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Villa vacation rentals in Colón Province

Find and book unique villas on Airbnb

Top-rated villa rentals in Colón Province

Guests agree: these villas are highly rated for location, cleanliness, and more.

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Superhost
A welcoming private villa is surrounded by tall trees, showcasing a spacious layout. A swimming pool and trampoline are visible in the backyard, and the exterior features large windows allowing natural light. A green pathway leads to the entrance, emphasizing the serene, forested environment.
Villa in Panamá
4.79 out of 5 average rating, 24 reviews

Spacious Mountain Getaway in Paradise Cloud Forest

Private Villa located at Chagres National Park; a rainforest reserve only 30 minutes away from the airport and 50 minutes from Panama City. At 1,007 meters altitude, you will enjoy the perfect climate, bird watching, beautiful river walks, waterfalls, and many hiking trails full of wildlife, enjoy our mountain's pure air or simply relax in Nature. Bring the whole family to this great place with lots of room for fun. Bring your pets our land is completely fenced, they can run free in a vast space

Guest favorite
Villa in Palenque
5 out of 5 average rating, 28 reviews

All 5 Stars Reviews Caribbean Retreat Beach Front

If you are looking for a place to relax this is it. Located 2 and a half hours away from Panama City, this is a place to enjoy the beach while listening to the sound of the waves. In a luxurious villa. The place is ideal for families with kids. Very save with shallow waters as well with deeper areas. Our large gardens are also ideal for kids to play. Kayaks are included. We have high speed internet, which will allow you to work from here. We also have kayaks and paddle boards for our guest.

Top guest favorite
An aerial view reveals a private pool surrounded by lounge chairs and a vibrant garden. Nearby, a game area with a pool table and a basketball court features colorful walls. The layout emphasizes spaciousness, ideal for relaxation and entertainment.
Villa in Panamá
4.96 out of 5 average rating, 25 reviews

Villa El Cangrejo

Bienvenidos a Villa El Cangrejo, un refugio premium en el corazón de la ciudad. Con 800 m², esta propiedad es ideal para 14 personas. Ofrece 7 dormitorios, 7 baños, cocina completamente equipada, piscina, gimnasio y cancha de baloncesto. Disfruta de una sala de cine privada, amplia terraza de 200 m², patio frontal de 50 m², mesa de ping-pong, air hockey, videojuegos, dardos, futbolito, juegos de mesa y wifi. Vive una estadía inolvidable en un ambiente acogedor y completamente equipado.

Guest favorite
A multi-story mansion is showcased overlooking a vibrant swimming pool, adorned with inflatable toys including a pink flamingo and a whale. Bright umbrellas provide shade over red loungers, all set against a backdrop of lush greenery and a partially cloudy sky.
Villa in Panamá
4.96 out of 5 average rating, 70 reviews

Breathtaking Views Mansion w/King Beds

Book your next thrilling Panama City vacation at our dreamy 11,500 sq. foot multi-story family mansion, superbly located on a hilltop high above the metropolis in this affluent neighborhood. Ideal for longer stays. Discover the vibrant buzz of Cinta Costera or explore the UNESCO world heritage sites at Casco Viejo – all under 5 km away from your doorstep. Enjoy a refreshing dip into the swimming pool and admire the sublime views of the Panama City Skyline from our unique roof terrace.

Guest favorite
Villa in Punta Chame
4.92 out of 5 average rating, 38 reviews

Beachfront | Rooftop | Amazing Villa in PuntaChame

Relax in this spacious beachfront villa with a private pool, rooftop terrace, and palm-lined path straight to the beach. Perfect for families, groups, or special events — whether you’re sharing BBQ nights, watching sunsets on the rooftop, or simply soaking up the tropical atmosphere. Just 2 hours from Panama City and right in front of the beach! • Beachfront Villa with Direct Access • Private Pool + Palm Garden • Rooftop with 360° Sunset Views • Fast Wi-Fi & Dedicated Workspace

