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Vacation rentals in Santa Ana

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Ana

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A modern two-story building displays a light gray exterior, complemented by tall windows that provide ample natural light. A small garden area with flowering plants is visible at the entrance, and a staircase leads to a private balcony on the second floor.
Home in Managua
4.89 out of 5 average rating, 113 reviews

Cozy Townhouse in Managua!

Enjoy a stylish experience at this centrally-located place! This recently renovated house is located in a safe gated residential area, it takes a seven minutes drive to get to Galerias Santo Domingo mall, restaurants, supermarkets, pharmacies and much more. It offers a private and quiet accommodation for vacationers and business travelers. The unit features a comfortable king sized bed, 1 queen and 1 full sized bed. TV and AC, hot water, washer and dryer, work space and a delightful kitchen.

ValueFamilyLaundry

Guest favorite
A dining area is presented with a round, golden table and four light-colored chairs, creating a welcoming space. A decorative candle holder adorned with faux flowers is visible in the foreground, while a large abstract painting adds a vibrant element to the wall.
Condo in Managua
4.95 out of 5 average rating, 40 reviews

4D| Las Colinas 1 Bedroom A/C Parking 24-hour Security

Oasis of Design, Art and Comfort Las Colinas | 2 rooms with A/C | 24-hour security | Long-term stays | Self check-in | Automatic gate Immerse yourself in this space designed for the modern traveler who doesn't sacrifice comfort, aesthetics, or security. With a prime location, you'll love: Waking up with natural light, enjoying a delicious coffee, full connectivity (Wi-Fi), washer and dryer, hot water, and just steps away from the best restaurants and shopping centers in the city

LocationAccuracyWifi

Guest favorite
Villa in Los Robles
5.0 out of 5 average rating, 5 reviews

Casa moderna con diseño acogedor y seguro

Ubicada en el exclusivo Reparto San Juan, esta moderna y acogedora casa ofrece una ubicación privilegiada cerca al centro de managua. Se encuentra a pocos minutos de los principales puntos de interés de la ciudad, como Metrocentro, Mall Natura, y Galería Santo Domingo. Su excelente localización permite fácil acceso al transporte público (a solo tres cuadras), así como a hospitales, supermercado, restaurantes, catedral, colegios, universidades, discotecas y hoteles.

LocationFamilyPool

Top guest favorite
A private swimming pool is situated beside an outdoor bar and barbecue area. The pool is surrounded by a clean deck, with a wall offering privacy. Large windows of the adjacent room allow for views of the pool area while natural light enters the space.
Home in Managua
5.0 out of 5 average rating, 75 reviews

Exclusive and centrally located house

Whether you're planning a business or leisure stay, Casa HEROS awaits you with comfort, security, and peace of mind. Fully equipped with everything you need: A/C, orthopedic beds, blackout curtains in all rooms, social areas, pool, bar, barbecue, hot water, washer, and dryer. Located in a private residential area at Km 6 on the Masaya Highway, with 24-hour security and just minutes away from shopping centers, restaurants, and the vibrant nightlife district.

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Guest favorite
An elegant villa is depicted with a spacious outdoor terrace overlooking a large swimming pool. Lush greenery surrounds the area, and the bright blue sky complements the inviting atmosphere. The structure features a stylish roof and ample outdoor seating, ideal for relaxation.
Villa in Monte Tabor
5.0 out of 5 average rating, 19 reviews

Camino a la Playa Mansion

Mansión Camino a la Playa is a property that has a guest house and a recreation house. It's like having your own private resort. Food: For an additional cost, you can order food from a menu and it will be delivered. It's delicious and the prices are good. Catering with waiters is also offered. Additionally, all kinds of events were held, at an additional cost. I live in an apartment next to the house; we don't share anything; I have my own space.

