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Vacation rentals in De Soto

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Top-rated vacation rentals in De Soto

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A cozy cabin is situated among lush greenery, featuring a spacious deck that extends from the entrance. The gravel driveway leads up to the cabin, surrounded by trees and wild foliage, creating a serene, natural atmosphere.
Cabin in Westby
4.99 out of 5 average rating, 143 reviews

Nature's Nest

Unwind and immerse yourself in nature at this cozy cabin overlooking Timber Coulee Creek. Large living room windows and a spacious deck provide you with a bird’s eye view of the rippling river and many types of wild life. Deer amble through the property; eagles soar and keep an eagle eye on everything. Turkeys, squirrels, coons, and myriad of birds go about their business in this serene environment. Trout fishing is an excellent pastime for those who care to cast a line. Rest, at Nature’s Nest.

Superhost
A hot tub is positioned on a deck, offering views of the Mississippi River and surrounding greenery. The water reflects sunlight, creating a calming atmosphere. The scene includes a bridge in the distance under a partly cloudy sky.
Cabin in De Soto
4.87 out of 5 average rating, 78 reviews

Eagles Nest Hideaway w/outdoor hot tub

This cozy property that overlooks the Mississippi River on 1/2 acre is your next perfect getaway. Having 2 separate buildings to split the group makes this location ideal for families , friend gatherings & fishing trips. Main cabin has 2 bedrooms & 1 bath as well as a full kitchen and hot tub. Garage has an upstairs loft with mini kitchenette , 2 queen size beds, small deck overlooking river & another bathroom. - Hot tub overlooks the Mississippi River & outdoor gas grill in screened in porch

Top guest favorite
The exterior of a modern house is framed by lush green trees, showcasing a multi-level design. A spacious deck is visible with seating arrangements. A smaller building with a dark facade is located nearby, suggesting additional space or utility.
Cabin in De Soto
5 out of 5 average rating, 68 reviews

Driftless Cabin - Sauna, Firepit, BBQ

With central proximity to Viroqua, LaCrosse and Prairie du Chien, experience the Driftless region in style & comfort. Nestled in the woods, 5 mins from the Mississippi, enjoy peace and relaxation with friends and family. Lay back in the sauna and sweat out your stress. Sit by the firepit, share stories and gaze at the star-studded skies. Listen to music in the sunroom and watch birds dart across the backyard. Sway in the hammock and let the sun warm your body. Visit and return rejuvenated.

Guest favorite
Cabin in De Soto
4.83 out of 5 average rating, 63 reviews

Cozy Ridge Retreat

Welcome to the beauty of nature along the Mississippi! This cabin has it all from modern amenities and an authentic log cabin feel to the beautiful soaring views of the Mississippi. You and your guests will enjoy the convenient location, only 12 minutes from Lansing, IA or 7 minutes to the nearest boat landing. Take in the wildlife that frequently passes through the peaceful wooded hillside on the large covered screened porch. Once you arrive you will agree the drive was well worth the visit!

Top guest favorite
A deck with a circular wooden table and two chairs overlooks the water, with trees framing the view of the expansive landscape. The soft hues of dusk provide a serene backdrop to the scene, highlighting the natural beauty of the surroundings.
Cabin in Ferryville
5 out of 5 average rating, 26 reviews

Great River Cabin

Welcome to the mighty Mississippi River, the famous Driftless Area and Great River Cabin. This brand new 2 bedroom 1 bath cabin is fully equipped for a relaxing getaway including 2 private bedrooms, bathroom with walk-in shower, toilet and vanity, kitchenette with stove, full size fridge, microwave and peninsula for dining. There is a TV and futon for extra sleeping space. The jewel of the property is the deck running the full length of the cabin with expansive views of the Mighty Mississippi.

Top guest favorite
Cabin in Ferryville
5 out of 5 average rating, 96 reviews

Aspenshire Cabin: A Nod to English Charm

Aspenshire Cabin is nestled in a valley overlooking a private stream. The Driftless Region is known for its rolling hills and beautiful landscapes. This newly remodeled cabin stands in striking contrast to the woods surrounding it. Inspired by the cozy + sophisticated vibes of Old English Charm, a nod to this design style is evident throughout. Guests are welcomed into a space curated for rest and relaxation, whether through a quiet retreat for the arts or a getaway with family and friends.

