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House vacation rentals in Santo Domingo de Guzman

Find and book unique houses on Airbnb

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Popular amenities for Santo Domingo de Guzman house rentals

House rentals with a pool

Guest favorite
Home in Santo Domingo
5 out of 5 average rating, 13 reviews

Steel-Loft - Whole house with sea-view terrace

JustineRating, 5 stars3 months ago
We had a wonderful stay at this beautiful, modern, convenient house. Manuel was a truly great host - friendly, communicative, and prompt to respond to any issue. I really appreciated the detailed instructions on how to find the house and get inside. We loved the small plunge pool/ hot tub, as well as the roof terrace, and the location was great for walking to lots of restaurants and shops in the colonial zone. Thank you for a great stay in Santo Domingo!
Top guest favorite
Home in Santo Domingo
5 out of 5 average rating, 6 reviews

Casa Grullon, an Oasis in the Colonial Zone

AndyRating, 5 stars1 month ago
Great walkable location in Zona Colonial. Well outfitted with AC units and washer/dryer, as well as other comforts. Very well decorated, and the pool was a nice touch to have when the weather got warm. The host was extremely responsive and helpful during our stay. Would recommend to anyone looking to stay in Santo Domingo.
Superhost
Home in Santo Domingo Norte
4.75 out of 5 average rating, 20 reviews

PrivatePool - BBQ - Terrace - Excelent for Big Fam

AllenRating, 5 stars5 months ago
A very nice place especially the pool area which has plenty of furniture for entertaining. Clean house in a secure area.
Guest favorite
Home in Santo Domingo
5 out of 5 average rating, 8 reviews

Stunning villa in Zona Colonial

CydneyRating, 5 stars1 month ago
Jorge's place is
Superhost
Home in Herrera
5 out of 5 average rating, 3 reviews

House/Santo Domingo Oeste/ POOL

ElijahRating, 5 stars1 month ago
Best stay i ever had in dominican republic very gracious host very attentive, polite , great prices , beautiful peaceful home , very responsive , highly recommended close to supermarkets beautiful neighborhood will 100% stay there again
Superhost
Home in Santo Domingo
4.87 out of 5 average rating, 71 reviews

Casa Aló:Private house with jacuzzi in the Capital

HaidyRating, 5 stars1 week ago
I feel at home!!! Tony and Ramona are very good and nice. It's already my top 1 to enjoy with family and friends. 200% recommended!!!
Superhost
Home in Santo Domingo
4.78 out of 5 average rating, 9 reviews

AD featured slow life villa & scenic pool

IanRating, 5 stars5 months ago
This is a perfect location for a group. Each room is essentially an efficiency apartment with a small kitchen and bath. The history is evident and I love this part of the city. I recommend it highly. The pool however does not get much sun, but it’s charming and good for a dip!
Guest favorite
Home in Santo Domingo
4.89 out of 5 average rating, 27 reviews

Simply beautiful

AlbaRating, 5 stars1 week ago
I loved how easy it was to communicate with the host anytime I had a question about anything. The place is lovely, It’s exactly just for one person or a couple that wants to get away for a bit. Loved that I was able to cook and clean just how I do it back home and just enjoyed being there. I would say, it’s not as big as i usually like the apt to be like but it was still cozy and nice.

Weekly house rentals

Guest favorite
Home in Santo Domingo
4.8 out of 5 average rating, 20 reviews

Large family residence

MellisaRating, 5 stars2 weeks ago
2nd time staying and even better this time. central location and convenient. we will be back :)
Home in Santo Domingo
4.85 out of 5 average rating, 89 reviews

Colonial Treasure + Historic 2BR House+Terrace

OlgaRating, 5 stars4 months ago
I had an exceptional stay at this Airbnb! From the moment I arrived, everything was perfectly in order and immaculately clean. The attention to detail was truly impressive, and it exceeded all my expectations. The space was comfortable, well-equipped, and thoughtfully designed to make guests feel at home. The host was responsive and welcoming, making the entire experience smooth and enjoyable. I would highly recommend this property to anyone looking for a top-notch stay!
Guest favorite
Home in Santo Domingo Province
4.83 out of 5 average rating, 6 reviews

House in Santo Domingo

AnnelouRating, 5 stars15 months ago
Excellent host and secure location. The house is beautiful just as described. I will definitely come back
Home in Santo Domingo
4.83 out of 5 average rating, 60 reviews

Beautiful modern Colonial House with terrace

SilvestreRating, 5 stars1 month ago
Fanny's place was exactly what I was looking for. It was quiet, calm and spacious. The terrace upstairs and the courtyard were nice additions. There is a colmado (corner store) next door and the apartment is only a few blocks from the main tourist area. I highly recommend booking. I was fortunate enough to have met the host and I feel even more secure in my decision to stay here because she is extremely kind and helpful. I highly recommend booking.
Home in Santo Domingo
4.75 out of 5 average rating, 4 reviews

