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Vacation rentals in De Soto

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Top-rated vacation rentals in De Soto

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Top guest favorite
The cabin's exterior showcases a blue wooden facade with a metal roof, set against a backdrop of lush greenery. A stone base supports the structure, enhancing its rustic charm. In the foreground, a grassy area is complemented by a few trees, creating a peaceful outdoor environment.
Farm stay in Decorah
4.99 out of 5 average rating, 126 reviews

Footbridge Farm Cabin

Footbridge Farm is a quiet country get-away located on 90 wooded acres, 15 miles NE of Decorah. We are close to the mouth of Canoe Creek, the Upper Iowa River and adjacent to state DNR land. The cozy owner-built cabin has an open ceiling with exposed beams and rafters giving a sense of spaciousness. Local stone was used in the exterior walls and the floor-to-ceiling fire back behind the wood-burning stove. The floors are oak and slate. Detailed craftsmanship can be found throughout the cabin.

Top guest favorite
A cozy cabin is situated among lush greenery, featuring a spacious deck that extends from the entrance. The gravel driveway leads up to the cabin, surrounded by trees and wild foliage, creating a serene, natural atmosphere.
Cabin in Westby
4.99 out of 5 average rating, 110 reviews

Nature's Nest

Unwind and immerse yourself in nature at this cozy cabin overlooking Timber Coulee Creek. Large living room windows and a spacious deck provide you with a bird’s eye view of the rippling river and many types of wild life. Deer amble through the property; eagles soar and keep an eagle eye on everything. Turkeys, squirrels, coons, and myriad of birds go about their business in this serene environment. Trout fishing is an excellent pastime for those who care to cast a line. Rest, at Nature’s Nest.

Top guest favorite
The A-frame cabin is nestled among lush greenery, showcasing a wooden exterior and an inviting deck. A winding driveway leads up to the entrance, framed by trees. Flower boxes adorn the front windows, enhancing the cabin's natural surroundings.
Cabin in Eastman
4.97 out of 5 average rating, 142 reviews

TranquiliTree Cabin- Secluded and Relaxing

Are you looking for a cozy, and quiet get-away spot to rest & relax? Our little Tree house Cabin is the perfect spot! Located between Prairie Du Chien, WI and Ferryville, WI- this little A-frame cabin gets you within 5 min. from the river, but allows you to be tucked in a quiet wooded area. It is 900 sq. ft of pure relaxation & nature! Enjoy your morning coffee in the outdoor room or relax nightly by the fire pit. Disconnect 2 Reconnect. TranquiliTree Cabin is a great place to escape and unwind.

Top guest favorite
A grassy area leads to a wooden deck surrounded by lush greenery and wildflowers under a clear blue sky. The trees and underbrush create a natural backdrop, enhancing the peaceful outdoor setting.
Tiny home in Viroqua
4.99 out of 5 average rating, 177 reviews

Little House on the Pretty! Tiny Home in Woods

Little House on the Pretty(LHP) is part of Sittin Pretty Farm. LHP is tucked into the woods giving a place to retreat and restore. The home is finely crafted embodying a simple elegance and character of the Driftless locale. Once inside, a sense of marvel and serenity are sure make heartfelt memories. We are six miles from Viroqua and nestled among Amish Paradise with several neighboring Amish farms. In season the Amish have roadside vegetable stands where you can purchase veggies and pie!

Top guest favorite
A charming farmhouse is nestled among lush greenery, surrounded by tall trees. The two-story structure features a gabled roof and a covered front porch. Natural landscaping, including shrubs and grass, frames the house, creating a serene and private atmosphere amidst the forested hills.
Cabin in Gays Mills
4.98 out of 5 average rating, 350 reviews

Driftless Region Cabin/ Stream and Sauna

Settle into a quaint farmhouse nestled in a valley in the rolling, forested hills of the Driftless Region. Start your day with a cup of local coffee on the front porch. Go on a long walk or bike ride, then return to the cottage to cook, play board games, listen the record collection or visit Viroqua (25 minutes) for a farm-to-table 5-star dinner, or check out local music. Build a warm fire outdoors/ warm up by the gas stove indoors, or go down to the stream for a sauna by the cool water creek.

Top guest favorite
A covered porch features comfortable seating with a dark wicker sofa and a matching armchair. A gas grill is positioned nearby, with lush greenery and shrubs creating a natural border around the space. The wooden deck offers a peaceful view of the surrounding fields.
Cottage in Viroqua
4.99 out of 5 average rating, 138 reviews

Lovely Country Cottage Near Viroqua.

Located at the end of a quiet, paved country road, The Garden Cottage is just six miles west of Viroqua, Wisconsin. You'll find everything you need for a comfortable stay, all on one level, including a king-sized bed, nice kitchen, gas grill, large bathroom, walk-in tile shower, a flat-screen TV with a DVD player, Roku, movies, good cell phone reception and high-speed fiber optic internet. All linens, soaps, coffee, tea, and kitchen utensils are provided. The songbirds and views are amazing.

