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Places to stay near Buffalo Museum of Science

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Top-rated vacation rentals near Buffalo Museum of Science

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
An intricately crafted wooden staircase features a decorative rail with a stylized griffin design. A vibrant rug adds warmth to the entryway, where a round table holds a large vase of green flowers, complementing the rich wood paneling throughout the foyer.
Home in Elmwood Village

Massive Architecturally Amazing Grand Victorian

Architecturally Massive Amazing Victorian 7 bed/7 bath Grand 6000 sq. foot Queen Victorian Mansion, 7 bedrooms (9 beds - sleeps 16), 7 baths,(4 full 3 half) Heart of the Elmwood village. New kitchen with quartz countertops, remodeled baths, spectacular foyer, two sitting parlors, billiard room, new central air on 2nd and 3rd floors. two 50"smart t.v.s, period furnishings, Lots of natural light in modern bedrooms. meticulously restored, Ideal for large groups and weddings. Check out the pics!

4.93 out of 5 average rating, 154 reviews
Guest favorite
An inviting seating area is presented, featuring a gray loveseat adorned with butterfly-patterned cushions. Accompanying ottomans complement the seating arrangement. A stylish lamp stands beside the couch, and natural light filters through the windows adorned with blinds.
Apartment in Buffalo

Home away from home

Sunny Urban Retreat with two bedrooms Welcome to my delightful upstairs apartment. This sun-kissed haven offers, comfort & convenience. highlights: Two bedrooms rest easy in the spacious primary bedroom in a queen- size bed or choose the cozy second bedroom with a full-size bed. The kitchen features a stove, refrigerator and microwave. Location: situated just one mile from the medical corridor. Buffalo's vibrant theater district and Canalside are 3 miles away. Niagara Falls awaits 21 miles.

4.85 out of 5 average rating, 192 reviews
Top guest favorite
A spacious living area features a large sectional sofa positioned against a wall of wood paneling. Oversized windows allow natural light to fill the space, while a modern television is mounted adjacent to the seating area. A plush area rug adds comfort underfoot.
Loft in Downtown Buffalo

Sunlit Serenity on Pearl: 2-BR in Downtown Buffalo

Welcome to your private oasis on Pearl Street — where modern elegance meets effortless comfort. Bathed in natural light and upscale finishes, this refined 2BR offers a sophisticated stay. Situated in the heart of downtown, you're steps away from Buffalo’s best dining, nightlife, and entertainment. Enjoy walkable access to: Shea’s Theater, 500 Pearl, Town Ballroom, Electric City, Convention Center etc! - 5 mins to Sahlen Field (Bisons) & Keybank (Sabres) - 20 mins to Highmark Stadium (Bills)

4.96 out of 5 average rating, 113 reviews
Top guest favorite
A modern living space features a comfortable dark sofa adorned with a bright throw. A compact kitchen with sleek cabinetry and a black stove sits in the background. Natural light enters through large windows, highlighting the warm wooden flooring.
Apartment in Elmwood Village

Cozy Carriage House on Elmwood

Beautiful Airbnb inside a historic carriage house. Located directly on Elmwood Avenue but tucked back & secluded for a peaceful stay. Cozy interior with coffee bar included. The cottage’s prime location is within walking distance to many restaurants, bars, cafes, boutique shops, Delaware Park, the AKG and Birchfield Penney art museums, and more. Off-street parking allows easy access to adventure outside of the village with Niagara Falls & the Bills Stadium just a 20-30 min. drive/Uber away!

4.98 out of 5 average rating, 314 reviews
Top guest favorite
A spacious kitchen is highlighted by light blue walls and granite countertops. Wooden shelves display items on one side, while a breakfast nook with large windows invites natural light. Three wooden stools are positioned at the counter for casual seating.
Home in Elmwood Village

Spacious Historical Home by Parks, Shops, 4bd 2ba

Enjoy the unique charm of this 2,200 sq ft historic home. Gather in the light-filled, open living area featuring century-old woodwork, or cook together in the fully equipped kitchen. Upstairs, 4 roomy bedrooms comfortably sleep 8. Whether you need to catch up on remote work in the quiet office, unwind in the dedicated Zen room, or grill on the private patio, there’s space for everyone. Best of all, you’re just 7 minutes from downtown and 15 from the airport. Book your seamless stay today!

