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Vacation rentals in San Luis

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in San Luis

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
An open-concept living area features a sleek gray sofa bed and a dining table for four. The kitchen is equipped with modern cabinetry and essential appliances. A wide window allows natural light to brighten the space, complemented by neutral tile flooring.
Apartment in San Luis
4.88 out of 5 average rating, 8 reviews

Apartment Balcony 201 in San Luis

Imagine waking up every morning and having the cultural richness and beauty of San Luis at your fingertips. The apartment is strategically located just a short walk from the main park, allowing you to easily explore the local charms, its gastronomy and its natural wealth such as waterfalls, rivers and mountains. Feel the authenticity of San Luis. Discover a unique experience that perfectly combines strategic location, incomparable comfort, exceptional comfort, and unparalleled elegance.

Top guest favorite
Guest suite in San Luis
4.92 out of 5 average rating, 51 reviews

La Casita en el Aire - Glamping Mirador San Luis

​Experience the magic at La Casita en el Aire! Just two blocks from the main park in San Luis. Enjoy a rustic and cozy retreat with a bathtub, hot water, minibar and great decor. Marvel at unique sunrises and exceptional views of the mountains and our central mountain range. In San Luis you can go trekking, bird watching, rafting and kayaking, surrounded by rivers and waterfalls. We look forward to welcoming you for an unforgettable experience of adventure and relaxation!

Guest favorite
A private mini pool is featured, surrounded by smooth stone pathways and lush green plants with vibrant orange flowers. The clear water reflects natural light, and a modern glass sliding door leads into the interior of the accommodation.
Home in Doradal
4.96 out of 5 average rating, 98 reviews

Du_Dech Natural House

Our accommodation enjoys an exceptional strategic location, just 4 km from the impressive Cañón del Río Claro, where you can enjoy exciting activities such as: - Rafting - Tubing - Caving Plus, we're just 15 minutes from Doradal, a vibrant destination that offers: - The fascinating Hacienda Naples - The charming "Colombian Santorini" - Spectacular landscapes and waterfalls Come and relax in our peaceful oasis, surrounded by adventures and natural beauty!

Superhost
A natural swimming pool is surrounded by lush greenery, with a child in dark swimwear enjoying the water. Two playful dogs are on a stone path leading to the pool, while an inflatable flamingo floats nearby. The area is tranquil and inviting.
Home in Doradal
4.78 out of 5 average rating, 18 reviews

Jagua Forests

Disconnect from your worries in a quiet and beautiful place, ideal for sharing with family and friends. We are located on the Medellin-Bogota highway with beautiful natural landscapes and surrounded by crystal clear waters, you can do birdwatching or simply enjoy the tourist places offered by the region. We are 28 km from the Hacienda Naples theme park, 7 km from the Cañon del Rio Claro nature reserve, 25 km from the beautiful Danta waterfalls.

Guest favorite
A private pool area is surrounded by lush greenery, featuring colorful inflatables in the water. A shaded dining space is visible, equipped with a table and chairs under a red umbrella. The clear blue sky enhances the serene atmosphere.
Cabin in San Luis
5 out of 5 average rating, 10 reviews

El Sendero Farm

Natural Charm in San Luis: Accommodation with Pool next to the Court and 10 minutes from Charco La Planta Experience the magic of San Luis, Antioquia from a place that has it all! Our cozy accommodation offers you a unique experience of rest, fun and connection with nature. Relax in our private pool, ideal for cooling off after a day exploring the surroundings or enjoying a night under the stars. Located right next to the municipal court

Top guest favorite
Cabin in San Luis
4.97 out of 5 average rating, 38 reviews

Swimming pool, Jacuzzi, rest in nature.

Enjoy privacy surrounded by nature. La Barranca is a very cozy country cabin on a quiet plot with lots of wildlife, warm weather during the day, a little breeze at night, and a spectacular view. The cabin is completely private, not shared with other guests Hot tub with hot water, swimming pool with treated water. Fully equipped indoor and outdoor kitchen. The cabin is located 2 kilometers from the village, paved road, 15 minutes by car.

Superhost
Cabin in San Luis
4.7 out of 5 average rating, 44 reviews

Beautiful cabin with direct and private access to the RIVER

Welcome to the most beautiful cabin in San Luis. We now have a paved road to the cabin We have direct access to the river, the ideal space to connect with nature. Master bedroom on the second floor with private bathroom. 3 beds on the first floor. Equipped kitchen. Living room. Dining room. 2 bathrooms. Wi-Fi We assure you that you will return to this beautiful cabin, its energy is unique 💯

Superhost
A bright dining area is presented, featuring a light wood table surrounded by plastic chairs. Large glass doors lead to an outdoor space, while a wall shelf hosts decorative items and a small plant. Natural light fills the room, emphasizing the open layout.
Vacation home in Las Mercedes
4.89 out of 5 average rating, 93 reviews

Comfortable apartment near Hacienda Napoles

Apartment located in Las Mercedes, just 10 minutes from the Hacienda Nápoles Theme Park and Santorini Colombiano, 20 minutes from the Río Claro Nature Reserve. It is nice, comfortable, ideal to enjoy as a family. It has 3 bedrooms; the master bedroom with private bathroom, guest bathroom, fully-equipped kitchen, refrigerator and laundry area.

Superhost
Cabin in San Luis
4.67 out of 5 average rating, 3 reviews

Spectacular cabin - Private Jacuzzi - Wi-Fi - Parking

Escape to a quiet corner surrounded by nature 🍂 Enjoy an unforgettable experience in our cozy cabin in San Luis, Antioquia. 🏡 Relax in the private Jacuzzi while taking in the natural surroundings, disconnect from stress and experience unique moments as a couple, with friends or as a family. 👩‍❤️‍👨

Top guest favorite
A tranquil pool area is framed by lush palm trees, with a water slide positioned nearby. A vibrant sunset paints the sky in shades of orange and pink, creating a serene backdrop for the space. The setting invites relaxation and enjoyment of nature.
Cabin in Vereda Altavista - Rio Claro
5 out of 5 average rating, 18 reviews

Villa Jardines Estate

Disconnect from your worries in this spacious and serene space full of nature and with an exceptional climate. On the Medellín Bogotá highway, just 5 minutes from the Rio Claro Nature Reserve and 40 minutes from the Naples Hacienda.

Guest favorite
A spacious sleeping area features a large bed with neutral-colored bedding and decorative pillows. Natural wood elements are present in the flooring and furniture, complemented by soft lighting. A woven pendant lamp hangs above, flanked by subtle indoor plants and a large window offering views of the surroundings.
Cabin in San Luis
5 out of 5 average rating, 6 reviews

Beautiful cabin a 15-minute walk to the rivers

Cabaña Zafiro is an enclosed space to offer an experience of relaxation and tranquility in the middle of the forest. Enjoy a natural space with all the comforts of a five-star hotel, a 15-minute walk to the village park and rivers

Guest favorite
Apartment in San Luis
4.88 out of 5 average rating, 16 reviews

GOLD GREEN House

Have fun with the whole family at this stylish accommodation, a quiet, comfortable, elegant place, with details designed to make your experience the best. Close to places of interest. Because you deserve a real break.

Popular amenities for San Luis vacation rentals