Vacation rentals in Darlington County

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Top-rated vacation rentals in Darlington County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A comfortable living area features a dark gray sofa complemented by two accent pillows. A coffee table is positioned in front of the seating, and two standing lamps provide soft lighting. A simple wall art above the sofa adds a touch of elegance to the space.
Home in Florence
4.99 out of 5 average rating, 138 reviews

Renovated 2 BR/2 B Townhouse Cozy & Clean

Keep it simple at this peaceful, centrally-located, and renovated townhouse close by I-95 and I-20 and within 15 mins. to the Florence Center, downtown Florence, many restaurants, and McLeod and MUSC Florence. House is located in a safe neighborhood with 2 queen beds and 1 sofa bed in the living room. Enjoy being outdoors? Relax outdoors on your own private patio, go on a walk around the neighborhood, or go on an adventure. The Rail Trail & Ebenezer Park are minutes away. Utilities included.

Top guest favorite
Tiny home in Timmonsville
5 out of 5 average rating, 51 reviews

The Hideaway at Fox Fields

The Hideaway at Fox Fields tiny home sleeps up to 4 with one bedroom and a sleeper sofa (both queen size beds). The bathroom has a walk-in shower. There's full kitchen with dishwasher, oven, microwave, and dishes, plus a washer/dryer combo. There's TV (guests use their own streaming accounts), game cabinet, and two mini-split AC units. The front porch overlooks a pond; cows are in the pasture at times. Located 10 minutes from I-20 Exit 137 and 5 minutes from The Cabin at Old Spur wedding venue.

Guest favorite
The cottage is softly illuminated by string lights, creating a serene atmosphere in the yard. A charming fountain adds a soothing element to the outdoor space, complemented by a patio area featuring a red umbrella and a table among well-maintained greenery.
Guesthouse in Hartsville
4.88 out of 5 average rating, 56 reviews

Private Cottage, Guesthouse, Queen Bed & Kitchen

Charming, peaceful cottage just a short walk from downtown Hartsville. Ideal for work, visits to local schools, or a relaxing getaway. • Private driveway • Fast WiFi & workspace • Smart TVs & games • Fully equipped kitchen • Snacks, tea & coffee • In-house laundry • Outdoor seating • Dog-friendly We kindly ask that any pets are disclosed in your reservation. The pet fee helps cover additional time & care needed to clean so we may continue offering a pet-friendly space for all guests.

Top guest favorite
A single-story home is shown with a welcoming front porch and bright red door. The exterior is accented by black shutters and a white facade, surrounded by a grassy lawn with small trees. A clear blue sky with soft clouds is visible in the background.
Home in Hartsville
4.98 out of 5 average rating, 181 reviews

Manchester Place

Hartsville is a Charming Town with plenty of family activities, shops, and dining. Home is located in the quiet Fox Hollow subdivision which is just outside the city limits but still close to downtown. Robinson Nuclear Plant 10 min. Sonoco 7 min. Coker University 7 min. Downtown Hartsville 7 min. Carolina Pines Hospital 9 min. McLeod Hospital Florence 42 min. Byerly Park 9 min. Hartsville Center Theater 6 min. Governor's School for Science and Mathematics 9 min. Darlington Raceway 22 min.

Guest favorite
Cottage in Florence
5 out of 5 average rating, 15 reviews

Pointe Experience

Welcome to the epitome of comfortable living! This luxurious 2-bedroom, 2-bathroom townhome, nestled in the charming Chandler Pointe subdivision, offers the perfect blend of convenience and style. Ideal for those seeking temporary accommodation, this fully furnished townhome leaves no detail untouched. Inside, you'll find a thoughtfully designed space adorned with quality furniture, artwork, lamps, and cozy rugs, creating an ambiance that truly feels like home. this peaceful place to stay.

