
Vacation rentals in Brandywine
Find and book unique accommodations on Airbnb
Quick stats about vacation rentals in Brandywine

Total vacation rentals
Explore 40 vacation rentals in Brandywine

Nightly prices starting at
Brandywine vacation rentals start at ﺩ.ﺇ 184 per night before taxes and fees

Verified guest reviews
Over 310 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
40 of Brandywine vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Brandywine rentals

4.8 Average rating
Brandywine stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated vacation rentals in Brandywine
Guests agree: these stays are highly rated for location, cleanliness, and more.

*Brand New | Modern | Lux 4 BR | Huge | 24 m to DC
Dee's Lounge will offer you the ULTIMATE perfect stay! Indulge in a luxurious and refined experience that is sure to leave you feeling refreshed, relaxed, and rejuvenated! This space is designed to make you feel like you've escaped your everyday life. Whether it's a girl trip, family time or hanging with your friends, you are sure to have an amazing time! We are readily available to accommodate your needs and make sure that you enjoy your time here! UPDATE 7/17 Grass room is under construction

Cheerful1 bedroom basement with separate entrance
Take it easy at this unique and tranquil getaway. Keeping it simple and clean at this peaceful and centrally-located place. Cozy and placed in a beautiful quiet neighborhood. one bedroom Suite with its own bathroom and private side entrance provides a relaxing atmosphere for work or vacation. No shared spaces. No keys needed . it's a keyless secure entrance. There is no kitchen, however, the Suite includes fridge, microwave, keurig coffee machine with included coffee pods, cups and air fryer.

Historic Apothecary | 2 Master Suites | Old Town
Majestic, pre-Civil War Italianate brick home in favored southeast Old Town. Steps away from King Street and 2 blocks to the waterfront, location is unbeatable! This 3-story home established in the 1800s served as a former apothecary. New renovations offer utmost luxury, distinctive architecture with genuine hospitality and true sense of history and charm. 2 Masters Suites 4K 65in TVs w/ Streaming Hi-Speed Internet Dedicated Workspace 24 hr Self Check-in Washer/Dryer Free parking upon request

Eagles Nest: Studio Apartment, Maryland
Serenity! Studio apartment—peaceful, natural scenery near Washington D.C., 2 hospitals, 2 wineries, multiple restaurants, horse-back riding, biking trails, fishing, Dr. Mudd’s historic house, All American Harley Davisson, Budds Creek, Maryland International Raceway, & 4 Military Bases:. During downtime, relax with 2 TVs, Wi-fi, a mini kitchen (Keurig, fridge, microwave, & cabinets with dishes for 4 people). Enjoy the private washer/dryer, full bath, dining table, work desk & walk-in closet.

The Parker House
Whether your taking a family vacation to the DC area or traveling for business. Avoid the crowds of the city and join us here in the peaceful suburbs of Upper Marlboro, MD. Easy access to the White House, Show Place Arena, National Museums, Smithsonian Zoo, The National Harbor and much more around the DMV area. Enjoy fun outdoors with 2 acres to run and play or with indoor games aplenty. Have a BBQ on the patio or relax by the firepit, let us help you relax and enjoy your stay!

Urban Cottage, MD minutes from DC/National Harbor
Come and enjoy our spacious detached cottage,lounge on your private back deck overlooking private parkland forests. A real urban escape in an excellent location! Just a few blocks away from the MGM Resort / Casino, National Harbor, and shopping. Across the river from historic Alexandria and 10-minutes from Washington,DC. Great for a solo adventure,couples,and friends (up to 4 guests). Enjoy the seasonal steam house and personal wood-burning stove if you book in the cold months.

*Brand New | Modern Farmhouse | Lux 4 BR | Near DC
Relax with the whole family at this peaceful estate. Newly Remodeled Modern Farmhouse. Enjoy a stylish master bedroom with a double shower and deep freestanding soaker tub. Plenty of areas to relax in and watch movies or enjoy the beauty of the 100-foot-tall trees on the spacious 2-acre lot. Have fun with the Queen-sized bunk beds or if you have a little work to do you can use the home office complete with docking station, web cam and double large screen monitors.

The Guest of Honor: Fenced Smart Home w/Hot Tub
This stylish ground-level only private space (Not a basement) is only 23 min from DC (30-35 min to downtown DC) 5 min from Andrew's Airforce Base, 15 min from the National Harbor & walking distance to Cosca Park. Cosca Park Amenities Include Baseball Fields, Outdoor Tennis Courts, Tennis Bubble, Walking Trail/Nature Trail, RestRooms, Playground, Skateboard Park, Paddle Boats on the Lake, Picnic Tables & Shelters, Nature Center, RV/Campground & parking lots.