Top guest favorite
An inviting infinity pool overlooks a stunning coastal view. A spacious seating area, featuring colorful cushions, complements the serene atmosphere. Natural light fills the space, enhancing the connection to the outdoors, while the blue waters of the pool blend seamlessly with the distant ocean.
Villa in Cacique
4.98 out of 5 average rating, 55 reviews

FACING THE SEA Cacique (Portobello Park)

A house! A real glass island in the heart of the jungle! In the middle of the Portobello National Park (access only by 4x4 AWD) nestled at the top of the hill, between sky/sea, away from all eyes, a transparent house where glass embraces nature on all sides creating a unique connection between the inside and the outside, ideal for resting, disconnecting, comfortable, spacious, cool (central air conditioning), exclusive. It is the witness of a grandiose spectacle that awaits you!

Guest favorite
A spacious swimming pool is framed by lounge chairs, with a bright pink float positioned in the water. The villa's exterior is visible in the background, showcasing a large parking area and covered terrace with a red roof, surrounded by greenery.
Villa in Portobelo
4.93 out of 5 average rating, 29 reviews

Villa con piscina y cancha de fútbol en Portobelo

Quiet and spacious private villa in Portobelo, Colón. Ideal for rest and enjoyment as a family or with friends. Surrounded by nature, it has a large garden, natural stream, soccer field, swimming pool with waterfall and slide, 2 furnished huts, barbecue area and terrace. It has 3 bedrooms, 3 bathrooms, living and dining room, TV, Starlink internet, A/C and equipped kitchen. It is recommended to bring inflatable mattresses with sheets for the extra guests. @casalunabv

Guest favorite
A serene swimming pool is depicted surrounded by lush palm trees, with the tranquil sea visible in the background. The water's clear blue tiles reflect the sky and nearby greenery, while the gentle curvature of the pool edge invites relaxation.
Villa in Portobelo
4.97 out of 5 average rating, 79 reviews

Entire Villa with pool in front of beach!

Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Guest favorite
The image shows a bright outdoor area featuring a clear blue swimming pool bordered by light stone paths and lush green grass. A tall palm tree provides shade in the foreground, while the backyard includes a single-story house and an open patio area under a roof.
Villa in Punta Chame
4.97 out of 5 average rating, 140 reviews

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Guest favorite
Villa in Juan Gallego
4.84 out of 5 average rating, 32 reviews

Beachfront Private Villa · 5BR · Direct Sea Access

Nestled as the prime choice for beachfront living near Panama City, this exclusive Villa boasts unparalleled views of the Caribbean Sea. With a private entrance to the sea and a verdant green area for relaxation or private barbecues, it offers the epitome of luxury for discerning guests seeking a nature-infused escape. Perfectly blending tranquility with top-tier amenities, it's an oasis for those craving the serenity of waterfront living.

Top guest favorite
The private outdoor pool is set against a backdrop of lush greenery and the home's elegant architecture. Comfortable seating arrangements are positioned nearby on the pool deck, inviting relaxation. Large windows reflect natural light, enhancing the spaciousness of the surrounding area.
Villa in Punta Paitilla
4.98 out of 5 average rating, 101 reviews

Beautiful House in Panama w/ King Beds + Pool

Beautiful home in Punta Paitilla with 6 bedrooms, 5.5 bathrooms and 8 beds, ideal for up to 16 guests. Enjoy a private pool, an on-site gym, and modern, comfortable spaces designed for families, groups, or business travelers. The layout offers privacy, style, and convenience. Located in one of Panama City’s most exclusive areas, just steps from shopping centers, restaurants, supermarkets, and the Cinta Costera.

Superhost
A plate is set with two fried eggs, positioned alongside crispy bacon and toasted bread. Fresh green onions and a sliced tomato add vibrant color. A glass of orange juice is visible in the background, enhancing the breakfast presentation.
Villa in Altos del Maria

Luxurious B&B house in Altos del Maria

No detail is overlooked at this charming and upscale place to stay. Certainly! When it comes to finding a luxury villa with spectacular views that offers both bed and breakfast, there are several options available. It would be helpful to know the specific location you have in mind so I can provide more accurate information. Could you please let me know the destination where you would like to find such a villa

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