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Vacation rentals in Lake Nona

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Lake Nona

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
The villa features a distinct architectural style with a terracotta roof and a landscaped front yard. Lush palm trees are positioned around the entrance, while a spacious driveway leads to a three-car garage, all set against a tranquil evening sky.
Villa in Kissimmee
5 out of 5 average rating, 119 reviews

Villa Sol Peaceful Pool/Hot tub Home

Close to all major attractions, and airport sits this private villa. It has a little something for all ages! Your family can play in the pool or relax in the hot tub. Enjoy fun game nights with a cabinet full of games, or play a game of basketball, pickleball, or tennis right outside our pool. Fun on the playground or enjoy the clubhouse gym. All of your needs for the beach trips or the ball games. All of your baby's needs are covered as well. Ask about Stroller and cart rentals. We have it all

Top guest favorite
A modern living space blends comfort and style, featuring a plush sectional sofa with decorative pillows and a sleek coffee table. A large flat-screen TV is mounted on the wall, and natural light streams through expansive windows. An open layout connects the living area to the kitchen-dining space.
Home in Orlando
4.99 out of 5 average rating, 68 reviews

Beautifully Renovated, Centrally Located Pool Home

Discover Orlando from this beautifully remodeled home, perfectly located near Disney, Universal Studios, downtown, and prime shopping. Enjoy the serene private pool with stunning day and night lighting. The home features three stylish bedrooms with private TVs, two modern bathrooms, and a cozy fireplace with a dedicated seating area. Offering a blend of comfort and convenience, this home is your ideal base for an unforgettable Orlando experience. Book your stay to create unforgettable memories!

Guest favorite
A cozy living area features a leather sofa and a plush ottoman at its center. A large TV is mounted on a dark wooden unit against a wall adorned with botanical artwork. Natural light filters through the windows, complemented by light curtains and a decorative wall mirror.
Cottage in Orlando
4.96 out of 5 average rating, 78 reviews

Cozy Guesthouse w/ Outdoor Oasis

Kick back & relax in this cozy, private guesthouse featuring a fenced outdoor space with covered seating, electric grill, yard games & a fire pit. The guesthouse includes a king-size bed, full kitchen, laundry, 2 smart TVs & ample parking for your boat Located just 3.5 miles from Moss Park, where you can enjoy fishing, boating, wildlife, walks, & playground. Close to Lake Nona, Orlando Airport, & the USTA campus. Easy access to highways, with most Orlando attractions within a 40-minute drive.

Guest favorite
A screened-in patio features a heated pool surrounded by concrete flooring. Colorful inflatables are present in the water, with a rainbow umbrella positioned nearby. Lush greenery and residential buildings are visible in the background under a clear blue sky.
Home in Kissimmee
4.87 out of 5 average rating, 114 reviews

New Listing! Casita Bonita Pool House

Bring the whole family to this great place with lots of room for fun. Beautiful house in Kissimmee. Perfect home to relax and enjoy quality time with the family. Airport (Orlando International): 15 - 20 Minutes Lake Nona 10-12 Min Taking a cruise? 🚢 Port Cañaveral 45min Disney Springs: 25 - 30 Min Disney's Magic Kingdom & Disney's parks:35-45Min Florida Mall: 20 - 25 Min Islands of Adventure: 25 - 30 Min Premium Outlets (Vineland Ave): 20 - 25 Min Universal Studios & Volcano Bay 25 - 30 Min

Top guest favorite
A bright and spacious area features a white bed and a stylish brown sofa. Modern decor is complemented by natural elements, including a potted plant. A wall-mounted television and a wooden coffee table enhance the inviting environment.
Guest suite in Kissimmee
4.94 out of 5 average rating, 211 reviews

temple & A/C glamping under a 120 y/o oak tree

How this Airbnb was born? We wanted to create a space to enhanced our soul, power our mind, fuel ourselves, to meditate, to create ideas, to be a part from the world, The Temple. Glamorous Camping idea came across, oh my!, once you go inside this tent, you don't want to come out. Be present. Friends and family started asking, can I stayed?, day by day closer people want it to live this experience and more positive comments we were getting, so we decided, why don't let others try it? Welcome

Guest favorite
A modern living space is highlighted by a plush grey sofa and mid-century styled furniture. A large window invites natural light, showcasing views of the outdoors. Decorative elements, including a small plant and artwork, add character to the room while maintaining a clean aesthetic.
Loft in Colonialtown South
4.92 out of 5 average rating, 623 reviews

Contemporary Loft Near Downtown

Conveniently located between the foodie-friendly Milk District and Downtown Orlando, this impeccably thought-out space features a spacious loft style open floor plan perfect for a couple or small group. The floor to ceiling windows allow natural light to fill the space while providing complete privacy during your stay. Upscale Winter Park restaurants and the vibrant Thornton Park art scene are only a short drive away. Universal is only 20 minutes away, Disney is 35 minutes, MCO 20 minutes.

