Vacation rentals in Darlington County

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Top-rated vacation rentals in Darlington County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A comfortable living area features a dark gray sofa complemented by two accent pillows. A coffee table is positioned in front of the seating, and two standing lamps provide soft lighting. A simple wall art above the sofa adds a touch of elegance to the space.
Home in Florence
4.98 out of 5 average rating, 126 reviews

Renovated 2 BR/2 B Townhouse Cozy & Clean

Keep it simple at this peaceful, centrally-located, and renovated townhouse close by I-95 and I-20 and within 15 mins. to the Florence Center, downtown Florence, many restaurants, and McLeod and MUSC Florence. House is located in a safe neighborhood with 2 queen beds and 1 sofa bed in the living room. Enjoy being outdoors? Relax outdoors on your own private patio, go on a walk around the neighborhood, or go on an adventure. The Rail Trail & Ebenezer Park are minutes away. Utilities included.

Top guest favorite
A single-story home is shown with a welcoming front porch and bright red door. The exterior is accented by black shutters and a white facade, surrounded by a grassy lawn with small trees. A clear blue sky with soft clouds is visible in the background.
Home in Hartsville
4.99 out of 5 average rating, 159 reviews

Manchester Place

Hartsville is a Charming Town with plenty of family activities, shops, and dining. Home is located in the quiet Fox Hollow subdivision which is just outside the city limits but still close to downtown. Robinson Nuclear Plant 10 min. Sonoco 7 min. Coker University 7 min. Downtown Hartsville 7 min. Carolina Pines Hospital 9 min. McLeod Hospital Florence 42 min. Byerly Park 9 min. Hartsville Center Theater 6 min. Governor's School for Science and Mathematics 9 min. Darlington Raceway 22 min.

Superhost
A bright living area is furnished with a light-colored sofa adorned with accent pillows. In front, a wooden coffee table rests on a soft area rug. The kitchen is visible in the background, showcasing modern appliances and an open layout that enhances the space's inviting feel.
Apartment in Florence
4.88 out of 5 average rating, 406 reviews

Kuker Carriage House-Sleeps 3-Downtown/Near I95&20

Kuker Carriage House was originally a barn that has been converted into apartments in the heart of the newly revitalized Florence downtown. This first floor unit was just fully renovated and is ready for you to enjoy, whether for a short overnight stop or a longer extended stay. This space is bright and open with lots of natural light and a fully enclosed private courtyard. Queen bed, twin daybed, full bath, Wifi and TV. Walkable to parks and restaurants. Just 4 miles from I95 and I20

Guest favorite
A bright living area features a light-colored sectional sofa arranged around a circular coffee table. Natural light enters through the windows, enhancing the warm ambiance. A simple desk with a chair is positioned nearby, complementing the overall spaciousness of the room.
Home in Florence
4.93 out of 5 average rating, 107 reviews

Charming Home in Florence, SC

Welcome to Florence, South Carolina! This inviting 3-bedroom, 2-bathroom home is a haven of comfort and convenience. With four queen beds, it comfortably accommodates a group of friends or family. Step into the fully stocked kitchen, relax in the cozy living space, equipped with smart TVs for entertainment. The fenced backyard offers both privacy and a secure play area for your furry friends. Enjoy outdoor gatherings at the picnic table. Convenient amenities include a washer and dryer.

Top guest favorite
Apartment in Hartsville
5 out of 5 average rating, 21 reviews

Private apartment minutes from Darlington Raceway

Enjoy a peaceful stay at this quaint 2-bedroom apartment in the countryside of Hartsville. The cozy space features 2 queen beds, 2 full bathrooms, and essential amenities like a washer/dryer, smart TV, and WiFi. Experience what Hartsville has to offer with a stay at our welcoming apartment. Walk out of the front door to a beautiful view of our pond. Owners live in the main house of the property, but you will have access to a private apartment with it's own entrance in a separate building.

Top guest favorite
A well-appointed sleeping area contains two beds, each dressed in light-colored bedding with decorative throws. A bedside lamp is positioned between the beds on a dark nightstand. Natural light enters through partially covered windows, highlighting the room's neutral tones and horse-themed wall art.
Barn in Society Hill
4.95 out of 5 average rating, 385 reviews

Burchs Carriage House

Private carriage house sitting adjacent to the most historic estate home in the lovely town of Society Hill. Separate entrance for guests which accommodates large horse trailers. Property caters to all animals! Kitchenette (microwave, toaster oven and hot plate), washer/dryer, Apple TV and wifi. Continental breakfast, wine/snacks provided. BBQ grill also. 2 stalls with paddocks. 12 x 12 and 10 x 12. Rooms are as they would be at your own home, separate from each other. See photo 13.

