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Vacation rentals in Santiago

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santiago

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Apartment in Santiago de los Caballeros
4.91 out of 5 average rating, 231 reviews

{Minimalist Haven} @Centro +Piscina+Vista+ GYM

Este lugar único tiene su propio estilo. Apartamento nuevo, decorado pensando en cada detalle entre el lujo y la modernidad. Nuestro alojamiento cumple con todas las expectativas a la hora de pasar un momento único. Se encuentra en una de las zonas más tranquilas y prestigiosas de Santiago, La Esmeralda. Podrá disfrutar de todas las comodidades en nuestro alojamiento, las mejores vistas de Santiago desde nuestro rooftop con piscina y gimnasio. ¡Recibirá un servicio exclusivo y de lujo!.

Top guest favorite
Apartment in Santiago de los Caballeros
5 out of 5 average rating, 17 reviews

Brand-New 2BR Luxury Apartment w/ Pool, Gym &Sauna

Enjoy modern living in this brand-new 2-bedroom apartment featuring resort-style amenities and a beautiful view of the Monumento. The bright, contemporary space is designed for comfort and easy living. Residents have access to a pool, sauna, fully equipped gym, BBQ area, and a playroom with ping pong, plus a dedicated infant play area, making it ideal for both relaxation and family-friendly living. A perfect blend of comfort, convenience, and lifestyle in a truly exceptional setting.

Guest favorite
Home in Santiago de los Caballeros
5 out of 5 average rating, 12 reviews

Alpine River Cabin with direct access to the river

30 minutes from Sajoma, Alpina del Río is a private villa surrounded by mountains, ideal for resting and disconnecting from the noise of the city. It offers direct access to the river, a 5-minute walk and 2-minute drive. It has a private pool, large patio, BBQ area, living room, dining room, equipped kitchen, washing machine, 2 bedrooms with large beds, 2 full bathrooms and 1 half bathroom, air conditioning, Wi-Fi and comfortable furniture. Great for couples or small parties.

Guest favorite
A cozy living area features a light-colored sectional sofa adorned with decorative cushions. A wooden coffee table is positioned in front, with a television mounted on the wall opposite. Natural light filters through sheer curtains, highlighting a decorative plant in the corner.
Apartment in Santiago de los Caballeros
4.98 out of 5 average rating, 83 reviews

Warm and comfortable 2 bedroom apartment 2 parking spaces

Discover a beautiful 2-bedroom apartment designed to make you feel at home from the moment you arrive. With a minimalist style and carefully thought-out details, this space offers you the tranquility, harmony and comfort you need, whether to rest, work or explore the city. Every corner has been created with love, combining spaces with soft colors and a cozy atmosphere that will allow you to enjoy a comfortable and tasteful stay. It will be a pleasure to welcome you❤️

Superhost
Home in Santiago de los Caballeros
4.73 out of 5 average rating, 11 reviews

#1 Villa Exclusive w/ Private Pool & BBQ Santiago

Imagine waking up in a modern villa in the hearth of Santiago de los Caballeros, enjoying your coffee by the private pool, relaxing in the jacuzzi, and sharing unforgettable moments in the patio with BBQ. Here, every space is designed for comfort, privacy, and a making memories with your family or special friends! We, as Dolce Vita Property Management are here to make your stay unforgettable ! ❤️Save this listing to your favorites so you don’t miss our best offers

Guest favorite
Apartment in Santiago de los Caballeros
4.87 out of 5 average rating, 109 reviews

High Above the City: Luxury Studio&Private Jacuzzi

Disfruta de un estudio exclusivo en un piso alto, diseñado para desconectar del ruido urbano. El plan perfecto: relajarte en tu jacuzzi privado en la terraza mientras contemplas las espectaculares vistas de la ciudad. 🥂💫 🏙️ Piso Alto: Vistas panorámicas y total silencio. 💦 Jacuzzi Privado: Exclusivo en tu terraza. 📍 Centro de Santiago: Cerca de todo, con máxima privacidad. 🔐 Seguridad 24/7: Edificio moderno y acceso controlado. ¡El escape perfecto! 🚀

