Vacation rentals in Osborn Medical Center, Phoenix

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Top-rated vacation rentals in Osborn Medical Center, Phoenix

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A historic guesthouse is framed by a mix of stone and soft greenery. The outdoor area features a stone pathway, bordered by low shrubs, leading to a covered seating area under a wooden gazebo. Sunlight fills the scene, highlighting the inviting residence.
Guesthouse in Encanto
4.97 out of 5 average rating, 207 reviews

Best Little Guesthouse in Melrose !

Historic guesthouse in the heart of the Melrose District! EV charger! Walking distance to restaurants, bars, coffee shops, the famous Melrose Vintage shops, grocery stores, LA Fitness and more! Want to head downtown to Chase Field, Talking Stick Arena for a game or a show? Campbell Street Light Rail station is only five short blocks away! No need for a car, you can take the Light Rail from Sky Harbor International Airport, save your money for entertainment! Off street parking if you have a car!

Top guest favorite
The angular architecture of the mid-century modern house is highlighted against a clear blue sky. Large windows framed in wood offer panoramic views, while the stony exterior and natural landscaping present a harmonious blend with the mountainside setting.
Guest suite in Phoenix
4.98 out of 5 average rating, 449 reviews

Views & Architecture-Mid Century on Mountain

This spectacular mid century modern house is nestled in the Phoenix Mountain Parks Preserve on Shaw Butte. Designed by celebrated architect Paul Christian Yeager, this magnificent home has Frank Lloyd Wright influences throughout. The top floor is yours to enjoy, with its own private entrance, kitchenette with refrigerator, microwave, coffee pot, sunken bathtub, comfortable beds, and mountain and downtown Phoenix views. Celebrate your special occasion here!Permit STR-2024-001528, TPT #21148058.

Top guest favorite
Guesthouse in Phoenix
4.98 out of 5 average rating, 250 reviews

Your favorite PHX guesthouse!

Enjoy your stay in this cozy backyard casita, newly remodeled (320 sq. ft.) and complete with full kitchen & bath. Fully enclosed backyard perfect for the pups! Conveniently located off of the Camelback corridor, central to all of Phoenix metro. You'll be close to the airport, restaurants, coffee shops, grocery and entertainment. Within walking distance to the canal for your morning or evening workout. Sleeps 2 people. *All guests must be listed in reservation. Registered guests only*

Superhost
A welcoming living area features two brown leather sofas positioned around a vibrant area rug. A coffee table is centered between them, and a television is mounted on a green accent wall. A potted plant adds a touch of greenery, enhancing the space's warmth.
Condo in Encanto
4.88 out of 5 average rating, 182 reviews

The Beverly Bungalow 1BR/BA in the 🖤 of Phoenix

Relax & unwind at our mid-century bungalow in the heart of Phoenix. This 1BR/1BA condo will comfortably sleep 2 (up to 4 using an air mattress). Our condo is complete with a full kitchen, cozy living room & dedicated work space for the WFH professional. Also included is a shared pool/hot tub to cool off on those hot summer days. Located in Midtown center to museums, unique bar & restaurant concepts, Chase Field, The Footprint Center - the list goes on. We hope you enjoy all AZ has to offer!

Guest favorite
A bright yellow adobe casita stands amidst a lush garden, featuring a blue door and several windows. The structure includes a second-floor balcony, complemented by a patio area with wooden seating. Various plants and trees enhance the tranquil outdoor setting.
Cottage in Encanto
4.9 out of 5 average rating, 162 reviews

Stunning Historic Adobe in Central Phoenix!

Beautiful, bright, airy, mid-century adobe casita, located and overlooking a walled tropical garden in historic central Phoenix. 10 min from Sky Harbor Airport and located in the very popular and historic Melrose District. 20 restaurants, bars, cafes within 3 blocks walking distance. Wine shops, vintage stores, grocery, and pharmacy within 2 blocks walk. Scottsdale/Downtown Phoenix a very short drive. Furnished with antiques and regional artwork. Wifi, TV, full kitchen, washer/dryer included.

Guest favorite
The pool area is surrounded by lush tropical landscaping, with shaded seating nearby. Sunshades provide protection from the sun over the shimmering water, creating a serene atmosphere. Natural stones and greenery enhance the tranquil setting, inviting relaxation and enjoyment.
Place to stay in Phoenix
4.96 out of 5 average rating, 1,055 reviews

Guest House 1 King Bed Pool/Jacuzzi/urban Phoenix

“CHECKING IN INSTRUCTIONS”at “GUEST RESOURCES”on Airbnb. PLEASE NO EARLY CHECK-IN due to time constraints. The guest room air conditioner/heater/king size bed/linens/Plates/glasses-all plastic, towels/wifi/premium cable with movies Premium internet. Guest house 275 sq feet There is street parking with parking permit available. Alwa NO SMOKING of any products inside guest house Property 420 friendly only in outdoor spaces QUIET HOURS between 10:00 pm-5:00 am pool/hot tub close 10:00pm

