Vacation rentals in Central Business District

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Top-rated vacation rentals in Central Business District

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A spacious living area features a large, comfortable sectional couch adorned with plush pillows. A low coffee table is positioned at the center, with large windows allowing abundant natural light. The space is accented by a decorative rug and the industrial-style ceiling adds character.
Condo in Central Business District
4.95 out of 5 average rating, 259 reviews

★ Victorian Louisville ★ 1000 sqft Glassworks Loft

Fresh, modern and sleek 950 SqFt loft style unit. Constructed inside the historic glassworks building, this condo is one of the most unique in the city. You will be amazed by the style, but also the amenities nearby. With a 2 minute walk to Museum row, and a 7 minute walk whiskey row, the convention center, the YUM! center and the center for the arts - everything is nearby. With Wifi, Netflix, and Hulu provided you have everything you need. The perfect spot for relaxing or going out on the town

Top guest favorite
Condo in Central Business District
4.99 out of 5 average rating, 157 reviews

Glassworks Loft at Louisville Skyline

This unique and modern 850 square foot downtown loft is situated in the historic Glassworks building; boasting 12-foot ceilings and a wall of windows overlooking Louisville’s CBD and the Ohio river bridges / fireworks of Thunder. Enjoy all of the comforts of home with new scenery or venture out and relish our great city. Ideal for couples but can sleep 4 comfortably. Great for business or pleasure with close proximity to the KICC, Slugger Factory, Yum Center and 7 distilleries within 4 blocks.

Top guest favorite
Apartment in East Market District
4.91 out of 5 average rating, 105 reviews

Newly renovated modern condo in NuLu District!

Discover “Pour Decisions,” a chic 3-story 2BR/2BA condo in Louisville’s vibrant NuLu district. Enjoy a cozy living room with Smart TV, a fully equipped kitchen, and two private patios, including a rooftop deck. The main suite features a plush king bed and ensuite bath. Just steps from NuLu, East Market District, Whiskey Row, Downtown, and top dining, this stylish retreat offers high-speed Wi-Fi, self-check-in, and modern comforts, your perfect Louisville getaway. Book your convenient stay now!

Top guest favorite
Loft in Central Business District
4.97 out of 5 average rating, 950 reviews

Bourbon City Loft - Free downtown parking!

If this loft is booked, please check out my other listings.. www.airbnb.com/h/derby-city-loft www.airbnb.com/h/river-city-loft www.airbnb.com/h/falls-city-loft Spacious 950 sq. ft. loft located in the heart of downtown Louisville. Walking distance to shops, restaurants, bars and 1 block from 4th Street Live! Located 4 blocks from the YUM! Center, 2 blocks from the Kentucky International Convention Center, and less than 10 minutes from Churchill Downs! Free parking in a secured parking garage!

Guest favorite
An open living area features exposed brick walls and hardwood flooring, enhanced by natural light from large windows. A spacious leather couch is complemented by a wooden coffee table and two ceiling fans. The kitchen showcases a granite island and modern appliances.
Condo in Central Business District
4.9 out of 5 average rating, 280 reviews

Downtown Condo | Private 1 CAR Garage & Balcony

Beautiful Downtown Loft Condo with private balcony overlooking 4th Street. Walking distance to fantastic eateries, bars, concerts, ball games, and much more. Steps to the Palace Theater and 4th Street Live and next door to the Seelbach Hotel. Private 1 CAR, connected to the building for easy downtown parking. Building has secure entry and an elevator. The building is an old clothing department store, BYCKS. This 4th floor unit boasts exposed ceilings, brick walls, and hardwood flooring.

Top guest favorite
The kitchen features modern appliances, including a large stainless steel refrigerator and an oven. A wooden dining table, surrounded by eight black woven chairs, provides a space for gatherings. Bright orange walls complement the light wood flooring, creating a welcoming atmosphere.
Apartment in East Market District
4.98 out of 5 average rating, 300 reviews

Urban Bourbon Stay - Nulu 2 BR * 2 Full Bath

Beautifully renovated historic 2 bedroom 2 full bath apartment in Louisville's hip Nulu neighborhood. Huge 1,500 sq ft space to relax in after enjoying all the shops and restaurants in the Nulu area. This apartment is just a few blocks east of downtown. It's a great area to kickoff your Louisville adventures. This apartment is above a boutique wine and bourbon shop and within walking distance of several distilleries, so you don't have far to go to sample some of Kentucky's legendary bourbon.

Guest favorite
Apartment in Central Business District
4.91 out of 5 average rating, 312 reviews

4th Street Suites - Opulent King Bed Suite

Live the best of Louisville in this sleek 1‑bed, 1‑bath downtown retreat! Perfect for couples, families, or friends, it features a cozy king bed, pullout couch, a fully stocked kitchen, and a bright living area. Wake up to city sights, stroll to restaurants and bars, then relax by the pool or hot tub, play a round in the golf simulator, or unwind with a game of pool in the clubhouse. This is your launchpad for adventure—or a quiet, stylish escape when it’s time to rest. Come make it yours!

