Places to stay near Arizona-Sonora Desert Museum

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Top-rated vacation rentals near Arizona-Sonora Desert Museum

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Top guest favorite

A spacious sleeping area features a plush bed with decorative pillows, complemented by large floor-to-ceiling sliding glass doors that open to a lush backyard. A black-bottom pool is visible just outside, surrounded by manicured greenery, creating a serene oasis.

Guesthouse in Tucson

4.96 out of 5 average rating, 394 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in an infrared or hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies—lounge in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top guest favorite

A spacious studio features a queen-sized bed adorned with a soft coverlet. A curved red lounge chair complements the warm adobe walls and wooden ceiling beams. Natural light filters through large windows, illuminating the cozy corner with a beehive fireplace, enhancing the tranquil atmosphere.

Guesthouse in Tucson

4.96 out of 5 average rating, 856 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (1-19-2024) "59 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the Eucalyptus Suite Airbnb and the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Guest favorite

A spacious cabin interior showcases a log bed with a custom headboard and warm, earthy tones. A rustic wooden dresser is positioned beside a charming lamp, while a large artwork of horses adorns the wall. Exposed beams and a textured ceiling create a cozy atmosphere.

Cabin in Tucson

4.95 out of 5 average rating, 456 reviews

Huge Swimming Pool with a Cozy Cabin to Stay In!

Peaceful, quiet nature retreat just outside the city. Chill out in the huge pool* (only shared with main house) & relax in a remodeled frontier cabin with hiking & mountain biking right out the front door, 5 mins to stores & restaurants. Only 15 min drive to downtown & the UA. Plenty of wildlife! It’s a perfect spot to unwind after a day in town, or get some time away to paint, write or reconvene with yourself, nature, or the one you love. (* NO HOT TUB has never worked & will NOT be working).

Guest favorite

The entrance to Sanctuary Cove is marked by a rustic stone wall and gate, surrounded by desert vegetation. The scenic backdrop features rolling hills and prominent rock formations under a clear blue sky, setting the tone for a secluded getaway.

Tiny home in Tucson

4.98 out of 5 average rating, 161 reviews

The Cottage @ Sanctuary Cove, 80 acres of serenity

A secluded getaway, Sanctuary Cove's Guest Cottage is surrounded by 80 acres of pristine Southwest Desert. Stewarded by a religious non-profit, Sanctuary Cove is a place of respite from the happenings of modern life. The property has hiking trails, easy access to less explored areas of Saguaro National Park, a non-denominational chapel for prayer and meditation, an amphitheater overlooking the Tucson Valley, and a traditional labyrinth. For more information, visit the Sanctuary Cove website.

Top guest favorite

The guesthouse is set against a backdrop of desert landscape, showcasing a simple, earthy exterior. A wooden porch with railings invites guests to enjoy the outdoor space. Desert vegetation, including cacti and shrubs, enhances the natural surroundings, along with rocky pathways leading to the house.

Guesthouse in Tucson

4.99 out of 5 average rating, 347 reviews

West-side Trailhead Retreat in the Sonoran Desert

2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Top guest favorite

The entrance features a covered porch supported by wooden beams, overlooking a spacious front yard with desert landscaping. Potted plants are placed beside the steps, and mature trees provide shade, enhancing the serene ambiance of the adobe bungalow.

Home in Tucson

4.99 out of 5 average rating, 118 reviews

Charming Vintage Adobe Bungalow, Central Location

1937 adobe bungalow, located in the historic Palo Verde neighborhood, just minutes away from UofA, downtown, Banner Medical Center, Tucson Botanical Gardens and a few blocks from The Arizona Inn. Thick adobe walls and double-pane windows make it a quiet retreat. Enjoy the covered patio, mature well-tended desert landscape--front and back--and a private outdoor shower. Combines contemporary convenience with vintage charm, including high-end appliances and a cabinet/desk/murphy bed combination

Top guest favorite

The exterior of a straw bale guesthouse is displayed, featuring a covered porch supported by wooden beams. A dining table with chairs is positioned on the porch, surrounded by desert landscaping and gravel. Sunlight is observed casting shadows, highlighting the building's blue walls and green roof.

