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House vacation rentals in Antioquia

Find and book unique houses on Airbnb

Top-rated house rentals in Antioquia

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Fredonia
4.96 out of 5 average rating, 45 reviews

Hacienda Naya: Pool, Views & Waterfalls

Escape to Hacienda Naya, a private coffee-farm retreat with valley views, waterfalls, a pool, and space for up to 13 guests. Some mornings, the hacienda feels as if it’s floating above the clouds. Swim with a view, wake to birdsong, breathe the mountain air, tour the coffee fields, or immerse yourself in the waterfall’s sound, mist, and calm. Guests often arrive with plans, then slow down into quiet nights, long views, and meals prepared by an optional local cook, so everyone can truly relax.

Top guest favorite
The interior space features a striking vaulted ceiling with wooden beams, creating a sense of openness. Large glass windows highlight panoramic views of the surrounding landscape. Comfortable seating is arranged near a wooden coffee table, while a kitchen area is visible in the background.
Home
4.95 out of 5 average rating, 261 reviews

Lakefront Arc House-10 Min to Guatape, Lake Access

* The lake levels are back & the docks are floating! * Experience the awe-inspiring Arc House, an architecturally designed gem on a private bay, just 10 minutes from Guatape. Glass walls, 20-foot ceilings, and panoramic nature views make it truly unique. The house features 2 queen bedrooms, ensuite bathrooms, balconies, and a sofa in the living area to accommodate a total of 6 people. The high-quality kitchen is a chef's dream, complemented by a dining table for 6 and a lake-view balcony.

Guest favorite
An infinity pool overlooks lush green hills and a serene dam, providing panoramic views of the surrounding natural landscape. The vibrant sky contrasts with the tranquil water, inviting guests to immerse themselves in the picturesque environment.
Home in San Rafael
4.9 out of 5 average rating, 146 reviews

Private 15-Bed Finca Infinity Pool | Near Guatapé

Only one group at a time – total privacy on our 86-acre private finca with infinity pool. Perfect for reunions, weddings & corporate getaways. Min 10 | Sleeps 48. Base rate covers 10 guests. Extra 11-16 charged per person. For 17-48: book 16 now (Instant Book), message final headcount. We adjust the fee cleanly through Airbnb. • Infinity pool + jacuzzi & sauna • 15 bedrooms | 18 baths | Kitchen for 48 • Starlink Wi-Fi | Solar power ✅ All taxes and fees included | 📆 Flexible cancellation

Top guest favorite
An outdoor seating area is shown, featuring a small round table surrounded by two chairs. A warm fire is seen in a metal fire pit, while rain falls lightly, creating a cozy ambiance. Lush greenery borders the space, with soft lighting illuminating the scene.
Home in Rionegro
4.91 out of 5 average rating, 107 reviews

A small farm 2 minutes away from Rionegro Airport

Finquita La Fortuna, ideal for being close to Rionegro's JMC MDE Airport, just 2 minutes away, with convenient 24-hour transportation; 15 minutes from Medellín and Santa Elena; Arví Park; a safe and central area; close to the María Madre de Dios parish; La Mal Sentada Túnel restaurant; Capitulo by Relato restaurant; La Matriarca restaurant; private entrance; private parking; campfire area; BBQ or charcoal grill; nearby minimarket, pharmacies, shopping centers, and a horseback riding center.

Top guest favorite
A spacious outdoor deck features a wooden floor and a covered lounge area with seating and a hot tub. The backdrop showcases a stunning view of the Peñol Rock and surrounding lush mountains, while a serene waterway flows nearby.
Home in Peñol
4.98 out of 5 average rating, 126 reviews

New Luxury Cabin Jacuzzi Sauna Fireplace Best View

Spacious home featuring two Queen-size beds, one double bed, and two single beds, with an additional sofa bed that can be used as a double bed! Everything you could wish for in a property with the best view of the beautiful mountains and the iconic Peñol Rock, one of the most visited attractions in Antioquia. The amenities speak for themselves in a central & easily accessible location, reachable by car, and just a two-block walk to the nearby marina so you can rent my Jetski & boat!

Top guest favorite
An outdoor area is illuminated at night, featuring a private pool with a water feature and a jacuzzi. A spacious seating arrangement with a dining table is visible beside the pool, with the modern house in the background showcasing large windows and an open design.
Home in Santa Fe de Antioquia
4.97 out of 5 average rating, 114 reviews

Modern Villa with a pool and private Jacuzzi!