Top guest favorite
A rustic A-frame cabin is situated amidst bare trees, with a wrap-around deck and a view of the sprawling landscape. A vibrant sunset casts shades of orange and purple across the sky, reflecting on the nearby river below, enhancing the tranquil setting.
Cabin in De Soto
4.94 out of 5 average rating, 103 reviews

Rustic Ridge Chalet, hot tub & amazing river view!

Kick back and relax in this calm, stylish space. This recently purchased and renovated cabin is exactly where you want to be! * Hot Tub * River View * Privacy * King bed in loft * Queen murphy bed * 2 bathrooms * Cable TV, 2 smart TV's , Wi-Fi * Wrap around deck * Fire pit * Gas stove fireplaces, just flip switch * Kitchen items included (cookware, etc) * Gas grill * Bed & bath linens supplied * Games, books * PEACE & QUIET * We do allow dogs ($110/stay) max 2 dogs. NOT LEFT UNATTENDED

Superhost
The log cabin is set amidst a vibrant landscape of autumn foliage, showcasing a mix of green, orange, and yellow trees. The property is partially surrounded by open grassy areas and stands out against the backdrop of rolling hills under a cloudy sky.
Cabin in De Soto
4.89 out of 5 average rating, 112 reviews

Murph's: Cozy 3BR/2BA cabin w/ hot tub + fireplace

Murph's Hideaway is a log cabin located high on the bluffs overlooking the Mississippi River valley. This three-bedroom/two-bathroom property features a full kitchen and living room, finished basement, a large deck, charcoal grill (you supply the charcoal and lighter fluid) and hot tub! Enjoy the spectacular sunsets, hike the woods and relax by the gas fireplace. - Our hot tubs operate year-round - Pets are allowed, but must be preapproved, and there is a separate, nonrefundable pet fee

Superhost
A spacious living room features a modern fireplace with a black brick surround. Comfortable seating options include a gray sofa and colorful armchairs. A wooden coffee table sits centrally, while a large television is mounted on the wall. Light filters in through sliding glass doors, enhancing the room's inviting ambiance.
Cottage in Stoddard
4.91 out of 5 average rating, 303 reviews

Stylish 1 bedroom cottage on the Mississippi River

This unique place has a style all its own. Conveniently located by the Mississippi River and highway 35. The place gives you a cabin feel close to La Crosse! 15 minute drive to downtown La Crosse and 3 miles North of Stoddard puts you in a great central location for the area. Mt. La Crosse is super close to enjoy skiing/snowboarding. Goose Island is 5 minutes away. Great spot for bird watching, fishing, kayaking, boat launches, hiking or frisbee golf. Pets are welcome. No cleaning fee!

Guest favorite
Cabin in De Soto
4.92 out of 5 average rating, 130 reviews

Barn On The Ridge / HOT TUB / Sleeps 6

Kick back & relax in this cozy, stylish cabin with beautiful river views during all seasons. Enjoy evening dinners on the screened in porch, sip your coffee from the upper deck & unwind in a luxurious hot tub! This loft style cabin was crafted in 2020 & has sleeping space for up to 6 guests, featuring a king bed, full size bed & full size futon. You’ll be minutes from De Soto & Lansing area and only 30 minutes to the La Crosse area! Hosted with Love, Rentals Justin Time.

Top guest favorite
The interior of the silo guesthouse features a circular design with wooden beams overhead. A cozy seating area includes a large sectional sofa and a stylish ottoman. Natural light enters through multiple windows, enhancing the space, while a staircase leads to a loft area.
Farm stay in Caledonia
4.99 out of 5 average rating, 103 reviews

Silo Loft Guesthouse

Our silo guesthouse provides a beautiful country retreat surrounded by hundreds of acres of woods and farm land. This working dairy farm is the perfect stay for a tranquil get away or the full dairy farm experience. If you’re looking for a CLEAN, peaceful & unique stay, this is the place for you! Recent guests say it’s the “hidden gem” of MN! Just 10-30 minutes from local coffee shops, restaurants, and many outdoor activities, this getaway has something for everyone!

Top guest favorite
A serene view of the Mighty Mississippi River is captured during sunset. Soft hues of orange and purple fill the sky, while the landscape is framed by lush green trees and gentle mists rising from the water, creating a tranquil atmosphere.
Home in Lynxville
4.85 out of 5 average rating, 250 reviews

Highland Hideaway

A cozy, secluded two bedroom cabin located in the driftless region with incredible views of the Mighty Mississippi!!! If your looking for peace, quiet, and beautiful sunsets this is your place. Only 20 minutes from Wyalusing state park, The Effigy Mounds (sacred Indian Burial Grounds) Pikes Peak and Historic Villa Louis. This beautiful cabin centers you 30 miles from amazing hiking, fishing, hunting and nature for a weekend of disconnecting from busy life.

Popular amenities for De Soto vacation rentals

Quick stats about vacation rentals in De Soto

  • Total vacation rentals

    Explore 20 vacation rentals in De Soto

  • Nightly prices starting at

    De Soto vacation rentals start at ﺩ.ﺇ257 per night before taxes and fees

  • Verified guest reviews

    Over 610 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Wi-Fi availability

    10 of De Soto vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across De Soto rentals

  • 4.9 Average rating

    De Soto stays are highly rated by guests—averaging 4.9 out of 5!

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  5. De Soto