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Vacation rentals in San Antonio

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Top-rated vacation rentals in San Antonio

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Guest favorite
A private outdoor jacuzzi is surrounded by lush green plants, adding a natural ambiance to the space. The wooden deck features steps leading to the jacuzzi, complemented by modern lighting fixtures mounted on the wall, enhancing the serene atmosphere.
Apartment in San Antonio
4.99 out of 5 average rating, 73 reviews

Cozy Apartment in El Peñón with Jacuzzi and Gym

★Location, Location, Location.★ Welcome to your spacious home away from home in the heart of Cali! This 1775 sq ft apartment, located in El Peñón, a safe and gastronomic neighborhood, offers everything you need for a comfortable stay. It's just across the street from San Antonio and within walking distance to major city attractions. The apartment features a private patio with gym and jacuzzi, a king-size bed, fully stocked kitchen, safety box, balcony, 250 Mbps WiFi, and two dedicated workspaces

Guest favorite
A staircase with black metal steps leads upward, set against a backdrop of exposed brick wall. Natural light flows through large wooden windows with bars, illuminating a decorative plant in a woven basket and a glass bottle on the floor.
Apartment in San Antonio
4.9 out of 5 average rating, 69 reviews

Cozy+Unique Loft/Touch of Nature/High Speed WiFi

*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

Guest favorite
An open living area features a modern kitchen island with a cooktop, surrounded by wicker chairs and natural light from large panoramic windows. Exposed wooden beams add character to the space, complemented by decorative elements like a wall sculpture and pendant lamps.
Apartment in San Antonio
4.96 out of 5 average rating, 28 reviews

Panoramic Suite Overlooking Colonial Cali

Magical View Suite – Colonial Design in San Antonio Experience the soul of Cali from this cozy suite with an unforgettable view In the historic heart of San Antonio, just steps from Hotel Colina, the space blends colonial charm, local art, and a serene atmosphere designed for rest and inspiration Perfect for travelers seeking history, culture, and gastronomy without giving up modern comforts: a fully equipped kitchen, hot water, reliable Wi-Fi, and a postcard-perfect view from the window

Superhost
A modern living area features a comfortable sectional sofa and an oversized ottoman on a plush area rug. Natural light filters through the window blinds, complemented by warm lighting along the walls. A dining bar with three stylish stools creates a versatile space for meals or work.
Apartment in San Antonio
4.8 out of 5 average rating, 112 reviews

Beautiful apartment in El Peñon

Luxury apartment located in the exclusive El Peñón neighborhood, the heart of the traditional hotel area of western Cali. Surrounded by a variety of restaurants, bars, nightclubs and cultural areas, close to emblematic sites such as the La Tertulia Museum, the Obelisk, the Cali Zoo, the Cerro de las Tres Cruces, the Gato del Río, the Bulevar del Río, San Antonio and Granada. Perfect for those looking for comfort, style and an unbeatable location to enjoy and explore the city.

Top guest favorite
Apartment in San Antonio
4.96 out of 5 average rating, 172 reviews

OM Studio Rooftop at San Antonio - Cali.

Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

Guest favorite
A compact balcony is visible, featuring a round table and a black wicker chair. The vibrant yellow walls provide a bright backdrop, with geometric tile flooring adding texture. Sunlight fills the space, and a view of adjacent buildings and greenery can be seen in the background.
Apartment in Granada
4.9 out of 5 average rating, 102 reviews

59e2 Studio apartment balcony in Granada, Cali

Welcome to CASA RAMBLA SERRA in GRANADA, Cali. This apartment is the perfect place to explore the city, as it is located within walking distance of the main tourist attractions, such as the Museum of Modern Art, the Jorge Isaacs Theater, the Ermita, the Boulevard del Rio, the Plazoleta Jairo Varela and one street from the pink zone full of restaurants, bars, cafes, clubs and shops in Granada. The cat park just 10 minutes away on foot as well as the Peñon, San Antonio

Guest favorite
Apartment in San Antonio
4.91 out of 5 average rating, 101 reviews

401 Charming studio with large balcony + AC and Wi-Fi

Located in El Peñón, one of the safest and quietest neighborhoods in Cali. Steps from the 5-star Dann Carlton Hotel, surrounded by restaurants, bars, nightclubs, casino, museum and park. We have air conditioning, fast WiFi, TV with streaming apps and a free 24/7 laundry area. You can hear the passing of vehicles. Ideal for enjoying the city in comfort and an excellent location. In addition, we offer a clean, cozy environment with quick attention to any need.

