Vacation rentals in Darlington County

5 out of 5 average rating, 117 reviews

Manchester Place

Hartsville is a Charming Town with plenty of family activities, shops, and dining. Home is located in the quiet Fox Hollow subdivision which is just outside the city limits but still close to downtown. Robinson Nuclear Plant 10 min. Sonoco 7 min. Coker University 7 min. Downtown Hartsville 7 min. Carolina Pines Hospital 9 min. McLeod Hospital Florence 42 min. Byerly Park 9 min. Hartsville Center Theater 6 min. Governor's School for Science and Mathematics 9 min. Darlington Raceway 22 min.

4.9 out of 5 average rating, 356 reviews

Apartment in Florence

Kuker Carriage House-Sleeps 3-Downtown/Near I95&20

Kuker Carriage House was originally a barn that has been converted into apartments in the heart of the newly revitalized Florence downtown. This first floor unit was just fully renovated and is ready for you to enjoy, whether for a short overnight stop or a longer extended stay. This space is bright and open with lots of natural light and a fully enclosed private courtyard. Queen bed, twin daybed, full bath, Wifi and TV. Walkable to parks and restaurants. Just 4 miles from I95 and I20

4.95 out of 5 average rating, 101 reviews

Bungalow in Hartsville

The Pelican House | 2-bdrm in H-ville w/King Bed!

The Pelican House is in downtown Hartsville, walking distance to Sonoco & Coker University. The main bedroom features a comfy king bed, 2nd bedroom has 2-twin beds, & additional sleeping is available on the flip out queen sofa bed in the living room. Sit & rock on the front porch, grill out on the propane grill, make meals in the stocked kitchen, or walk downtown to restaurants, bars, & shops. Kitchen table has seating for up to six. Covered parking is offered in the connected carport.

Farm stay in Timmonsville

4.95 out of 5 average rating, 636 reviews

The Cottage at Dream Acres & Petting Zoo I-95/I-20

The Cottage at Dream Acres is situated with its own private drive on our 8 acre working horse farm located near Florence SC at the I-20/ I-95 corridor, 5 mins off the highway. We are the 1/2 way point between NY & FL. Relax and unwind from a long roadtrip or take a weekend farm-stay getaway. All the amenities of a larger home with the convenience of a smaller space! Family Friendly; sleeps up to 4, newly renovated in 2020, petting zoo, outdoor fire pit, tree swing, picnic table!

4.98 out of 5 average rating, 817 reviews

Guesthouse in Florence

Boho Private Downtown Stay Near I-95 & Hospital

Comfort, cleanliness, privacy, and personality! Perfect for overnight stays or longer terms. Come enjoy our Boho hideaway in the heart of Florence. Our place has all the amenities of a hotel with the comfort and privacy of your own home including covered parking for two vehicles. We are located within walking distance to downtown Florence and a 5 minute drive to all of the restaurants and shopping that Florence has to offer. Come stay at our guest house and make yourself at home!

4.83 out of 5 average rating, 127 reviews

Quaint 2BR home w access to Black Creek & downtown

Our freshly renovated home sits in a family-oriented neighborhood only a mile from downtown Hartsville and Kalmia Gardens and includes access to Black Creek. This 600 sf home features 2 bedrooms, 1 bath, a full kitchen, washer and dryer and an open living area. Digital antenna reception for smart-tv and high speed wi-fi internet. Small dogs will be considered for stays on a case-by-case basis. Pet stays require prior approval from the hosts and will involve additional fees.

4.93 out of 5 average rating, 845 reviews

Guesthouse in Florence

The Cottage by the Pool: Close to Interstates

New floors and paint in January of 2023. Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, full sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.

4.84 out of 5 average rating, 123 reviews

Home in Darlington

Located 100 feet from The Darlington Raceway!

This cute little bungalow is located across the street from The Darlington Raceway. Just a few steps puts you at the door of the famous Joe Weatherly Stock Car Museum. We are also within walking distance to Manheim Auto Auction. The Raceway Grill, a favorite of Dale Earnhardt, is located across the street ! If you are here during the week, South of Pearl, Darlington's finest eating establishment, is located in uptown Darlington. WE DO NOT HAVE A STOVE OR WASHER/DRYER

4.97 out of 5 average rating, 123 reviews

Cozy little home away from home

This little gem is sure to make you feel at home! Our Barefoot Bungalow sits on a quiet residential street just 3 minutes from downtown Hartsville. The beds are comfortable, the couch is just waiting for you to settle in, and the kitchen was set up by two people who LOVE to cook. There's even an outdoor space to have a quick meal or enjoy the cool of the evening. This is my little dream cottage and I am so happy to be able to share it with you!

