spacious beds with colorful bed coverings. Natural light pours in through two large windows, while a wooden cabinet and a simple nightstand provide functional storage. The light walls and stone accents create a cozy atmosphere.
Private room in Urubamba

espacio tranquilo familiar

A spacious living area features two large sofas and a sectional, arranged around a coffee table. Natural light enters through several windows. A dining table with chairs is visible, along with a cozy rug and decorative plants accentuating the rustic charm.
Guesthouse in Urubamba

House Accommodation Valle Sagrado Urubamba Cusco

Guest favorite
The vibrant exterior of the eco lodge is adorned with colorful murals, surrounded by lush greenery and flowering plants. A wooden picnic table and a tall stool are placed on a manicured lawn, framed by trees and the distant mountains in the background.
Private room in Ollantaytambo
4.92 out of 5 average rating, 26 reviews

Full Moon Eco Lodge: Chaska 3

A minimalist bedroom features a spacious bed with a chocolate brown headboard and crisp white linens. A small desk is positioned against the wall, and a wall-mounted television is visible. Natural light filters through sheer curtain panels, enhancing the room's bright appearance.
Private room in Ollantaytambo
4.67 out of 5 average rating, 3 reviews

Casa Esteves: Encanto en Ollanta

A charming cobblestone pathway is flanked by yellow-walled buildings with rustic stone bases. Wooden doors, framed with potted plants, lead into each unit. Bright sunshine and a clear blue sky create a warm ambiance, while vibrant flowering vines add a touch of color.
Private room in Ollantaytambo

"Nicolasa Wasi"

Other guesthouse vacation rentals

Superhost
A spacious room is captured featuring a large bed dressed in white linens, complemented by decorative pillows. A chair is positioned nearby, next to a small table with a lamp. Natural light filters in through small windows, illuminating the warm color scheme and rustic wooden beams.
Private room in Yucay
New place to stay

Double room with private balcony. De Alba.

Superhost
A vibrant building is set among lush greenery, featuring a mural with warm colors on its exterior. A large table is positioned in the foreground, with surrounding trees and flowering plants adding to the natural ambiance. The backdrop reveals towering mountains beneath a partly cloudy sky.
Private room in Ollantaytambo

Full Moon Eco Lodge: Rumi 3

Superhost
A colorful building is situated in a lush garden, featuring vibrant artistic murals. Surrounding greenery includes blooming flowering plants and a picnic table set on the grass, with mountains providing a scenic backdrop under a blue sky.
Private room in Ollantaytambo

Full Moon Eco Lodge: Maiu 3

Superhost
A bright room features two individual beds with soft white linens, positioned beside wooden bedside tables. A cozy armchair is present, and natural light enters through a nearby window, enhancing the room's airy feel. Two wooden doors lead to additional private areas of the villa.
Private room in Yucay
New place to stay

Cozy Double room with separate beds. De Alba

Superhost
A spacious room showcases a wooden floor and large windows with natural light. A dining area with two decorated chairs and a low table is situated beside a staircase. The room's design includes warm tones, enhancing the overall inviting ambiance.
Guesthouse in Sacred Valley
4.5 out of 5 average rating, 4 reviews

Light Wood - Cabin 2

Superhost
An open and airy room features two spacious beds with soft linens in light tones. Natural light filters through large windows overlooking the garden. A wooden ceiling with exposed beams adds character. A small dining table and chairs are present, enhancing the cozy ambiance.
Private room in Yucay
New place to stay

Double room in the Sacred Valley. De Alba

Superhost
A colorful two-story building is highlighted with vibrant murals on its exterior. The surrounding garden features lush greenery and orange flowering plants. A picnic table and stool are visible on the lawn, providing a space for relaxation amidst nature.
Private room in Ollantaytambo
5 out of 5 average rating, 5 reviews

Full Moon Eco Lodge: Maiu 2

Superhost
An open space featuring wooden flooring and natural light from skylights. A cozy seating area with two patterned chairs complements a wooden table set with dishes. A staircase leads to an upper level, while a small kitchen area is visible in the background.
Guesthouse in Sacred Valley
5 out of 5 average rating, 5 reviews

Light wood - Cabin 3

Destinations to explore