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Vacation rentals in Quartiere San Lorenzo, Rome

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Top-rated vacation rentals in Quartiere San Lorenzo, Rome

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A bright and airy bedroom features a spacious bed with neatly arranged white linens and a decorative throw. Natural light filters through a sheer curtain at the window. A small TV and chair enhance the space, while a pendant light provides warmth.
Condo in Rome
4.94 out of 5 average rating, 252 reviews

Lamperini 79 historic palazzo

A quaint apartment in the San Lorenzo district, renovated with due respect for the building's historical/cultural identity, used as the set of Mario Monicelli's film "I Soliti Ignoti" (Big Deal on Madonna Street). Quiet, yet located in a lively neighborhood full of various bars and restaurants, preserving an authentic, non-touristy nature Connections: bus to the historic center (71 and 492) 20m away, tram 3 to Colosseum and Trastevere and tram 19 to San Pietro, 15 min walk from Roma Termini (metro A and B), very close to La Sapienza University

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Top guest favorite
A cozy living area features a comfortable sofa adorned with patterned cushions. A small table with blue chairs is positioned nearby, complemented by vibrant artwork on the walls. Natural light enters through an open window, creating a welcoming atmosphere.
Condo in Rome
4.94 out of 5 average rating, 181 reviews

central cozy & nice apartment, Rome

Relax in this serene and centrally located space. The apartment, quiet and surrounded by restaurants, supermarkets, and services, enjoys a strategic location just a 15-minute walk from Rome Tiburtina station. Excellent connections to the airports are available via trains and buses. The historic city center is just 6 metro stops away. Equipped with *two bathrooms with showers*, air conditioning, ultra-fast Wi-Fi, and a 36-inch TV, the apartment also provides linens and towels for your convenience

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Top guest favorite
A private garden terrace showcases a mix of colorful chairs and small black tables among flourishing greenery. A shaded area with a slatted roof provides comfort, while a spacious dining table stands ready for gatherings. The tranquil setting invites relaxation and enjoyment.
Condo in Rome
4.97 out of 5 average rating, 112 reviews

Super garden terrace in the heart of Rome

Imagine waking up with breakfast in the sun, a sunset aperitif or a moment of pure relaxation on our garden terrace: a cozy oasis where you can recharge and feel right at home. Let yourself be enveloped by the neighborhood’s authentic and youthful energy, with its traditional flavors, characteristic venues, and exciting atmosphere. In the heart of the city, just a 10-minute walk from Termini and 20 minutes from the Colosseum, to experience Rome with the freedom of having it always within reach.

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Top guest favorite
A spacious living area features a combination of modern and vintage design elements. A comfortable brown sofa and a floral armchair provide seating. A wooden dining table for four stands nearby, while a sleek kitchen is visible in the background with ample cabinetry.
Apartment in Esquilino
5.0 out of 5 average rating, 221 reviews

Independent apartment at San Lorenzo

Independent apartment for up to 4 guests in the authentic and vibrant San Lorenzo district, on the ground floor of a historical building. Fully equipped for the most comfortable stay in Rome — like home, but better. Bedroom with king-size memory foam bed and Smart TV, marble bathroom with washer/dryer, all-electric Miele kitchen, living area with sofa bed and second Smart TV. Free streaming apps and high-speed Wi-Fi. Restaurants, wine bars, shops and public transport all at walking distance.

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Top guest favorite
Condo in Rome
4.95 out of 5 average rating, 101 reviews

Thiago House S. Lorenzo, between Termini and La Sapienza

Stay in the heart of San Lorenzo, one of the most authentic and vibrant neighborhoods in Rome, among street art, culture, history, clubs, and the Roman atmosphere. Just 10 minutes from Termini, Thiago House is the perfect base for exploring the capital, returning each evening to a place that feels like home. Close to the historic Aurelian Walls and the prestigious La Sapienza University, it offers comfort and a great, convenient location for studying, working, or simply enjoying the city.

