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Vacation rentals in Santa Ana

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Ana

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in Managua
5 out of 5 average rating, 11 reviews

Midtown Managua urban guesthouse

Enjoy easy access to everything from this centrally located place. Perfect for the solo traveller or couples. Our newly renovated space includes a private entrance and bathroom. Dedicated work space for guest suite, perfect for getting work done on the go. Large window opens to private garden. Suite has A/C for guest use. Coffeemaker, fridge, microwave oven also included for guest use. 20 minute drive to airport. 24/7 security guard. Close to restaurants, mall, mercados, fritangas, & night life.

Guest favorite
A modern two-story building displays a light gray exterior, complemented by tall windows that provide ample natural light. A small garden area with flowering plants is visible at the entrance, and a staircase leads to a private balcony on the second floor.
Home in Managua
4.94 out of 5 average rating, 108 reviews

Cozy Townhouse in Managua!

Enjoy a stylish experience at this centrally-located place! This recently renovated house is located in a safe gated residential area, it takes a seven minutes drive to get to Galerias Santo Domingo mall, restaurants, supermarkets, pharmacies and much more. It offers a private and quiet accommodation for vacationers and business travelers. The unit features a comfortable king sized bed, 1 queen and 1 full sized bed. TV and AC, hot water, washer and dryer, work space and a delightful kitchen.

Guest favorite
A well-lit living area is showcased, featuring a blue sofa, a small desk with a chair, and a TV on a stand. Neutral-colored tiles cover the floor, and light curtains frame a window. A decorative plant in a pot adds a touch of greenery.
Apartment in Managua
4.94 out of 5 average rating, 67 reviews

Apartment 103: Modern and Safe

Just 10 minutes from the airport, the apartment is ideal for travelers in transit, short getaways, or those who want to explore Nicaragua comfortably. Amenities that will make your stay more pleasant: • Washer and dryer included, so you don't have to worry about washing. • High-speed WiFi, perfect for working or entertaining. • 24/7 security, for your peace of mind. All set for your arrival. Enjoy a comfortable, clean and functional space that will make you feel at home

Top guest favorite
A private swimming pool is situated beside an outdoor bar and barbecue area. The pool is surrounded by a clean deck, with a wall offering privacy. Large windows of the adjacent room allow for views of the pool area while natural light enters the space.
Home in Managua
5 out of 5 average rating, 68 reviews

Exclusive and centrally located house

Whether you're planning a business or leisure stay, Casa HEROS awaits you with comfort, security, and peace of mind. Fully equipped with everything you need: A/C, orthopedic beds, blackout curtains in all rooms, social areas, pool, bar, barbecue, hot water, washer, and dryer. Located in a private residential area at Km 6 on the Masaya Highway, with 24-hour security and just minutes away from shopping centers, restaurants, and the vibrant nightlife district.

Guest favorite
Home in Managua
4.76 out of 5 average rating, 21 reviews

Casa El Chocoyero

Welcome to your home away from home. Relax in this unique and quiet getaway on the outskirts of the capital, a refuge on the southern highway. Our cozy and modern accommodation offers you the perfect combination: the tranquility of a safe residential area surrounded by nature and the convenience of being just minutes from key points of the city and the proximity to beautiful beaches. It's the perfect place to enjoy our country's flora and fauna.

Guest favorite
A spacious living area is seen, featuring a comfortable blue sofa and a mounted television. A coffee table sits on a textured rug, with soft lighting from a floor lamp. The open layout connects to the kitchen and dining area in the background.
Apartment in Managua
4.88 out of 5 average rating, 138 reviews

Central and cozy apartment for four

Hogareño apartamento con estilo para cuatro personas en área céntrica de Managua. Ubicado en la Colonia Centroamérica, una vecindad llena de vida, con excelente acceso a transporte público y cerca de varios centros de comercio y entretenimiento importantes, tales como Camino de Oriente y Galerías Santo Domingo. Cuenta con un espacio de estacionamiento, sala, comedor, cocina equipada, jardín, terraza, dos habitaciones y un baño privado.

Top guest favorite
Condo in Managua
5 out of 5 average rating, 18 reviews

Modern executive apartment with views and parking

Welcome to your temporary home in Managua. Our apartment, with a spectacular view of the city, offers everything you need for a comfortable stay, whether for work or sightseeing. Unbeatable location: A few minutes from Metrocentro, supermarkets, restaurants and public transport. Perfect for exploring Managua with ease. Ideal for: couples, business travellers or tourists looking for comfort, location and an excellent view.

Guest favorite
The exterior of the house features a light blue facade complemented by landscaped greenery. Several palm trees and large plants are positioned around a welcoming entryway, which includes two chairs and a small table, providing an inviting atmosphere.
Home in Managua
4.9 out of 5 average rating, 29 reviews

Casa Las Palmeras, Managua, Nicaragua

Casa las Palmeras, Modern, Comfortable and well located. Newly remodeled house ideal for families and groups. Located in a quiet and safe area. Easy access to supermarkets, pharmacies, shops and restaurants. Enjoy a comfortable, safe stay full of details designed for your rest. Whether you are coming for work, health or vacation. Casa Las Palmeras offers you the perfect space to feel at home.

Superhost
Home in Managua
4.78 out of 5 average rating, 18 reviews

Family & Group Retreat · Pool, BBQ, Billiards

Escape to a private oasis in Carretera Sur! Spacious 4-bedroom home with large pool, 2 hot tubs, ranch with 2 BBQ stations and billiard table—perfect for families, groups and retreats. Enjoy AC, fast Wi-Fi and secure parking for up to 5 vehicles in a quiet, green area just minutes from Managua’s restaurants, malls and main roads.

Guest favorite
Home in Managua
4.96 out of 5 average rating, 139 reviews

C.S Apartment One Modern and cozy

Experience comfort in the heart of Managua Relax in this modern and cozy accommodation that features air conditioning, private parking and a prime location in the city center. Just 20 minutes from Augusto C. Sandino International Airport, Sandino, it's the ideal choice for your stay in Managua, whether for business or pleasure.

Top guest favorite
The kitchen features modern appliances, including a microwave, coffee maker, and refrigerator. A countertop with two stools offers a casual dining space. A gas stove is paired with a stainless steel sink, and wall art adds a touch of color to the serene gray walls.
Apartment in Managua
4.91 out of 5 average rating, 372 reviews

Homeliz, Roble Apartment, 2 bedrooms.

This comfortable, modern and cozy apartment with a central location is part of the HOMELIZ accommodations. It is perfect for 4 people, where you can enjoy with family, friends or business trips. It has two bedrooms with a double bed and A/C in each room, a bathroom and shower and a garage for one vehicle.

Top guest favorite
An inflatable unicorn float is positioned on the shimmering blue surface of a large swimming pool. Lush greenery lines the pool area, with two wooden lounge chairs visible in the background under sunny skies.
Villa in Las Colinas
5 out of 5 average rating, 47 reviews

Luxury Oasis in Las Colinas: Elegant 3-Bdrm Villa

Welcome to your luxurious retreat in Managua's prestigious Las Colinas. This stunning property offers an elegant and relaxing stay for up to six guests. Experience the perfect blend of elegance, comfort, and convenience at this exceptional Airbnb retreat in Managua.

Popular amenities for Santa Ana vacation rentals

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  3. Managua
  4. Managua
  5. Santa Ana