
House vacation rentals in Brandywine
Find and book unique houses on Airbnb
Quick stats about house rentals in Brandywine

Total vacation rentals
Explore 20 vacation rentals in Brandywine

Nightly prices starting at
Brandywine vacation rentals start at ﺩ.ﺇ 184 per night before taxes and fees

Verified guest reviews
Over 220 verified reviews to help you choose

Wi-Fi availability
20 of Brandywine vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Brandywine rentals

4.7 Average rating
Brandywine stays receive an average rating of 4.7 out of 5 from guests
Top-rated house rentals in Brandywine
Guests agree: these houses are highly rated for location, cleanliness, and more.

*Brand New | Modern | Lux 4 BR | Huge | 24 m to DC
Dee's Lounge will offer you the ULTIMATE perfect stay! Indulge in a luxurious and refined experience that is sure to leave you feeling refreshed, relaxed, and rejuvenated! This space is designed to make you feel like you've escaped your everyday life. Whether it's a girl trip, family time or hanging with your friends, you are sure to have an amazing time! We are readily available to accommodate your needs and make sure that you enjoy your time here! UPDATE 7/17 Grass room is under construction
4.91 out of 5 average rating, 157 reviews
Beautiful and spacious 3 bedroom
Beautifully decorated and spacious home in a charming, Alexandria neighborhood near the King Street metro and the shops and restaurants of Old Town. Just a 16 minute drive to downtown Washington DC, with a chef's kitchen and a relaxing great room. The house is also just a 10 minute drive to the new MGM Casino or the Gaylord Resort and Convention Center at National Harbor. The "no parties in house" rule is strictly followed. If you want to have a party or an event, this is not the place for you.
4.97 out of 5 average rating, 1116 reviews
Fabulous Private Potomac Waterfront Retreat
Fabulous private Potomac WATERFRONT retreat, 2+acres, stylish, 4 bd/4 ba. Winter work/vacation: 40% discount for monthly rental. 45 min to DC. Park-and-ride commuter bus 9 m away. Verizon FIOS gigabit wifi. Modern style décor. Guest House for in-laws/nanny; 4 kayaks & river deck for fishing/cocktails; 65” Smart TV; large deck w/ grill. 3-car garage; fireplace, gorgeous sunsets. ACCESSIBLE: ALL 1 level, 20 ft ramp from garage. No smoking, no pets, no events or parties. Children welcome.
4.94 out of 5 average rating, 101 reviews
Iconic Chesapeake. Unparalleled Luxury.
Autumn at The Cottage at Silver Water is peaceful, cozy, and a little magical. Crisp days invite you to kayak, explore the shoreline, or enjoy the changing colors. Evenings bring golden skies, spectacular sunsets, cool breezes, and fires by the water. Inside, the cottage is warm and inviting, with luxurious bedding, curated art, and thoughtful amenities for a relaxed, memorable stay. Come experience autumn at Silver Water—and see why every guest has given their stay five stars.
5.0 out of 5 average rating, 217 reviews
Cozy Retreat National Harbor and DC Pet|Backyard
Welcome to this calm, stylish, cozy, private space where you can relax and enjoy your special moments. 20 min away from the Capitol Downtown DC, 10 minutes away from MGM and National Harbor and 5 minutes away from Andrew Airforce Base. Free parking and amenities competing a luxury hotel. Split level, 2 bedroom, 2 bathroom townhouse with a large backyard, patio, build in out door grill. Lots of free parking. Your pets are welcome. Allow me to enhance your experience.
4.84 out of 5 average rating, 260 reviews
5-BR Home near DC Metro -Free Parking/Full Kitchen
RARE FIND — Main-Level Bedroom & Bath with No Steps! Welcome to your stylish D.C. retreat! This fully renovated 5-bedroom, 4-bathroom home offers 3,500 sq ft of open-concept living, just 3 minutes from the Metro and 10 minutes from the White House. Enjoy free street parking. Perfect for families or business travelers with a main-floor bedroom, chef’s kitchen, double living rooms, fast Wi-Fi, and smart TVs. Book your stay today and experience D.C. in comfort and style.
4.97 out of 5 average rating, 337 reviews
SPACIOUS Single Home near DC & National Harbor
Welcome this spacious single-family home relaxing by the waterfront for your getaway. It is perfect for vacations, retreats, meetings, and BUSINESS travelers. Create memories , beautiful experiences while enjoying a STUNNING lovely 6 bedrooms & 5 full Bath home with landscape garden, LUXURY settings, large custom kitchen, and EXQUISITE main suite ,close to Washington, National Harbor, MGM casino, Alexandria, and Tanger outlets. Provide one roll paper towel per stay
4.9 out of 5 average rating, 175 reviews
Private Pool | Modern | Lux 4 BR Retreat | Near DC
Relax with the whole family at this peaceful estate. Newly Remodeled Modern Farmhouse. Enjoy a stylish master bedroom with a double shower and deep freestanding soaker tub. Plenty of areas to relax in and watch movies or enjoy the beauty of the 100-foot-tall trees on the spacious 2-acre lot. Have fun with the Queen-sized bunk beds or if you have a little work to do you can use the home office complete with docking station, web cam and double large screen monitors.
4.84 out of 5 average rating, 122 reviews
Beautiful & Serene |Spacious Home w/ Ensuite Baths
Beautiful & Serene is a spacious 5-bedroom, 6-bath home near Washington, D.C., offering a calm, functional place to settle in comfortably. Each bedroom includes a private bath, balancing personal space with shared living areas. Open common spaces, reliable high-speed Wi-Fi, and dedicated work zones support extended stays and remote work. Furnishings are chosen for comfort and everyday use, making the home well-suited for families and longer visits.
4.94 out of 5 average rating, 106 reviews
Luxurious | Spacious | Hot Tub | Close To D.C
Indulge in the luxury and charm of this spacious colonial-style retreat in Fort Washington, Maryland. With 6 bedrooms and 3 bathrooms, this home is the perfect choice for families, large groups, friends, couple getaways or anyone seeking comfort and convenience just minutes from Washington, D.C. Enjoy modern amenities, a hot tub, a stunning backyard, and plenty of space to relax, recharge, and create lasting memories. Suitable for 12 Guests.
4.91 out of 5 average rating, 111 reviews
Waterfront Sanctuary only 50 Min. From DC/Balt.
New full home renovation with gourmet kitchen, wide open floor plan, multiple guests rooms, and a bunk room that accommodates 12. An inviting space that welcomes any couple or a large extended family. This home sits with only three other homes on a private peninsula and has water access on both sides. It is conveniently located less than an hour from DC and Baltimore on the west coast of the Bay (no need to cross the Bay Bridge).
4.97 out of 5 average rating, 112 reviews
Modern 6BR • Close to DC & Annapolis
Bright and spacious 6 bedroom, 5.5 bathroom home with a gym and sauna in a quiet, safe Largo neighborhood. Perfect for families and relaxed groups. Woodmore Town Center is under 5 minutes for groceries, dining, and shopping. About 20 minutes to DC and Silver Spring, with the Largo Town Metro only 7 minutes away for easy access to all major lines. Fast Wi-Fi, comfy beds, friendly neighbors, and plenty of space to unwind.
4.82 out of 5 average rating, 178 reviewsPopular amenities for Brandywine house rentals
House rentals with a pool

