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Vacation rentals in Santa Ana

Find and book unique accommodations on Airbnb

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Popular amenities for Santa Ana vacation rentals

Stay near Santa Ana's top sights

Puerto Salvador Allende62 locals recommend
Teatro Nacional Rubén Darío34 locals recommend
Luis Alfonso Velásquez Flores Park21 locals recommend
Seawall Managua13 locals recommend
Palacio Nacional de la Cultura13 locals recommend
Xolotlan Promenade12 locals recommend

Other great vacation rentals in Santa Ana

Guest favorite
Bungalow in Laguna de Apoyo
5 out of 5 average rating, 23 reviews

Alchemy on the Lake

NeilRating, 5 stars1 month ago
One of the best places Ive ever stayed at. Great host with a great team. Lots of communication and the house leaves nothing to be desired. I will definitely go back. Recommend.
Villa in Laguna De Apoyo
4.68 out of 5 average rating, 25 reviews

Gorgeous retreat on the water of Laguna de Apoyo

ValentinRating, 5 stars4 months ago
Fantastic View and g a great place to stay!!!!
Guest favorite
A serene pool overlooks the expansive Apoyo lagoon, framed by lush palm trees. The tranquil water reflects the clear sky, inviting relaxation. Stone tiles surround the pool, enhancing the outdoor space's natural appeal.
Cottage in Apoyo Lagoon
4.95 out of 5 average rating, 22 reviews

Aguas de Apoyo, Amazing Guest House.

LizRating, 5 stars1 month ago
My family and I love the beautiful location of this home. Waking up yo the lake view dazzles every time! The host is responsive and friendly. Just booked another stay!
Guest favorite
A contemporary single-story home with a modern façade is set amongst lush greenery. A palm tree is positioned prominently in the front yard, complemented by low-maintenance landscaping. A driveway is visible, accommodating a vehicle, while well-defined steps lead to the main entrance.
Home in Esquipulas
4.94 out of 5 average rating, 34 reviews

Casa de Guayo

Marlon R.Rating, 5 stars1 week ago
Excellent place to stay.
Guest favorite
A tranquil swimming pool is surrounded by lush greenery and modern wooden decking. Palm and banana plants flank the pool area, contributing to a serene outdoor environment. The clear blue water reflects the sky above, providing a refreshing focal point.
Home in Granada
4.91 out of 5 average rating, 54 reviews

Stunning modern colonial home.

RobertRating, 5 stars1 week ago
Amazing place, much better than in the pictures! Great pool. Super clean. The host wanted a cleaner to come over every day in our private space and insisted quite a bit on this, he was also unclear about the check in times (Airbnb says 2Pm but it’s really 3PM), communication was confusing and slow. I would definitely recommend this place and especially for the rate it is exceptional value!
Superhost
A colorful hammock is positioned on a private terrace, overlooking a lush garden. In the background, vibrant greenery leads to a scenic view of the landscape under a bright sky, creating a peaceful setting for relaxation.
Bungalow in Masatepe
4.9 out of 5 average rating, 20 reviews

Nice house in a relaxing quiet environment

ChrisRating, 5 stars24 months ago
Writing the standard paragraph or two about my month-long stay would be an insult to my experience at Nel's place. In fact, can write a book filled with praise for this place... I've been in Nicaragua for over three years, and this was by far my fave Airbnb, and definitely in my top 5 globally. During my five years in Nicaragua, I saw the national bird a handful of times. On Nel's farm, I stopped counting. For instance, on one hiking excursion to the lake, I counted eleven and saw three tucans. If you're a nature lover, then this is your spot. The best of all is due to the elevation, it's not as hellish hot as certain places in Nica. Even if does get warm, there's always a nice spacious pool to go and cool off in. My home was equipped with everything, and the internet was great for working from home. Nel is an exceptional host and a lovely person to be around with. Her communication is great, and she really cares about your happiness while hosting you on her beautiful property
A circular hot tub is situated on a patterned tile surface, featuring a blend of earth tones. The water is illuminated by subtle blue lighting, highlighting the smooth stones within. Nearby, a green hose rests against the edge, suggesting maintenance readiness.
Home in Ticuantepe
4.8 out of 5 average rating, 15 reviews

Vacation Rental

AlexandraRating, 5 stars21 months ago
We stayed with my family, a very safe environment with a lot of surveillance, Jesenia was always on the lookout and I send Maria very nice and kind. I came up with an unexpected but they fixed it at the time, we would definitely stay with her again. The house is very clean, quite spacious and cozy!
A private pool area features clear blue water with a fountain creating gentle ripples. Surrounding the pool are potted plants and a lounge chair, enhancing the serene atmosphere. Natural light illuminates the space, highlighting the textured stone wall in the background.
Home in Valle Gotel
4.85 out of 5 average rating, 13 reviews

Casa Santa Fe - The best place for a vacation

RicardoRating, 5 stars6 months ago
Excellent Customer Service Team. Very responsive to any question that I did have. Will stay again in a future trip. Thanks for the Hospitality !
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