4.89 out of 5 average rating, 163 reviews
Guest favorite
A cozy studio is presented, featuring a sofa in vivid teal and a light-colored side table. A patterned rug spans the wooden floor. Partially visible is a bedroom with a spacious bed positioned behind a curtain, illuminated by soft interior lighting.
Apartment in Elmwood Village

Homey Private Penthouse

This cozy, centrally-located studio/1BR is in the heart of Allentown. It is 2 blocks from the new medical campus, five minutes from downtown, five minutes from Elmwood Village, and two minutes from all the bars of Allentown. It is across the street from many of the shops in Allentown. We are passionate about Buffalo and would love to host you and help make your Buffalo experience special. FYI, the unit can be noisy at night, especially on the weekend, and is on the third floor.

4.96 out of 5 average rating, 111 reviews
Guest favorite
A modern dining area features a round wooden table surrounded by four white chairs. A stylish light fixture hangs above, complemented by green accent walls. The open layout connects to a well-equipped kitchen with white cabinetry and bar seating, illuminated by natural light from surrounding windows.
Apartment in Elmwood Village

Five Points Apartment- Upper Unit

Updated Upper Unit Apartment. Great City Location! Walking Distance to Five Points, and Lower West Side Restaurants and Shops. Off Street Parking (when available). In Unit Laundry. WiFi. Pets Allowed ($50 pet fee). Queen Bed and Fold Down Futon. Blocks from D’Youville University and minutes from Buffalo State University! Close to Kleinhans Music Hall, Elmwood Village and Allentown! 10 Min Drive To KeyBank Center - 20 Min Drive To Highmark Stadium - 20 Min Drive To Niagara Falls

4.87 out of 5 average rating, 270 reviews
Top guest favorite
A comfortable living area features a dark leather sofa and armchair, complemented by a round coffee table. Natural light fills the space through large windows, while a dining table with black chairs is visible in the background beneath framed art.
Apartment in North Buffalo

Lovely 2-Bedroom Apartment in North Buffalo

Welcome to Buffalo, and our newly remodeled apartment. This upper 2-bedroom, 1-bathroom apartment has all new floors, kitchen, bedrooms, and bathroom (2021). One bedroom has a queen bed and the other bedroom has a single bed with a pull out single "trundle bed" underneath. All have new mattresses and linens (June 2021). The apartment is bright, spacious, and well equipped. Located on popular Hertel Avenue, there are many restaurants, bars and shops within walking distance.

4.93 out of 5 average rating, 250 reviews
Top guest favorite
A single-story cottage features a large, paved driveway leading to a maroon garage door. The exterior showcases a mix of stone and wood siding, accented by vibrant green shrubs and trees in the background under a clear blue sky.
Place to stay in Buffalo

Private 3-bedroom cottage at St. Patrick's Friary

Newly renovated private cottage on the historic grounds of Buffalo's first Irish Catholic church complex in the popular Larkinville area of Buffalo. Only a 7-minute drive from downtown/RiverWorks/Canalside, and 1 minute walk to Larkin Square, there are plenty of restaurants, breweries and attractions nearby. This cottage has a beautiful flower garden and fresh herbs you can pick and use while grilling on the patio. There is a washer and dryer in the garage.

4.95 out of 5 average rating, 279 reviews
Superhost
Natural light filters through large windows, illuminating a cozy living area. A soft brown couch is adorned with decorative pillows. A light wooden coffee table sits beneath a round, jade-colored bowl. A chair with a patterned cushion completes the space.
Apartment in Buffalo

Freshly Renovated 2 Bedroom

Fully stocked for long-term stays, this newly renovated upper apartment is the perfect spot to rest your head whether you're in town for work or play. Walking distance (.5 miles or less) to Westside Tilth Farm, Mister Sizzle's, BreadHive Bakery & Cafe, Foibles, Five Points Bakery, Butter Block, Remedy House, & more. 10 minutes to downtown Buffalo, 22 minutes to Highmark Stadium, 28 minute drive to Niagara Falls. We look forward to hosting you!

