Some info has been automatically translated. Show original language

Vacation rentals in Panama City

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Panama City

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Condo in Panama

4.99 out of 5 average rating, 200 reviews

Patty’s Cozy & Quiet Studio with K-bed in Casco

*TOTALLY renovated on NOV 15th 2023: new floors, modern bathroom, new design & art work* Photos to come! Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen beside from the main living space. It is spacious, comfortable and tastefully decorated!

Oct 9 – 16

ﺩ.ﺇ361 per night
Guest favorite

Apartment in Panama City

5.0 out of 5 average rating, 16 reviews

Luxury Mid-Century Apartment In Casco Viejo

Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Sep 24 – Oct 1

ﺩ.ﺇ506 per night
Guest favorite

Apartment in Panamá

5.0 out of 5 average rating, 24 reviews

Amazing experience in Casco Viejo with ocean views

Disfruta la cultura panameña desde el centro de Casco Viejo, donde conocerás la arquitectura colonial, podrás visitar los mejores restaurantes, sitios nocturnos y rooftops característicos de la zona. Apartamento tranquilo y confortable. Cuenta con una cama queen, 1.5 baños, armario, aire acondicionado, cocina equipada, comedor, sala, acceso a WiFi de 500 mbps, espacio de trabajo, balcón y comedor al aire libre. ¡Te ofrecemos todo lo que necesitas para vivir la mejor experiencia local!

Oct 13 – 20

ﺩ.ﺇ385 per night

Popular amenities for Panama City vacation rentals

Stay near Panama City's top sights

Albrook Mall132 locals recommend
Multiplaza Panama147 locals recommend
Causeway Amador67 locals recommend
AltaPlaza Mall38 locals recommend
Atlapa Convention Center15 locals recommend
Sheraton Grand Panama5 locals recommend

Other great vacation rentals in Panama City

Guest favorite

Apartment in Panamá

5.0 out of 5 average rating, 18 reviews

Tropicool Loft w/rooftop steps from Casco

Dec 26 – Jan 2

ﺩ.ﺇ373 per night
Guest favorite

Cottage in Panamá

4.94 out of 5 average rating, 17 reviews

Modern House in Altos de Cerro Azul with 2 rooms

Jun 3 – 10

ﺩ.ﺇ501 per night
Guest favorite

Condo in Panamá

4.94 out of 5 average rating, 71 reviews

CASA SAEMA -PRESTIGIOSO PENTHOUSE DUPLEX WITH TERRACES

Aug 31 – Sep 7

ﺩ.ﺇ1,955 per night
Guest favorite

Condo in Panamá

4.94 out of 5 average rating, 34 reviews

Apartamento en PH Yoo av. Balboa

Feb 26 – Mar 5

ﺩ.ﺇ546 per night
Guest favorite

Apartment in Panamá

5.0 out of 5 average rating, 33 reviews

Full apartment in Panama

Jan 28 – Feb 4

ﺩ.ﺇ285 per night
Superhost

Apartment in Panamá

4.78 out of 5 average rating, 41 reviews

Loft in Casco Viejo

Aug 31 – Sep 7

ﺩ.ﺇ401 per night
Superhost

Apartment in Panamá

4.82 out of 5 average rating, 34 reviews

Exclusive Apartment en yoo panama av balboa

Nov 18 – 25

ﺩ.ﺇ430 per night
Guest favorite

Apartment in Panama City

4.82 out of 5 average rating, 39 reviews

Free bottle Wine -elegant start & Self-check in

Nov 22 – 29

ﺩ.ﺇ316 per night
Guest favorite

Apartment in Panamá

5.0 out of 5 average rating, 41 reviews

City center apartment with pool and ocean view

ﺩ.ﺇ332 per night
Superhost

Apartment in Panamá

4.82 out of 5 average rating, 57 reviews

Ocean Front Apartment in the Best Location

May 31 – Jun 7

ﺩ.ﺇ371 per night
Guest favorite

Condo in Panamá

4.98 out of 5 average rating, 43 reviews

Spacious Executive 37th-Floor Quiet Apartment

Jun 16 – 23

ﺩ.ﺇ463 per night
Superhost

Apartment in Panamá

4.86 out of 5 average rating, 7 reviews

Glimpsy & Tidy - Brand New Place

Jun 28 – Jul 5

ﺩ.ﺇ354 per night

Quick stats about vacation rentals in Panama City

Total rentals

4.2K properties

Rentals with dedicated workspaces

2.3K properties have a dedicated workspace

Rentals with a pool

2.3K properties have a pool

Pet-friendly rentals

1.3K properties allow pets

Family-friendly rentals

1.4K properties are a good fit for families

Total number of reviews

70K reviews

Frequently Asked Questions

  • How is the weather in Panama City?

    Panama City has a tropical climate with high temperatures throughout the year, usually ranging from 75°F to 88°F (24°C to 31°C). Rainy season occurs between May and December, while the dry season extends from January to April.

  • What are some of the best things to do in Panama City?

    Popular activities in Panama City include exploring the historic Casco Viejo district, visiting the Panama Canal Museum, and strolling along the Cinta Costera. Birdwatching in the Metropolitan Natural Park and shopping in the Mercado de Mariscos are also often recommended.

  • What is the best time of year to visit Panama City?

    The most frequented time to visit Panama City is between January and April. This period coincides with Panama's dry season, which enables more comfortable exploration of the city's many attractions. During this time, the vibrant and lively Carnival of Panama, typically held in February, draws a sizable crowd.

  • What are the best places to stay in Panama City?

    Casco Viejo, the city's historic district, is a popular area to stay in Panama City due to its colonial architecture and range of dining options. The modern neighborhood of Punta Paitilla is often recommended for its skyscrapers and shopping centers, while Costa del Este appeals to those seeking a quieter, residential ambiance.

  • What are the best places to visit in Panama City?

    Many visitors to Panama City enjoy the historic district of Casco Viejo, the Panama Canal, and the Metropolitan Natural Park. Other frequently suggested places include the Amador Causeway for its stunning views, and the Biomuseo for its distinct architecture and exhibits on biodiversity.

  • What are some hiking trails in Panama City?

    The Metropolitan Natural Park, located within Panama City, has several hiking trails, such as the Mono Titi Road and the Los Momotides trail. Just outside the city, you can explore the trails of the Soberania National Park, including the Pipeline Road, known for its diverse birdlife.

  • What are some family activities to do in Panama City?

    Families in Panama City often enjoy a visit to the Biomuseo, a museum renowned for its exhibits on biodiversity. The Panama Canal, particularly the Miraflores Locks, provides an educational experience. The Metropolitan Natural Park and Summit Botanical Gardens and Zoo are also popular destinations for families.

  • What are some of the best day trip ideas in Panama City?

    A day trip to the Panama Canal, specifically the Miraflores Locks, is frequently suggested. The beautiful Pearl Islands are also accessible for a day trip from the city. Within the city, exploring the historic district of Casco Viejo, or the biodiversity of the Metropolitan Natural Park, make for enjoyable day trips.

  • Are there family-friendly cottage rentals in Panama City?

    Panama City has more than 10 family-friendly cottage rentals. Amenities on the property may include high chairs, travel cribs, or strollers.

  • How much does it cost to stay in villa rentals in Panama City?

    Experience the best of Panama City with our villa rentals, starting at about $40 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

Destinations to explore

  1. Airbnb
  2. Panama
  3. Panama City