Guest favorite
Cabin in Pedro García
4.99 out of 5 average rating, 288 reviews

Alpine house

Welcome to Alpina House, an alpine cabin in Pedro García overlooking the river. It features a king-size bed, private balcony, equipped kitchen, Wi-Fi, and air conditioning. Ideal for romantic getaways or relaxing in nature. Nearby there are hiking trails, bike rides, and dining options. Enjoy a one-of-a-kind experience in a quiet and cozy setting! Heated jacuzzi and bathtub with a cozy living room on the second level. Come and experience this magical place...

Guest favorite
A modern living room is highlighted by a large TV displaying the Netflix logo. Soft natural light filters through sheer curtains, creating a bright atmosphere. A plush sectional sofa is adorned with a textured throw, while a round coffee table adds a minimalist touch, complemented by decorative elements.
Apartment in Santiago de los Caballeros
4.98 out of 5 average rating, 43 reviews

Exclusive 7th Floor w/ City View & Infinity Pool

Enjoy this brand-new 7th-floor apartment in a modern tower with elevator, stylish lobby, and 24/7 security. Features A/C and smart TVs in all bedrooms and living room, plus a spacious balcony with stunning views of La Esmeralda and Villa Olga. Two-level social area includes a meeting room, gym, panoramic terraces, BBQ zone, and an infinity pool overlooking the Monument and the city. Private parking included. Perfect comfort and style in a prime location.

Guest favorite
Villa in Santiago de los Caballeros
4.86 out of 5 average rating, 80 reviews

Mountain * Paradise * Pool * Wi-Fi * King bed *

Escape to a private tropical oasis just 15 mins from Santiago & 30 mins from STI Airport! This isn't just a stay; it’s a resort-style experience featuring a sparkling pool with integrated spa, outdoor chef’s kitchen, Tiki bar, and a 100" HD cinema screen under the stars. Perfect for groups seeking luxury in nature. Enjoy cool mountain breezes, stunning views, and total privacy in this 3-bedroom indoor-outdoor sanctuary. Book your dream getaway today!

Top guest favorite
Apartment in Santiago de los Caballeros
4.96 out of 5 average rating, 27 reviews

Luxury Apartment | Rooftop Pool | Gym & City Views

Enjoy a peaceful stay in one of Santiago’s best areas, close to restaurants, shopping, and entertainment. The apartment features fast WiFi, A/C in all rooms, Smart TVs, a private balcony, and free covered parking. Relax with access to a rooftop pool, fully equipped gym, and social area with stunning city views. Ideally located just 3 minutes from Ágora Mall and only 3 minutes from Unión Médica. Perfect for long stays, couples, or remote work.

Top guest favorite
Apartment in Santiago de los Caballeros
4.99 out of 5 average rating, 138 reviews

Elegant apartment in Panorama | Pool and parking

Exclusive one-bedroom apartment in Soha Panorama, Santiago, located in a prestigious tower with a design in wood and green tones that create a serene and elegant atmosphere. Modern kitchen, spacious room and excellent location. Note: As of August 25, 2026, the pool and gym will be temporarily out of service due to maintenance work by the administration. The social area is located on the 17th floor, so this work will not affect your stay.

Guest favorite
A spacious bedroom is presented, featuring a large bed with quality bedding and decorative pillows. Natural light enters through a window dressed with sheer white curtains. An air conditioning unit is mounted above the bed, and a wooden door provides access to another area.
Apartment in Santiago de los Caballeros
4.87 out of 5 average rating, 171 reviews

Porto 09 Luxury and Relax apt in Santiago City

It will be very easy to plan your visit☺️! This place has a strategic location, in the la esmeralda sector and just behind the international square of Santiago de los Caballeros. This apt is located in one of the most modern buildings in the city and has security in the building 24 hours, beautiful view, gym, swimming pool, rooftop, covered terrace and underground parking!

Popular amenities for Santiago vacation rentals