Guesthouse in Tucson

4.98 out of 5 average rating, 173 reviews

Straw bale guesthouse on Tucson's west side

Beautiful straw bale guesthouse with the best porch in the city! Enjoy incredible sunrises with sweeping views of the Tucson basin. Close to Sweetwater Preserve and Saguaro Nat'l Park West it makes for a perfect place to rest after a long day of hiking or mountain biking. Enjoy the peaceful nature of the country with convenience of being only 5 minutes from the freeway and a 15 minute drive to downtown. Private parking, a fully remodeled kitchen, 1 bedroom with king sized bed and day bed.

Top guest favorite

The exterior of a historic adobe property is shown, featuring a combination of white stucco and exposed stone. Lush greenery surrounds the entrance, with paths leading to wooden doors. Notable is the distinctive architectural style, reflecting the character of Tucson's Barrio Viejo.

Home in Tucson

4.93 out of 5 average rating, 176 reviews

Cimarrones Barrio Viejo

Cimarrones is an historic property located in the heart of Tucson's charming Barrio Viejo. Completely renovated in 2021, the building is now a duplex, with Cimarrones fronting the picturesque street. While the charm of the historic elements - the thick adobe walls, high ceilings with wood vigas, brick paver floors - has been preserved, a selective choice of luxury contemporary conveniences, fixtures and finishes will make your stay supremely comfortable. Arizona TPT License # 21469803

Top guest favorite

The exterior of the Time Capsule is displayed, featuring a circular design with vibrant purple walls and a wooden deck. Two orange chairs are positioned on the deck, surrounded by desert vegetation. The minimalist structure is set against a clear blue sky.

Guesthouse in Tucson

4.99 out of 5 average rating, 369 reviews

Time Capsule in the Sonoran Desert

Time Capsule is a unique experience in an space age module dropped in the middle of an 11 acres desert sanctuary and sculpture park, adjacent to the Saguaro National Park. Enjoy the quietness of the desert in a safe environment located at just 35 minutes from downtown Tucson. Because of the refinement of the interior design we cannot accept any pet, service animal, nor children in the Time Capsule. Please note that check in is in person only and not later than 10:00PM. No exception!

Guest favorite

A modern home is positioned amidst the rolling foothills of the Tucson Mountains, surrounded by native desert flora including tall cacti. The expansive sky transitions from blue to a lighter hue, complementing the serene desert landscape.

Chalet in Tucson

4.89 out of 5 average rating, 182 reviews

Tucson Mountain Retreat

Stunningly beautiful mountain and city views!!! Relax on the spacious patio or in the heated spa with a favorite beverage and enjoy the wildlife and views. This home is situated in the foothills of the majestic giant Saguaro-studded Tucson Mountains, with easy access to the Desert Museum, Old Tucson Studios, Gates Pass, Tucson Mountain Park and the Sweetwater Preserve with outstanding biking and hiking trails. Downtown Tucson, U. of Arizona, and 4 golf courses are within 7-10 miles.

Top guest favorite

A modern kitchen is showcased with wooden cabinetry and dark appliances. A spacious white countertop extends into a breakfast bar with two wooden stools. A door leading to the outside is visible, framed by natural light, creating an open and inviting atmosphere.

Guesthouse in Tucson

4.97 out of 5 average rating, 168 reviews

The Coop- Luxury guest house with ideal location

This luxury guest home was originally a chicken coop for a farmer over 60 years who owned the majority of the land in the area. With an addition and a complete renovation, we have designed this for the perfect vacation rental ideally located in Tucson. 15 minutes to Banner and the U of A. 10 minutes to Oro Valley or the freeway. The stylish guest home is separated from our home and designed with privacy in mind. Enjoy this brand new house for your stay with experienced hosts.

Top guest favorite

An inviting entrance showcases a wooden door with multiple panels, leading to a simple, open corridor. A framed artwork of a rider adorns the wall, while a cow skull adds a rustic touch above the doorway. Minimalist furnishings include a wooden bench and decorative cushions.

Home in Tucson

4.99 out of 5 average rating, 329 reviews

1870 Adobe | Barrio Viejo | fire pit | downtwn

This unique, spacious, updated & authentic adobe is located in the historic Barrio Viejo of Tucson, nestled between downtown and Five Points. This desert Adobe has been abandoned since the 1970’s, but is now revitalized with new amenities, exposing the beautiful adobe walls and preserving the original ceilings. The fully stocked kitchen includes a gas range, dishwasher and granite countertops. Enjoy the smart TV in both the bedroom and living room.