
Boutique hotels in Middlesex County
Find and book unique boutique hotels on Airbnb
Top-rated boutique hotels in Middlesex County
Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

Orchard Room: The Inn at Fireside Tavern Sherborn
The perfect blend of New England charm and modern boutique luxury, The Inn at Fireside Tavern Sherborn offers 4 private suites, thoughtfully designed around unique local characteristics. Located in the heart of Sherborn, our guest rooms sit directly above our vibrant community tavern, providing a sophisticated and convenient haven for your stay. Whether here for a wedding, local getaway, or peaceful one-night stay, you’ll find a seamless connection between upscale comfort and exceptional dining.

Longwood Area | Perfect for Long Stays & Visits
Stay in a charming 1886 Victorian home in the heart of Brookline, Boston. Perfect for long stays, with cozy parlors and timeless charm. 🏡 Location & Accessibility Public Transport Nearby: Just a block from Saint Mary's Street Station, offering easy access to downtown Boston and surrounding areas. Restaurants & Local Shops: The vibrant Coolidge Corner neighborhood is only about 1 mile. Museums & Cultural Attractions: Fenway Park, Boston’s iconic baseball stadium, is about 1.2 miles away.

JD Hotel “Blue Lagoon”
Welcome to the new opening of the JD hotel! Full service fine art boutique hotel! Queen size temperpedic, massage chair,cedar closet ,new tv with Roku, Netflix’s starz’s and Wi-Fi!!Front hall kitchen area when you first walk in is equipped with everything! There’s also a mini fridge in the room and a private shower room attached to the room! Right near the Worcester airport! Free laundry and dish service.The bus stop is right outside! 🏳️🌈 very clean loft! All the art is for sale.

Prime Location! Unit w/ Parking, Pet-friendly!
Just minutes from the hustle and bustle of downtown Boston, this property offers a convenient, budget-friendly stay in the Boston area. Head to the nearby Stone Zoo or the Liberty Ride Trolley Tour for a fun day with the family. If you’re visiting the area for a campus visit, MIT, Harvard, Tufts, Boston University, and several other schools are just minutes away. Close to all the action, but away from the crowds, this property is a great choice for your Boston area getaway!

(SG) Bright, cozy room with two beds, shared bath
Blending modern conveniences with historic charm in this 1867 Victorian-style house, this guest room has one full size bed and a single bed. In addition, the room can be booked together adjacent guest room for a larger group up to 4 people. If booked together, the combined ensuite is consisted of two bedrooms, with the private bathroom located in the larger guest room. Located just 7 minutes from the Red Line T, we are at the heart of Cambridge between Harvard and MIT.

Deluxe Queen at Ginkgo House
This sun-filled large bedroom is situated on the second floor our large Victorian-style house. It has four large windows with ample natural light and a view of our lovely ginkgo trees in the front. The room has one queen bed, and two twin beds for a perfect family stay up to four people, two adults and two children. This centrally situated house is only 7 minute walk from the red line subway station, 10 minute walk to Harvard, and a WholeFoods within 5 minute walk.

Prentiss House by Thatch | King Rm #15
Prentiss House by Thatch is a 20-room boutique hotel nestled between Harvard and Porter Square in an iconic Cambridge neighborhood setting. Built in 1843 and renovated in 2022, the building's rich architecture is complimented by modern amenities and fresh design, providing an upscale yet laid-back atmosphere. Using state of the art technology, roaming staff and a virtual front desk, most guests enjoy their stay without ever needing assistance from our staff.

Boutique Hotel Room - Charlesmark Hotel
Originally built in 1886 as a private residence in the heart of Boston's Back Bay neighborhood, the hotel has been completely renovated. Our European style boutique hotel features a hip cocktail lounge with an outdoor patio. (Lounge currently unavailable) Premier location. Exceptional value. European ambiance. The Charlesmark combines it all to create a memorable lodging experience. Ambiance - Genuine, Intimate Service

Family Queen at Ginkgo House
Welcome to the Ginkgo House, a Victorian era house built in 1867 with modern amenities. This is a simply decorated family-style room located on the third floor of the house with private bathroom consist of one queen size bed, two singe beds, a study desk, and a mini fridge. Plenty of lights with three windows and a skylight. Shared common areas include living room, dining room, and kitchen; high speed WiFi.

The Whitney Boston, Classic Double Queen
The newly-opened Whitney rocks a classic brick townhouse vibe in lovely Beacon Hill, with thoughtful perks like house bikes and a Mediterranean-inspired restaurant, starring creative, seasonally-driven menus. Your room charge will be paid prior to your arrival. The remaining balance of taxes (14.95%) will be charged upon arrival. A refundable security deposit of $XX will also be collected.

