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Vacation rentals in Gulf of Guna Yala

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Top-rated vacation rentals in Gulf of Guna Yala

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Tiny home in Islas Maqui
5.0 out of 5 average rating, 14 reviews

Overwater Paradise Cabin| AnsuBirya | San Blas |

🌴 Stay in a traditional waterfront hut in the heart of the paradise-like San Blas archipelago. Surrounded by a turquoise lagoon, white beaches, and palm trees, it offers a unique getaway away from the crowds and mass tourism. Spend your days snorkeling, swimming, and exploring uninhabited islands with our kayak, which is provided with the cottage, and spend your evenings admiring the spectacular Caribbean sunsets. Indulge in seafood from our top chef, Ibin. The offer includes 3 meals a day in the restaurant.

Top guest favorite
Place to stay in Panama City
5.0 out of 5 average rating, 26 reviews

Casa Condal - Your Luxury Retreat in Cerro Azul

Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Guest favorite
A modern living space features large floor-to-ceiling windows revealing lush green views of the surrounding forest. A light wood floor enhances the open layout, which includes a sleek dining area and comfortable seating. A potted plant adds a natural touch to the interior.
Home in Los Altos De Cerro Azul, Panama
4.96 out of 5 average rating, 24 reviews

Welcome to Zola Sierra! Your Escape Into Nature.

Welcome to Zola Sierra. Your Private Escape Into the Heart of Nature. Step into the serenity of Zola Sierra, a one-of-a-kind 3-bedroom, 3-bath sanctuary nestled deep within the protected highlands of Cerro Azul, Panama. Designed for dreamers, seekers, and soul-restorers, this home is more than a stay — it’s a nature-immersive experience that effortlessly blends modern luxury with untamed wilderness. Come for the views. Stay for the stillness. Fall in love with the wild magic of Zola Sierra!

Guest favorite
Boat in San Blas Islands
5.0 out of 5 average rating, 8 reviews

Private Catamaran live on board

Welcome aboard catamaran Yoyo, your floating home in the San Blas Islands. Your stay includes breakfast and snacks, with an optional meals and drinks package for USD 80 per person per day. For stays of 5 or more days, meals and drinks are included. Spend your days swimming, snorkeling, fishing, exploring hidden beaches, or relaxing on deck, and your nights unwinding under the stars. Experience the perfect blend of adventure, freedom, and laid-back island living with all the comfort you need.

Superhost
An aerial view showcases a rustic cottage surrounded by lush palm trees, located near a sandy beach. The gentle waves of the ocean are visible, along with several red-roofed structures nestled within the greenery, creating a serene coastal atmosphere.
Cottage in Palenque
4.87 out of 5 average rating, 95 reviews

Beachfront House in Caribbean sandy beach

Enjoy this rustic and cozy cottage with its almost private beach surrounded by beautiful palm trees along the whole area. With 2 oceanview bedrooms, 2 full bathrooms and a third bedroom in a mezzanine. Has a patio with a built in uruguayan parrilla, ideal for BBQs. Step in beautiful white sand and bath in crystal clear water. Coconut breakfasts watching the sunrise become a routine in this paradise. - This is a rural setting. Not a 5 star hotel. Insects and small animals can be around.

Superhost
Cabin in Cayos Limon
5.0 out of 5 average rating, 3 reviews

Miryadub: Peaceful Escape • Full Board & Tour

🌴 Miryadub is a quiet, non-touristic island in Guna Yala for overnight guests only, offering a peaceful and authentic San Blas experience away from the crowds. The island is small and made for slowing down, disconnecting and enjoying nature. While it does not have a large beach, guests usually spend the day exploring nearby islands, snorkeling spots and crystal-clear natural pools with tours organized by the local Guna family. Perfect for travelers seeking a calm and authentic island stay.

Top guest favorite
Cabin in Panama City
4.9 out of 5 average rating, 21 reviews

Casita Pino Azul, Natural Escape + Jacuzzi + Relax

Enjoy a cozy experience among mountains, birds and fresh air in Cerro Azul. Relax with the whole family in this accommodation where tranquility is breathed. Surrounded by nature and tranquility. Ideal for couples or families looking to disconnect without leaving the city. It has comfortable beds, equipped kitchens, a Jacuzzi, WiFi and a private terrace. Perfect for relaxing, sharing with family, or a weekend getaway. Located in a safe area, with easy access and cool climate.

Top guest favorite
A sailing yacht rests in clear blue waters near a sandy beach bordered by palm trees. Small boats can be seen cruising nearby, and a colorful structure is visible on the shore, surrounded by lush greenery and the expansive ocean.
Boat in San Blas Islands
5.0 out of 5 average rating, 24 reviews

73ft Family Sailing Yacht, Unique & Very Spacious

Spend your family vacation on "Sailing Renaissance", a unique 73feet (22m) long, the largest sailing yacht available, with Professional Captain and Chef included. We have two kids onboard (9 & 11) All meals are included. Max 4 guests If you are looking for comfort, privacy, amazing experience, excellent food and great services, this is the right place. This is a Private Yacht, there will be only you and the crew. We have all the watertoys you need and High Speed Internet.

Guest favorite
Cabin in Panama City
4.93 out of 5 average rating, 92 reviews

The Crystal House: Luxury Modern Wood Cabin

Create unforgettable memories at this unique and family-friendly place. Stay in a cabin in the middle of Chagres National Park, 50 minutes from the city. You can be in contact with nature while having all the comforts of a luxury accommodation. With one of the best views of the city, you can enjoy a good barbecue, a nap in the hammock, or a meeting around the fireplace. Relax and connect with the beautiful green of Panama. We'll be waiting for you!

Guest favorite
Cabin in Cayos Chichime
4.74 out of 5 average rating, 35 reviews

An-Dutu Boutique Cabins

Welcome to An-Dutu Boutique Cabin, an exclusive experience in the heart of San Blas. Our cabin is the only one in the entire area with air conditioning, designed for those who wish to experience the natural beauty of the archipelago without compromising on comfort. Designed to accommodate up to 4 people, An-Dutu combines the rustic charm of the islands with carefully selected details for a comfortable, private, and memorable stay."

Top guest favorite
Cottage in Panama City
4.95 out of 5 average rating, 40 reviews

Cerro Azul Mountain Retreat un hogar mágico.

Enjoy every corner and luxury in this spacious house with 6 rooms with airs and 6 bathrooms. The perfect terrace to relax outdoors, while the ideal dining room to share special moments with your loved ones. The greenhouse is an oasis of fresh ingredients, ready to inspire delights. We have a new deck and jacuzzi ready to enjoy allowing you to connect with nature and beautiful sunsets. It has a game room, soccer pool table and a/ac

Guest favorite
An open-concept living area is showcased, featuring a modern kitchen island with a sleek countertop. A dining table accommodates several chairs, while a cozy seating arrangement near large windows reveals views of the natural surroundings. A gas grill is visible on the balcony.
Cottage in Panama City
4.83 out of 5 average rating, 115 reviews

Altos de Cerro Azul | AC, Full Kitchen, 2 Rooms

Some escapes stay with you. This is one of them. Located in the highlands of Altos de Cerro Azul, this modern mountain home is perfect for disconnecting without giving up comfort. Wake up to panoramic views, breathe cooler air, and enjoy true peace. Ideal for couples, small families, or remote workers seeking a calm retreat in nature. Traveling as a couple? Ask us about a special rate. No pets allowed.

Popular amenities for Gulf of Guna Yala vacation rentals