Top guest favorite
The cozy interior features rustic wooden beams and a blend of warm tones. A spacious bed is positioned against a wall with a peacock artwork. A kitchenette area is visible, alongside a small dining table and a television, providing a comfortable, multifunctional living space.
Farm stay in Timmonsville
4.95 out of 5 average rating, 752 reviews

The Cottage at Dream Acres & Petting Zoo I-95/I-20

The Cottage at Dream Acres is situated with its own private drive on our 8 acre working horse farm located near Florence SC at the I-20/ I-95 corridor, 5 mins off the highway. We are the 1/2 way point between NY & FL. Relax and unwind from a long roadtrip or take a weekend farm-stay getaway. All the amenities of a larger home with the convenience of a smaller studio space! Family Friendly; sleeps up to 4, newly renovated in 2020, petting zoo, outdoor fire pit, tree swing, picnic table!

Top guest favorite
Apartment in Hartsville
5 out of 5 average rating, 26 reviews

Private apartment minutes from Darlington Raceway

Enjoy a peaceful stay at this quaint 2-bedroom apartment in the countryside of Hartsville. The cozy space features 2 queen beds, 2 full bathrooms, and essential amenities like a washer/dryer, smart TV, and WiFi. Experience what Hartsville has to offer with a stay at our welcoming apartment. Walk out of the front door to a beautiful view of our pond. Owners live in the main house of the property, but you will have access to a private apartment with it's own entrance in a separate building.

Superhost
Guest suite in Florence
4.83 out of 5 average rating, 522 reviews

Private Apartment 5 Min Away From I-95 & I-20

Please come and enjoy our Guest Apartment in Florence, SC! A great stop for travelers to rest during their trips. Guests will have a private entrance to the apartment that is attached but separate from the main house, where my family and I live. Guest privacy will always be respected. One bedroom has a queen size bed, a second bedroom has a single. The bathroom has a tub and shower. The kitchen has a stove/oven. The apartment is cleaned and sanitized after each guest leaves. Thank you!

Top guest favorite
A living area is shown featuring a large brown sectional sofa with decorative pillows. A green coffee table sits on a light-patterned rug, with a television displaying an underwater scene. The space is illuminated by soft lighting from a dining area visible in the background.
Guesthouse in Florence
4.98 out of 5 average rating, 956 reviews

Boho Private Downtown Stay Near I-95 & Hospital

Comfort, cleanliness, privacy, and personality! Perfect for overnight stays or longer terms. Come enjoy our Boho hideaway in the heart of Florence. Our place has all the amenities of a hotel with the comfort and privacy of your own home including covered parking for two vehicles. We are located within walking distance to downtown Florence and a 5 minute drive to all of the restaurants and shopping that Florence has to offer. Come stay at our guest house and make yourself at home!

Guest favorite
Condo in Florence
4.91 out of 5 average rating, 104 reviews

Governor's Square at Coventry @ I-20/I-95

This private, cozy two bedroom 1 1⁄2 bath condo has recently been renovated and is discounted for longer stays. The condo includes 2 bedrooms. It's located among quiet neighborhoods for peaceful walks or for sitting outside on the private patio. Within five minutes you’ll find access to I-20 & I-95, restaurants, malls, civic center, movie theater, Florence rail trail and parks, golfing, tennis, soccer and more. Highway 76 is two miles away and takes you directly to Myrtle Beach.

Top guest favorite
The bedroom features a spacious bed with decorative pillows, flanked by two bedside tables with lamps. Soft lighting creates a calming ambiance. A door leads to an adjoining space, while light walls enhance the feeling of openness.
Guest suite in Timmonsville
5 out of 5 average rating, 81 reviews

Private Suite Sleeps 3 Near I-20 & I-95

A newly renovated peaceful, rural retreat minutes from I-95/I-20 with quick access to Florence and Timmonsville. Luxurious memory-foam queen bed, deep soaking tub, separate shower, Keurig coffee bar, mini-fridge, snacks & private porch. Sleeps 3 (with optional sleeper sofa). Trucks & small trailers welcome. Infant pack-n-play available. DoorDash delivers. Flexible check-in/out available. Top 5% Superhost. We look forward to hosting you!

Top guest favorite
A charming poolside cottage is surrounded by lush palm trees and vibrant plants. The outdoor space features a dining set on a paved patio, providing a tranquil area for relaxation. The entrance to the cottage is easily accessible, enhancing the inviting ambiance.
Guesthouse in Florence
4.94 out of 5 average rating, 977 reviews

Cottage by the Pool: Close to Interstates

Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, full sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.

Popular amenities for Darlington County vacation rentals