
House vacation rentals in Santa Isabel
Find and book unique houses on Airbnb
Top-rated house rentals in Santa Isabel
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Isabel house rentals
House rentals with a pool

casa privada completamente equipada

Privacy, charm, and a peaceful city oasis.

Hacienda Florentina with Puerto Rico best views

Malecon Beach House, Steps to the Caribbean Ocean

Vista Hermosa Guest House

Green Hills House

Cozy Nature Escape w/ Pool + Ocean View

Villa Coralina
Weekly house rentals

La Lomita Noly

Fully Equipped! Casa Antolina 2Br/ 1 -1/2 Bath

Bohemian House

Miah House/Pool/Solar Energy/Water Reserve

Casa Gabriela in Salinas

Stunning house w amazing views+

Coral del Caribe- with backup generator & cistern

Misdry House, Salinas
Private house rentals

Monte Oasis: House & Glamping with Pool & Hot Tub

Rancho Mariposa ( relaxing cozy house )

Family vacation home

Oasis del Quijote - House with Private Heated Pool

New! Antique House at Ponce

Casa Mar y Tierra Guayama (Sea and Land House)

Cozy Guesthouse

Brisas del Flamboyan (Flamboyan Breezes)/ 3 Bedroom Home
Destinations to explore
- Punta Cana Vacation rentals
- San Juan Vacation rentals
- Santo Domingo De Guzmán Vacation rentals
- Las Terrenas Vacation rentals
- Santiago De Los Caballeros Vacation rentals
- Santo Domingo Este Vacation rentals
- Sosúa Vacation rentals
- Cabarete Vacation rentals
- La Romana Vacation rentals
- Bayahibe Vacation rentals
- Juan Dolio Vacation rentals
- Carolina Vacation rentals
- Playa del Dorado
- Playa de Vega
- Playa Mar Chiquita
- Playa de Tamarindo
- Distrito T-Mobile
- Playa Puerto Nuevo
- The Saint Regis Bahia Golf Course
- Peñón Brusi
- Los Tubos Beach
- Toro Verde Adventure Park
- Coco Beach Golf Club
- Playa Maunabo
- Beach Planes
- Playa de Cerro Gordo
- Playa de los Cabes
- Playa Puerto Nuevo
- Cueva del Indio
- Cerro Gordo National Park
- Balneario Condado
- Punta Guilarte Beach
- Museo de Arte de Ponce
- Playa Las Palmas
- Playa de Jauca
- Stream Thermal Bath