Top guest favorite
A spacious living area is highlighted by large windows that provide ample natural light. A comfortable sectional sofa is positioned around a central coffee table, with decorative cushions adding color. A vibrant area rug anchors the seating area, complemented by greenery from potted plants.
Condo in Central Business District
4.98 out of 5 average rating, 186 reviews

The Derby City Loft, luxury, walk to museum row

Located in historic downtown Louisville the Derby City Loft is a show stopper! This PENTHOUSE luxury condo offers stunning views and high end living. The open floor plan boasts 3 queen beds, curtains can be pulled to make it a 2 bedroom. Plus the oversized sectional sofa may sleep 2 comfortably as well. Fully stocked kitchens and bathrooms with everything! This home was designed and styled with your comfort in mind, kick back, relax and enjoy high style living at the Derby City Loft.

Superhost
A spacious living area is highlighted by large windows allowing natural light to fill the room. Two comfortable sofas are arranged around a minimalist coffee table, while a foosball table adds a playful touch. A television is positioned on a simple media console against the wall.
Apartment in Central Business District
4.94 out of 5 average rating, 127 reviews

Historic Whiskey Row Lofts in Heart of Downtown

Book your stay at the historic Whiskey Row Lofts in the heart of Louisville's cultural, commercial, and entertainment district! Experience the unique architectural features of one of the city's flagship historic buildings, including 12' windows, exposed brick walls, and original molding. You'll be on top of Whiskey Row, the center of bourbon tourism, and just blocks from Museum Row and Louisville's major event centers, such as the KFC Yum! Center and the International Convention Center.

Guest favorite
Condo in Central Business District
4.93 out of 5 average rating, 221 reviews

Derby Depot Cozy 1BR Central Location Free Parking

The Theatre Building is a beautifully renovated Art Deco building listed on the Historical Register located next to the Palace Theater. You will enjoy easy access to all of downtown from our central location for fun or work. The unit has its own dedicated high speed (300MB) wi-fi connection, HDTV w/cable & streaming apps, as well as 1 FREE off-street, hotel garage parking space. There are numerous entertainment, shopping, dining and bourbon tasting options available within a short walk.

Top guest favorite
A spacious living area features a large sectional sofa and a coffee table, set on a textured area rug. A flat-screen television is positioned on an elegant TV stand, with large windows allowing natural light to illuminate the space.
Condo in East Market District
4.99 out of 5 average rating, 110 reviews

Walk to Bourbon Trail | NULU Gem | Gated Parking

Stay in the heart of NULU—this modern ground-floor condo puts you steps from Louisville’s best restaurants, bourbon stops, and local shops. Walk to favorites like Angel’s Envy and Rabbit Hole Distillery, enjoy all the NuLu dining, or head downtown in minutes for concerts, games, or events. The condo is comfortable, quiet, and thoughtfully set up—ideal for couples, solo travelers, or business stays, with gated parking, fast Wi-Fi, and everything needed for short or extended stays.

Guest favorite
A spacious rooftop patio is highlighted by stylish furniture, including a large sectional and coffee table. Potted plants add greenery, while a scenic river view stretches in the background beneath a clear blue sky filled with light clouds.
Condo in Central Business District
4.98 out of 5 average rating, 182 reviews

Charming Penthouse/Rooftop Patio/Downtown

Unwind and enjoy sweeping river views on the rooftop patio while staying in this private 5th floor Penthouse apartment. Intentionally designed and decorated. Features include: a full upscale kitchen, open concept living and dining area, cozy King bed, large plush bathroom, and laundry in the suite. Whether visiting for work or pleasure, this spacious urban suite is located on The Bourbon Trail and within walking distance to Louisville's most popular venues!

Popular amenities for Central Business District vacation rentals

Quick stats about vacation rentals in Central Business District

  • Total vacation rentals

    Explore 350 vacation rentals in Central Business District

  • Nightly prices starting at

    Central Business District vacation rentals start at ﺩ.ﺇ220 per night before taxes and fees

  • Verified guest reviews

    Over 20,620 verified reviews to help you choose

  • Family-friendly vacation rentals

    170 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 150 rentals that welcome pets

  • Vacation rentals with a pool

    50 properties feature pools

  • Rentals with dedicated workspaces

    250 properties have a dedicated workspace

  • Wi-Fi availability

    340 of Central Business District vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Central Business District rentals

  • 4.8 Average rating

    Central Business District stays are highly rated by guests—averaging 4.8 out of 5!

  • Nearby attractions

    Central Business District's top spots, include Fourth Street Live!, Louisville Slugger Museum & Factory, and Louisville Slugger Field

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  2. United States
  3. Kentucky
  4. Jefferson County
  5. Louisville
  6. Downtown