Guest favorite
The exterior of a charming studio guesthouse is visible, showcasing a brown brick facade and a well-kept entrance. A small pathway leads to the door, and palm trees can be seen in the background against a bright blue sky.
Guesthouse in Phoenix College
4.97 out of 5 average rating, 1,275 reviews

Private, Sparkling Clean Historic DTPHX Guesthouse

This charming studio guesthouse in the Campus Vista historic district is a fantastic find! Situated in a friendly neighborhood in the heart of Phoenix, this newly remodeled living space is cozy and practical, surpassing many of the similar properties in quality and character. A short ten-minute drive from the Sky Harbor Airport, and located within walking distance to two major bus lines and the light rail, the guests are sure to enjoy the easy access to all the popular downtown destinations.

Top guest favorite
A cozy bedroom featuring a spacious bed with a custom leather headboard. A large black and white mural of cacti adds character to the room. A modern pendant light hangs above, complementing the warm tones of the wooden bed frame and the textured beige bedding.
Guest suite in Encanto
4.99 out of 5 average rating, 369 reviews

Private, desert-chic casita in vibrant Midtown PHX

Welcome to Casita Amelia, a modern rustic retreat central to all the action Phoenix has to offer. Welcoming and cozy, this newly updated private guest suite has all the luxuries of a modern hotel suite while being quietly tucked away in a cute Midtown neighborhood. Walk to Melrose District. You're also just 5-10 mins by car to Uptown & Camelback Corridor, 10 mins to Downtown (Footprint Center, Chase Field, Arizona Financial), 15 mins to Sky Harbor Airport, and 20 mins to State Farm Stadium.

Top guest favorite
A communal living space features a comfortable sofa adorned with various textured cushions. A chalkboard wall displays creative messages, while a vibrant red kitchen cabinet adds visual interest. Sunlight enters through double French doors, enhancing the overall ambiance.
Guesthouse in Encanto
5 out of 5 average rating, 360 reviews

Urban Green House The Garden House

The Urban Green House brings farm life to the urban core. We offer fresh eggs from our backyard hens and gardens for guests to enjoy. We also live green-using solar panels, recycling, and composting. Sarah and Ryan live locally and are available to meet any needs that arise. We are located in a quiet and safe 1950s neighborhood, close to local restaurants, coffee shops, Encanto park, direct access to both the I-10 and I-17 freeways, and only 8 miles from Phoenix Sky Harbor Airport.

Guest favorite
A spacious backyard features a green lawn and raised garden beds. A cozy seating area with red chairs is positioned near the house, while palm trees provide shade. Fencing surrounds the area, ensuring privacy and creating a serene outdoor space.
Guesthouse in Encanto
4.9 out of 5 average rating, 388 reviews

Amazing Central Phoenix Guest House

Beautifully updated guest house with polished concrete floors, renovated bathroom, and new kitchen that includes a gas range. Enjoy free wifi and 70 inch 4K TV with netflix, hulu, pandora, and spotify Centrally located near downtown Phoenix. Close to encanto park, encanto golf course, phoenix college, several hospitals and endless dining and entertainment options. Not a far UBER ride to the airport, sports arenas, zoo, spring training. close to light rail, GRID bike share program.

Top guest favorite
A cozy studio space is featured, showcasing a queen bed with plush pillows and a decorative headboard. A small dining area with elegant plates is positioned nearby, complemented by a kitchenette stocked with essential items. Light fixtures add a subtle ambiance to the room.
Guesthouse in Encanto
4.91 out of 5 average rating, 318 reviews

Converted 30s Historic Carriage House in Del Norte

Reliably operated by a top AZ Superhost with 4,200+ 5 star stays. Del Norte - the only historic district near downtown Phoenix to be surrounded by 3 green parks. This is a converted 1930’s carriage house (next to an English Revival Cottage) that was carefully curated with your rest and peace in mind. Exclusive designer finishes, with full functionality - fully stocked mini-kitchen, spa like bathroom. Patio seating in the shade to enjoy the AZ inside / outside living.

Top guest favorite
A single-story guest house is presented with a red front door and a comfortable white bench against a light gray exterior. The surrounding area features a paved stone patio and is complemented by lush greenery and palm trees in the background.
Guesthouse in Encanto
5 out of 5 average rating, 160 reviews

Desirable Melrose District Guesthouse

We welcome you to enjoy our private guest house in the historic Yaple Park neighborhood of uptown Phoenix and the celebrated Melrose District with multiple bars, restaurants and vintage shops all within easy walking distance. We are only a few blocks from the light rail which will get you downtown, Sky Harbor Airport, Tempe or Mesa. “This property can’t be used for purposes identified in A.R.S. 9-500.39." Phoenix Short-Term Operating Permit No: STR-2023-000371.

Popular amenities for Osborn Medical Center, Phoenix vacation rentals