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House vacation rentals in Antioquia

Find and book unique houses on Airbnb

Top-rated house rentals in Antioquia

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
Home in Guatape
4.89 out of 5 average rating, 409 reviews

Private house, Lake access Spa experiences

100% privado. Este lugar especial se encuentra en una de las zonas más hermosa de Colombia, rodeado de una vista lacustre 15 km Despertarás en medio de la belleza natural, refrescando tu mente y alma al instante. Hemos creado experiencias a medida,cocina tradicional , chef , experiencias acuaticas y nuestro Spa qué llegara hasta ti para ofrecerte el momento unico qué tu mereces . nuestro concepto es orgánico,confort y privacidad disfruta de la piscina natural y reconecta con la naturaleza.

Top guest favorite
The interior space features a striking vaulted ceiling with wooden beams, creating a sense of openness. Large glass windows highlight panoramic views of the surrounding landscape. Comfortable seating is arranged near a wooden coffee table, while a kitchen area is visible in the background.
Home in Antioquia
4.95 out of 5 average rating, 241 reviews

Lakefront Arc House-10 Min to Guatape, Lake Access

* The lake levels are back & the docks are floating! * Experience the awe-inspiring Arc House, an architecturally designed gem on a private bay, just 10 minutes from Guatape. Glass walls, 20-foot ceilings, and panoramic nature views make it truly unique. The house features 2 queen bedrooms, ensuite bathrooms, balconies, and a sofa in the living area to accommodate a total of 6 people. The high-quality kitchen is a chef's dream, complemented by a dining table for 6 and a lake-view balcony.

Guest favorite
A spacious sleeping area features a large bed with crisp white linens. Soft lighting enhances the warmth of the neutral-toned walls. A flat-screen TV is mounted on the wall opposite the bed, while a staircase leads to a lofted area in the background.
Home in Medellín
4.92 out of 5 average rating, 131 reviews

Newly Designed Duplex in Laureles with Wi-Fi & A/C

Experience Medellín from this stylish and inviting duplex with a modern urban feel. The bedroom is on the lower level, while the living room, kitchen, and bathroom are upstairs with a comfortable flow between spaces. Street-facing windows fill the home with natural light and fresh air. Located in a walkable, vibrant neighborhood with easy access to public transportation, cafés, supermarkets, and restaurants. High-speed internet makes it ideal for remote work and city explorers alike.

Top guest favorite
A spacious outdoor deck features a wooden floor and a covered lounge area with seating and a hot tub. The backdrop showcases a stunning view of the Peñol Rock and surrounding lush mountains, while a serene waterway flows nearby.
Home in El Peñol
4.98 out of 5 average rating, 115 reviews

New Luxury Cabin Jacuzzi Sauna Fireplace Best View

Spacious home featuring two Queen-size beds, one double bed, and two single beds, with an additional sofa bed that can be used as a double bed! Everything you could wish for in a property with the best view of the beautiful mountains and the iconic Peñol Rock, one of the most visited attractions in Antioquia. The amenities speak for themselves in a central & easily accessible location, reachable by car, and just a two-block walk to the nearby marina so you can rent my Jetski & boat!

Luxe
Home in Medellín
4.99 out of 5 average rating, 124 reviews

Casa Alba Luxury Villa-Pool-15min to Provenza

1. Luxury Retreat: Unparalleled seclusion in Medellin. 2. Stunning Views: Overlooking Poblado 3. Privacy: Total escape from daily life. 4. Convenient Access: Easy access to the airport. 5. Heated Pool: Year-round relaxation. 6. Jacuzzi: Private and calming atmosphere. 7. Outdoor Amenities: Fireplace & kitchen for al fresco dining. 8. Air Conditioning: Each bedroom offers AC 9. Nightlife: Close to vibrant city nightlife. 15mins drive 10. Daily housekeeping

Guest favorite
Home in Guatape
4.82 out of 5 average rating, 212 reviews

A little house with access to the lake and a view of the stone, Guatape

Your stay includes free use of kayaks and bicycles (with a refundable deposit), so you can enjoy the reservoir and its surroundings. This authentic little Antioquia house is perfect for couples or small groups looking for a place full of charm. As the reviews show, it is a magical space that exceeds expectations and is usually even more beautiful than what the photos show. Private access to the reservoir, large green areas, and close to the Piedra del Peñol and the main road.