LocationFamilyPool

Guest favorite
A spacious bedroom features a large bed adorned with a white coverlet, complemented by a blue accent strip and a colorful decorative pillow. A vibrant piece of wall art adds a touch of color, while the closet doors showcase a modern striped design.
Apartment in Managua
4.81 out of 5 average rating, 86 reviews

Central, Convenient, Comfortable

Cozy private accommodation in Managua, in a central, quiet, and safe area. Ideal for business travelers, tourism, or short and long stays. The space is attached to my home, but it is totally self-contained and private. Close to restaurants, supermarkets, pharmacies, universities, movie theaters, and shopping malls. Public transportation 150 meters away and local food in front of the accommodation. Comfort and an excellent location to feel at home.

ValueLocationGetting around

Guest favorite
Home in Managua
4.79 out of 5 average rating, 24 reviews

Casa El Chocoyero

Welcome to your home away from home. Relax in this unique and quiet getaway on the outskirts of the capital, a refuge on the southern highway. Our cozy and modern accommodation offers you the perfect combination: the tranquility of a safe residential area surrounded by nature and the convenience of being just minutes from key points of the city and the proximity to beautiful beaches. It's the perfect place to enjoy our country's flora and fauna.

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Guest favorite
A spacious living area is seen, featuring a comfortable blue sofa and a mounted television. A coffee table sits on a textured rug, with soft lighting from a floor lamp. The open layout connects to the kitchen and dining area in the background.
Apartment in Managua
4.88 out of 5 average rating, 141 reviews

Central and cozy apartment for four

Hogareño apartment with style for four people in a central area of Managua. Located in Colonia Centroamérica, a neighborhood full of life, with excellent access to public transportation and close to several important shopping and entertainment centers, such as Camino de Oriente and Galerías Santo Domingo. It has a parking space, living room, dining room, equipped kitchen, garden, terrace, two bedrooms and a private bathroom.

LocationValueCleanliness

Superhost
Condo in Managua
5.0 out of 5 average rating, 3 reviews

Premium apartment with city views

Enjoy a comfortable and peaceful stay in this modern, fully equipped apartment. Ideal for families, business travelers, or vacations. Its excellent location allows easy access to restaurants, supermarkets, shopping malls and the main points of interest in Managua. Its excellent location allows easy access to restaurants, supermarkets, shopping malls and the main points of interest in Managua.

ValueLocationView

Top guest favorite
The exterior of the house features a light blue facade complemented by landscaped greenery. Several palm trees and large plants are positioned around a welcoming entryway, which includes two chairs and a small table, providing an inviting atmosphere.
Home in Managua
4.91 out of 5 average rating, 35 reviews

Casa Las Palmeras, Managua, Nicaragua

Casa las Palmeras, Modern, Comfortable and well located. Newly remodeled house ideal for families and groups. Located in a quiet and safe area. Easy access to supermarkets, pharmacies, shops and restaurants. Enjoy a comfortable, safe stay full of details designed for your rest. Whether you are coming for work, health or vacation. Casa Las Palmeras offers you the perfect space to feel at home.

FamilyValueIndoor spaces

Guest favorite
Cabin in El Crucero
4.77 out of 5 average rating, 13 reviews

Quinta Las Cumbres

Escape to Casa Las Cumbres in El Crucero, a private mountain house just 30 minutes from Managua. Enjoy the best weather in Nicaragua, with cool nights of up to 16°C, mist and magical sunsets. Details: 5 spacious rooms with fans 3 baths Firepit with views of Lake Managua, Argentinian steakhouse, Spacious gardens, Playgrounds Wi-Fi

FamilyLocationIndoor spaces

Superhost
Home in Managua
4.81 out of 5 average rating, 21 reviews

Family & Group Retreat · Pool, BBQ, Billiards

Escape to a private oasis in Carretera Sur! Spacious 4-bedroom home with large pool, 2 hot tubs, ranch with 2 BBQ stations and billiard table—perfect for families, groups and retreats. Enjoy AC, fast Wi-Fi and secure parking for up to 5 vehicles in a quiet, green area just minutes from Managua’s restaurants, malls and main roads.

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Popular amenities for Santa Ana vacation rentals