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Vacation rentals in Mesilla

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mesilla

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Guesthouse in Las Cruces

4.97 out of 5 average rating, 187 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill. Onsite owners as casita is adjacent to our main home.

Jun 11 – 18

ﺩ.ﺇ304 per night
Guest favorite

Home in Las Cruces

4.95 out of 5 average rating, 239 reviews

Charming 1930 home near NMSU/ Mesilla

Sunny two bedroom one bath house on a quiet tree lined street in Mesilla Park. Enjoy this peaceful retreat close to everything. Conveniently located near the Mesilla Plaza, NMSU, and the Convention Center. Refrigerated air set up on the Nest system. The house has internet access. The wood floors, sash windows and front screen porch give this house the character we fell in love with. We've tried to decorate it to feel like home, and provide all the amenities you might need while you're staying.

Aug 16 – 23

ﺩ.ﺇ439 per night
Guest favorite

Apartment in Las Cruces

4.93 out of 5 average rating, 117 reviews

Enchanted Villas #3

Located 1.4 miles from old town Mesilla on a pecan farm and horse ranch. One bedroom 1 bath apartment, perfect for horse lovers. New furnishings and stainless steel kitchen. Wash your clothes with our "in unit" washer and dryer. No need to worry about laundry detergent and softeners, as these are included in your stay. Grab a drink from the assortment in the fridge. Enjoy the snacks, oatmeal, coffee, tea and soups. We are pet friendly, offer equestrian facilities, and free parking.

Apr 14 – 21

ﺩ.ﺇ283 per night

Popular amenities for Mesilla vacation rentals

Stay near Mesilla's top sights

Mesilla Plaza20 locals recommend
La Posta De Mesilla73 locals recommend
Cracker Barrel Old Country Store4 locals recommend
Andele Restaurant44 locals recommend
Andele's Dog House27 locals recommend
Basilica of San Albino3 locals recommend

Other great vacation rentals in Mesilla

Guest favorite

Townhouse in Mesilla

4.9 out of 5 average rating, 68 reviews

Modern Townhome in Quiet Mesilla

Sep 11 – 18

ﺩ.ﺇ305 per night
Guest favorite

Guesthouse in Las Cruces

4.94 out of 5 average rating, 77 reviews

Casa Elena Adobe casita in historic Mesilla

Aug 29 – Sep 5

ﺩ.ﺇ315 per night
Guest favorite

Guesthouse in Las Cruces

4.94 out of 5 average rating, 86 reviews

Relax in the ❤️ of Old Mesilla. Close to plaza.

Aug 14 – 21

ﺩ.ﺇ385 per night
Guest favorite

Townhouse in Mesilla

4.87 out of 5 average rating, 67 reviews

Heart of Mesilla

Jun 26 – Jul 3

ﺩ.ﺇ324 per night
Guest favorite

Home in Las Cruces

4.91 out of 5 average rating, 22 reviews

Charming Adobe Casita in Old Mesilla - near NMSU

Nov 19 – 26

ﺩ.ﺇ458 per night
Guest favorite

Condo in Las Cruces

5.0 out of 5 average rating, 19 reviews

Sancho's Condo De Mesilla

Feb 3 – 10

ﺩ.ﺇ364 per night
Guest favorite

Home in Las Cruces

4.97 out of 5 average rating, 36 reviews

Cottage Noz

Feb 5 – 12

ﺩ.ﺇ358 per night
Guest favorite

Guesthouse in Las Cruces

5.0 out of 5 average rating, 12 reviews

Cute casita near the university

Jun 3 – 10

ﺩ.ﺇ299 per night
Guest favorite

Apartment in Las Cruces

4.9 out of 5 average rating, 42 reviews

Billy the Kids getaway in Historic Mesilla , N.M.

Oct 27 – Nov 3

ﺩ.ﺇ355 per night
Guest favorite

Guest suite in Las Cruces

4.92 out of 5 average rating, 77 reviews

Southwestern Suite offers Enchanted Experience!

Aug 14 – 21

ﺩ.ﺇ401 per night
Guest favorite

Home in Las Cruces

4.98 out of 5 average rating, 62 reviews

Casa De La Paloma

Apr 28 – May 5

ﺩ.ﺇ598 per night
Guest favorite

Home in Las Cruces

5.0 out of 5 average rating, 24 reviews

Beautiful Farm Home near NMSU

Aug 24 – 31

ﺩ.ﺇ518 per night

Quick stats about vacation rentals in Mesilla

Total rentals

70 properties

Rentals with a pool

20 properties have a pool

Pet-friendly rentals

30 properties allow pets

Family-friendly rentals

40 properties are a good fit for families

Total number of reviews

6.8K reviews

Nightly prices starting at

ﺩ.ﺇ184 before taxes and fees

Frequently Asked Questions

  • Do house rentals in Mesilla have free parking?

    Absolutely! We offer over 20 house rentals with free parking in Mesilla. Enjoy a tailored experience with all the comforts you desire.

  • How much does it cost to stay in condo rentals in Mesilla?

    Experience the best of Mesilla with our condo rentals, starting at about $80 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there pet-friendly vacation rentals in Mesilla?

    Four-legged friends are welcome in Mesilla. Choose from more than 30 vacation rentals for guests traveling with pets.

  • Do house rentals in Mesilla have a kitchen?

    Absolutely! We offer over 20 house rentals with a kitchen in Mesilla. Enjoy a tailored experience with all the comforts you desire.

  • Are there vacation rentals with a dedicated workspace in Mesilla?

    Yes! Work meets play with ease at over 20 vacation rentals in Mesilla featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • What are the most popular amenities for House Rentals in Mesilla?

    Enhance your stay in our House Rentals with the most popular amenities: over 20 homes with air conditioning, over 20 homes with a kitchen, over 20 homes with free parking, over 20 homes with wifi, and more. Indulge in the ultimate retreat, tailored to your preferences.

  • Are there Mesilla vacation rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 20 vacation homes with pools in Mesilla, available on Airbnb. Make a splash and soak up the sun in style!

  • Do condo rentals in Mesilla have air conditioning?

    Absolutely! We offer over 10 condo rentals with air conditioning in Mesilla. Enjoy a tailored experience with all the comforts you desire.

  • Where should I stay in Mesilla?

    Make yourself at home in Mesilla by choosing from our most frequently booked neighborhoods. We have over 520 vacation rentals in Avienda de Mesilla, and over 200 vacation rentals in Mesilla.

  • Are there family-friendly vacation rentals in Mesilla?

    Mesilla has more than 40 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

Destinations to explore

  1. Airbnb
  2. United States
  3. New Mexico
  4. Doña Ana County
  5. Mesilla