Vacation rentals in Brandywine

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Top-rated vacation rentals in Brandywine

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Home in Fort Washington
4.98 out of 5 average rating, 100 reviews

Haiku River House | 5BR Zen Retreat Near DC

Tranquil Japanese-style riverfront retreat 18min to Downtown DC. Watch boats glide by, relax with games, or explore National Harbor & MGM Casino. Serene 5BR/4BA home, peaceful retreat with open floor plan, 3 private wings, Peloton, and accessible baths. Enjoy smart TVs in every room, 50" HDTV, zen-like workspace, and fully stocked kitchen. Sleeps 10: K, Q x 4 Stunning sunsets on Potomac Chef's kitchen Designer mattresses Golden Tee arcade Workspace w/ FAST Wi-Fi Single-level home Park 4 cars

Top guest favorite
The exterior of a historic Italianate brick home features a light-colored facade with large windows. Adjacent, the interior showcases a stylish living area with a chandelier above a seating arrangement. A bright dining area is set for a meal, highlighted by large windows and elegant decor.
Home in Old Town
4.96 out of 5 average rating, 165 reviews

Historic Apothecary | 2 Master Suites | Old Town

Majestic, pre-Civil War Italianate brick home in favored southeast Old Town. Steps away from King Street and 2 blocks to the waterfront, location is unbeatable! This 3-story home established in the 1800s served as a former apothecary. New renovations offer utmost luxury, distinctive architecture with genuine hospitality and true sense of history and charm. 2 Masters Suites 4K 65in TVs w/ Streaming Hi-Speed Internet Dedicated Workspace 24 hr Self Check-in Washer/Dryer Free parking upon request

Guest favorite
An open concept living area features a combination of seating, including two armchairs and a side table. A dining area with a striking blue rug and wooden chairs is visible in the background, alongside a well-lit kitchen area with modern appliances.
Guesthouse in Owings
4.92 out of 5 average rating, 131 reviews

Patuxent River View

🏡Stay at this peaceful, amenity‑rich guest house near North Beach, Chesapeake Beach, and Herrington Harbour, with quick access to Washington, DC, Baltimore, and Annapolis. Enjoy a fully stocked kitchen, coffee, fast WiFi, a seasonal pool, and a shaded gazebo designed for comfort and convenience. Perfect for wedding weekends, family visits, work trips, and quiet coastal getaways, this cozy home base makes it easy to relax, cook, stream, and recharge between festivities and exploring the area.

Top guest favorite
A cozy sitting area features a comfortable blue sofa adorned with cushions. Large glass doors provide access to the outdoor space, complemented by colorful curtains. A small dining table and chairs are visible outside, framed by a patterned area rug on the wooden floor.
Guest suite in La Plata
4.89 out of 5 average rating, 302 reviews

Beautiful Rural Suite near Washington, D.C.

Enjoy a rural environment only 50 minutes outside of Washington, D.C., and 45 minutes away from Andrew's Air Force Base. Located in a quiet wooded neighborhood with horses, goats, ducks, and more this property allows children space to run and play. Stores are less than 10 minutes down the road. This is a perfect little haven, fully equipped with a kitchen and laundry facilities. Parking is available for boats and trailers. Please Note: Sunday check-in is at 4pm, unless requested otherwise.

Top guest favorite
Farm stay in Brandywine
4.91 out of 5 average rating, 11 reviews

Convenient Cozy Farm Cottage 15 Miles from DC

Welcome to your tranquil escape at our luxurious Farm Cottage nestled within a serene 40-acre private estate where everything you need is within easy reach. Located just a stone's throw away from Rte 301, shopping, culinary, and convenience meets comfort in this idyllic countryside setting. Offering a seamless blend of modern amenities and rustic charm, the cottage boasts a cozy ambiance with tastefully appointed interiors, providing a welcoming atmosphere for relaxation and rejuvenation.

Guest favorite
An elegant two-story home is set amidst lush greenery. The façade features a combination of stone and stucco with large windows, providing ample natural light. A welcoming front porch with rocking chairs invites relaxation, while flower beds add a touch of color to the landscape.
Guest suite in Upper Marlboro
4.9 out of 5 average rating, 29 reviews

The Parker House

Whether your taking a family vacation to the DC area or traveling for business. Avoid the crowds of the city and join us here in the peaceful suburbs of Upper Marlboro, MD. Easy access to the White House, Show Place Arena, National Museums, Smithsonian Zoo, The National Harbor and much more around the DMV area. Enjoy fun outdoors with 2 acres to run and play or with indoor games aplenty. Have a BBQ on the patio or relax by the firepit, let us help you relax and enjoy your stay!

Superhost
The interior of the cottage features a vaulted wooden ceiling with beams, creating an open atmosphere. A spacious sectional sofa faces a wood-burning stove. The kitchen is equipped with modern appliances, while light streams through large windows draped in sheer curtains.
Guesthouse in National Harbor
4.92 out of 5 average rating, 772 reviews

Urban Cottage, MD minutes from DC/National Harbor

Come and enjoy our spacious detached cottage,lounge on your private back deck overlooking private parkland forests. A real urban escape in an excellent location! Just a few blocks away from the MGM Resort / Casino, National Harbor, and shopping. Across the river from historic Alexandria and 10-minutes from Washington,DC. Great for a solo adventure,couples,and friends (up to 4 guests). Enjoy the seasonal steam house and personal wood-burning stove if you book in the cold months.