4.96 out of 5 average rating, 85 reviews

Home in Florence

Pineapple House Historic Southern Charm Downtown

Experience southern hospitality in this historic charmer perfect for professionals. -Quaint, quiet downtown neighborhood walkable to restaurants -Fast wifi, laundry room, large fenced backyard w/ fire pit, off-street parking -Fully loaded kitchen, 2 Roku TV's, queen sleeper sofa, relaxing front porch -3 min to FMU Performing Arts Center, 5 min to McLeod Hospital, 10 min to FMU & MUSC Medical Center. -Perfect for short or long stays!

5 out of 5 average rating, 126 reviews

Home in Florence County

Highway Oasis and Myrtle Beach

Welcome to this charming new house ideally situated close to both a major highway i 95 and i20 and the serene Myrtle beach, offering the perfect blend of convenience . Nestled in a great neighborhood, this residence boasts easy access to shopping center, ensuring that all your daily needs are just moments away. Very close to Florence Civic Center, 15 minutes to Buc-ee's Myrtle beach in 1 hr of a drive and shopping amenities.

4.82 out of 5 average rating, 327 reviews

Cottage in Darlington

Darlington Farm House Near I-95 & Florence

Nicknamed the "Little House," this charming old farm house has been family owned since the early 1800s. The house is located on 3 acres of land with a small pond. Fully renovated interior includes a kitchen with new appliances. Convenient location less than 10 minutes from I-95. Experience country living at its finest, perfect to break up a long drive, visit relatives, or just get some good old peace and quiet.

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Popular amenities for Darlington County vacation rentals

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Other great vacation rentals in Darlington County

Guesthouse in Timmonsville

4.86 out of 5 average rating, 70 reviews

New camper with memory foam mattress on 1/2 acre

KristaRating, 5 stars2 weeks ago

Takisha’s place was a good spot to stop at off the highway and get some much needed rest.

Apartment in Darlington

5 out of 5 average rating, 12 reviews

Eagle’s Nest Long Stay rental Apartment

MadelynRating, 5 stars14 months ago

I initially chose this Airbnb because of its location (it was the closest I found to my clinical rotation in Darlington) and I am SO grateful I did because it was one of the best Airbnb experiences I've ever had. Upon arriving, Bill & Wanda met me, gave me a tour of where I would be staying, and brought along some delicious muffins. They both are so friendly and warm, right away you feel like you've known them your whole life. The Airbnb itself is nothing short of perfect, Bill & Wanda really outdid themselves. The space they carefully curated met all my needs during my stay and they continually went out of their way to make me feel at home. I immediately felt comfortable and at ease, which is not usual for me when when staying in a new place. I also loved the neighborhood was serene, private, and safe. Bill and Wanda are just wonderful people and embody what Airbnb is all about. I recommend Eagle's Nest to EVERYONE traveling to the Darlington/Florence area. I will definitely be back!

5 out of 5 average rating, 11 reviews

Home in Florence

Cozy One Story Town House

AngelaRating, 5 stars1 week ago

Love Chris & Ally Place. They Are Very Nice People & Great Communication. Such A Great Peaceful, Clean Place & Area. Everything As Described! My Family & I Will Definitely Visit This Place Again. Thank You For Have Us!

Guest suite in Florence

4.84 out of 5 average rating, 483 reviews

Private Apartment 5 Min Away From I-95 & I-20

K A TRating, 5 stars2 days ago

Quran's place was precisely as described and more. Very homey and quiet. The bed was very comfortable and restive after a long journey. It was exactly as described but had that extra charm to make you feel relaxed. Quran is a very gracious host as well, helping us when we accidently locked ourselves out; very kind. Will hope to book Quran's place again on our repeat journey to visit family in the South. Thank you!!

5 out of 5 average rating, 5 reviews

Historic Lakeside Retreat

JimRating, 5 stars2 weeks ago

Great location, right in the lake. Very nice host and easy to communicate with. Don’t miss out on this opportunity if you are in the area looking for somewhere to stay.

Guesthouse in Darlington

5 out of 5 average rating, 5 reviews

The Haven of Rest Pool House.

JoannaRating, 5 stars2 days ago

Perfect place for my husband and me to stay while dealing with a difficult family situation. Very sweet couple, lovely guest house. Comfortable and clean. It is our go-to spot any time we need to visit family from now on.

4.98 out of 5 average rating, 48 reviews

Apartment in Florence

Hadley's Hideaway

LundonRating, 5 stars2 months ago

I cannot speak highly enough about Erika and her place at Hadleys Hideaway!!! She made sure to make us feel at home and was so wonderful in all of the little details! The home itself is BEYOND cute and thoughtfully decorated and taken care of, and the host being so incredible was the cherry on top! We will absolutely be coming back again!!