
Hotels in Central Business District
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Top-rated hotels in Central Business District
Guests agree: these hotels are highly rated for location, cleanliness, and more.

Two Queen Room - 2 beds
This Deluxe Room offers a nature view with 2 queen beds. Features include TV with pay-per-view, coffee maker, hair dryer, alarm clock radio and private voice mail.<p><b>Ho*Description</b></p>At Caesars Southern Indiana, you can look forward to a casino, a nightclub, and concerts and live shows. Hit the jackpot at this ho*with amenities such as a casino VIP room, 1800 slot machines, and 100 casino gaming tables. Treat yourself to a deep-tissue massage, a body wrap, or a manicure/pedicure at the o

Near River Ridge Commerce Center + Dining & Gym
Skip the chain feel—this stay is all about ease, location, and unexpected perks. Just across the river from downtown Louisville, this pet-friendly hotel puts you close to the Big Four Bridge, Whiskey Row, and bourbon-fueled adventures. After a day exploring, refuel at the on-site bar, break a sweat in the 24/7 gym with Peloton bikes, or chill in your spacious room. Free parking, friendly staff, and thoughtful touches? It’s the Airbnb-friendly hotel experience you didn’t know you needed.

Stay at the Mod Pod!
The Mod Pod is a tiny, funky, atomic space located in the historic district of downtown New Albany Indiana- located next to our sci fi diner Lady Tron’s. The Pod sleeps up to 4 guests with a queen loft bed, full sized pull out, twin sized roll away. Don’t let our vintage vibe fool you- we have all of the creatures comforts! High speed internet 85 inch google tv Ample device charging Kitchenette with fridge/freezer, microwave and coffee maker Walk in shower Bidet Hair dryer and iron

Discover Vibrant Culture In Downtown Louisville
Located in the heart of Downtown Louisville, Fairfield Inn and Suites Louisville Downtown puts you within walking distance of top attractions. Just a short drive away, you can experience the iconic Churchill Downs, home of the Kentucky Derby. Kickstart your day with our complimentary breakfast buffet, offering a selection of classic American favorites like bacon and eggs. After a busy day, unwind in our indoor pool or stay active in our 24-hour fitness center.

Double Queen Room Second Floor
Modern Art Deco Charm in the Highlands Stay in a piece of Louisville history! Located in a restored 1920s police station/ballet school, our Double Queen room blends vintage style with modern comfort. Sleeps 4: Two plush Queen beds. Amenities: Kitchenette, LATHER toiletries, and local Heine Bros coffee. Local Vibes: We live in the neighborhood and love hosting! Walk to "Restaurant Row" or Cherokee Park. Experience the Highlands like a local at The Bellwether.

Enjoy Southern Hospitality | Free Breakfast
Enjoy Southern hospitality and a great location when you book SpringHill Suites Louisville Downtown. Our all-suite hotel just off I-65 puts you steps from the iconic Whiskey Row. A few blocks away you can tour the city’s famous bourbon distilleries, shop in the NuLu district, or explore waterfront attractions. In the morning, stretch out your muscles in the fitness center or indoor pool before heading to our free breakfast buffet.

Across University of Louisville + Free Breakfast
Designed with extended-stay travelers in mind, Residence Inn Louisville East offers upscale, all-suite accommodations with the comfort and privacy of apartment-style living. Start your morning with a complimentary hot breakfast buffet, then energize with a workout at our nearby fitness center. Located directly across from the University of Louisville Shelby campus, our hotel is a convenient choice for campus visitors.

2 Queen | Wyndham Louisville KY | Family Base
Great for shared trips, this East Louisville stay keeps you close to the best of the city without the hassle. Fuel up with free breakfast, then head to Churchill Downs, the Louisville Science Center, or the Slugger Museum downtown. After exploring, reset at the fitness center or relax in the courtyard with a drink from the lobby bar—an easy home base for museums, campus visits, and game days.

Exec Suite 2 Queens | Galt House | Ohio Rv Front
With the Ohio River as your backdrop, The Galt House delivers an immersive Louisville experience—close to museums, downtown shops, and spirited bourbon culture. The West Tower Suite offers two queen beds, a living space, and dramatic water views—ideal for families or friends sharing an unforgettable stay. Enjoy sweeping skyline reflections with your morning coffee in hand.