Top guest favorite
Apartment in El Peñol
4.96 out of 5 average rating, 163 reviews

Penthouse Jacuzzi • El Peñon's Best Location

🌴 EXSTR APARTMENT • Villa del Peñon 401 Soak in your own open-air jacuzzi on a private terrace in one of Cali’s best locations. This 2-bedroom, 2.5-bath penthouse is perfect for couples, friends, or remote workers. Enjoy A/C, fast Wi-Fi, SmartTVs, a full kitchen, and fresh linens every 4 days. Walk to top restaurants, bars, and San Antonio in minutes. A relaxing, high-comfort stay in the city’s most walkable, cultural neighborhood.

Top guest favorite
A modern apartment interior features a cozy seating area with a dark sofa adorned with red decorative pillows. A compact kitchen is equipped with appliances and a small dining table with red chairs. Natural light streams through sheer curtains, illuminating the wooden flooring.
Apartment in San Antonio
4.92 out of 5 average rating, 142 reviews

Apartment 202 San Antonio

Beautiful furnished apartment in the San Antonio neighborhood of Cali, with its privileged in the tourist sector, you will have access to the best restaurants, parks and theaters in the city in a few minutes. Additionally, the apartment is equipped with everything necessary for you to enjoy a comfortable stay. Don't hesitate to book and enjoy all that Cali has to offer! I'm here to help you with whatever you need!

Guest favorite
A dining area features a white table set with a bowl of fruit, complemented by four beige chairs. Exposed brick walls create a rustic backdrop, while a doorway leads to a well-lit kitchen space with modern amenities. A warm lighting fixture hangs above the table.
Home in San Antonio
4.92 out of 5 average rating, 12 reviews

Traditional house, terrace, views, colonial area

From this house with its traditional charm and all modern comforts in the heart of Cali, you’ll have easy access to everything: supermarkets, tourist attractions, restaurants, art spots, and more. A cozy place to stay for couples, friends, or family. Enjoy the fresh breeze and city views from the spacious terrace. New! Starting December 1, 2025, your stay will include a washing machine – perfect for longer trips.

Guest favorite
An open-plan living space features a dining table with four chairs adjacent to a modern kitchen. A comfortable sofa is positioned nearby, and large sliding glass doors showcase outdoor greenery. Warm lighting creates a cozy atmosphere, complemented by decorative elements like natural fibers.
Apartment in Juanambu
4.93 out of 5 average rating, 120 reviews

IN105 Luxury Oasis | Private Jacuzzi | 350mb WIFI

** EXCLUSIVE UNIT WITHOUT AIRBNB SERVICE FEES ** Welcome to our luxurious loft in Cali, inspired by nature. Measuring 44 m² (474 sq. ft.), with a private outdoor Jacuzzi, and sleeping 2, it is a contemporary oasis. The living room, dining room, and equipped kitchen offer comfort and style. A private bedroom and full bathroom ensure a restful night's sleep. An unbeatable location close to tourist attractions.

Guest favorite
Apartment in San Antonio
4.91 out of 5 average rating, 118 reviews

Exclusive Duplex Apartment

Welcome to our newly renovated duplex apartment in the heart of San Antonio! Embrace the latest design trends in this luxurious space where comfort meets style. Enjoy the vibrant atmosphere of the city right at your doorstep. Feel at home as you indulge in modern amenities and soak in the energy of this bustling neighborhood. Your perfect urban getaway awaits!

Popular amenities for San Antonio vacation rentals

  1. Airbnb
  2. Colombia
  3. Valle del Cauca
  4. Cali
  5. San Antonio