Harborside Inn-Boutique Hotel
Originally built in 1846 as a mercantile shipping warehouse on the Boston Harbor. Here, a modern design with a nautical theme is accented with the latest high technology amenities to satisfy the most savvy business or leisure traveler. Premier location. Exceptional value. Stylish decor. The Harborside Inn combines it all to create a unique lodging experience.

Welcoming Room in the Heart of Boston's History
Explore historic Boston from our ideal location in Back Bay. Enjoy nearby elite shopping, fine dining, and arts, with the Boston Common and Public Garden close by. The charm of Beacon Hill and the buzz of the Theater District are just a short walk away. All major landmarks, including the Freedom Trail, are less than a mile from our doorstep.
Popular amenities for Middlesex County boutique hotels
Family-friendly boutique hotels

Prentiss House - Family Suite | King & Queen

ADA Copley Queen - Copley Square Hotel

Living the Boston Dream! Pets are Also Welcome!

Getaway with Friends! 3 Units Close to Downtown!

Cambridge Stay Near Tufts University-Pet Friendly!

A Boutique Hotel Room in Copley, Charlesmark Hotel

Boston Adventure! 3 Units Close to Downtown Boston

Minutes to Commuter Rail! Free Parking Onsite!
Boutique hotels with a patio

Prentiss House by Thatch | King Room #10

Prentiss House by Thatch | Deluxe King #17

Prentiss House by Thatch | King Suite #4

Prentiss House by Thatch | King Rm #14

Prentiss House by Thatch | King Rm #20

Prentiss House by Thatch | King Deluxe #6

Prentiss House by Thatch | Queen Rm #19

Prentiss House by Thatch | Deluxe King #1
Other boutique hotel vacation rentals

Comfort & Convenience! 2 Units w/ Free Parking!

2 Units Near Woburn Mall! With FREE Parking!

Copley King - Copley Square Hotel

Ideal for Business Travel! 3 Units w/ Free Parking

Easy Highway Access! 3 Units Near Downtown!

Two Pet-friendly Units with Free Parking Onsite!

Prentiss House by Thatch | Deluxe King Rm #18

Boston Getaway! 2 Convenient Units, FREE Parking!
Destinations to explore
- Bed and breakfasts Middlesex County
- Rentals with a kayak Middlesex County
- Smoking-friendly rentals Middlesex County
- Beachfront rentals Middlesex County
- Rentals with an accessible height bed Middlesex County
- Rentals with breakfast Middlesex County
- Apartment rentals Middlesex County
- Hotel rooms Middlesex County
- Rentals with a fireplace Middlesex County
- Rentals with beach access Middlesex County
- Rentals with an accessible height toilet Middlesex County
- Private suite rentals Middlesex County
- Pet-friendly rentals Middlesex County
- Rentals with a patio Middlesex County
- Rentals with a home theater Middlesex County
- Rentals with a hot tub Middlesex County
- Rentals with an EV charger Middlesex County
- Rentals with a fire pit Middlesex County
- Townhouse rentals Middlesex County
- Loft rentals Middlesex County
- Rentals with pools Middlesex County
- Rentals with outdoor seating Middlesex County
- Waterfront rentals Middlesex County
- Family-friendly rentals Middlesex County
- Guesthouse rentals Middlesex County
- Cottage rentals Middlesex County
- Rentals with lake access Middlesex County
- House rentals Middlesex County
- Condo rentals Middlesex County
- Serviced apartment rentals Middlesex County
- Rentals with a washer and dryer Middlesex County
- Fitness-friendly rentals Middlesex County
- Boutique hotels Massachusetts
- Boutique hotels United States
- Hampton Beach
- Fenway Park
- TD Garden
- Harvard University
- Boston Common
- Brown University
- Revere Beach
- Boston Seaport
- Boston University
- Freedom Trail
- New England Aquarium
- MIT Museum
- Boston Convention and Exhibition Center
- Monadnock State Park
- Canobie Lake Park
- Gillette Stadium
- Crane Beach
- Duxbury Beach
- Quincy Market
- Museum of Fine Arts
- North Hampton Beach
- Roxbury Crossing Station
- Prudential Center
- Roger Williams Park Zoo
- Things to do Middlesex County
- Food and drink Middlesex County
- Art and culture Middlesex County
- Sightseeing Middlesex County
- Things to do Massachusetts
- Sightseeing Massachusetts
- Art and culture Massachusetts
- Nature and outdoors Massachusetts
- Food and drink Massachusetts
- Things to do United States
- Sports activities United States
- Art and culture United States
- Wellness United States
- Sightseeing United States
- Entertainment United States
- Food and drink United States
- Tours United States
- Nature and outdoors United States




