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Vacation rentals in San Antonio

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Top-rated vacation rentals in San Antonio

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A rooftop terrace is depicted with a dining table set for breakfast. A plate with a croissant and a glass of orange juice sit beside a mug. The background features city buildings under a partly cloudy sky, enhancing the urban atmosphere.
Apartment in San Antonio
4.93 out of 5 average rating, 76 reviews

Suite in San Antonio with Private Patio and Rooftop

Located in the charming San Antonio neighborhood in Cali. You'll be just a short walk from Bulevar del Río, Calle del Sabor, restaurants, cafes, museums, bars, salsa academies and supermarkets, and just 10 minutes from the Cali Zoo, Cristo Rey, the Botanical Garden and Gato de Tejada. It is a quiet space, ideal for a good night's sleep or remote work, and it has a bonus that is hard to find in this location: a private patio with an outdoor dining area, perfect for breakfast or dinner outdoors.

Guest favorite
A staircase with black metal steps leads upward, set against a backdrop of exposed brick wall. Natural light flows through large wooden windows with bars, illuminating a decorative plant in a woven basket and a glass bottle on the floor.
Apartment in San Antonio
4.91 out of 5 average rating, 76 reviews

Cozy+Unique Loft/Touch of Nature/High Speed WiFi

*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

Guest favorite
The spacious living area features a green sofa adorned with colorful cushions, positioned against a white wall. A large area rug adds warmth under a wooden coffee table. Natural light fills the space through expansive windows, complemented by decorative plants and a textured wall hanging.
Apartment in Santa Teresita
4.93 out of 5 average rating, 41 reviews

Rustic Private APT Near Gato de Tejada -7 Min Walk

Welcome to Indigo! This quiet one-bedroom, one-bathroom unit, is the perfect match for families, couples, solo travelers. We are sure you’ll be impressed with the comfort, style, and sophistication the apartment provides. Immerse yourself into Cali and its magical essence while enjoying our Apartment. Be inspired by its unique location and find yourself mesmerized by everything Cali offers, ranging from top-tier restaurants, bars, shops, and nightlife experiences. We are ready for your visit!

Guest favorite
An inviting dining area features a large wooden table surrounded by six green chairs. Soft light from pendant lamps enhances the open layout, which connects to a cozy living space with a comfortable sectional sofa. Large windows provide ample natural light.
Apartment in El Peñol
4.92 out of 5 average rating, 76 reviews

Spacious & cool apartment in El Peñon

Discover the charm of Cali in this completely renovated apartment, located in the heart of the trendies neighborhood of Cali. Equipped with everything you need to feel at home, from a French press with Colombian coffee to modern appliances such as an airfryer and blender. Two big screen TVs with Netflix for entertainment, washing machine, iron and more, ensuring a comfortable stay. El Peñon is one of the most famous neighborhoods in Cali, with some of the best restaurants, bars and clubs!

Guest favorite
A modern living area features a spacious white table paired with two black chairs. A light-colored sofa provides additional seating. Artistic wall decor complements the neutral color palette, while a large mirror enhances natural light and visual depth in the space.
Apartment in San Antonio
4.85 out of 5 average rating, 65 reviews

Luxury apartment in the Peñon

Luxury apartment located in the exclusive El Peñón neighborhood, the heart of the traditional hotel area of western Cali. Surrounded by a variety of restaurants, bars, nightclubs and cultural areas, close to emblematic sites such as the La Tertulia Museum, the Obelisk, the Cali Zoo, the Cerro de las Tres Cruces, the Gato del Río, the Bulevar del Río, San Antonio and Granada. Perfect for those looking for comfort, style and an unbeatable location to enjoy and explore the city.

Guest favorite
Apartment in San Antonio
4.96 out of 5 average rating, 189 reviews

OM Studio Rooftop at San Antonio - Cali.

Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

Guest favorite
A terrace showcases a spacious seating arrangement under a large umbrella, featuring two stylish chairs and a coffee table. Lush greenery lines the area, while a view of the city skyline and neighboring buildings is visible in the background.
Apartment in Juanambu
4.87 out of 5 average rating, 157 reviews

Exclusive apartment, terrace and private jacuzzi

Para más información, puedes ver más fotos o videos en nuestro IG @bestairbnbcali A 7 minutos del centro de la ciudad encuentras este amplio apartamento con diseño nórdico en la mejor ubicación de la ciudad en el barrio centenario/granada cercano a todos los sitios turísticos, tiene terraza con vistas al oeste de Cali y al cerro de las tres cruces, Jacuzzi privado y pantalla de TV gigante, a una cuadra el mall centenario, cerca de bares y restaurantes.

Guest favorite
Apartment in San Antonio
4.9 out of 5 average rating, 111 reviews

402Studio with balcony in top area + AC and Netflix

Located in El Peñón, one of the safest and quietest neighborhoods in Cali. Steps from the 5-star Dann Carlton Hotel, surrounded by restaurants, bars, nightclubs, casino, museum and park. We have air conditioning, fast WiFi, TV with streaming apps and a free 24/7 laundry area. You can hear the passing of vehicles. Ideal for enjoying the city in comfort and an excellent location. In addition, we offer a clean, cozy environment with quick attention to any need.

Guest favorite
Apartment in San Antonio
4.97 out of 5 average rating, 39 reviews

Apartment close to everything, Peñon, Tina tourist area, A/C

✨ Moderno y acogedor apartamento en el exclusivo barrio el peñon Disfruta caminando el Boulevard del Río, Gato de Tejada, San Antonio, y relajate visitando los mejores restaurantes de Cali, bares y discotecas en la zona. ¡Te esperamos! Nota: Como varios edificios clásicos del Peñón, no tiene ascensor; el acceso es por escaleras. Es ideal para parejas y personas solas que quieren alojarse a pasos de los sitios más emblematicos y divertidos de cali.

Top guest favorite
A modern living space features a cozy seating area with a light blue chair and a gray sofa. A sleek kitchen with barstool seating is highlighted, complemented by contemporary pendant lighting and a stylish backsplash. Natural light fills the room, enhancing the vibrant decor.
Apartment in El Peñol
4.96 out of 5 average rating, 165 reviews

Penthouse Jacuzzi • El Peñón's Best Location

🌴 EXSTR Apartment • Villa del Peñon 401 🫧 Soak in your own open-air jacuzzi on a private terrace in one of Cali’s best locations. This 2-bedroom, 2.5-bath penthouse is perfect for couples, friends, or remote workers. Enjoy A/C, fast Wi-Fi, SmartTVs, a full kitchen, and fresh linens every 4 days. Walk to top restaurants, bars, and San Antonio in minutes. A relaxing, high-comfort stay in the city’s most walkable, cultural neighborhood.

Guest favorite
Home in San Antonio
5 out of 5 average rating, 29 reviews

Colonial house in San Antonio with a spectacular terrace

Enjoy a unique stay in our home located in the iconic neighborhood of Colonia San Antonio, Cali. Our home combines comfort and freshness, and is equipped with everything you may need. Surrounded by a vibrant variety of shops, restaurants, viewpoints, craft market. In addition, the proximity to tourist places will allow you to easily explore our city. Relax in our colonial home and enjoy the best panoramic view from our private terrace.

Top guest favorite
Apartment in Granada
4.94 out of 5 average rating, 86 reviews

°Downtown Gem: Eat, Shop, & Explore on Foot°

Granada 17.22 | Boutique Stays Exclusive 34m² Studio in Granada: Your VIP Pass to Cali Welcome to Granada, the place where culture, flavor, and rhythm collide! This isn't just a studio; it's your VIP pass to the beating heart of Cali. Located on one of the most iconic and happening streets, you'll be so close to the action you can practically smell the amazing food from the best restaurants and cafes just a few steps away.

Popular amenities for San Antonio vacation rentals

  1. Airbnb
  2. Colombia
  3. Valle del Cauca
  4. Cali
  5. San Antonio