Top guest favorite
The cozy interior features rustic wooden beams and a blend of warm tones. A spacious bed is positioned against a wall with a peacock artwork. A kitchenette area is visible, alongside a small dining table and a television, providing a comfortable, multifunctional living space.
Farm stay in Timmonsville
4.95 out of 5 average rating, 716 reviews

The Cottage at Dream Acres & Petting Zoo I-95/I-20

The Cottage at Dream Acres is situated with its own private drive on our 8 acre working horse farm located near Florence SC at the I-20/ I-95 corridor, 5 mins off the highway. We are the 1/2 way point between NY & FL. Relax and unwind from a long roadtrip or take a weekend farm-stay getaway. All the amenities of a larger home with the convenience of a smaller space! Family Friendly; sleeps up to 4, newly renovated in 2020, petting zoo, outdoor fire pit, tree swing, picnic table!

Guest favorite
A living area is shown featuring a large brown sectional sofa with decorative pillows. A green coffee table sits on a light-patterned rug, with a television displaying an underwater scene. The space is illuminated by soft lighting from a dining area visible in the background.
Guesthouse in Florence
4.98 out of 5 average rating, 919 reviews

Boho Private Downtown Stay Near I-95 & Hospital

Comfort, cleanliness, privacy, and personality! Perfect for overnight stays or longer terms. Come enjoy our Boho hideaway in the heart of Florence. Our place has all the amenities of a hotel with the comfort and privacy of your own home including covered parking for two vehicles. We are located within walking distance to downtown Florence and a 5 minute drive to all of the restaurants and shopping that Florence has to offer. Come stay at our guest house and make yourself at home!

Guest favorite
Condo in Florence
4.91 out of 5 average rating, 87 reviews

Governor's Square at Coventry @ I-20/I-95

This private, cozy two bedroom 1 1⁄2 bath condo has recently been renovated and is discounted for longer stays. The condo includes 2 bedrooms. It's located among quiet neighborhoods for peaceful walks or for sitting outside on the private patio. Within five minutes you’ll find access to I-20 & I-95, restaurants, malls, civic center, movie theater, Florence rail trail and parks, golfing, tennis, soccer and more. Highway 76 is two miles away and takes you directly to Myrtle Beach.

Top guest favorite
A retro camping trailer is displayed under a shaded awning, featuring a sleek metallic exterior. Two red adirondack chairs are positioned on a checkered outdoor mat, creating a relaxed seating area. Lush greenery surrounds the trailer, enhancing the outdoor setting.
Camper/RV in Florence
4.98 out of 5 average rating, 57 reviews

'Cardinals Retreat'

Escape to Serenity: Nestled within walking distance to a peaceful creek, this Airbnb offers a tranquil escape from the everyday. This charming retro 21' camping trailer boasts 1 bedroom (full size bed), a small kitchen, including cooktop, microwave, and sink. The living area has a u-shaped couch which can also sleep a child comfortably. A bathroom with shower, along with 1 smart tv with wi-fi. Outside, the creek setting provides ample opportunities for outdoor relaxation.

Top guest favorite
A charming poolside cottage is surrounded by lush palm trees and vibrant plants. The outdoor space features a dining set on a paved patio, providing a tranquil area for relaxation. The entrance to the cottage is easily accessible, enhancing the inviting ambiance.
Guesthouse in Florence
4.94 out of 5 average rating, 931 reviews

Cottage by the Pool: Close to Interstates

Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, full sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.

Top guest favorite
The exterior of the house features a cozy entrance with wooden double doors. The façade displays a blend of light brick and dark shutters. A driveway leads to two garages on the side, while the front yard is landscaped with minimal vegetation.
Home in Florence County
5 out of 5 average rating, 203 reviews

Highway Oasis and Myrtle Beach

Welcome to this charming new house ideally situated close to both a major highway i 95 and i20 and the serene Myrtle beach, offering the perfect blend of convenience . Nestled in a great neighborhood, this residence boasts easy access to shopping center, ensuring that all your daily needs are just moments away. Very close to Florence Civic Center, 15 minutes to Buc-ee's Myrtle beach in 1 hr of a drive and shopping amenities.

Popular amenities for Darlington County vacation rentals