4.84 out of 5 average rating, 164 reviews
Top guest favorite
Cottage in Fort Erie

Steps to the Beach + Lakeviews + HotTub + Elevator

Unwind at this The Red Lakehouse just steps from the beach, featuring a private hot tub, fire pit, and covered balcony with Lake Erie views. Perfect for families, groups, and getaways, this professionally designed home offers 3 bedrooms with private ensuites for ultimate comfort and privacy. Minutes to Niagara Falls, Crystal Beach, and the USA border — yet tucked in a quiet, relaxing neighbourhood. A spotless, thoughtfully curated stay.

4.96 out of 5 average rating, 162 reviews
Superhost
The exterior of a grand white mansion is shown, featuring a light green metal roof and multiple gabled dormers. The well-maintained front yard includes a pathway leading to the entrance, with mature trees surrounding the property.
Home in Elmwood Village

Historic Mansion Built in 1896, Pan Am. Expo Era

Allow our home to be your home for your next visit to Buffalo. Summer Street Guest House was built for entertaining. This gracious old mansion is filled with warmth and love. Each room has its own glow. We occupy the third floor. The large living room, dinning room and kitchen on the first floor and four large bedrooms on the second floor are available for your enjoyment.

4.79 out of 5 average rating, 139 reviews

Popular amenities for vacation rentals near Buffalo Museum of Science

KitchenWifiPoolFree parking on premisesAir conditioning

Other top sights near Buffalo Museum of Science

Niagara Falls State Park

487 locals recommend

Niagara Falls

511 locals recommend

Casino Niagara

359 locals recommend

Canalside

283 locals recommend

Butterfly Conservatory

310 locals recommend

Loomis's Delevan Drive-In

6 locals recommend

Condo rentals with wifi

Top guest favorite
A spacious living area is highlighted by a large sectional sofa and a dining table surrounded by wooden chairs. A brick wall features a mounted television, while art adorns the walls. Soft lighting creates a comfortable and inviting space.
Condo in Buffalo

Quiet nice and clean apartment downtown Buffalo

4.93 out of 5 average rating, 259 reviews
Guest favorite
An aerial view showcases the vibrant fall foliage lining the banks of the river, with a bridge arching over the water. The city skyline rises in the background, partially obscured by mist, while the rushing water reflects glimpses of autumn colors.
Condo in Niagara Falls

Skyline Square Condo

4.93 out of 5 average rating, 149 reviews
Guest favorite
A welcoming living area features a comfortable brown sofa with blue accent pillows and a gray armchair. A small dining table is positioned alongside a decorative bulletin board. Natural light enters through a window adorned with light curtains, illuminating the contemporary decor.
Condo in Niagara Falls

The Eugene

4.91 out of 5 average rating, 561 reviews
Superhost
A spacious living area showcases a comfortable sofa and a coffee table. A modern kitchen is visible in the background, featuring new appliances and a bar-style seating arrangement with bright red stools. A large TV displays a scenic image, adding to the inviting atmosphere.
Condo in Niagara Falls

Entire Condo Minutes from Niagara Falls (USA)

4.79 out of 5 average rating, 687 reviews
Guest favorite
The kitchen area displays sleek gray cabinetry and stainless steel appliances, including a refrigerator, stove, and microwave. A coffee maker is positioned on the countertop beside a kettle. A small potted plant adds a touch of greenery to the space, complemented by a cozy leather couch.
Condo in Niagara Falls

Modern Niagara Falls Condo

4.85 out of 5 average rating, 302 reviews
Guest favorite
The open living area features a modern kitchen with a gray island and sleek appliances. A comfortable sofa faces a glass coffee table, while a round dining table accommodates four. Soft lighting enhances the clean and neutral decor, creating a functional and inviting space.
Condo in Niagara Falls

Cozy 2-Bedroom Condo with Parking in Niagara Falls

4.88 out of 5 average rating, 109 reviews
Guest favorite
Condo in Niagara Falls

Chic Contemporary 2 Bed| 5 Mins to the falls

4.88 out of 5 average rating, 160 reviews
Guest favorite
A well-equipped kitchen features white cabinetry and modern appliances, including a microwave and refrigerator. Barstools are positioned at the island. The open living space showcases a comfortable sofa facing a stone fireplace and a large window with natural light illuminating the area.
Condo in Elmwood Village