Modern house with a swimming pool and private Jacuzzi, (Rates from 6 to 10 people), with luxury finishes, spacious and fully equipped for a very comfortable stay. An ideal place to relax, unwind and share unforgettable moments with family, as a couple and with friends. Located two blocks from the main park of Santa Fe de Antioquia, a magical place of great historical and cultural richness, its colonial architecture and well-preserved cobblestone streets are a national heritage.

Guest favorite
Home in Guatapé
4.83 out of 5 average rating, 224 reviews

A little house with access to the lake and a view of the stone, Guatape

Your stay includes free use of kayaks and bicycles (with a refundable deposit), so you can enjoy the reservoir and its surroundings. This authentic little Antioquia house is perfect for couples or small groups looking for a place full of charm. As the reviews show, it is a magical space that exceeds expectations and is usually even more beautiful than what the photos show. Private access to the reservoir, large green areas, and close to the Piedra del Peñol and the main road.

Top guest favorite
The exterior of a modern two-story house is visible, featuring a light green facade and large windows. A gated area with black fencing surrounds the property, complemented by lush palm trees. The driveway is accessible from the street, with a covered area for outdoor storage.
Home in Floresta
4.93 out of 5 average rating, 167 reviews

Large modern safe and downtown.

Bring the whole family to this fantastic place, very spacious spaces with premium finishes, spacious rooms, comfortable modern and independent bathrooms, with beautiful views in each of its rooms. This beautiful and modern house has an electronic private parking lot, a modern and fully endowed kitchen and a spacious viewpoint. Located in one of the more traditional and central neighborhoods in Medellin, it will make you feel at home. Few dates available. Bus routes and taxi.

Superhost
Home in Sopetrán
4.81 out of 5 average rating, 136 reviews

Casa Utopia Pool View BBQ Air Conditioning and Wifi

Casa Utopía is the mix you're looking for: 🏞️Excellent views of the Antioquia Mountains 🏊‍♂️ Private pool and BBQ - Barrel Grill ❄️ Air conditioning in all 3 bedrooms (20 Guests) 💻Fast Wi-Fi (Starlink) and space to work. Spend the day between dips, barbecues, and hammock naps. At night, movies on Smart TV and clear skies. Quiet location 10 minutes from Sopetrán Park and 20 minutes from Santa Fé de Antioquia, with easy access and total privacy. Secure your dates!

Superhost
Home in Santa Fe de Antioquia
4.71 out of 5 average rating, 14 reviews

Farm near Medellín

Residence 40 minutes from Medellín, warm climate. Luxury retreat near Medellín in a private and exclusive setting. Enjoy an infinity pool, hot tub, fire pit, BBQ, and outdoor movie theater. Designer house with 3 bedrooms, 6 beds, and 4 bathrooms. Fully equipped gourmet kitchen, built-in sound system, and ideal spaces for unique experiences. Perfect for premium stays or private events (by reservation). Security with external monitoring and 24/7 housekeeping service.

Top guest favorite
A wooden jacuzzi is positioned on a deck, offering sweeping views of green mountains. A basket filled with colorful towels sits nearby, complementing the serene setting. Lush plants frame the scene, enhancing the natural ambiance.
Home in Titiribí
4.93 out of 5 average rating, 129 reviews

Casa Ceiba - The Forest

Discover the magic of Titiribí, Antioquia, in our spectacular house with unparalleled views. Relax in the Jacuzzi or cool off in the pool while enjoying a unique natural setting. This cozy space is perfect for couples or friends. With spacious common areas and all the amenities you need, your stay will be unforgettable. Come and live an experience of tranquility and beauty in the middle of the mountains! Book now and make your trip special

Superhost
A large swimming pool with a mosaic tiled surface is surrounded by palm trees. The clear blue water reflects the sky, creating a serene atmosphere. The pool area is spacious, providing ample space for relaxation and enjoyment.
Home in San Jerónimo
4.83 out of 5 average rating, 117 reviews

Cozy House in San Jerónimo / 5 Min from the Park

Enjoy the comfort of this luxurious 4 bedroom, 3 bathroom house, with stunning resort-style facilities, located in San Jerónimo. Located in an exclusive residential community, it is perfect for escaping the hustle and bustle of the city, and just minutes from San Jerónimo's main park. ✔ A pool Fully equipped✔ kitchens ✔ Smart TVs High-speed ✔ Wi-Fi Free ✔ parking ✔ Gym Soccer ✔ field ✔ Tennis court Find out more below!" ✨🌴🏡

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