Vacation rentals in Guthrie County

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Top-rated vacation rentals in Guthrie County

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Guest favorite

A circular arrangement of six yellow chairs surrounds a small smokeless fire pit on a reddish-brown gravel surface. Dense greenery and tall trees form a natural backdrop, providing a shaded and serene atmosphere.

Cabin in Panora

4.92 out of 5 average rating, 13 reviews

Beautiful waterfront House at Lake Panorama

Relax with the whole family at this peaceful place surrounded by trees. Only 45 miles of Des Moines. Lake Panorama is a quiet, private and very fun lake. This house has private access to the lake and is located on a non-wake cove making perfect area for swimming and fishing. It comes with 2 kayaks, 2 paddle board, fishing poll, water inflatable, smokeless fire pit, ping pong, foosball table, theater room, Electric smoker charcoal grill. Community basketball, pickleball, volleyball, tennis court.

Guest favorite

A cabin features a sloped roof and is surrounded by trees and open grassland. A deck extends from the front, leading to an entrance. The landscape includes several green trees, adding a natural feel to the peaceful setting.

Place to stay in Guthrie Center

4.96 out of 5 average rating, 68 reviews

Seely Creek Cabin Getaway and Hunting Lodge

Seely Creek Cabin is a romantic getaway, a fabulous hunting destination, and a relaxing weekend spot! The cabin is nestled on 40 acres - 20 being wooded and another 20 open including a fully stocked pond and a walking trail! This beautifully unique property comes equipped with a fully stocked kitchen including all cooking necessities (except for food), a smart tv, wifi, games and cards in the entertainment center, as well as 3 comfy queen sized beds with all linens you would need!

Top guest favorite

A view from the outdoor patio showcases a manicured lawn bordered by trees, leading towards a serene lake. A red gravel path intersects the scene. A grill and a seating area are present on the patio, while an American flag gently waves in the breeze.

Home in Panora

4.92 out of 5 average rating, 12 reviews

Fire Creek Homes

Our condo at Lake Panorama National Golf Course is a quiet retreat for the entire family or golf buddies. We are located on the fairway of Hole #5 with a view of the lake. We have 3 bedrooms and 3 full bathrooms with laundry on site. A full size kitchen & living room makes this stay a comfortable experience in our 1,900 SF condo. Enjoy golf on the 18 hole course Lake Panorama National and you can also explore Lake Panorama, a 1,160 Acre Lake with 3 beaches for your enjoyment.

Guest favorite

A comfortable living area is presented, featuring a large sectional sofa positioned in front of a fireplace. A flat-screen television is mounted above the mantel, with natural light filtering through partially open curtains. Decorative plants and a coffee station add warmth to the space.

Townhouse in Panora

4.97 out of 5 average rating, 36 reviews

Spacious Getaway Townhome on Lake Panorama/Golf

Need a nice, relaxing week on the lake & golf course? Look no further! This is a spacious, 2 bedroom/2 bathroom townhome that has room to fit more. Walk out the back patio to Panorama's Golf Course hole 5 with a view of the lake and pond. Only a two minute walk to the swimming pool ($5/day fee), gym, conference center & Links Restaurant and Bar. Pickle ball, basketball, tennis, playground and beach access all within a 10 minute walk as well. #LocationLocationLocation

Guest favorite

A modern cabin is situated on a raised deck, surrounded by bare trees. Large windows allow for ample natural light, with warm sunset tones reflecting off the glass. The structure's clean lines and contrasting colors create a contemporary aesthetic within a forested setting.

Cabin in Stuart

4.91 out of 5 average rating, 67 reviews

Relaxing Cabin Getaway

Meet Olive: a cozy 750 sq. ft. cabin, nestled on 12 acres of peaceful forest just 30 minutes from West Des Moines and 90 minutes from Omaha. This two-bedroom, 1.5-bath retreat invites you to slow down and enjoy simple pleasures, with a spacious deck for fresh air, a hot tub to unwind, and a fully equipped kitchen for home-cooked meals. Perfect for couples, small groups or families, it’s a tranquil space to reconnect with nature and embrace a sense of hygge.

Top guest favorite

The rustic exterior of a cottage is showcased, with a wood-paneled facade and a front porch featuring two white chairs. Large windows allow natural light to enter, while an air conditioning unit is seen on the side. Lush greenery surrounds the property, illuminated by soft sunlight.