Top guest favorite
A spacious living area is displayed, featuring a sectional sofa and a large wall-mounted TV. The open kitchen showcases modern appliances and a dining table for six. Natural light floods the space through sliding glass doors that lead to the backyard.
Home in Orlando
4.97 out of 5 average rating, 148 reviews

Beautiful House Completely Remodeled

Forget your worries in this spacious and serene space. Completely remodeled, everything is brand new. You will love to stay at this beautiful house come and see for yourself! Only 10 minutes away from the airport. 15 minutes away from UCF. 20 minutes from SeaWorld and Aquatica. 30 minutes from Universal Studios, Island of Adventure and Volcano Bay. 30 minutes from Disney World. 10 minutes from Lake Nona. 15 minutes from Down Town. 25 minutes to the Outlets. 15 minutes to Kia Center.

Top guest favorite
A treehouse is illuminated by warm string lights, nestled among large branches under a deep blue sky. The structure features large windows allowing views of the surrounding greenery, with a cozy seating area visible inside. A wooden walkway leads to the entrance.
Treehouse in St. Cloud
4.96 out of 5 average rating, 1,051 reviews

TreeHouse in the Cloud, (Close toTheme Parks

The treehouse is a private getaway for a couple that want to experience the magic. Check out video tours on U-Tube. Type in Treehouse in the Cloud. There have been several movie and other photo shoots done on property. Please text request and details, and we can negotiate fees. Our other AirBnB is just next door; Country gem horses close to Theme parks [link] Which is 1,000 sq ft and sleeps six.

Top guest favorite
A white door is adorned with a decorative wreath featuring white flowers and greenery. Adjacent to the door, a wooden sign with a rustic finish displays the word 'HOME' in large, bold letters, creating a welcoming entryway.
Apartment in Orange County
4.9 out of 5 average rating, 280 reviews

Lake Nona / Comfy Corner

We have a very comfortable place , centric location , close to any activity or necessity for our guests. One but not least, USTA Tennis Campus , DisneWorld, Universal Studios, Sea World, Aquatica, Children Hospital,Veteran Hospital, Restaurants, Parks, Theme Parks, Waterparks, MCO International Airport only 10 min Downtown Orlando, Florida Mall, last but not least Millennium Mall, Cocoa Beach, Tampa, Kennedy Space Center and way more! Just a drive away.,

Guest favorite
A spacious living area is featured, highlighted by a large sectional sofa and a glass coffee table at the center. Natural light fills the room through multiple windows, illuminating the neutral-colored walls and decorative accents. A dining area is visible in the background, complete with stylish seating.
Townhouse in Kissimmee
4.9 out of 5 average rating, 124 reviews

Fully equipped house 5 beds, 7 people, near parks

New house, is a family home decorated with the best furnitures, to be a great experience to spend a family time. You can park your car on the street in front of the main door. The garage is closed whit my cars inside. Beautiful common spaces, whith pool, GYM, basketball and tennis courts, Kids playgroud. Beautiful common spaces, with pool, basketball and tennis courts. Kids playground Security access gate to visitors and residents

Top guest favorite
A modern communal game room features a sleek pool table prominently positioned. Stylish pendant lights hang above, highlighting the elegant bar area with high-backed stools. Large windows provide ample natural light and showcase views of the outdoor landscape, creating an inviting and social atmosphere.
Apartment in Orlando
4.98 out of 5 average rating, 51 reviews

Stylish King Apt, Close to Disney & Pet-Friendly

Welcome to our Modern 1-Bedroom, 1-Bathroom Apartment in Orlando! This chic and cozy apartment offers the ideal base for your Florida adventure. It combines comfort with convenience, featuring easy access to nearby theme parks, shopping, and dining options. Relax with resort-style amenities in the charming community. The whole apartment will be yours and NOT shared. Please reach out for potential multi-day discounts.

Top guest favorite
The tranquil scene captures a lakeside view framed by trees at dusk. The horizon glows with soft orange and yellow hues, reflecting on the water. A hammock is visible, adding to the serene atmosphere of the wetlands beyond.
Guest suite in St. Cloud
4.94 out of 5 average rating, 396 reviews

LAKE FRONT Suite w FREE Kayaking/Canoe

Private Master Suite with it's own exclusive entry. It has a convenient kitchenette complete with mini refrigerator, microwave, toaster, toaster oven and an outside grill. Comfy Queen size bed with overhead ceiling fan. Private Bathroom and shower. Lake view from the front of property, unit is in the back overlooking wetlands. Plenty of parking, with enough room to bring a boat.

Popular amenities for Lake Nona vacation rentals

Quick stats about vacation rentals in Lake Nona

  • Total vacation rentals

    Explore 20 vacation rentals in Lake Nona

  • Nightly prices starting at

    Lake Nona vacation rentals start at ﺩ.ﺇ110 per night before taxes and fees

  • Verified guest reviews

    Over 350 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    20 of Lake Nona vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Lake Nona rentals

  • 4.5 Average rating

    Lake Nona stays receive an average rating of 4.5 out of 5 from guests

  1. Airbnb
  2. United States
  3. Florida
  4. Orange County
  5. Orlando
  6. Lake Nona Region