Seneca vacation rentals
Book unique vacation rentals, houses, and more on Airbnb
Top-rated vacation rentals in Seneca
Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Seneca vacation rentals
Other great vacation rentals in Seneca
Treehouse in Walhalla
4.96 out of 5 average rating, 735 reviewsThe Majestic Treehouse romantic, luxury retreat
Dec 18 – 25
Home in Anderson
4.99 out of 5 average rating, 178 reviewsLake Escape
Mar 7 – 14
Guesthouse in Toccoa
4.99 out of 5 average rating, 106 reviewsCozy Rustic Lakefront Cabin
Jul 12 – 19
Condo in Salem
4.95 out of 5 average rating, 107 reviewsBeautiful Lake Keowee Condo with great Amenities
Oct 11 – 18
Place to stay in Townville
4.95 out of 5 average rating, 99 reviewsPeaceful Living Guest House on quiet cove
Nov 8 – 15
Guest suite in Hartwell
4.97 out of 5 average rating, 208 reviewsRelaxing retreat on Lake Hartwell.
Mar 21 – 28
Cabin in Fair Play
4.93 out of 5 average rating, 174 reviewsHartwell Hideaway - Cozy Cabin on Lake Hartwell!
May 29 – Jun 5
Farm stay in Seneca
4.89 out of 5 average rating, 203 reviewsLakeside Cabin ❤ Seneca Treehouse Project
Jan 28 – Feb 4
Seneca house rentals
Home in Pendleton
4.89 out of 5 average rating, 128 reviewsComfort & Convenience Close to Campus
Oct 10 – 17
Home in Clemson
4.85 out of 5 average rating, 186 reviewsAdjacent to Dawson Park/1 mile from Clemson Univ
Sep 4 – 11
Home in Six Mile
4.98 out of 5 average rating, 125 reviewsQuaint country home near Clemson
Jun 20 – 27
Home in Pendleton
4.99 out of 5 average rating, 129 reviews3 BR/2BA Cottage in Pendleton - 9 Miles to Clemson
Nov 15 – 22
Home in Central
4.96 out of 5 average rating, 222 reviewsThe Little House @ Cozy Hollow
Aug 28 – Sep 4
Home in Lavonia
4.99 out of 5 average rating, 112 reviewsThe Willow Lake House
Nov 17 – 24
Home in Seneca
4.99 out of 5 average rating, 169 reviewsLakeside @ Lake Hartwell in Clemson, SC 🐟🌅🚤
Apr 15 – 22
Home in Salem
4.85 out of 5 average rating, 110 reviewsMountains and Lake Area
Oct 8 – 15
Seneca fishing house rentals
Home in West Union
4.95 out of 5 average rating, 137 reviewsSunsets and Siestas -Lake Keowee home near Clemson
Feb 24 – Mar 3
Home in Seneca
4.97 out of 5 average rating, 119 reviewsLake Hartwell house w/ dock 2 miles from Clemson.
Feb 5 – 12
Home in Seneca
4.87 out of 5 average rating, 105 reviewsLake Keowee Home-It's like being in a tree house.
Apr 13 – 20
Home in Anderson
4.95 out of 5 average rating, 141 reviewsLake Hartwell House - Cozy and Close to Clemson!
Oct 21 – 28
Home in Townville
4.94 out of 5 average rating, 151 reviewsZoey’s Cottage on Lake Hartwell w/dock- Secluded
Oct 5 – 12
Home in Easley
4.9 out of 5 average rating, 275 reviews“Lake House Paradise” Waterfront Oasis
Apr 2 – 9
Home in Iva
4.98 out of 5 average rating, 156 reviewsMoonshine Bay
Nov 4 – 11
Home in Seneca
4.85 out of 5 average rating, 174 reviewsCozy Lake House 5 miles from Clemson w Dock
Nov 30 – Dec 7
Quick stats about vacation rentals in Seneca
Total rentals
50 properties
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
1.7K reviews
Nightly prices starting at
ﺩ.ﺇ147 before taxes and fees
Frequently Asked Questions
Are there vacation rentals with a dedicated workspace in Seneca?
Yes! Work meets play with ease at over 20 vacation rentals in Seneca featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there pet-friendly vacation rentals in Seneca?
Four-legged friends are welcome in Seneca. Choose from more than 10 vacation rentals for guests traveling with pets.
How much does it cost to stay in house rentals in Seneca?
Experience the best of Seneca with our house rentals, starting at about $40 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do house rentals in Seneca have a bbq area?
Absolutely! We offer over 10 house rentals with a bbq area in Seneca. Enjoy a tailored experience with all the comforts you desire.
Are there family-friendly house rentals in Seneca?
Seneca has more than 30 family-friendly house rentals. Amenities on the property may include high chairs, travel cribs, or strollers.
Do house rentals in Seneca have wireless internet?
Absolutely! We offer over 30 house rentals with wireless internet in Seneca. Enjoy a tailored experience with all the comforts you desire.
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