Guest favorite
Home in Waldorf
4.86 out of 5 average rating, 101 reviews

*Brand New | Modern Farmhouse | Lux 4 BR | Near DC

Relax with the whole family at this peaceful estate. Newly Remodeled Modern Farmhouse. Enjoy a stylish master bedroom with a double shower and deep freestanding soaker tub. Plenty of areas to relax in and watch movies or enjoy the beauty of the 100-foot-tall trees on the spacious 2-acre lot. Have fun with the Queen-sized bunk beds or if you have a little work to do you can use the home office complete with docking station, web cam and double large screen monitors.

Top guest favorite
Guesthouse in Brandywine
5 out of 5 average rating, 61 reviews

Quiet cottage in the woods. King-bed suite.

Take it easy at this unique and tranquil getaway. Open floor plan with all the modern conveniences. King size bed, with space for an additional queen size air mattress. Washer, dryer, shower/bathtub. Note, there is no smoking or vaping allowed inside the Cottage, and absolutely no "4/20" products allowed on the property. Two night minimum for all reservations, and due to documented medical allergy concerns we are unable to host pets/animals of any kind.

Guest favorite
A stylish bar area is showcased with a pool table in the foreground and a sleek bar counter adorned with emerald green stools. Pendant lighting hangs from the ceiling, providing modern illumination, while a television is mounted on the wall for entertainment.
Home in Waldorf
4.91 out of 5 average rating, 153 reviews

*Brand New | Modern | Lux 4 BR | Huge | 24 m to DC

Dee's Lounge will offer you the ULTIMATE perfect stay! Indulge in a luxurious and refined experience that is sure to leave you feeling refreshed, relaxed, and rejuvenated! This space is designed to make you feel like you've escaped your everyday life. Whether it's a girl trip, family time or hanging with your friends, you are sure to have an amazing time! We are readily available to accommodate your needs and make sure that you enjoy your time here!

Top guest favorite
Home in Fort Washington
5 out of 5 average rating, 32 reviews

Modern, 2BR Single Fam, Renovated, Close to DC

Relax and recharge in this fully renovated, one-level 2-bedroom, 1-bathroom single family home on over an acre located just minutes from Washington, D.C. Perfect for couples, small families, business professionals, students, remote workers or long-term travelers, this property is designed for both comfort and convenience. With bright open-plan living and modern amenities, it’s your ideal Capitol Family Home for up to 4 guests.

Top guest favorite
A spacious living room features a large sectional sofa, adorned with decorative pillows in neutral tones. A dark coffee table sits in front, and the soft carpet adds warmth to the area. Two doorways lead to adjacent rooms, offering convenient access.
Guest suite in Prince George's County
4.97 out of 5 average rating, 107 reviews

Home Sweet Home! 3 bds | Bath | Kitch | Laundry

Stay and Relax with the whole family in this brand new spacious basement apartment with lots of room for fun. Easy access to the White House, Six Flags, Chesapeake Beach, National Museums, Smithsonian Zoo, and a host of other beautiful sights in the D.C., Maryland, and Virginia (DMV) areas. The nightly rate includes up to two guests, and there is a $20 per night charge for each additional guest staying overnight in the unit.

Popular amenities for Brandywine vacation rentals

Frequently Asked Questions

  • Are there family-friendly vacation rentals in Brandywine?

    Brandywine has more than 10 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • How much does it cost to stay in house rentals in Brandywine?

    Experience the best of Brandywine with our house rentals, starting at about $50 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there pet-friendly vacation rentals in Brandywine?

    Four-legged friends are welcome in Brandywine. Choose from more than 10 vacation rentals for guests traveling with pets.

  • Are there vacation rentals with a dedicated workspace in Brandywine?

    Yes! Work meets play with ease at over 10 vacation rentals in Brandywine featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Do house rentals in Brandywine have air conditioning?

    Absolutely! We offer over 20 house rentals with air conditioning in Brandywine. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in Brandywine have a kitchen?

    Absolutely! We offer over 20 house rentals with a kitchen in Brandywine. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in Brandywine have wifi?

    Absolutely! We offer over 20 house rentals with wifi in Brandywine. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in Brandywine have free parking?

    Absolutely! We offer over 20 house rentals with free parking in Brandywine. Enjoy a tailored experience with all the comforts you desire.

Quick stats about vacation rentals in Brandywine

  • Total vacation rentals

    Explore 30 vacation rentals in Brandywine

  • Nightly prices starting at

    Brandywine vacation rentals start at ﺩ.ﺇ 184 per night before taxes and fees

  • Verified guest reviews

    Over 280 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    30 of Brandywine vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Brandywine rentals

  • 4.8 Average rating

    Brandywine stays are highly rated by guests—averaging 4.8 out of 5!

  1. Airbnb
  2. United States
  3. Maryland
  4. Prince George's County
  5. Brandywine