Vacation rentals in Perry County

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Top-rated vacation rentals in Perry County

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Loft in Perryville

4.98 out of 5 average rating, 265 reviews

Downtown Loft Amazing Bath Tub & Shower

Downtown Perryville, MO **DISCLAIMER** you will hear restaurant chatter & music if you do not have a tv/or radio playing between the hours of 10:30am & 1:30am. If you go to bed early I recommend headphones, ear plugs or play nature sounds on Alexa. This is a pet friendly loft apartment so I would not recommend if you are allergic to dogs or cats. This apartment is located above one of the most popular destination restaurant's around "Mary Jane Burgers & Brew" on the Downtown Historic Square.

Oct 24 – 31

ﺩ.ﺇ511 per night
Guest favorite

Farm stay in Frohna

4.98 out of 5 average rating, 103 reviews

The Weber Farm - Enjoy a beautiful 100 acre farm!

Enjoy a 125+ year old country home with large yard and beautiful shade trees located on a 100-acre farm in the rolling hills of SE Missouri. The house is very clean and spacious with 4 large bedrooms, comfortable beds, beautiful hardwood floors and a large living room. We have hand-made quilts and antique furniture throughout. The kitchen is fully furnished. Relax on our 40’ front porch with swing, by the fire pit or in a hammock. A perfect place for you to recharge from stress & busy schedules!

Sep 15 – 22

ﺩ.ﺇ527 per night
Guest favorite

Dome in Perryville

4.93 out of 5 average rating, 80 reviews

Off Grid DOME Glamp *Snow Globe*: Adventurers Only

EXPERIENCE The Snow Globe in the Woods • IMMERSE in complete silence with the absence of electricity: no hum or vibrations from this completely solar/propane fueled geodesic dome • GLAMP in this OFF GRID ADVENTURE. 430 sq ft floor plan. 14 ft ceiling. 20 ft bay window with endless nature view at the foot of your bed. Lofted 7ft. • STARGAZE from the deck or fire pit • NESTLE in the romantic wooded nature of southeast MO. S of St Louis.N of Memphis • UNPLUG, UNWIND, RELAX. Adventure seekers only!

Feb 13 – 20

ﺩ.ﺇ532 per night

Popular amenities for Perry County vacation rentals

Other great vacation rentals in Perry County

Guest favorite

Home in Union Township

4.94 out of 5 average rating, 70 reviews

Charming countryside getaway!

Mar 7 – 14

ﺩ.ﺇ369 per night
Superhost

Farm stay in Perryville

4.92 out of 5 average rating, 13 reviews

The Farmhouse by Grandma Bea’s

Dec 9 – 16

ﺩ.ﺇ702 per night
Guest favorite

Home in Perryville

4.98 out of 5 average rating, 64 reviews

17 Acre Lake Retreat - Cash Lodge

Jun 21 – 28

ﺩ.ﺇ761 per night
Superhost

Home in Saint Mary

4.73 out of 5 average rating, 11 reviews

Ste. Genevieve Co. House w/ HOT TUB!

Jun 10 – 17

ﺩ.ﺇ598 per night

Guest suite in Perryville

4.8 out of 5 average rating, 114 reviews

Oma's Place

Aug 24 – 31

ﺩ.ﺇ428 per night
Guest favorite

Home in Perryville

5.0 out of 5 average rating, 6 reviews

Brewer House

May 28 – Jun 4

ﺩ.ﺇ413 per night
Guest favorite

Home in Perryville

5.0 out of 5 average rating, 6 reviews

German-Inspired Home in Perryville

Apr 17 – 24

ﺩ.ﺇ348 per night
Guest favorite

Home in Altenburg

5.0 out of 5 average rating, 5 reviews

Gem in Heart of Altenburg

Jan 31 – Feb 7

ﺩ.ﺇ649 per night
Guest favorite

Home in Ste. Genevieve

5.0 out of 5 average rating, 24 reviews

Secluded Cabin with Heated Pool, hot tub, fireplac

Feb 18 – 25

ﺩ.ﺇ4,059 per night
Guest favorite

Home in Ava

5.0 out of 5 average rating, 20 reviews

Paradise Ridge in the Shawnee National Forest

Jul 30 – Aug 6

ﺩ.ﺇ629 per night

Home in Perryville

5.0 out of 5 average rating, 3 reviews

'The Brewer Guesthouse' Tiny Home w/ Patio & Yard!

Jan 6 – 13

ﺩ.ﺇ486 per night

Apartment in Old Appleton

New place to stay

Apple Creek Loft

Feb 16 – 23

ﺩ.ﺇ377 per night
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