Lovely Relaxing home with parking

AlexisRating, 5 stars20 months ago
It's my second time in this place and I love the house, super comfortable. My favorite place to stay when I work and need a place.
Home in Santo Domingo
4.76 out of 5 average rating, 68 reviews

Zona Colonial Large Room, Private Bath & Entrance

JenniferRating, 5 stars3 months ago
What a lovely place to stay! Super safe and quiet. Solomon was really helpful as a host. Excellent value for money and a very peaceful location. If I come back to the DR I will definitely be staying again.
Home in Altos Arroyo Hondo II
4.9 out of 5 average rating, 41 reviews

Charming 2BDR Suite! - SPECIAL PROMOTION

CarlosRating, 5 stars4 months ago
Safe place, very attentive host.
Home in Santo Domingo
4.67 out of 5 average rating, 3 reviews

Spain Villa w/ Botanical & Pool

DavinaRating, 5 stars1 month ago
My husband and I enjoyed Oscar's lovely home very much. The home is spacious. The bed was very comfortable. The hot water was fantastic. The kitchen is well equiped and we were able to cook dinner there. The washer and dryer were very convenient. UberEats is available for restaurant and grocery delivery. Oscar's home and gardens are very peaceful and beautiful. There are so many birds in the garden and we really enjoyed watching them as we sat on the patio near the pool, and while lounging on the swing and reclining patio chairs. We also enjoyed the easy 20 minute walk to the Botanical Gardens entrance near the Japanese Garden. Oscar's home is so perfect for bird watchers and urban nature lovers like us! We highly recommend Oscar's home!

Private house rentals

Home in Santo Domingo
5 out of 5 average rating, 4 reviews

Comfortable and central apartment

JeanetteRating, 5 stars1 month ago
I loved the space, I’m looking to stay there when I returned it’s safe for children and it’s very welcoming
Guest favorite
Home in Santo Domingo
4.8 out of 5 average rating, 46 reviews

Beautiful near the sea!

JavierRating, 5 stars2 weeks ago
Very good accommodation, comfortable, cozy, clean, tidy, very close to the pier, you can walk there without a problem. Marian was super friendly and attentive. There were quite a few mosquitoes, but it's a matter of going prepared. The only recommendation I would make is to check that the washer and dryer are not a bit damaged. Everything else 10 out of 10
Guest favorite
Home in Santo Domingo
4.78 out of 5 average rating, 50 reviews

Newly remodeled house with free parking

MariRating, 5 stars2 months ago
This is the 3rd time I've stayed and they are always very attentive, many things nearby such as a supermarket, grocery stores, places to eat, nightclub. Anyway, it's always nice to stay in this place
Home in Santo Domingo
5 out of 5 average rating, 3 reviews

Your perfect getaway in the Colonial Zone!

MireilleRating, 5 stars37 months ago
The accommodation is very well-located in the colonial area. Quiet and close to the center. The equipment is quite satisfactory. Nothing is missing. A big thank you to Virginia for her friendly and warm welcome. i recommend this place. The most.. Small grocery store, cafeteria and takeout next door.
Home in Santo Domingo
4.6 out of 5 average rating, 5 reviews

Casa Baez

NancyRating, 5 stars3 months ago
no Encanto el sitio Pero a suggestion to put a few things of ustencili de la cosina example Cordero Larger fridge and three tv en canda how many after all is my good
Home in Santo Domingo Este
4.5 out of 5 average rating, 4 reviews

House in Prolongación Venezuela

Sonia Cristina RosaRating, 5 stars8 months ago
Good accommodation clean bonito finely met my expectation I hope to return soon the excellent cable car stop super nearby walking colmado supermarket etc I like it.
Home in Santo Domingo
5 out of 5 average rating, 3 reviews

Casa de Juanchy – A Modern Colonial Gem

Nathalie JaneRating, 5 stars1 week ago
Juan’s place is a hidden gem in the heart of the Zona Colonial. Everything is within walking distance, making it the perfect spot to explore the area. The Airbnb is well-equipped and features a lovely patio in the back—ideal for relaxing. Even on hot days, the space stays relatively cool, and the peaceful atmosphere makes it a truly restful retreat
Home in Santo Domingo
5 out of 5 average rating, 3 reviews

Historic Home in Zona Colonial

KathrynRating, 5 stars4 months ago
Justin’s place is one of a kind- exactly as pictured- beautiful, airy, artistic, centrally located and the historic sights easily walkable with great food all right there. We visited over the holidays with late night street parties, music and dancing. So fun- if not conducive to good nights sleep- but well worth it! Hosts went out of their ways to accommodate our needs especially allowing late checkout because we had a sick family member who was able to stay behind and rest while we grabbed a last meal. Highly recommended!!

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