Elmwood 1 King 1 Queen 1.5 bath Garage EV Charger

4.94 out of 5 average rating, 35 reviews

Family-friendly house rentals

Top guest favorite
A bright and airy open-concept living space features a large dining table surrounded by blue chairs, positioned next to expansive windows that offer views of the lake and Buffalo skyline. A wall-mounted TV is visible, enhancing the modern, clean design.
Home in Fort Erie

Bright, Beautiful Lakefront @ Historical Fort Erie

4.95 out of 5 average rating, 177 reviews
Top guest favorite
Home in Buffalo

Oasis | Patio, Pool, NEW Putting Green, Fire Pit

4.96 out of 5 average rating, 142 reviews
Guest favorite
A well-maintained house is viewed from the side, showcasing a neatly trimmed lawn. A blooming tree adds a touch of color, while tall trees and a fence frame the property. The exterior features a combination of white and grey cladding under a metal roof, contributing to its character.
Home in North Buffalo

Beautiful Victorian House

4.82 out of 5 average rating, 199 reviews
Guest favorite
Home in Elmwood Village

The Italianate: Historic Home w/ Sauna and Firepit

4.9 out of 5 average rating, 194 reviews
Top guest favorite
A bright living room features large bay windows surrounded by elegant drapes. A comfortable sofa is complemented by an oversized leather ottoman, while a textured area rug adds warmth. Decorative wood accents enhance the architectural character, and a modern lamp provides additional lighting.
Home in North Buffalo

Architectural Urban Escape: Checking all the boxes

5.0 out of 5 average rating, 138 reviews
Top guest favorite
A spacious living area is highlighted by a green couch and two brown leather swivel chairs. A circular marble coffee table sits on a colorful area rug. The bright kitchen is visible in the background, featuring modern appliances and cabinetry.
Home in Williamsville

*Brand New Home in WNY!* - Sleeps 13!

5.0 out of 5 average rating, 108 reviews
Top guest favorite
A view through a set of wooden doors leads into a bright room featuring large abstract artwork in shades of blue and gray. The hardwood floor reflects the soft lighting, creating a welcoming entry into the space.
Home in Elmwood Village

Beautiful Home for Whole Family!

4.97 out of 5 average rating, 121 reviews
Top guest favorite
A classic downtown Buffalo double/duplex is featured, showcasing a brown brick facade and a sloped roof with overhanging eaves. The house is surrounded by well-maintained grass and trees. Two balconies with potted plants are visible, providing outdoor space above the ground level.
Home in Buffalo

Down town Buffalo, Entire house

4.96 out of 5 average rating, 257 reviews

Apartment rentals with air conditioning

Superhost
Apartment in Elmwood Village

Cozy & Walkable Elmwood Village Charmer

4.91 out of 5 average rating, 412 reviews
Guest favorite
A bright studio apartment features vaulted ceilings and an open layout. A plush queen bed is visible alongside a cozy seating area with a leather sofa. A fully equipped kitchen includes modern appliances, and a dining table is set for two. Natural light streams through the windows.
Apartment in Elmwood Village

Spacious Private Retreat with Kitchen

4.93 out of 5 average rating, 215 reviews
Guest favorite
The living area features a comfortable gray couch with decorative cushions, a wooden side table with a lamp, and an area rug. An artistic cityscape is displayed on the wall, while a dining area is visible through the archway with a table and chairs.
Apartment in Elmwood Village

Historic Apartment Steps Away from Allentown Area

4.84 out of 5 average rating, 332 reviews
Guest favorite
A vibrant red couch with colorful patterned cushions is positioned against a white wall. A small table stands beside it, featuring a lamp and a decorative vase with flowers. Light streams through two wooden-blinded windows, illuminating the wooden floor.
Apartment in Elmwood Village

Suite Studio ❤️️ (Free Parking, Elmwood Village!)

