Guesthouse vacation rentals in Jefferson County

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Jefferson County

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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An open kitchen area is shown with light-colored walls and a wood countertop bar. Two wooden stools are positioned at the bar. A black couch is visible in the foreground, and large windows allow ample natural light into the space.

Guesthouse in Birmingham

4.52 out of 5 average rating, 114 reviews

Heated Towel Rack | Private Parking | Workspace

Welcome to your cozy Carriage House located in the Historic Norwood District, just 6 minutes from Birmingham’s Uptown and Downtown Entertainment Districts! This 1-bedroom, 1-bathroom garage apartment is designed to provide you with stylish comfort and convenience, making your stay truly exceptional. Perfect for business trips or weekend getaways. 🏥 Close to: ✔ University of Alabama at Birmingham (UAB) ✔ UAB Medical Center ✈️ Birmingham International Airport 🛣️ Easy access to major interstates

Top guest favorite

A tranquil backyard scene features a small fish pond surrounded by lush greenery and palm-like plants. Stone landscaping frames the pond, and a blue-green Adirondack chair is positioned nearby. The atmosphere reflects a serene outdoor space, ideal for relaxation.

Guesthouse in Vestavia Hills

4.96 out of 5 average rating, 114 reviews

Jimbo's LiL Casa

Take it easy at this unique and tranquil getaway. Close to everything with private backyard in quiet upscale safe neighborhood. Less than 10 mins to UAB, 4 mins to Samford, 15 mins to Summit. Enjoy this little two room home away from home with many amenities: Pool table bar kitchenette induction stove microwave air fryer fridge bathroom steam shower bidet patio fish pond grill cold plunge and hot tub (spring/summer). Cleaning fee included! 3% Airbnb fees not included. Hope you enjoy your stay!

A spacious kitchen and dining area are highlighted by blue cabinetry and a large black dining table. Seating for ten is provided, with white chairs arranged around the table. A relaxed seating area features large bean bag chairs. Natural light fills the room from multiple windows.

Guesthouse in Birmingham

4.43 out of 5 average rating, 21 reviews

The Bunglory: Lily In The Valley

Take a break & unwind @ this peaceful Lily In the Valley. This is the entire guesthouse but not the entire property. We live on property & have a few airbnb listings in the main house. But hey there’s plenty to share. This guesthouse was once a workshop, but now it’s a place for you & your group to relax & unwind in a natural woodsy setting. Come stay in the Lily where leaves, limbs, weeds may be aground or squirrels abound. Parking’s a coordinated feature so let’s discuss when you book

A separate studio guest house is depicted, featuring a wooden deck with two chairs and a gentle sloped entrance. Surrounding foliage and a stone wall border a landscaped yard, while a green bench is positioned near the house, providing an outdoor seating area.

Guesthouse in Birmingham

4.67 out of 5 average rating, 245 reviews

Studio Carriage House - Comfy, Private, Easy

Wonderful and separate studio guest house located just behind Rojo in Highland Park. Fully equipped with Kitchen, Bath, and Laundry, this studio has everything you need to have a comfortable, easy stay. washer/dryer, hairdryer, shampoo, Keurig coffee maker, dog kennel, and TV all available in the unit! We have wonderful parks and restaurants within walking distance. It’s a short drive to UAB, Pepper Place, Avondale, and the Coca-cola amphitheater!

Guest favorite

A serene bedroom features a spacious bed with a white quilt and plush pillows, flanked by wooden nightstands. Soft lighting is provided by lamps on each side. A bench is placed at the foot of the bed, complemented by folded towels, and natural wood flooring completes the inviting space.

Guesthouse in Birmingham

5 out of 5 average rating, 7 reviews

Charming Guest House in Historic Forest Park

Discover charming Forest Park in this fully renovated historic guest house located walking distance to hip restaurants, bars, and shopping. Nestled on a quiet street lined with mature trees and historical registered houses, you’ll be able to enjoy the peaceful elegance of Birmingham’s southern hospitality. It’s a short 10 minute drive to downtown and close to neighboring Mountain Brook and Homewood. You’ll love staying here!

Guest favorite

A charming carriage house is displayed, featuring a stone foundation and light grey exterior. A welcoming front porch with steps leads to the entrance. Windows are framed with white trim, enhancing the inviting appearance. Surrounding greenery adds a touch of nature to the setting.

Guesthouse in Birmingham

4.98 out of 5 average rating, 248 reviews

Private Carriage House in the heart of Birmingham

Private Carriage House above detached garage comfortably sleeps 2. Awesome location just minutes from downtown - perfect for exploring all that is Birmingham. UAB and plenty of local attractions close by including Avondale Brewery and Concert Venue, Highland Park Golf course, Vulcan Park, Railroad Park and many, many restaurants. Enjoy coffee on the front porch in the morning and relax on the side deck in the evening.