Historic Rousby Hall, Waterfront, Pool, Beach
4.99 out of 5 average rating, 178 reviews
5BD nr Nat’l Harbor, MD, DC & VA w/yard Oasis
4.92 out of 5 average rating, 103 reviews
The Little Gypsy BoHome
4.99 out of 5 average rating, 255 reviews
Large Home w/ Pool, Gym, 7 Bedrooms, Sleeps 21
4.86 out of 5 average rating, 227 reviews
Chesapeake Bay Beach House with Pool and Hot Tub
4.98 out of 5 average rating, 101 reviews
Stunning Riverfront Home w/ Pool, Hot Tub & Kayaks
4.91 out of 5 average rating, 124 reviews
Nature Zen *Metro Walk *Visit DC *Relaxing Lakes
4.91 out of 5 average rating, 143 reviews
*NEW* Huge 5Br Entertainment Retreat, Near DC
4.92 out of 5 average rating, 61 reviewsWeekly house rentals

The River House, a Wicomico Beach Retreat
4.91 out of 5 average rating, 129 reviews
Historic Apothecary | 2 Master Suites | Old Town
4.96 out of 5 average rating, 177 reviews
8 Acre Waterfront Oasis! Pets are Free! 140ft Pier
4.98 out of 5 average rating, 154 reviews
Blue Pearl-Luxury estate with private dock/jacuzzi
4.97 out of 5 average rating, 107 reviews
Beautiful Home Away From Home
4.91 out of 5 average rating, 111 reviews
@National Harbor Retreat |Mins to MGM&Gaylord&DC.
4.95 out of 5 average rating, 141 reviews
Fresh Air & Modern Farm Charm
4.5 out of 5 average rating, 4 reviews
The Royal Estate
5.0 out of 5 average rating, 38 reviewsPrivate house rentals

Spacious 5BR w/parking near DC Sleeps 12
5.0 out of 5 average rating, 9 reviews
Spacious Retreat Near DC| Free Parking + Sleeps 8
4.82 out of 5 average rating, 28 reviews
Home in Fort Washington| DMV
4.94 out of 5 average rating, 48 reviews
6BR Retreat, Game Rm, Fire Pit, Gym, near DC & MGM
5.0 out of 5 average rating, 31 reviews
Home in National Harbor Area w/ Deck + Fire Pit!
4.91 out of 5 average rating, 45 reviews
Private 2BR Apt Suite | 30 Min to DC & Natl Harbor
4.8 out of 5 average rating, 10 reviews
Spacious 5BR Retreat Near Nat'l Harbor, MGM & D.C.
5.0 out of 5 average rating, 20 reviews
Luxury 5 Bedroom 3 Bathroom home
4.87 out of 5 average rating, 52 reviewsDestinations to explore
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