Guesthouse vacation rentals in Charleston
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Top-rated guesthouse rentals in Charleston
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Charleston guesthouse rentals
Family-friendly guest house rentals
Guesthouse in North Charleston
4.94 out of 5 average rating, 350 reviewsCozy Park Circle, Charleston Guest House
Guesthouse in North Charleston
5.0 out of 5 average rating, 113 reviewsThe Park Circle Clerestory Studio Guest House
Guesthouse in Charleston
4.91 out of 5 average rating, 653 reviewsIsland Oasis—Near Downtown
Guesthouse in Summerville
4.94 out of 5 average rating, 215 reviewsNina's Cottage -Historic Downtown Summerville
Guesthouse in Mount Pleasant
4.95 out of 5 average rating, 228 reviewsGreen Garden Studio @greengardenstudio2017
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 100 reviews5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!
Guesthouse in Johns Island
4.98 out of 5 average rating, 240 reviewsPrivate waterfront apt in the oaks
Guesthouse in North Charleston
4.86 out of 5 average rating, 446 reviewsPark Circle Jungalow Loft
Guest house rentals with a patio
Guesthouse in Johns Island
4.91 out of 5 average rating, 113 reviewsCozy Cottage! 5 mins from Kiawah!
Guesthouse in Charleston
4.96 out of 5 average rating, 132 reviewsStudio Apartment Minutes to Downtown Charleston
Guesthouse in Charleston
4.98 out of 5 average rating, 127 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Hanahan
4.99 out of 5 average rating, 82 reviewsThe Violet Villa w/ no cleaning fee
Guesthouse in Charleston
4.94 out of 5 average rating, 82 reviewsSpacious 1 bedroom cottage in Avondale
Guesthouse in Charleston
4.95 out of 5 average rating, 93 reviewsBoHo styled casita in adorable neighborhood...
Guesthouse in Goose Creek
4.96 out of 5 average rating, 51 reviewsThe Blue Secret
Guesthouse in Charleston
4.99 out of 5 average rating, 77 reviewsThe James: “Tiny” Home b/w Downtown & Folly
Guest house rentals with a washer and dryer
Guesthouse in Summerville
4.97 out of 5 average rating, 221 reviewsTiny Oak Cottage in Historic Downtown Summerville
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 119 reviewsBeach, downtown, Alhambra Hall weddings so close!
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 224 reviewsCozy Apartment in Mount Pleasant
Guesthouse in North Charleston
4.94 out of 5 average rating, 117 reviewsNewly Renovated Studio in Park Circle
Guesthouse in Charleston
5.0 out of 5 average rating, 222 reviewsJames Island "La Casita" Nestled btw Beach & City
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 260 reviews#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
Guesthouse in Charleston
4.98 out of 5 average rating, 245 reviewsDetached Guest Suite
Guesthouse in Charleston
4.99 out of 5 average rating, 149 reviewsLarge Guesthouse with Private Dock & Marsh Views
Quick stats about guesthouse rentals in Charleston
Total rentals
230 properties
Rentals with dedicated workspaces
100 properties have a dedicated workspace
Rentals with a pool
10 properties have a pool
Pet-friendly rentals
50 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
23K reviews
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