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Guest favorite
Apartment in Rome
4.78 out of 5 average rating, 138 reviews

Bright apartment Roma Termini San Lorenzo

The apartment is located in the building where Maria Montessori founded her first school. The apartment of about 90 square meters is on the top floor with a beautiful view of the courtyard (with Mediterranean plants and a fantastic jasmine) and the entire area, overlooking Tivoli and the Castelli Romani (Frascati). The San Lorenzo neighborhood is one of the trendiest and liveliest in the city, with numerous restaurants and wine bars. We will be available to our guests during their stay.

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Top guest favorite
Vacation home in Rome
5.0 out of 5 average rating, 24 reviews

The King’s house•Central Rome•5 min from Termini

👑 Welcome to The King’s house — your cozy retreat in the heart of Rome! 👑 Located in the lively and authentic San Lorenzo neighborhood, this elegant apartment offers the perfect blend of comfort and character. Just a short walk from Termini Station, Rome’s main transport hub, it’s ideally positioned to explore the Eternal City with ease. Whether you're a couple, a family with kids, a group of friends, or remote workers, The King’s house is your perfect home base in Rome.

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Superhost
Condo in Rome
4.93 out of 5 average rating, 107 reviews

Quiet Green View Apartment Near Termini

Apartment overlooking the greenery in a central area, within walking distance of the main stations, in a period building. Composed of a spacious double bedroom, a living room with two additional beds in a comfortable sofa bed, an equipped kitchen, and a bathroom with a shower. Air conditioning in the bedroom, bright windows, and a very nice feeling of peace will welcome you upon your arrival at our apartment. National Identification Code: IT058091C2TGK7YYTV

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Guest favorite
The living area features a light wood ceiling with exposed beams, creating an airy feel. A spacious sofa faces a wall-mounted smart TV. A dining table is set with plates and glasses. Large windows allow natural light, complemented by indoor plants for a refreshing touch.
Apartment in Rome
4.94 out of 5 average rating, 120 reviews

Oasi Piceni Apartment San Lorenzo

Oasi Piceni is the ideal place for those who want to live an authentic experience in the Eternal City. Located in the heart of San Lorenzo, a neighborhood rich in history, art and culture, perfectly connected to all places of interest. The apartment is spacious and equipped with all the necessary amenities for a pleasant stay. It has two double bedrooms, a living room with sofa, a fully equipped kitchen and a private terrace.

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Guest favorite
Condo in Rome
4.97 out of 5 average rating, 176 reviews

Apartment in Rome VestiniHouse

Cozy independent apartment with double bedroom that can be converted into two single beds with the possibility of an additional bed for a child or teenager. A kitchen equipped with every comfort: a set of dishes, glasses, pots, kettle, induction hob, refrigerator, microwave, and espresso machine for pleasant relaxation. The accommodation has air conditioning to cool the rooms in summer and heating for winter and fast wifi.

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Top guest favorite
Apartment in Rome
4.94 out of 5 average rating, 83 reviews

Bright penthouse with terrace

Our house is in the central district of San Lorenzo in Rome. It is located on the 4th floor of a building equipped with an elevator. It is perfect for 4 people as there is a double bedroom and one with two single beds. We enjoy an unobstructed view and incredible light, and from the house you can access the private upper terrace equipped for dining or just relaxing and enjoying the rooftops of Rome.

LocationFamilyHospitality

Top guest favorite
A bright studio space features a spacious bed with light bedding and decorative pillows. A vintage-style wardrobe and a comfortable armchair are visible, alongside a patterned sofa. Large windows draped with soft curtains allow ample natural light to fill the room.
Apartment in Rome
5.0 out of 5 average rating, 22 reviews

BoHo Studio & Terrace

Bohemian studio in the heart of San Lorenzo. Bright and quiet environment with all the comforts for travelers. Two bedrooms, a kitchen with a peninsula and a large internal terrace make it the perfect spot to relax and plan your Roman stay. Close to major attractions, the lively San Lorenzo neighborhood is well-connected, near Tiburtina and Termini stations, and rich in typical restaurants and bars.

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