Superhost
Tiny home in De Soto
4.89 out of 5 average rating, 111 reviews

Room on the Ridge / HOT TUB / Sleeps 2

Experience a true off the grid stay at this little ridge top room! Everything you need and nothing you don’t-DVDs, books, games, AND hot tub. Enjoy the lovely setting of this romantic escape in nature. Sip your morning coffee in the hot tub, unplug from all the noise and enjoy a breathtaking sunset. The views of the Mississippi are just stunning! Decorated for Christmas mid November through mid January! See all 7 properties with Hot Tubs at Rentals Justin Time.

Guest favorite
A park model home is positioned on a stone terrace, surrounded by lush greenery. Large windows offer expansive views of the surrounding landscape. A wooden deck with seating is visible, extending the living space outdoors, with a tranquil atmosphere conveyed by the scenic backdrop.
Cabin in De Soto
4.96 out of 5 average rating, 143 reviews

Paradise Point sleeps 2 Hot Tub

1 bedroom 1 bath with loft. Cozy home where you can see Paradise. This memorable place is anything but ordinary. Views for miles of the Mississippi River, bluff tops and you can soar with the Eagles. What a place to relax in the newly added hot tub while you enjoy the view in what is call "God's Country". This is promised to be a one of a kind view. The Deck with comfortable outdoor seating Located in the heart of WIsconsin's Driftless Region.

Guest favorite
The cabin's exterior showcases a modern design with a curved roof and a screened-in porch. A relaxing hanging chair is visible, along with outdoor seating. The structure is surrounded by lush greenery and a gently sloping hill, creating a serene atmosphere.
Cabin in Genoa
4.96 out of 5 average rating, 132 reviews

Mee Mee's Cabin Retreat- River, nature, Hot Tub

This Scandinavian inspired farmhouse cabin is located near Genoa, WI. It's unique build is bright and cozy with rustic and eclectic inspirations. Located on the Fuglsang Family Farm with walking trails and a creek that runs through the property. This cabin is perfect for those who seek some quiet and solitude or want to be immersed in the forest, yet a short drive to restaurants or night life. New Hot Tub in November, 2024!!

Guest favorite
A red cabin with a covered porch is seen, featuring a sign that reads 'RIVER VIEW.' The porch is furnished with seating and surrounded by greenery. Nearby, another red cabin structure is visible, set against a backdrop of trees and a clear blue sky.
Cabin in De Soto
4.9 out of 5 average rating, 10 reviews

De Soto Riverview Cabins # 4

Cabin #4 is a two bedroom cabin, fully furnished with kitchen and bath, featuring two (2) queen beds. You'll love the exposed beams and vaulted ceilings. Max occupancy is 4 adults/children. Located in the village of DeSoto, WI. The area offers numerous activities including year round fishing, hiking, seasonal hunting, snowmobile trails, motorcycle riding, bicycling trails, wineries, breweries, Amish Bakeries.

Top guest favorite
A rustic cabin with log siding is set against a clear blue sky. The front porch is covered and features steps leading up to the entrance. Lush greenery surrounds the cabin, with a gravel pathway leading to it. The structure includes two gabled roofs.
Cabin in De Soto
4.96 out of 5 average rating, 76 reviews

Cedar Lookout a top the Mississippi River.

Cedar Lookout a rustic cabin sits above the Mississippi River & is a great place to relax and get away from it all. This quiet little cabin can be a reading place, romantic or cozy get away, family adventure or fishermen's retreat. Just a few miles from the river, small town shopping, a hiking park across the river, fresh air and wildlife.

Guest favorite
The single-story house features a subtle brick exterior and a sloped metal roof. A landscaped garden with a small sign is visible in the front yard, surrounded by a green lawn. Large windows let in natural light, adding to the welcoming appearance.
Home in De Soto
4.98 out of 5 average rating, 47 reviews

Mississippi Escape

Completely remodeled 3-bedroom house in Desoto, WI. Located right off the beautiful, Mississippi. Perfect for a peaceful getaway or outdoor activities. Great for fishing/boating and outdoor recreation. Desoto is located about 5 miles from Lansing, IA, and 30 miles south of La Crosse, WI.

Popular amenities for De Soto vacation rentals

  1. Airbnb
  2. United States
  3. Wisconsin
  4. Vernon County
  5. De Soto