Quiet cottage in the woods. King-bed suite.
Take it easy at this unique and tranquil getaway. Open floor plan with all the modern conveniences. King size bed, with space for an additional queen size air mattress. Washer, dryer, shower/bathtub. Note, there is no smoking or vaping allowed inside the Cottage, and absolutely no "4/20" products allowed on the property. Two night minimum for all reservations, and due to documented medical allergy concerns we are unable to host pets/animals of any kind.

Home Sweet Home! 3 bds | Bath | Kitch | Laundry
Stay and Relax with the whole family in this brand new spacious basement apartment with lots of room for fun. Easy access to the White House, Six Flags, Chesapeake Beach, National Museums, Smithsonian Zoo, and a host of other beautiful sights in the D.C., Maryland, and Virginia (DMV) areas. The nightly rate includes up to two guests, and there is a $20 per night charge for each additional guest staying overnight in the unit.

Weems Creek Cottage, Annapolis Waterfront
(August, 2025) Jim is the best host we’ve ever had. Super responsive, reached out to let us know the place was ready and we could check in early. The house is perfect size for 2 adults and a kid. Beautiful view and really comfortable. We loved the screened in porch. We walked to breakfast at the smoothie place and had a great walk down to the naval academy. We would definitely stay here again.

Luxury Farm Cottage on 40 Acres Private Estate
Welcome to your private countryside escape just minutes from Washington, DC. Nestled on a stunning 40-acre working farm, this cozy yet refined cottage offers the perfect blend of luxury, privacy, and natural beauty. Whether you’re looking for a peaceful weekend getaway, romantic retreat, creative escape, or nature reset, this space gives you room to breathe, unwind, and reconnect.
Popular amenities for Brandywine vacation rentals
Stay near Brandywine's top sights
Other great vacation rentals in Brandywine

Private full basement in a single family home

Beautiful countryside retreat within reach of DC

Modern, 2BR Single Fam, Renovated, Close to DC

Modern 4-Story Townhome Retreat Minutes From DC

Newly remodeled efficiency apartment.

Relaxing retreat on the river.

Adorable Large Efficiency Getaway Retreat

*NEW* Huge 5Br Entertainment Retreat, Near DC
Frequently Asked Questions
Are there family-friendly vacation rentals in Brandywine?
Brandywine has more than 10 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.
How much does it cost to stay in house rentals in Brandywine?
Experience the best of Brandywine with our house rentals, starting at about $50 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Are there pet-friendly vacation rentals in Brandywine?
Four-legged friends are welcome in Brandywine. Choose from more than 10 vacation rentals for guests traveling with pets.
Are there vacation rentals with a dedicated workspace in Brandywine?
Yes! Work meets play with ease at over 10 vacation rentals in Brandywine featuring dedicated workspaces. Stay connected and productive in your home away from home.
Do house rentals in Brandywine have air conditioning?
Absolutely! We offer over 20 house rentals with air conditioning in Brandywine. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Brandywine have a kitchen?
Absolutely! We offer over 20 house rentals with a kitchen in Brandywine. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Brandywine have wifi?
Absolutely! We offer over 20 house rentals with wifi in Brandywine. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Brandywine have free parking?
Absolutely! We offer over 10 house rentals with free parking in Brandywine. Enjoy a tailored experience with all the comforts you desire.
Destinations to explore
- New York Vacation rentals
- Philadelphia Vacation rentals
- Washington Vacation rentals
- Ocean City Vacation rentals
- Pittsburgh Vacation rentals
- Virginia Beach Vacation rentals
- Raleigh Vacation rentals
- Jersey City Vacation rentals
- Newark Vacation rentals
- Baltimore Vacation rentals
- Richmond Vacation rentals
- Atlantic City Vacation rentals
- Georgetown University
- M&T Bank Stadium
- National Mall
- The White House
- Nationals Park
- Walter E Washington Convention Center
- Baltimore Convention Center
- FedExField
- Oriole Park at Camden Yards
- Federal Hill Park
- Stone Tower Winery
- Johns Hopkins University
- National Museum of African American History and Culture
- Washington Monument
- Georgetown Waterfront Park
- The Anthem
- Capital One Arena
- CFG Bank Arena
- National Harbor
- Jiffy Lube Live
- Smithsonian National Zoological Park
- Merriweather Post Pavilion
- Howard University
- Patterson Park





