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Vacation rentals in Gulf of Guna Yala

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Gulf of Guna Yala

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Tiny home in Islas Maqui
5.0 out of 5 average rating, 10 reviews

Overwater Paradise Cabin| AnsuBirya | San Blas |

🌴 Stay in a traditional waterfront hut in the heart of the paradise-like San Blas archipelago. Surrounded by a turquoise lagoon, white beaches, and palm trees, it offers a unique getaway away from the crowds and mass tourism. Spend your days snorkeling, swimming, and exploring uninhabited islands with our kayak, which is provided with the cottage, and spend your evenings admiring the spectacular Caribbean sunsets. Indulge in seafood from our top chef, Ibin. The offer includes 3 meals a day in the restaurant.

Guest favorite
The modern cabin features a striking architectural design with large floor-to-ceiling windows, allowing for ample natural light and impressive views of the surrounding greenery. The entrance is framed by landscaped gardens and tall trees, providing a serene and inviting atmosphere.
Cabin in Panama City
4.98 out of 5 average rating, 42 reviews

Hyde Hills Luxury Mountain cabin with amazing view

Escape to luxury at our stunning cabin in the tranquil hills of Altos de Cerro Azul. Nestled in a lush jungle setting this spacious cabin offers breathtaking views of the surrounding nature. With highend finishes and comfortable furnishings, the cabin is the perfect place to relax and unwind. Enjoy a glass while looking the sunset or simply lounge on the terrace and take in the serene surroundings. Whether you're looking for a romantic getaway or a family vacation our cabin has something for you

Top guest favorite
Place to stay in Panama City
5.0 out of 5 average rating, 20 reviews

Casa Condal - Your Luxury Retreat in Cerro Azul

Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Guest favorite
A modern living space features large floor-to-ceiling windows revealing lush green views of the surrounding forest. A light wood floor enhances the open layout, which includes a sleek dining area and comfortable seating. A potted plant adds a natural touch to the interior.
Home in Los Altos De Cerro Azul, Panama
4.95 out of 5 average rating, 22 reviews

Welcome to Zola Sierra! Your Escape Into Nature.

Welcome to Zola Sierra. Your Private Escape Into the Heart of Nature. Step into the serenity of Zola Sierra, a one-of-a-kind 3-bedroom, 3-bath sanctuary nestled deep within the protected highlands of Cerro Azul, Panama. Designed for dreamers, seekers, and soul-restorers, this home is more than a stay — it’s a nature-immersive experience that effortlessly blends modern luxury with untamed wilderness. Come for the views. Stay for the stillness. Fall in love with the wild magic of Zola Sierra!

Top guest favorite
Boat in San Blas Islands
5.0 out of 5 average rating, 8 reviews

Private Catamaran live on board

Welcome aboard catamaran Yoyo, your floating home in the San Blas Islands. Your stay includes breakfast and snacks, with an optional meals and drinks package for USD 80 per person per day. For stays of 5 or more days, meals and drinks are included. Spend your days swimming, snorkeling, fishing, exploring hidden beaches, or relaxing on deck, and your nights unwinding under the stars. Experience the perfect blend of adventure, freedom, and laid-back island living with all the comfort you need.

Superhost
An aerial view showcases a rustic cottage surrounded by lush palm trees, located near a sandy beach. The gentle waves of the ocean are visible, along with several red-roofed structures nestled within the greenery, creating a serene coastal atmosphere.
Cottage in Palenque
4.87 out of 5 average rating, 95 reviews

Beachfront House in Caribbean sandy beach

Enjoy this rustic and cozy cottage with its almost private beach surrounded by beautiful palm trees along the whole area. With 2 oceanview bedrooms, 2 full bathrooms and a third bedroom in a mezzanine. Has a patio with a built in uruguayan parrilla, ideal for BBQs. Step in beautiful white sand and bath in crystal clear water. Coconut breakfasts watching the sunrise become a routine in this paradise. - This is a rural setting. Not a 5 star hotel. Insects and small animals can be around.

Superhost
Home in Playa Chiquita
5.0 out of 5 average rating, 7 reviews

Caribbean Jungle Beach House

Secluded loft beach house on 7 hectares of jungle with pristine beach. Enjoy the peaceful tranquility of coconut palm tree covered golden sand beach with shallow warm water great for swimming and body surfing. Lounge chairs, barbecue, kayaks, snorkel masks, boogie boards, hammocks and a fire pit for beach bonfires under the starry night sky all available. Great for families, couples or groups of friends. Delicious Panamanian food made to order on site. Tent camping (glamping) also available.

Guest favorite
Boat in San Blas Islands
5.0 out of 5 average rating, 33 reviews

Eco Sailing in Paradise Private - All inclusive

Enjoy a fully private sailing experience The boat is shared only with the crew. A perfect getaway for couples or families with kids. Where you don’t have to worry about anything, just enjoy. We host a maximum of 4 guests on board, ensuring space, comfort, and a relaxed atmosphere at all times. We are committed to sustainable living at sea and use eco-friendly cleaning products, biodegradable toiletries, and ocean-safe sunscreen to help protect the reefs and marine life of San Blas.

Guest favorite
Boat in Panamá
5.0 out of 5 average rating, 5 reviews

Boat in San Blas

PRICE FOR 2 PEOPLE. Sailing adventure in San Blas with biologists Nico and Belu! Spend unforgettable days enjoying nature. The sailboat includes: 2 double cabins, living room, kitchen and outdoor cockpit. The rate is full board (breakfast, lunch, dinner), plus free use of snorkeling, stand-up paddle and kayak equipment. The price does NOT cover transportation to San Blas or the taxes for access to the Guna Yala Region and the islands. From 12/20 to 01/05, prices increase by 20%

Superhost
Hut in Cayos Chichime
4.83 out of 5 average rating, 6 reviews

Barefoot Cabin on Chichime Chico

Beautiful island of Chichime Chico. Enjoy rustic beachfront charm with wooden‑floor cabins, shared bathrooms, and fresh daily meals included. Relax into laid‑back island life with turquoise waters, coral reefs, and great snorkeling just steps away. Hosted by the local Guna community on a simple and wild island. Tours are not included. They can be arranged on‑site depending on availability, with prices starting from US$15 per person, depending on the destination.

Guest favorite
Cabin in Panama City
4.93 out of 5 average rating, 90 reviews

The Crystal House: Luxury Modern Wood Cabin

Create unforgettable memories at this unique and family-friendly place. Stay in a cabin in the middle of Chagres National Park, 50 minutes from the city. You can be in contact with nature while having all the comforts of a luxury accommodation. With one of the best views of the city, you can enjoy a good barbecue, a nap in the hammock, or a meeting around the fireplace. Relax and connect with the beautiful green of Panama. We'll be waiting for you!

Guest favorite
Home in Panama City
5.0 out of 5 average rating, 16 reviews

3BR Mountain Retreat | Starlink WiFi | Cerro Azul

Escape to the cool mountain weather of Cerro Azul and enjoy a modern home surrounded by nature. Perfect for families, groups of friends, and remote work, with high-speed Starlink internet for seamless video calls and streaming. Relax on the spacious balcony, enjoy the BBQ gazebo, and unwind from city life while surrounded by fresh air, peaceful surroundings, and natural views. Have questions? Send us a message today!

Popular amenities for Gulf of Guna Yala vacation rentals

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