Cabin in Coon Rapids

4.98 out of 5 average rating, 307 reviews

The Rookery Cottage - Access scenic hiking trails

This rustic cottage is a quiet retreat in the heart of the Middle Raccoon River Valley. Situated on a private acreage within Whiterock Conservancy, guests can easily access 40mi+ of scenic hiking and mountain biking trails, float the nearby river, or enjoy dark sky viewing. A "rookery" is a nesting site for herons, a bird that prefers quiet, undisturbed habitat near water. And so the Rookery Cottage seeks to provide a natural escape from the daily grind.

A spacious dining area features a large wooden table surrounded by matching chairs. Warm wood paneling and flooring create a welcoming atmosphere. Adjacent to the dining space, a well-equipped kitchen can be seen, highlighted by stainless steel appliances and soft lighting.

Home in Adair

4.76 out of 5 average rating, 21 reviews

Warm, cozy 4 bedroom lodge-style country home

Located in the country just 8 miles north of I-80 Exit 76 between Des Moines and Omaha, this lodge-style, 4 bedroom, 2 1/2 bath home is the perfect place for a quiet weekend getaway. The home is perfectly decorated with a rustic, mountain cabin-y feel, with lots of seating for dining or playing games together, or relaxing on couches and chairs in the living room. There is a large patio outside to enjoy grilling or your cup of coffee in the sunshine.

Guest favorite

A well-lit room features a spacious bed with crisp linens and a decorative throw. A comfortable chair is positioned near large windows with vertical blinds, allowing natural light to filter in. A small dining table and kitchenette are visible, providing convenient amenities.

Vacation home in Panora

4.89 out of 5 average rating, 37 reviews

Feels Like Home Studio

A quiet and relaxing environment from the quick pace of your daily routine. Great location near Lake Panorama and on the Lake Panorama National Golf Course. Only blocks away from the club house and swimming pool. This is a wonderful place to get away from the city and enjoy a walk along the beach, a quick dip in the lake, or a round of golf. There are local establishments like The Penoach Vineyard or The Port with evening dinning and musical events.

Guest favorite

A bright and spacious living area features a combination of comfortable seating arrangements, including two sofas and a coffee table. A patterned rug adds texture to the hardwood floor, while potted plants bring a touch of greenery to the space.

Home in Panora

4.92 out of 5 average rating, 13 reviews

Water Front Lake House on Gorgeous Lake Panorama

This is a beautiful, comfortable water front lake home on gorgeous Lake Panorama. Spacious rooms with lots of windows allow you to enjoy the lake views any time of day or night. There is outdoor seating, a grill, and a fire pit on the patio. Two kayaks and a paddle boat are included, and there are boating and jet ski options as well. The property conveniently borders the lake, and the 18 hole National Golf Course is minutes away.

Top guest favorite

A light-filled kitchen features open shelving adorned with colorful glassware and decorative items. A modern refrigerator and pink microwave complement the white cabinetry. A central island with bar stools offers seating, while a floral arrangement adds a touch of charm.

Apartment in Stuart

4.99 out of 5 average rating, 136 reviews

The 1894 by Doe A Deer | 2 br, 1 bath apartment

Welcome to The 1894 by Doe A Deer - a newly renovated 2 bedroom spacious apartment located in historic downtown Stuart! Enjoy restaurants, boutiques and coffee just steps from the front door. Relax and enjoy the view from your new favorite small town spot. Perfect for getting ready with your wedding party, families, girls trips, anniversaries & more! We can’t wait to host you!

A modern kitchen area features black cabinetry and sleek stainless steel appliances. A large island with a white countertop is complemented by four black bar stools. A potted plant adds a touch of greenery, while a wall clock is mounted above the counter for convenience.

Apartment in Casey

5 out of 5 average rating, 3 reviews

Brick Street Loft

Welcome to Brick Street Loft! A newly renovated, open concept upper level 2 bedroom apartment in Historic downtown Casey. During your visit, you can experience local coffee, food and shopping. Relax and enjoy the view of the historic brick street. We have the perfect space for getting bridal parties, families, girls trips & more!

Top guest favorite

A spacious living area showcases a large fireplace surrounded by decorative candles. Large windows allow for natural light, with a cozy seating arrangement featuring a sectional sofa and a coffee table. Green plants add a touch of nature to the modern space.

Farm stay in Jamaica

4.94 out of 5 average rating, 233 reviews

Peaceful farm near bike trail

Modern home with beautiful views in all seasons, large fireplace and full kitchen. Four bedrooms (with 5 beds) and two bathrooms. Less than a mile from HWY 141, approx 1.5 miles from Jamaica, 7 miles to Perry and 50 miles from the Des Moines airport. A stone's throw from the Raccoon River Valley Trail.