Top guest favorite
An outdoor area is illuminated at night, featuring a private pool with a water feature and a jacuzzi. A spacious seating arrangement with a dining table is visible beside the pool, with the modern house in the background showcasing large windows and an open design.
Home in Santa Fe de Antioquia
4.97 out of 5 average rating, 111 reviews

Modern Villa with a pool and private Jacuzzi!

Modern house with a swimming pool and private Jacuzzi, (Rates from 6 to 10 people), with luxury finishes, spacious and fully equipped for a very comfortable stay. An ideal place to relax, unwind and share unforgettable moments with family, as a couple and with friends. Located two blocks from the main park of Santa Fe de Antioquia, a magical place of great historical and cultural richness, its colonial architecture and well-preserved cobblestone streets are a national heritage.

Top guest favorite
Home in Santa Fe de Antioquia
5 out of 5 average rating, 10 reviews

Farm near Medellín

Residence 40 minutes from Medellín, warm climate. Luxury retreat near Medellín in a private and exclusive setting. Enjoy an infinity pool, hot tub, fire pit, BBQ, and outdoor movie theater. Designer house with 3 bedrooms, 6 beds, and 4 bathrooms. Fully equipped gourmet kitchen, built-in sound system, and ideal spaces for unique experiences. Perfect for premium stays or private events (by reservation). Security with external monitoring and 24/7 housekeeping service.

Top guest favorite
Two white lounge chairs are positioned near a round, tiled jacuzzi surrounded by vibrant flowering plants. A shaded patio set and umbrella are visible in the background, adding to the inviting outdoor space. Bright blue skies create a cheerful atmosphere.
Home in Santafé de Antioquia
4.89 out of 5 average rating, 210 reviews

Beautiful Colonial House in Santa Fe, Antioquia, A/C

Beautiful and cool colonial house in Santa Fe de Antioquia, 4 spacious rooms with A/C, common areas, and a jacuzzi. Great location. Just two blocks from the main park. Two cool and spacious patios for enjoyment. 950 m2 of built-up area. It is a space for families looking for a private, central location where you won't be affected by noise, where everything will be close by, and where you can enjoy all the amenities of this beautiful colonial city.

Guest favorite
A wooden jacuzzi is positioned on a deck, offering sweeping views of green mountains. A basket filled with colorful towels sits nearby, complementing the serene setting. Lush plants frame the scene, enhancing the natural ambiance.
Home in Titiribí
4.93 out of 5 average rating, 120 reviews

Casa Ceiba - The Forest

Discover the magic of Titiribí, Antioquia, in our spectacular house with unparalleled views. Relax in the Jacuzzi or cool off in the pool while enjoying a unique natural setting. This cozy space is perfect for couples or friends. With spacious common areas and all the amenities you need, your stay will be unforgettable. Come and live an experience of tranquility and beauty in the middle of the mountains! Book now and make your trip special

Superhost
A charming house with a classic terracotta roof is set amidst rolling mountains. Surrounded by greenery, the exterior features a spacious porch with hanging plants. A vehicle is parked nearby on the well-maintained grassy area, providing easy access to the property.
Home in Barbosa
4.89 out of 5 average rating, 230 reviews

House with an Incredible View - 7 nights 15% off

Beautiful house in the mountains. 42 km (26 miles) from Medellín, (40 minutes from the exit of Bello) Please note there is one (1) toll on the route. Ideal for resting or working away from the city. A private place with great spaces for outdoor activities, away from noise and stress. Thanks to our guests' recommendations: - We installed new mattresses - We added Wi-Fi to our property

Guest favorite
Home in El Carmen de Viboral
4.86 out of 5 average rating, 106 reviews

Entire farmhouse | Nature & relax in el carmen v

Embark on the authentic experience of the Colombian countryside in our beautiful estate, where nature and hospitality come together to offer you unforgettable vacations. Wake up to the wonderful singing and sighting of local birds, while the tranquility and connection with the nature, culture, and biodiversity of the region ensure unforgettable moments with your family and friends.

Popular amenities for Antioquia house rentals

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