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Vacation rentals in Isla Anzuelo

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Top-rated vacation rentals in Isla Anzuelo

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Top guest favorite
Boat in San Blas Islands
5 out of 5 average rating, 8 reviews

Private Catamaran live on board

Welcome aboard catamaran Yoyo, your floating home in the San Blas Islands. Your stay includes breakfast and snacks, with an optional meals and drinks package for USD 80 per person per day. For stays of 5 or more days, meals and drinks are included. Spend your days swimming, snorkeling, fishing, exploring hidden beaches, or relaxing on deck, and your nights unwinding under the stars. Experience the perfect blend of adventure, freedom, and laid-back island living with all the comfort you need.

Guest favorite
A stone pathway leads through lush tropical foliage toward a welcoming entrance. Tall trees and vibrant greenery frame the path, creating a serene approach to the property, which is partially visible in the background, surrounded by nature's tranquility.
Home in Panama City
4.98 out of 5 average rating, 80 reviews

Mountain Retreat

Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Villa in Panamá
5 out of 5 average rating, 3 reviews

Casa Condal - Your Private Nature Eco-Retreat

Disconnect from the city and reconnect with nature in this beautiful modern villa inside Chagres National Park. ✔ High-speed WiFi 65" Smart TV and Sound Bar ✔ Self check-in ✔ Private parking (2 cars) ✔ Fully equipped kitchen ✔ 220mts private trail ✔ Deck-Mirador with FirePit and panoramic view of the mountains and valley ✔ King bed + Full size sofa bed ✔ Wheelchair accessible 40 min from Tocumen Airport. Ideal for Birdwatchers, or a romantic getaway away from the city hectic rhythm.

Superhost
An aerial view captures the lush greenery of Narasgandub Island, surrounded by vibrant turquoise waters. The shoreline features a sandy beach bordered by palm trees, creating a tranquil atmosphere. The clear ocean extends into the horizon, highlighting the island's secluded paradise appeal.
Hut in San Blas
4.78 out of 5 average rating, 142 reviews

Bliss in the San Blas Islands

Discover Panama's best-kept secret in San Blas Islands, a set of 365 Caribbean Islands for 365 days of sun. All the Islands are owned by natives, "The Gunas," who will be very keen to welcome you and share their culture. Enjoy our crystal clear water, beautiful sunshine, and white sand, and wake up in the morning to hear the waves of the Ocean and see spectacular scenery from your room. A well-hidden Paradise awaits you in this unforgettable trip that will give you memories for a lifetime.

Guest favorite
A private hot tub sits at the edge of a tranquil lake, surrounded by lush greenery. The serene water reflects the clear blue sky, while the distant hills provide a peaceful backdrop. The tub's blue tiles contrast with the natural landscape.
Cabin in Panama City
4.91 out of 5 average rating, 65 reviews

#1 Cabin on the Lake Cerro Azul

Escape to the tranquil beauty of Cerro Azul, Panama and stay in our cozy lakeside cabin. With breathtaking views of the surrounding mountains and direct access to the lake, this is the perfect retreat for nature lovers. Enjoy fishing, kayaking, or simply relax on the private dock and soak in the serenity of the surroundings. Our fully equipped cabin has everything you need for a comfortable stay, including a full kitchen, comfortable bedroom, and a spacious balcony with panoramic views.

Guest favorite
Cabin in Panamá
4.93 out of 5 average rating, 87 reviews

The Crystal House: Luxury Modern Wood Cabin

Crea recuerdos inolvidables en este alojamiento único e ideal para familias. Quédate en una cabaña en medio del Parque Nacional Chagres a 50 minutos de la ciudad. Podrás estar en contacto con la naturaleza contando con todas las comodidades de un alojamiento de lujo. Con una de las mejores vistas a la ciudad puedes disfrutar de una buena barbacoa, una siesta en la hamaca o una reunión alrededor de la chimenea. Relájate y conéctate con el lindo verde de Panamá. Te esperamos!

Top guest favorite
Boat in Guna Yala Comarca
5 out of 5 average rating, 5 reviews

Private Caribbean Boat Retreat, San Blas Islands

Step aboard your own private floating villa in San Blas — no crowds, no shared spaces, just your group and one of the most untouched corners of the Caribbean. This is not a tour. It’s a fully private experience with a dedicated crew, optional chef service, and a completely customizable itinerary designed around you. Wake up surrounded by turquoise waters, explore deserted islands, snorkel vibrant reefs, or simply relax on deck with nothing but the ocean around you.

Superhost
Dome in Panamá
4.86 out of 5 average rating, 7 reviews

Skyline Dome |Falls View |Exclusive Retreat

Inspirado en el significado de Ibe, que simboliza equilibrio y conexión con la naturaleza, el Domo Ibe es un refugio pensado para el descanso y la desconexión. Combina diseño y confort con una cama queen y una cama full, aire acondicionado, baño privado con agua caliente, terraza y wifi de fibra óptica. La cocina está totalmente equipada. Rodeado de vegetación y aire puro, ofrece privacidad, calma y una experiencia auténtica en Cerro Azul.

Top guest favorite
Cottage in Panama City
4.97 out of 5 average rating, 35 reviews

Cerro Azul Mountain Retreat a magical home.

Enjoy every corner and luxury in this spacious house with 6 rooms with airs and 6 bathrooms. The perfect terrace to relax outdoors, while the ideal dining room to share special moments with your loved ones. The greenhouse is an oasis of fresh ingredients, ready to inspire delights. We have a new deck and jacuzzi ready to enjoy allowing you to connect with nature and beautiful sunsets. It has a game room, soccer pool table and a/ac

Superhost
Cottage in Panamá
4.82 out of 5 average rating, 96 reviews

Altos de Cerro Azul | AC, Full Kitchen, 2 Rooms

Some escapes stay with you. This is one of them. Located in the highlands of Altos de Cerro Azul, this modern mountain home is perfect for disconnecting without giving up comfort. Wake up to panoramic views, breathe cooler air, and enjoy true peace. Ideal for couples, small families, or remote workers seeking a calm retreat in nature. Traveling as a couple? Ask us about a special rate. No pets allowed.

Superhost
Hut in Mamartupo
4.77 out of 5 average rating, 90 reviews

Ancestral Serenity: Life in an Indigenous Cabin

Welcome to the Guna Yala archipelago, a truly captivating place. The 365 islands that make it up are a haven of biodiversity and rich indigenous culture. If you love nature, diving, or just relaxing to the sound of the waves, Guna Yala is an ideal destination. You can also explore the traditional cabins and taste the local cuisine, which is a reflection of the rich cultural heritage of the region.

Top guest favorite
Home in Panama City
5 out of 5 average rating, 23 reviews

Casa del Lago 2025

New lakefront house in Cerro Azul, decorated by a D&G architect with furniture brought from Bali. It has 3 bedrooms, 3 bathrooms and 4 double beds, equipped kitchen, BBQ, air conditioning and hot water. Cook a delicious BBQ with your friends in front of the lake and enjoy the sunsets from an unparalleled view with direct access and kayak included.

Popular amenities for Isla Anzuelo vacation rentals

  1. Airbnb
  2. Panama
  3. Isla Anzuelo