4.79 out of 5 average rating, 689 reviews
Top guest favorite
A stylish living area features a dark sectional sofa, a tufted ottoman, and a low table. Light from large windows illuminates the space, showcasing framed artwork on the wall. A dining table with pink chairs is set in the background, adding a modern touch.
Apartment in Elmwood Village

Aroma BnB-Lovely 1 Bdrm.+

4.95 out of 5 average rating, 185 reviews
Top guest favorite
An open living and dining area is displayed, featuring a light wood dining table surrounded by white chairs. A cozy seating arrangement is visible in the background, with a large window allowing natural light to fill the space, highlighting the modern decor.
Apartment in North Buffalo

Spacious 3 Bed Delaware Art Park Apartment

4.99 out of 5 average rating, 179 reviews
Top guest favorite
The living room features large windows allowing natural light to fill the space. A dark sofa is adorned with brightly colored pillows, accompanied by an armchair and a coffee table. A patterned area rug anchors the room, with artistic accents enhancing the decor.
Apartment in North Buffalo

Charming Upper in Lively Entertainment District

4.97 out of 5 average rating, 278 reviews
Top guest favorite
A dining area showcases a large white table surrounded by four light-colored chairs, set on a patterned area rug. A blue cabinet houses decorative items and plants, with a framed painting on the wall. Natural light filters through sheer curtains.
Apartment in Buffalo

Inspiring Oasis · Walkable heart of City •AC

4.92 out of 5 average rating, 156 reviews

Other great vacation rentals near Buffalo Museum of Science

Superhost
The kitchen features a combination of white cabinetry and dark countertops, accented by a checkered black and white floor. Large windows allow natural light to fill the space, while a decorative curtain offers privacy. Essential appliances, including a stove and dishwasher, are included.
Apartment in Elmwood Village

Private 3 Bedroom Apartment with Porch

4.82 out of 5 average rating, 320 reviews
Top guest favorite
A modern kitchen features sleek white cabinetry and a dark countertop. A stainless steel refrigerator and gas stove are visible, alongside a microwave. Natural light enters through nearby windows, illuminating the space. A patterned rug lies on the floor, adding a touch of comfort.
Guesthouse in North Buffalo

Hidden Parkside Carriage House near everything.

4.99 out of 5 average rating, 256 reviews
Top guest favorite
The living room features a cozy arrangement of light-colored sofas with colorful accent pillows. A dark coffee table is centered in the space, complemented by a patterned rug beneath. A brick fireplace serves as a focal point, with built-in shelves displaying books and decor, while natural light filters through the windows.
Apartment in Elmwood Village

Elegant Elmwood Village Hideaway-New Outdoor Patio

4.96 out of 5 average rating, 182 reviews
Top guest favorite
The exterior of the home features a brick facade with white siding on the upper level. A welcoming front entrance is framed by a set of steps leading to a brown door. Lush greenery and well-maintained shrubs surround the entryway, creating a serene atmosphere.
Apartment in Buffalo

Charming Neighborhood Retreat

4.95 out of 5 average rating, 638 reviews
Guest favorite
A cozy sleeping area features a queen-size bed with a decorative headboard, dressed in a light grey quilt. Bright orange accent pillows add a pop of color. Two bedside lamps flank the bed, and natural light filters through the window covered with light curtains.
Apartment in Buffalo

New Cozy Getaway, Minutes from Downtown

4.95 out of 5 average rating, 104 reviews
Guest favorite
The exterior of a historic castle-style residence showcases intricate stone and brick detailing, complemented by lush greenery. A charming turret with a conical roof is visible, along with a balcony overlooking the garden. Sunlight filters through scattered clouds, enhancing the serene atmosphere.
Home in Elmwood Village

A Castle in the Heart of Buffalo

4.91 out of 5 average rating, 58 reviews
Guest favorite
An inviting outdoor space features a sparkling heated pool surrounded by lush green grass and mature trees. A charming farmhouse is visible in the background, with a spacious deck equipped with seating areas and a shaded umbrella. The area exudes a tranquil, natural setting.
Cottage in Fort Erie

Lakefront Getaway w/ Private Nordic Spa + Hot tub

4.91 out of 5 average rating, 97 reviews
Top guest favorite
Home in Cheektowaga

Family-friendly|Game Room| Sauna|Laundry|Karaoke

5.0 out of 5 average rating, 22 reviews