House vacation rentals in Panama
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Top-rated house rentals in Panama
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama house rentals
House rentals with a pool
Home in Panama
4.96 out of 5 average rating, 138 reviewsVilla Isabella in Coronado Beach Panama
Home in contadora
4.86 out of 5 average rating, 195 reviewsvilla in counter, pearls
Home in Panama City
4.9 out of 5 average rating, 31 reviewsBeautiful house with private pool
Home in Playa Mata Oscura
4.92 out of 5 average rating, 25 reviewsCasa De Ola, Jungle Beach Cabin
Home in Playa Venao
5.0 out of 5 average rating, 17 reviewsCasa Samambaia - sea view tropical paradise w pool
Home in Playa Bluff
5.0 out of 5 average rating, 17 reviewsJungle House 100m from the beach
Home in Río Hato
4.95 out of 5 average rating, 75 reviewsSpectacular beachfront house in Buenaventura!
Home in San Carlos
4.93 out of 5 average rating, 88 reviewsBeach House-Ocean View Rooftop Jacuzzi & Pool
Weekly house rentals
Home in Santa Catalina
5.0 out of 5 average rating, 25 reviewsCasa Colibrí - modern house in the green
Home in Boquete
5.0 out of 5 average rating, 64 reviewsAlba Verde Guest House, Private Vacation Rental
Home in Boquete
5.0 out of 5 average rating, 12 reviewsCaturra Casita @ Finca Panda
Home in Bocas del Toro
5.0 out of 5 average rating, 21 reviewsTropical Paradise, Oceanfront Home in the Jungle
Home in La Guaira
4.96 out of 5 average rating, 83 reviewsPuntita Manzanillo, fantastic sea and jungle
Home in Nueva California
5.0 out of 5 average rating, 12 reviewsSpacious 3 bedroom house in Volcan cloud forest
Home in Panamá
5.0 out of 5 average rating, 9 reviewsUnique 4 room house - direct access to the beach
Home in Bocas del Toro
4.9 out of 5 average rating, 10 reviewsLa Casita Barrbra BnB
Private house rentals
Home in Chame
4.86 out of 5 average rating, 14 reviewsEscape the city! Cozy weather and home.
Home in Bull Beach
5.0 out of 5 average rating, 12 reviewsYellowfin Casa 3
Home in Colón Island
4.93 out of 5 average rating, 80 reviewsVery Nice One bedroom Apartment over the Caribbean
Home in Playa Venao
5.0 out of 5 average rating, 13 reviewsNearly Oceanfront: Blue 3 Bedroom Spacious Villa
Home in Torio
5.0 out of 5 average rating, 14 reviewsIdeal Creative Retreat Immersed in Forest
Home in Gamboa
4.86 out of 5 average rating, 88 reviewsBirdHouse@ Gamboa Panamá Canal
Home in Jaramillo Arriba
5.0 out of 5 average rating, 4 reviewsSpectacular House in Boquete w/King Beds & Hot Tub
Home in Panamá
4.96 out of 5 average rating, 45 reviewsCozy cabin in the mountains of Cerro Azul
Destinations to explore
- Rentals with an accessible height bed Panama
- Rentals with beach access Panama
- Smoking-friendly rentals Panama
- Rentals with a sauna Panama
- Cottage rentals Panama
- Boutique hotel rentals Panama
- Rentals with breakfast Panama
- Rentals with a patio Panama
- Hotel rentals Panama
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- Private suite rentals Panama
- Rentals with a fire pit Panama
- Rentals with a home theater Panama
- Fitness-friendly rentals Panama
- Chalet rentals Panama
- Bungalow rentals Panama
- Nature eco lodge rentals Panama
- Waterfront rentals Panama
- Beach condo rentals Panama
- Bed and breakfasts Panama
- Rentals with a fireplace Panama
- Pet-friendly rentals Panama
- Treehouse rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Monthly Rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Apartment rentals Panama
- Loft rentals Panama
- Boat rentals Panama
- Villa rentals Panama
- Family-friendly rentals Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Condo rentals Panama
- Kid-friendly rentals Panama
- Rentals with a hot tub Panama
- Wheelchair accessible rentals Panama
- Farmstay rentals Panama
- Rentals with pools Panama
- Rentals with lake access Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Tiny house rentals Panama
- Beach house rentals Panama
- Island rentals Panama
- Vacation home rentals Panama
- House rentals Panama City
- Guesthouse rentals Panama City
- House rentals Playa Coronado
- House rentals Altos del Maria
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