Hotel Hilo - Room 101
Hotel Hilo is a bold, boutique stay on the grounds of Louisville’s iconic ATOMIC Soundclub. Each of our 8 king-bed rooms blends retro-modern style with luxe touches and shared balcony or patio access. Designed for both hi-energy nights and lo-key recoveries, Hilo is your launchpad for vibing hard, resting well, and experiencing the best of the Highlands—day or night.

Hawthorn Louisville | King Exec Suite | Near I-264
Stay near top Louisville attractions and enjoy Southern hospitality just off I-264, minutes from Churchill Downs and downtown. This executive suite boasts a spacious layout, featuring a king bed, a living area, and a well-equipped kitchenette. It's ideal for guests looking for extra comfort during extended stays or business trips.

Fully Equipped Room Near Center Mall - 5 miles
Apartment-style suites for longer stays with free WiFi, parking, and a pet-friendly welcome. Located near Louisville Mega Cavern and Churchill Downs, our accessible rooms and attentive service create a comfortable, home-like stay. Enjoy a practical location close to top attractions—your easy gateway to exploring Louisville.
Popular amenities for Central Business District hotels
Family-friendly hotels

Galt House | Deluxe King | Near Museum Row & Bourb

Experience Convenient Stays Near Mall St. Matthews

2BR Waterview Suite | Galt House | Onsite Dining

Hawthorne Louisville | 1BR Suite | Heated Pool

Galt House | Deluxe 2 Q West Tower | Near Museums

Executive 1BR King Suite | Galt House East Tower

1BR Suite 2 Queens | Galt House | Enjoy Waterviews

Deluxe 2 Queen | Galt House | Waterfront Hotel
Hotels with a pool

Experience True Southern Comfort | Free Breakfast

Pleasant Stay near Skyview Park | Free Breakfast

King Room - 1 bed

Wingate Louisville | 1BR Suite | Close to Airport

Wingate Louisville | Deluxe Queen | Comp Breakfast

Welcoming Room w/ Free Breakfast & Indoor Pool

King Room by I-64 | Indoor Pool & Free Parking

Galt House | Executive 1BR King Suite | Lap Pool
Hotels with a patio

Sleep10 5Beds 4BR 2BA A12 War Admiral 1400

Sleep12 6Beds 4BR 2BA A12 Triple Crown Assault 110

Stay at the Mod Pod!

Sleep10 5Beds 4BR 2BA A12 Secretariat 2400

Sleep12 6Beds 4BR 2BA A12 American Pharoah 2300
Quick stats about hotels in Central Business District

Total vacation rentals
Explore 30 vacation rentals in Central Business District

Nightly prices starting at
Central Business District vacation rentals start at ﺩ.ﺇ 661 per night before taxes and fees

Verified guest reviews
Over 250 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 30 rentals that welcome pets

Vacation rentals with a pool
30 properties feature pools

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wi-Fi availability
30 of Central Business District vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Central Business District rentals

4.8 Average rating
Central Business District stays are highly rated by guests—averaging 4.8 out of 5!

Nearby attractions
Central Business District's top spots, include Fourth Street Live!, Louisville Slugger Museum & Factory, and Louisville Slugger Field
Destinations to explore
- Rentals with an EV charger Downtown
- Apartment rentals Downtown
- Pet-friendly rentals Downtown
- Fitness-friendly rentals Downtown
- Condo rentals Downtown
- Rentals with a patio Downtown
- Rentals with a hot tub Downtown
- Rentals with a washer and dryer Downtown
- Rentals with pools Downtown
- Rentals with outdoor seating Downtown
- Loft rentals Downtown
- Rentals with breakfast Downtown
- Rentals with a fire pit Downtown
- Family-friendly rentals Downtown
- Hotel rooms Louisville
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- Buffalo Trace Distillery
- Kentucky Exposition Center
- Kentucky Derby Museum
- Kentucky Kingdom & Hurricane Bay
- Churchill Downs
- Louisville Slugger Field
- Louisville Slugger Museum & Factory
- Muhammad Ali Center
- Angel's Envy Distillery
- Waterfront Park
- Falls of the Ohio State Park
- Jefferson Memorial Forest
- Big Four Bridge
- University of Louisville
- Kentucky International Convention Center
- Kentucky Science Center
- Bernheim Arboretum and Research Forest
- Frazier History Museum
- James B Beam Distilling
- Cherokee Park
- Marengo Cave National Landmark
- Against The Grain Brewery & Smokehouse
- Evan Williams Bourbon Experience
- Bardstown Bourbon Company





